Preparation of Baicalin Liposomes Using Microfluidic Technology and Evaluation of Their Antitumor Activity by a Zebrafish Model.

Baicalin (BCL), a well-known flavonoid molecule, has numerous therapeutic applications. However, its low water solubility and bioavailability limit its applicability. Microfluidics is a new method for liposome preparation that provides efficient and rapid control of the process, improving the stability and controllability.

A 2-fold interpenetrating 3D pillar-layered MOF for the gas separation and detection of metal ions.

A 2-fold interpenetrating 3D pillar-layered MOF, which was assembled from a mixed-linker and paddle-wheel cluster, was successfully synthesized. It possesses good thermal and water stability as well as high selectivity for CH over CH and CO over N under ambient conditions, which was further proved by breakthrough experiments. Moreover, this porous material exhibits good detection of Cu, [Co(NH)] and Fe in an aqueous solution.

Synergistic Coordination Effect and Metal-Support Interaction Engineering of Single-Atom Mn-N Sites for Boosting Sensitive and Selective Dopamine Biosensing in Human Serum.

Coordination environment of metal atoms is core for designing high-performance single-atom catalysts (SACs), while metal-support interaction also has an important effect on structure-function relationship. Nevertheless, the interaction effect of metal-support is mostly ignored. Through synergistic regulation of coordination environment and metal-support interaction, Mn SAC with atom-dispersed Mn-N sites on dopamine (DA) support is synthesized for sensitive and selective DA oxidation based on theoretical calculations and experimental explorations.

Magnetoelectric Tuning of 2D Ferromagnetism in 1T-CrTe through InSe Substrate.

Electric field control of two-dimensional (2D) materials with optimized magnetic properties is not only of scientific interest but also of technological importance in terms of the functionality of various nanoscale devices. Here, we report the multiferroic control of the 2D ferromagnetism in 1T-CrTe monolayer through a ferroelectric InSe sublayer. Our results reveal the effect of polarization switching on the electronic structures and magnetic properties of 1T-CrTe/InSe heterostructures, enabling effective manipulation of their magnetic anisotropy energy (MAE) and magnetization orientation.

How online healthcare team evolve into organization: A social network analysis.

Objective: The rapid development of online healthcare has greatly promoted the transformation of healthcare service. The effectiveness of online healthcare is enhanced by the team that supports the doctor-patient connection. However, extant researches lack the comprehensive analysis of social networks within online healthcare team.

A membrane-anchored fluorescent probe for the detection of pH in living cells and NAFLD.

The abnormal pH in cell membranes can lead to disorder in membrane structure and permeability, and is also an important signal of cell cancer. The acidification of the cell membrane can lead to the disorder of cell lipid metabolism and lead to non-alcoholic fatty liver disease (NAFLD). However, fluorescent probes to detect the cell membrane pH have rarely been reported, let alone used to study NAFLD.

Cellulose fiber drainage improvement via citric acid crosslinking.

Wheat straw, as a non-wood fiber waste, is available worldwide and can be used in cellulosic matric production, promoting the application of sustainable materials. However, poor fiber properties and water drainage are the primary obstacles to its utilization. In this study, wheat straw pulp fibers were chemically crosslinked by citric acid (CA) in an environmentally friendly process.

Study on the adsorption process and kinetic, thermodynamic of bio-based waste cattle hair powder toward acidic complex dye.

In this paper, cattle hair waste (CHW) was collected and physically milled into different meshes of ultrafine cattle hair powder (UCHP). The reuse of CHW reaches the purpose of treating pollution with waste by using bio-base adsorbent. It was characterized by using scanning electron microscope-energy dispersive spectrometer (SEM-EDS), Fourier transform infrared (FT-IR) spectroscopy, X-ray photoelectron spectroscopy (XPS), thermogravimetric analysis (TGA), differential scanning calorimeter (DSC), and X-ray diffraction (XRD).

Designing High-Performance Nanoscale Spin-MOSFET Devices by Using Two-Dimensional Half-Metallic CrSe.

Constructing nanoscale spin devices has been a crucial pursuit in the field of nano spintronics. Here, by using the density functional theory (DFT) and nonequilibrium Green's function (NEGF) method, high-performance nanoscale spin-MOSFET devices using half-metallic 2D CrSe as electrodes are theoretically designed. Specifically, seven typical two-dimensional (2D) semiconductors, Sb, Bi, BP, BAs, MoTe, WTe, and WSeTe (with two different contacting surfaces), are considered here as the channel materials.

Interfacial modulation of TiCT MXene using functionalized cellulose nanofibrils for enhanced electrochemical actuation.

Electrochemical actuators (ECAs) with low voltage actuation and large deformation ranges generally require electrode materials with high ion kinetic energy transport, high charge storage, and excellent electrochemical-mechanical properties. However, the fabrication of such actuators remains a major challenge. In the present work, hybrid electroactive films were fabricated by self-assembling one-dimensional functionalized cellulose nanofibrils (CNFs) with two-dimensional MXene (TiCT).

Control Patterning of Cyanobiphenyl Liquid Crystals for Electricity Applications.

Controlling molecular self-assembly from organic solution evaporation is an important strategy for developing many functional materials and systems. In this work, it is demonstrated that 4-octyloxy-4'-cyanobiphenyl (8OCB) liquid crystals can be patterned into well-oriented stripes with very high micrometer-scale precision using a sandwich system through a dewetting method. The preparation temperature, concentration, and surface energy are combined to control the morphology and orientation of 8OCB microstripe arrays assisted by silicon micropillars.

Promoting effects of bioplastics and sludge anaerobic co-fermentation for carboxylates production with pH regulation: Insights into the plastic structure, microbial metabolic traits, and adaptive mechanism.

Biodegradable plastics (BPs) are presenting new challenges for their reutilization. This work found that volatile fatty acids (VFAs) production by co-fermentation of BPs with waste activated sludge (WAS) reached 4-37 times of the WAS fermentation alone, which was further amplified by pH regulation (especially alkaline regulation). Moreover, the VFAs composition is highly associated with BPs category.

Mechanism of carbonized humic acid and magnesium aluminum-layered double hydroxide promoting biohydrogen generation.

Dark fermentation (DF) is prone to low hydrogen (H) yield. In this work, magnesium aluminum-layered double hydroxide and carbonized humic acid (MgAl-LDH/CHA) was synthesized by co-precipitation to reveal the mechanism in rising bioH generation. The results indicated that MgAl-LDH released Mg and Al ions slowly in DF system, improving the activity of H-producing microbes (HPM) for more H.

3D Printed Magnetoelectric Composites for Personalized Wearable Multifunctional Sensors.

Traditional fabrication methods for creating flexible magnetoelectric sensors are often laborious and challenging when it comes to personalization. This article employs fused deposition modeling 3D printing technology to produce flexible multifunctional sensors. (0-3) type composite filaments were prepared using polyvinylidene fluoride and cobalt ferrite (CoFeO, abbreviated as CFO).

Strength, pliability, and hydrophobicity of mung bean starch straws: Orientation change caused by annealing time.

To achieve starch straws with high strength and large toughness, the effects of annealing time on structural and functional performances of mung bean starch straws were studied. The results revealed that with increasing annealing time from 0to 60 min, the ratios of 1047 cm/1022 cm in Fourier transform infrared spectroscopy decreased from 1.37 to 1.

Continuous augmentation of anaerobic digestion with electroactive microorganisms: Performance and stability.

The performance and stability of a bioelectrochemical anaerobic digester (BeAD), continuously augmented with electroactive microorganisms (EAMs), were investigated. The BeAD showcased superior performance, sustaining the high COD removal efficiency and methane production rate of 76.5 % and 0.

Preparation and release pattern study of long-term controlled release Blonanserin microspheres.

To prepare a PLGA microsphere loaded with the antipsychotic Blonanserin without release leg period and released in a near-zero model for long time, in this study, 15 kDa and 75 kDa PLGA were chosen to be mixed with different ratios, and Blonanserin microspheres (Bn-MS) without significant differences in the particle size, drug loading capacity, and encapsulation rate were prepared by microfluidics. The release kinetic model was fitted to the release behavior by monitoring the changes in particle size and morphology during the Bn-MS release to investigate microspheres' in vitro release pattern. The results showed that the addition of appropriate ratios of mixed molecular weights to Bn-MS could eliminate the release hysteresis period.

Preparation and Properties Study of CsPbX@PMMA Luminescent Resin.

Perovskite as an emerging semiconductor luminescent material has attracted widespread attention due to its simple preparation, high luminescence quantum yield, high color purity, tunable spectrum, and ability to cover the entire visible light band. However, due to the influence of water or other highly polar solvents, oxygen, temperature, and radiation, perovskite nanocrystals will aggregate or collapse in the lattice, eventually leading to luminescence quenching. This study starts from the postprocessing of perovskite, uses methyl methacrylate as the monomer and TPO as the photoinitiator, and encapsulates the perovskite powder prepared by the hot injection method through ultraviolet light initiation.

Spatial Metabolomics Profiling Reveals Curcumin Induces Metabolic Reprogramming in Three-Dimensional Tumor Spheroids.

Curcumin is widely recognized for its diverse antitumor properties, ranging from breast cancer to many other types of cancers. However, its role in the tumor microenvironment remains to be elucidated. In this study, we established a 3D tumor spheroids model that can simulate the growth environment of tumor cells and visualized the antitumor metabolic alteration caused by curcumin using mass spectrometry imaging technology.