25,025 results match your criteria: "Qatar; University of Leicester[Affiliation]"

Introduction: Fibromyalgia is a chronic condition often accompanied by cognitive impairments, such as difficulties with sustained attention, and emotional disturbances, particularly depression and anxiety. Understanding how these emotional and cognitive factors interact is crucial to improving treatment for fibromyalgia patients. This study aimed to investigate the network structure of these interactions, focusing on the relationship between depression, anxiety, and cognitive performance.

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Large vessel vasculitis (LVV) is a group of inflammatory diseases that affect the aorta and its major branches, causing stenosis, aneurysms, or dissections. LVV can be associated with various disorders, such as IgG4-related disease, Takayasu arteritis, giant cell arteritis, and Behcet's disease. Aneurysms due to Behcet's disease are rare and challenging to manage, as they have high rates of morbidity and mortality.

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Background: Familial Mediterranean fever (FMF) is an autosomal recessive disease caused by mutations in the MEFV gene and is characterized by recurrent febrile episodes of abdominal pain, chest pain, and joint involvement. We aim to study the clinical and genetic features of FMF in Moroccan children and to establish a phenotype-genotype correlation in this group of patients.

Methods: A total of 35 patients were included in this study.

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Background: Health system satisfaction is an important but understudied indicator of health system performance. It has far-reaching implications for sustainability but has been widely understudied particularly for non-European settings. Qatar represents a growing international experience of rapid development requiring steadfast system funding and reorganisation.

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Article Synopsis
  • Patchy data on litter decomposition in wetlands limits understanding of carbon storage, prompting a global study involving over 180 wetlands across multiple countries and climates.
  • The study found that freshwater wetlands and tidal marshes had more organic matter remaining after decay, indicating better potential for carbon preservation in these areas.
  • Elevated temperatures positively affect the decomposition of resistant organic matter, with projections suggesting an increase in decay rates by 2050; however, the impact varies by ecosystem type and highlights the need to recognize both local and global factors influencing carbon storage.
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Background: Homestay accommodations aim to support a smoother transition for refugees; yet, the intricate nature of relationships between refugees and their hosting families can make this process complex, which, in turn, can affect their health and well-being. It is crucial to grasp the experiences of both refugees and their host families in order to foster effective settlement, integration, and well-being.

Objective: The purpose of this scoping review is to explore the dynamics of homestay or hosting with a focus on understanding the experiences of both refugees and their hosting families to identify gaps in the literature and propose directions for future research.

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Background: Faculty development programs (FDPs) in health profession education (HPE) impact teaching in different ways. There has been limited literature on the impact of such programs in developing countries. This qualitative study explores the experiences, perceptions, and recommendations of faculty attending these FDPs.

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Background: Obesity is an increasing health concern, affecting 39% of the population. In Qatar, in recent years, the obese population contributed 35.9% of men and 46.

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Background: Electronic medical records (EMRs) have become highly customizable. Although customization allows changes for workflow optimization, such changes can result in a less standardized system and create barriers due to individual preferences.

Aim: This was a documentation of the efforts of a greenfield academic medical centre in Qatar to improve patient safety, physician operational efficiency and revenue capture by standardizing the design of the non-medication orders and associated revenue of the EMR .

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Background: Harnessing digital technology for health service provision is inevitable, especially after the dramatic increase in demand during the COVID-19 pandemic and the observed global disruption of health services especially for People Living with Noncommunicable Diseases (PLWNCDs).

Aims: To document and share experiences, challenges and lessons learned from the use of digital health interventions (DHIs) for noncommunicable disease (NCD) service delivery during the COVID-19 pandemic in the Eastern Mediterranean Region (EMR).

Methods: We conducted a documentary research on the use of DHIs for continuity of NCD services during the COVID-19 pandemic in EMR.

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Refractory status epilepticus (RSE) is a condition with serious mortality and morbidity rate, resistant to benzodiazepine and second-line antiepileptic drugs. This study aimed to electrophysiologically investigate the combination of NMDA receptor antagonist ketamine and GABAergic agent propofol in an RSE model induced by lithium-pilocarpine in male Sprague-Dawley rats. Seventy-two male Sprague-Dawley rats were divided into nine groups.

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 Acute medical unit (AMU) is a dedicated facility to treat patients with acute medical conditions requiring a short hospital stay (< 72 hours) with the support of a multidisciplinary team led by a medical consultant. We aim to present a study of the AMU model of care from Qatar to provide insight into its effects on patient care and management.  Retrospective data from AMU facility at Hamad General Hospital (HGH), Doha, Qatar, was collected from January 2019 to December 2020 from the electronic patient record.

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Mpox, formerly known as Monkeypox, is a viral zoonotic disease endemic to Central and West Africa that has posed significant public health challenges since its identification in 1970. Despite decades of experience in managing outbreaks, the 2022-2024 Mpox outbreaks exposed substantial gaps in global preparedness and response, leading the World Health Organization (WHO) to declare a Public Health Emergency of International Concern (PHEIC) in 2022. The resurgence of cases in Europe in 2022 and the more recent emergence of the virulent clade Ⅰb in the Democratic Republic of the Congo (DRC) in 2024 have highlighted a critical need for improved proactive and response strategies to curb the epidemic.

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Article Synopsis
  • The study investigated how ChatGPT affects creativity and plagiarism in academic writing, gathering data through interviews with researchers from 10 different countries.
  • Results revealed five key themes: opportunities, human assistance, thought-provoking aspects, time-saving benefits, and concerns about negative impacts on writing skills and plagiarism.
  • Researchers suggested that while ChatGPT might change the landscape of creativity and writing, it should be used responsibly with appropriate acknowledgment to avoid issues of plagiarism.
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Developing thermoelectric films without substrates-free-standing films-eliminates substrate-induced effects on performance and meets the flexibility requirements of emerging wearable thermoelectric applications. This study investigates Gallium-doped Zinc Oxide (GZO), composed of abundant and non-toxic elements, to fabricate a substrate-free GZO film via 3D printing and compares its structural, chemical, and thermoelectric properties with those of a substrate-constrained GZO film produced through chemical deposition. Both films exhibited uniform crystal structures and phase purity; however, the substrate-constrained film displayed additional diffraction peaks, suggesting potential substrate interactions.

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To compare the outcomes of rAAV2-ND4 injection in treated versus fellow eyes with Leber's hereditary optic neuropathy (LHON). The protocol was pre-registered on PROSPERO (CRD42023441669). PubMed, Ovid MEDLINE, Cochrane CENTRAL, Google Scholar, Embase, CrossRef, OpenAlex, and Web of Science were reviewed from 1990-2023.

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Article Synopsis
  • Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease affecting synovial joints, often linked to environmental factors and genetics, characterized by both joint and extra-articular symptoms.
  • The review explores the therapeutic potential of natural products in managing arthritis through three methodologies: in-silico analysis identifies molecular targets, in-vivo studies assess safety and effectiveness in reducing inflammation, and in-vitro studies examine cellular interactions and signaling pathways.
  • Overall, the study suggests that natural compounds could serve as valuable adjuncts to traditional RA treatments, highlighting their anti-inflammatory properties and the need for further research to enhance their therapeutic benefits.
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Purpose: The aim of this study was to evaluate quality of life from the preoperative time to six months after surgery of patients who underwent a Shouldice Repair for primary inguinal hernia.

Methods: After ethical approval, consent was obtained, and data collected from surveys and chart review. The study population was composed of male and female patients aged 16-90 years of age, who had a Shouldice Repair of a primary unilateral inguinal hernia.

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Article Synopsis
  • Sepsis is a critical global health issue caused by the body's reaction to infection, significantly impacting patient health and healthcare costs in the U.S.
  • This study presents a new machine learning model that effectively predicts sepsis using diverse datasets from over 40,000 patients, focusing on vital signs and lab results.
  • Results indicated that the combination of stacking ML models with advanced data-splitting techniques improved prediction accuracy, with peaks in F1 scores using COPULA augmentation, outperforming previous methods and underscoring its potential for early sepsis detection in clinical settings.
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D-PRISM: a global survey-based study to assess diagnostic and treatment approaches in pneumonia managed in intensive care.

Crit Care

November 2024

Division of Perioperative, Acute, Critical Care and Emergency Medicine, Department of Medicine, University of Cambridge, Level 4, Addenbrooke's Hospital, Hills Road, Cambridge, UK.

Article Synopsis
  • The D-PRISM study investigated global practices for diagnosing and treating pneumonia in ICU settings, focusing on community-acquired, hospital-acquired, and ventilator-associated pneumonia across different countries.
  • A survey gathered responses from 1,296 ICU clinicians across 72 countries, revealing varied diagnostic processes and a lack of standardized microbiological testing, particularly in lower-income regions.
  • Findings indicated that the typical antibiotic treatment duration was 5-7 days, with shorter durations linked to effective antimicrobial stewardship programs in higher-income countries.
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Comparison of the antibacterial properties of Resin cements with and without the addition of nanoparticles: a systematic review.

BMC Oral Health

November 2024

Department of Oral Medicine & Radiology, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha Dental College, Saveetha University, Chennai, 600077, Tamil Nadu, India.

Article Synopsis
  • Resin cement shows many therapeutic benefits over regular luting materials, but its antibacterial effectiveness is not fully understood.
  • * A literature review was conducted to evaluate the impact of incorporating nanoparticles (NPs) on the antibacterial properties of resin cement, following PRISMA guidelines and reviewing studies from PubMed and Scopus.
  • * Findings revealed that resin cement with NPs significantly lowered bacterial counts and metabolic activity, suggesting potential in reducing secondary caries, but more clinical trials are needed to confirm these benefits.*
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Article Synopsis
  • This study investigates how Gestational Diabetes Mellitus (GDM) is linked to negative pregnancy outcomes, comparing two sets of diagnostic criteria: the IADPSG recommendations and higher cut-off criteria.
  • A systematic review and meta-analysis of 30 observational studies were conducted, focusing on data from 2010 to 2023, using comprehensive databases for sourcing relevant studies.
  • Results showed that GDM significantly increased the likelihood of adverse maternal outcomes like cesarean section (aOR 1.24) and pregnancy-induced hypertension (aOR 1.55), as well as neonatal outcomes like macrosomia (aOR 1.38).
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This scoping review explores mobile health (mHealth) technologies and their features affecting medication adherence in cancer patients. Among 11 selected studies, predominantly from the USA, mHealth tools, particularly smartphone apps, were examined for their features in managing cancer patient's medication adherence. The studies highlighted the importance of adherence in continuous cancer therapy, with mHealth tools offering reminders and interactive features, that aim to enhance patient engagement.

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The application of atificial intelligence (AI) in fundamental physics has faced limitations due to its inherently uninterpretable nature, which is less conducive to solving physical problems where natural phenomena are expressed in human-understandable language, i.e. mathematical equations.

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Background: In Yemen, effective early detection and a comprehensive grasp of breast cancer symptoms and risk factors are vital in preventing its potentially deadly spread. However, challenges arise in combating breast cancer in Yemen due to the lack of patient registries, national strategies, and structured cancer treatment plans.

Objective: This research sought to evaluate the awareness levels of breast cancer and the perceived obstacles to breast cancer screening among adult Yemeni women.

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