Construction of prediction model of early glottic cancer based on machine learning.

Background: The early diagnosis of glottic laryngeal cancer is the key to successful treatment, and machine learning (ML) combined with narrow-band imaging (NBI) laryngoscopy provides a new idea for the early diagnosis of glottic laryngeal cancer.

Objective: To explore the clinical applicability of the diagnosis of early glottic cancer based on ML combined with NBI.

Material And Methods: A retrospective study was conducted on 200 patients diagnosed with laryngeal mass, and the general clinical characteristics and pathological results of the patients were collected.

Alterations of gut microbiome in eosinophilic chronic rhinosinusitis.

Purpose: A growing body of evidence has elucidated that the gut microbiota has a crucial impact on the pathophysiological process of atopic diseases. Eosinophilic chronic rhinosinusitis with nasal polyps (eCRSwNP) is a local atopic disease of the systemic immune response. Alterations in the gut microbiome in eCRSwNP patients remain largely undefined.

Perichondritis of the auricle: bacterial or fungal? (A case series).

Background: Suppurative perichondritis of the auricle is a common disease that can easily cause malformations if it develops into an uncontrolled infection. In nearly half of the cases, otolaryngologists cannot identify the pathogens involved.

Case Presentation: In the present work, we described two cases of pyogenic perichondritis, with negative on conventional culture.

Effect of Smoking on Cepstral Parameters.

Smoking exerts certain damage to the voice, which affects sound characteristics. This study explored the effects of smoking, smoking time, and smoking amount on cepstral parameters. We collected the acoustic signals of sustained vowels in 301 participants (135 smokers and 166 nonsmokers).

Three-dimensional characteristics of nystagmus induced by low frequency in semicircular canals of healthy young people.

Objective: The study aimed to analyze the three-dimensional characteristics of nystagmus induced by different semicircular canal combinations in healthy young people, and to determine the reference range of nystagmus slow phase velocity (SPV) and its asymmetry.

Materials And Methods: Fifty-two healthy volunteers (26 males and 26 females, aged 17-42 years, average 23.52 ± 6.

Characteristics of spontaneous nystagmus and its correlation to video head impulse test findings in vestibular neuritis.

Objective: To explore the direction and SPV (slow phase velocity) of the components of spontaneous nystagmus (SN) in patients with vestibular neuritis (VN) and the correlation between SN components and affected semicircular canals (SCCs). Additionally, we aimed to elucidate the role of directional features of peripheral SN in diagnosing acute vestibular syndrome.

Materials And Methods: A retrospective analysis was conducted on 38 patients diagnosed with VN in our hospital between 2022 and 2023.

[Further exploration of the classification and clinical value of head-shaking nystagmus].

To investigate the classification of head shaking nystagmus（HSN） and its clinical value in vestibular peripheral diseases. Clinical data of 198 patients with peripheral vestibular disorders presenting with HSN were retrospectively analyzed. Video Nystagmograph（VNG） was applied to detect spontaneous nystagmus（SN）, HSN, and Caloric Test（CT）.

Targeting Aurora-A inhibits tumor progression and sensitizes thyroid carcinoma to Sorafenib by decreasing PFKFB3-mediated glycolysis.

Thyroid cancer (TC) is the most common endocrine tumor, amongst which anaplastic thyroid carcinoma (ATC) is the most deadly. Aurora-A usually functions as oncogenes, and its inhibitor Alisertib exerts a powerful antitumor effect in various tumors. However, the mechanism of Aurora-A in regulating TC cell energy supply remains unclear.

The Role of IL-6 in Inner Ear Impairment: Evidence from 146 Recovered Patients with Omicron Infected in Tianjin, China.

Purpose: To explore the effect of inflammatory factors on inner ear impairment in a sample of Omicron-infected patients with a high rate of vaccination in China.

Methods: One hundred and forty-six recovered Omicron-infected patients performed the distortion product otoacoustic emission (DPOAE) test and serum test for inflammatory factors; demographic data and vaccination statuses were collected from the questionnaire.

Results: Out of 146 patients, the DPOAE pass rate was 81.

Alterations of nasal microbiome in eosinophilic chronic rhinosinusitis.

Background: Exposure to microbes may be important in the development of chronic rhinosinusitis (CRS). Dysbiosis of the nasal microbiome is considered to be related to CRS with nasal polyps (CRSwNP). The link between the nasal microbiota and eosinophilic CRSwNP (eCRSwNP) has rarely been studied.

invasive rhinosinusitis in an elderly patient: diagnosis and treatment.

is a ubiquitous organism present in the environment and is rarely identified in rhinosinusitis. We report a case of invasive rhinosinusitis with which made a definite diagnosis by metagenomic next-generation sequencing (mNGS) from a biopsy sample. The resection of the pathological mass was performed with low-temperature plasma radiofrequency ablation.

The 3D characteristics of nystagmus in posterior semicircular canal benign paroxysmal positional vertigo.

Objective: The aim of this study was to observe the 3-dimensional (3D; horizontal, vertical, and torsional) characteristics of nystagmus in patients with posterior semicircular canal canalithiasis (PSC-can)-related benign paroxysmal positional vertigo (BPPV) and investigate its correlation with Ewald's.

Methods: In all, 84 patients with PSC-can were enrolled. The latency, duration, direction, and slow-phase velocity induced by the Dix-Hallpike test in the head-hanging and sitting positions were recorded using 3D video nystagmography (3D-VNG).

The horizontal and vertical components of nystagmus evoked by the supine roll test in horizontal semicircular canal canalolithiasis.

Objective: The characteristics of horizontal and vertical components of nystagmus evoked by the supine roll test in patients with horizontal semicircular canal canalolithiasis (HSC-Can) were analyzed, according to Ewald's first law. It provided a basis for the study of human horizontal semicircular canal function and structure, objective diagnosis, and treatment of benign paroxysmal positional vertigo (BPPV).

Materials And Methods: The records of patients that had been tested with 2-dimensional videonystagmography (2D-VNG) were reviewed between June 2019 and June 2021.

Nasal Sinus Mucoceles Manifesting Ocular Symptoms.

Introduction: To describe the ocular symptoms in a series of patients with nasal sinus mucoceles of different locations.

Methods: The authors analyzed the diagnosis and treatment of patients with sinus mucoceles and ocular symptoms who presented to the hospital from February 2010 to April 2020. A total of 61 patients were included in the study.

Interleukin-6 affects the severity of olfactory disorder: a cross-sectional survey of 148 patients who recovered from Omicron infection using the Sniffin' Sticks test in Tianjin, China.

Objectives: The mechanism of olfactory disorder (OD) in patients with COVID-19 is unclear. Our study aimed to elucidate the relationships between inflammatory factors and OD in a sample of patients infected with the Omicron variant, with a high vaccination rate in China.

Methods: The Sniffin' Sticks 12-item test was performed in a cross-sectional study of 148 recovered patients who were infected with the Omicron variant to evaluate OD severity.

[Detection of speech pathology based on parameters of analysis of dysphonia in speech and voice].

To analysis speech pathology based on dysphonia in speech and voice（ADSV）. The acoustic signals of continuous vowels and continuous speech of one-hundred and thirteen individuals were collected, including 93 vocal cord polyps cases, 20 glottis laryngeal carcinoma cases and 47 volunteers without speech sound disorders. Cepstral peak prominence（CPP）, CPP standard deviation（CPP SD）, L/H spectral ratio（L/H ratio）, L/H ratio standard deviation（L/H ratio SD） and cepstral/spectral index of dysphonia（CSID） were analyzed by ADSV to explore the role of these parameters in the recognition of speech pathology.