145 results match your criteria: "Qilu Institute of Technology[Affiliation]"

Fluorescent carbon quantum dots (CDs) have received widespread attention for their potential applications in optical sensing. Meanwhile, as the importance of mercury ion (Hg) detection in the environment, the exploration of Hg fluorescent nanosensor based on CDs with high quantum yield is particularly intriguing. Herein, nitrogen-doped carbon quantum dots (N-CDs) were prepared by microwave method using citric acid as carbon source and urea as nitrogen source, and glycerol as microwave solvent.

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This study investigates the therapeutic effects of recombinant human IL-10 (rhIL-10) administered via aerosol inhalation in acute lung injury (ALI), with a particular focus on neutrophils. It explores how rhIL-10, in the presence of platelets, modulates neutrophil polarization to ameliorate acute lung injury. Initially, the ALI model established in mice demonstrated that aerosol inhalation of rhIL-10 significantly mitigated the cytokine storm in the lungs, reduced pulmonary edema, and alleviated histopathological damage to lung tissue.

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Deep learning methods have shown significant potential in tool wear lifecycle analysis. However, there are fewer open source datasets due to the high cost of data collection and equipment time investment. Existing datasets often fail to capture cutting force changes directly.

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Tin-based sulfides, possessing a unique layered structure and a high theoretical capacity, stand as highly prospective contenders for anode materials in lithium-ion batteries (LIBs). Nevertheless, the pronounced volume expansion that occurs during lithium storage and poor capacity retention have limited its progress toward commercialization. Herein, we designed and prepared a SnS/RGO composite with a three-dimensional porous structure by sulfurizing the SnO(OH)/GO precursor.

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When utilizing convolutional neural networks for wheat disease identification, the training phase typically requires a substantial amount of labeled data. However, labeling data is both complex and costly. Additionally, the model's recognition performance is often disrupted by complex factors in natural environments.

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Recent advances targeting chemokines for breast cancer.

Int Immunopharmacol

December 2024

College of Biological and Chemical Engineering, Qilu Institute of Technology, Shandong, China; College of Biotechnology, Tianjin University of Science and Technology, Tianjin, China. Electronic address:

Breast cancer (BC) is a complex and heterogeneous disease, and its onset and progression involve the interplay of multiple molecular mechanisms. Chemokines and their receptors are key regulators of cell migration and immune responses and contribute significantly to the pathophysiology of BC. This article reviews the classification, functions, and mechanisms of chemokines and their receptors in the proliferation, migration, invasion, and angiogenesis of BC cells.

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Objective: This study aimed to explore the risk factors for gastrointestinal side effects (GISEs) in patients with type 2 diabetes mellitus (T2DM) during treatment with glucagon-like peptide-1 receptor agonists (GLP-1RAs) based on real-world data and to develop a prediction model for GLP-1RA-related GISEs.

Methods: A total of 855 patients who attended the First Affiliated Hospital of Shandong First Medical University from January 2020 to May 2023 were selected as the study participants, who were divided into the training set (598 cases) and the validation set (297 cases) using a simple random sampling method at a ratio of 7:3. The general information and biochemical indicators of the participants were collected to assess the risk factors for GLP-1RA-related GISEs, and multifactorial logistic regression analysis was used to obtain the best predictors.

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Anaerobic digestion is a sustainable technology for methane (CH) production from organic waste and wastewater. However, its performance is frequently hindered by excessive acidification in readily acidified substrates, such as starch wastewater. Oyster shell (OS), a natural alkaline material, effectively regulates pH and enhances CH production.

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Background: Stroke ranks as the second leading cause of death worldwide. Meanwhile, headaches are considered the second leading cause of disability, and they often occur as a stroke complication. However, insufficient attention has been given to the treatment and rehabilitation of headaches among stroke patients, and the research on the epidemiology and risk factors of headaches in stroke patients in China is limited.

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The coordination effect of organic ligands in Ce-MOF brings about atomically dispersed Fe in CeO for TAC detection in commercial samples.

Talanta

December 2024

School of Chemistry and Materials Science, Shandong Agricultural University, No. 61 Daizong Street, Taian, 271000, PR China; School of Food Science and Engineering, Shandong Agricultural University, No. 61 Daizong Street, Taian, 271000, PR China. Electronic address:

Reducing the size of active species is a powerful means to improve the utilization rate of active metals and enhance the properties of bimetallic nanozymes. In this work, Fe was introduced into Ce-MOF through the coordination of Fe and organic ligands, and the coordination effect resulted in atomically dispersed Fe in the derived Fe/CeO nanozyme. Due to the atomically dispersed Fe embedded in the lattice of CeO, a large number of defect sites were generated, endowing the nanozyme with excellent peroxidase (POD)-like activity.

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The Internet of Things (IoT) is a sophisticated network of objects embedded with electronic systems that enable devices to collect and exchange data. IoT is a recent trending leading technology and changing the way we live. However, it has several challenges especially efficiency, architecture, complexity, and network topology.

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Background: The disease impact of breast cancer is to view the couple as a whole, breast cancer is a disease shared by the couple. Cancer coping has evolved from an individual perspective to a dyadic coping perspective for couples. The purpose of this study was to identify and describe the dyadic coping categories of couples with breast cancer and to analyze the relationship between dyadic coping categories and post-traumatic growth (PTG) in couples with breast cancer.

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Objective: To investigate the mechanism of liraglutide affecting lipid metabolism by regulating lipolysis and lipogenesis in cells and ob/ob mice.

Methods: 3 T3-L1 cells were treated with liraglutide in vitro, and differentially expressed genes were screened by RNA sequencing. Gene Ontology (GO) and KEGG (Kvoto Encyclopedia of Genes and Genomes) enrichment analyses identified target genes for lipid regulation of liraglutide.

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Background: Existing studies have shown that transferrin receptor (TfR) is highly expressed on the surface of lung cancer cells, and nanoparticles (NPs) have been widely used as delivery vehicles. The aim of this study was to investigate the effect of the targeted delivery of FeO NPs modified with transferrin (Tf) compared with photothermal treatment for lung cancer.

Methods: The morphology and properties of Fe3O4 NPs modified with Tf were tested by internal morphological characterization experiments including transmission electron microscopy, particle size meter infrared spectrometer and other experiments.

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Article Synopsis
  • Intestinal barrier damage and oxidative stress are key issues in ulcerative colitis (UC), and this study investigates the effects of fucoidan from Stichopus chloronotus (FucSc) on UC caused by dextran sulfate sodium (DSS).
  • The research showed that FucSc treatment improved the integrity of intestinal cells, boosted protective proteins, and activated antioxidant pathways, helping cells resist oxidative damage.
  • Additionally, when administered orally, FucSc reduced symptoms like weight loss and colon damage in UC, highlighting its potential as a beneficial dietary supplement for managing colitis.
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The treatment of water contaminated with oil or organic solvents has always been a thorny challenge, considering the complexity of water pollution, the susceptibility to secondary pollution and the consequent depletion of resources. Biomass is a versatile, green and self-circulating natural material that shows important potential in designing high-performance oil/water separation materials. This review highlights the recent research progress on biomass-based materials (BBMs) in the field of oil-water separation.

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Catalytic materials are considered pivotal in addressing the sluggish kinetics and shuttle effect in lithium-sulfur batteries (LSBs). However, effectively harnessing the utilization rate of active sites within catalytic materials remains a pivotal challenge. In this study, a novel conductive nitrogen-doped graphene-loaded tungsten oxynitride nanoparticle (WNO/NG) with abundant active sites is prepared through a polymer-assisted templating method for serving as a sulfur host.

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Background: Transmembrane p24 trafficking protein 9 () belongs to the TMED family, and its overexpression frequently induces cancer. Studies have demonstrated the association between the overexpression of and cancer development and proliferative migration in cancers such as ovarian cancer, hepatocellular carcinoma, and breast cancer. However, there has been no study investigating the clinical value, biological function, and anti-tumor immune effects of from a pan-cancer perspective.

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Tandem Cyclization of -Hydroxyphenyl Propargyl Alcohols with Thionucleophiles: A Metal-Free and Modular Access to 3-Fluoroalkylsulfonyl/Thio Benzofurans.

J Org Chem

December 2024

College of Chemistry, Chemical Engineering and Materials Science, Collaborative Innovation Center of Functionalized Probes for Chemical Imaging in Universities of Shandong, Key Laboratory of Molecular and Nano Probes, Ministry of Education, Institute of Molecular and Nano Science, Shandong Normal University, Jinan 250014, China.

Despite both fluoroalkylsulfonyl groups and benzofurans are important bioactive moieties, the construction of fluoroalkanesulfonylated benzofurans that incorporate these two fragments remains underdeveloped. Here, we report a tandem cyclization protocol to construct a wide range of 3-fluoroalkylsulfonyl benzofurans using readily accessible -hydroxyphenyl propargyl alcohols and sodium fluoroalkanesulfinates. Furthermore, this synthetic strategy can also be adapted to prepare 3-thio benzofurans by changing the S-nucleophiles to thiols or thiophenols.

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CuO@PdCu synergistic catalysis for highly effective C-H arylation of azoles.

Chem Commun (Camb)

November 2024

International Collaborative Laboratory of 2D Materials for Optoelectronics Science and Technology of Ministry of Education, Institute of Microscale Optoelectronics, Shenzhen University, Shenzhen 518060, P. R. China.

An efficient heterogeneous Pd/Cu synergistic catalysis system without a ligand was utilized for C-H arylation of azoles. The reaction exhibits excellent catalytic activity with high functional group tolerance. The synergistic effect between the CuO core and PdCu shell was confirmed, whereas pure PdCu nanocages and CuO exhibited negligible catalytic activity.

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Revealing the intrinsic mechanism of the influence of different rings and oxidized structures on the room temperature phosphorescence.

Spectrochim Acta A Mol Biomol Spectrosc

February 2025

Tianjin Key Laboratory of Molecular Optoelectronic Sciences, Department of Chemistry, School of Science, Tianjin University, Tianjin 300354, China. Electronic address:

In this work, we used density functional theory (DFT) and time-dependent density functional theory (TD-DFT) methods to study the mechanism of pure organic room temperature phosphorescence emission. The effects on the electronic structure and photochemical properties of thiophene and diketone derivatives with different cyclic and oxidized structures. The result suggests that varying ring configurations and oxidation products significantly influence the photochemical characteristics of thiophene and diketone derivatives.

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Article Synopsis
  • - A new covalent organic framework (COF) material called RuCOFs was developed for use in electrochemiluminescence (ECL) sensors, combining specific components for enhanced performance.
  • - RuCOFs improve the stability of ECL signals and include features that allow for effective detection of metal ions, specifically mercury (Hg⁺) and zinc (Zn⁺).
  • - The sensors demonstrated high sensitivity, detecting Hg⁺ at 4.71 nM and Zn⁺ at 6.57 nM, showcasing their potential for environmental monitoring of metal ion pollution.
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This paper discusses the seismic performance of five reduced-scale shear walls, including one cast-in-place (CIP) concrete shear wall, two precast concrete (PC) shear walls with overlapping U-bar loop connections, and two PC shear walls with modified form-overlapping U-bar loop connections combined with extruded sleeve connections. A quasi-static test was conducted to evaluate the reliability of the overlapping U-bar loop connections and the modified form by comparing the corresponding mechanical parameters of PC specimens with those of the CIP specimen. Moreover, the differences in seismic performance between the CIP specimen and PC specimens with different connection methods were also analyzed in terms of damage process, hysteretic loops and skeleton curves, load carrying capacity, ductility, equivalent stiffness, and energy dissipation.

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