1 results match your criteria: "Queen's University Kingston ON K7L 3N6 Canada jessop@queensu.ca.[Affiliation]"
CO-Assisted asymmetric hydrogenation of prochiral allylamines.
RSC Adv
February 2022
Department of Chemistry, Queen's University Kingston ON K7L 3N6 Canada
Article Synopsis
- A new method for the asymmetric hydrogenation of allylamines uses CO2 to prevent side reactions.
- Various factors like pressure, time, solvent, and base additives were analyzed to enhance enantioselectivity and conversion.
- The method achieved total conversion of 2-arylprop-2-en-1-amine with an enantiomeric excess of up to 82%, showing that the right choice of base improves selectivity in the reaction.