20 results match your criteria: "Queen's Heart Institute[Affiliation]"

Article Synopsis
  • This study explores the complexity and heterogeneity of systemic autoimmune diseases (SADs) by analyzing a large dataset of patients diagnosed with conditions like systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), and Sjögren's syndrome (SS) in Taiwan from 2001 to 2016.
  • Researchers used a joint cluster analysis method to categorize 11,923 patients into six distinct groups based on their immunomarkers, revealing that no cluster was solely made up of one type of SAD and that these groups exhibited significant differences in clinical features.
  • The findings highlight that this method can identify more relevant subgroups within SADs, suggesting it may enhance the accuracy of diagnoses
View Article and Find Full Text PDF

Background: There is ambiguity in the literature regarding the continuous suture technique (CST) for aortic valve replacement (AVR). At our center, there has been a gradual shift towards CST over the interrupted pledgeted technique (IPT). This study aims at comparing outcomes for both techniques.

View Article and Find Full Text PDF

Cliff diving leading to commotio cordis in a patient with Ebstein's anomaly.

J Cardiol Cases

December 2023

Department of Medicine, John A. Burns School of Medicine, University of Hawai'i, Honolulu, HI, USA.

Unlabelled: In this case report, we describe a 23-year-old male with Ebstein's anomaly who experienced out-of-hospital cardiac arrest due to commotio cordis following cliff diving. The patient previously underwent a Cone procedure and re-do reduction tricuspid valvuloplasty. Comprehensive investigations revealed no new ischemic events or structural abnormalities.

View Article and Find Full Text PDF

Eosinophilic myocarditis: systematic review.

Heart

April 2024

Department of Medicine, UH Mānoa JABSOM, Honolulu, Hawaii, USA

Objective: In clinical practice, patients with eosinophilic myocarditis (EM) may forgo the gold standard diagnostic procedure, endomyocardial biopsy (EMB), although it is highly recommended in guidelines. This systematic review aims to summarise current approaches in diagnosing and treating EM with a particular emphasis on the utilisation and value of alternative diagnostic methods.

Methods: Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement, we searched MEDLINE and EMBASE for all peer-reviewed articles using the keywords "eosinophilic myocarditis" from their inception to 10 September 2022.

View Article and Find Full Text PDF

Valve-sparing operations after Ross procedure: a single-center experience.

Ann Cardiothorac Surg

July 2023

Department of Cardiovascular & Thoracic Surgery, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain (UCL), Brussels, Belgium.

Background: The Ross procedure has demonstrated excellent long-term results, with restoration of life-expectancy in patients with severe aortic valve dysfunction. However, reintervention after Ross can occur, and herein we describe our center's experience with redo surgery after previous Ross procedures.

Methods: We searched our prospective database for aortic valve-repair and recruited all adult (≥18 years) patients who have undergone valve-sparing root replacements (VSRRs) and/or aortic valve-repair after Ross procedure between July 2001 and July 2022.

View Article and Find Full Text PDF

Background: Current guidelines recommend valve-sparing aortic root replacement (VSRR) procedures over valve replacement for the treatment of root aneurysm. The reimplantation technique seems to be the most widely used valve-sparing technique, with excellent outcomes in mostly single-center studies. The aim of this systematic review and meta-analysis is to present a comprehensive overview of clinical outcomes after VSRR with the reimplantation technique, and potential differences for bicuspid aortic valve (BAV) phenotype.

View Article and Find Full Text PDF

Three decades of reimplantation of the aortic valve-the Brussels experience.

Ann Cardiothorac Surg

May 2023

Department of Cardiovascular & Thoracic Surgery, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain (UCL), Brussels, Belgium.

Background: Over the last three decades, the importance of native valve preservation has increasingly become evident. Valve-sparing root replacement procedures, such as the reimplantation or remodeling technique, are therefore being progressively used for aortic root replacement and/or aortic valve repair. Herein, we are summarizing our single-center experience with the reimplantation technique.

View Article and Find Full Text PDF

The aortic valve (AV) is a three-dimensional structure, with leaflets that are suspended within the functional aortic annulus (FAA). These structures (AV and FAA) are therefore intrinsically connected and disease of just one component can independently lead to AV dysfunction. Hence, AV dysfunction can occur in the setting of entirely normal valve leaflets.

View Article and Find Full Text PDF

Penetrating cardiac injury: a narrative review.

Mediastinum

February 2023

Department of Surgery, University of Hawaii at Manoa John A. Burns School of Medicine, Queen's Heart Institute, Honolulu, HI, USA.

Background And Objective: Penetrating cardiac trauma is rare but can cause life-threatening complications. Survival is dependent on prompt diagnosis and treatment. Given the low incidence and life-threatening implications, it is difficult to study in large prospective studies.

View Article and Find Full Text PDF

Eosinophilic Myocarditis Presenting as Cardiac Tamponade: A Diagnostic Challenge.

Eur J Case Rep Intern Med

September 2022

Department of Medicine, John A. Burns School of Medicine, University of Hawaii, Honolulu, Hawaii, USA.

Unlabelled: Eosinophilic myocarditis (EM) is a rare cause of acute heart failure. It can occur secondary to drug hypersensitivity, autoimmune diseases such as vasculitis, idiopathic hypereosinophilic syndrome (HES) or malignancy, but is often under-recognized and underdiagnosed, being confused with other causes of heart failure. While EM is associated with various clinical symptoms, it is rarely associated with cardiac tamponade that requires urgent pericardiocentesis.

View Article and Find Full Text PDF

COVID-19 has recently been associated with the development of bradyarrhythmias, although its mechanism is still unclear. We aim to summarize the existing evidence regarding bradyarrhythmia in COVID-19 and provide future directions for research. Following the PRISMA Extension for Scoping Reviews, we searched MEDLINE and EMBASE for all peer-reviewed articles using keywords including"Bradycardia," "atrioventricular block," and "COVID-19″ from their inception to October 13, 2021.

View Article and Find Full Text PDF

Background: Gene expression profiling (GEP) and donor-derived, cell-free DNA (dd-cfDNA) measurement are alternative methods to endomyocardial biopsy (EMB) to monitor for rejection following heart transplantation. We aim to describe our use of GEP and dd-cfDNA in heart transplant recipients > 1-year post-transplantation.

Methods: This is a single-center, retrospective study in post-transplant recipients.

View Article and Find Full Text PDF

Subclinical hypothyroidism (SCH) has been found to be associated with an increased risk of cardiovascular diseases. However, there is no clear consensus on the relationship between SCH and hypertension (HTN). We sought to investigate the association between SCH and incident HTN in women.

View Article and Find Full Text PDF

The Avalon Elite catheter (Maquet Cardiopulmonary, Rastatt, Germany) is a bicaval catheter for single-site cannulation that can be used in the initiation of venovenous extracorporeal membrane oxygenation (ECMO) or as a transition from venoarterial ECMO. We report a unique complication of tissue obstructing the outflow aperture during insertion. ().

View Article and Find Full Text PDF

Thrombocytopenia with absent radii (TAR) syndrome is a rare genetic condition causing absent radial bones and thrombocytopenia. Management is generally supportive although there may be a role for platelet-stimulating agents such as romiplostim. In this case, we highlight the obstacles in managing end-stage heart failure in a patient with TAR syndrome.

View Article and Find Full Text PDF

Transthyretin cardiac amyloidosis results from the deposition of transthyretin amyloid fibrils in the myocardium. This happens because of the misfolding of genetically normal (wild type - ATTR) or mutant (hereditary ATTR) transthyretin. The clinical presentation of hereditary ATTR cardiac amyloidosis is dependent on the exact site of the amino acid substitution.

View Article and Find Full Text PDF