25,011 results match your criteria: "Qatar; University of Leicester[Affiliation]"

Foods that support human health and longevity are becoming increasingly relevant as substitutes for or adjuncts to pharmacological drugs, either through direct consumption or incorporation into designer foods fortified with health-promoting ingredients. Date palm (Phoenix dactylifera L.) fruits, seeds, and pollen are a cornerstone of diverse food and medicine traditions.

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Prediction of stroke-associated hospital-acquired pneumonia: Machine learning approach.

J Stroke Cerebrovasc Dis

December 2024

Neurology Section, Neuroscience Institute, Hamad Medical Corporation (HMC), Doha, Qatar. Electronic address:

Article Synopsis
  • Stroke-associated Hospital Acquired Pneumonia (HAP) is a serious concern for stroke patients, and this study investigates using machine learning to predict its occurrence based on national registry data.
  • The research involved analyzing data from nearly 10,000 stroke patients and comparing the performance of various machine learning models, with the Artificial Neural Network (ANN) achieving the best results.
  • Key predictors for HAP were identified through SHAP analysis, indicating that factors like stroke severity and arrival method significantly affect the risk of developing HAP, highlighting the potential for improved patient care through predictive modeling.
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Background: This systematic review evaluates occupational health within the Gulf Cooperation Council (GCC) countries, focusing on ergonomic, physical, chemical, and biological hazards. It identifies significant impacts of these hazards across various professions and underscores the highlights for region-specific strategies and further research.

Methods: A comprehensive search in Scopus, PubMed, and Web of Science databases until October 2023 targeted occupational health studies in the GCC, adhering to PRISMA guidelines and NIH Quality Assessment Tools.

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The role of interleukin 17 in cancer: a systematic review.

Carcinogenesis

January 2025

Department of Basic Medical Sciences, College of Medicine, QU Health, Qatar University, PO Box 2713, Doha, Qatar.

Interleukin 17 (IL17) is a cytokine involved in immune regulation and has been increasingly recognized for its role in cancer progression. This systematic review aims to integrate data on IL17's role in various tumors to better understand its implications for cancer prognosis and treatment. The review included 105 studies (27.

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Background: Peak oxygen consumption (peak O) is traditionally scaled by body mass, but it is most appropriately scaled by fat-free mass. However, it is unknown whether peak O scaled by fat-free mass is associated with mortality and morbidity in people with a Fontan circulation. The aim of this study was to assess the associations between different expressions of peak O with mortality and morbidity in people with a Fontan circulation.

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Purpose: To assess whether corneal nerve analysis can identify and differentiate patients with multiple sclerosis (MS) from those with epilepsy.

Methods: Participants with MS (n = 83), participants with epilepsy (n = 50), and healthy controls (HCs) (n = 20) underwent corneal confocal microscopy (CCM) and quantification of automated corneal nerve fiber length (ACNFL), automated corneal nerve fractal dimension (ACNFrD), and ACNFrD/ACNFL ratio of the subbasal nerve plexus.

Results: ACNFL (MS: P < 0.

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Objectives: The objectives of this study were to analyze trends in prostate cancer incidence, incidence, mortality, and disability-adjusted life years (DALYs) from 1990 to 2021 via data from the Global Burden of Disease (GBD) study in South Asia. Additionally, the study projects future prostate cancer incidence rates up to 2031 to inform public health interventions in South Asia.

Methods: Data covering South Asian countries such as Bangladesh, Bhutan, India, Nepal, and Pakistan were obtained from the GBD 2021 portal.

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Tracking head movement inside an MR scanner using electromagnetic coils.

Heliyon

July 2024

Sir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, Nottingham, NG7 2RD, UK.

Prospective motion corrections in brain imaging for MRI are fairly challenging. Monitoring involuntary head movement inside MR scanner is crucial for prospective motion correction. This initial study delves into utilizing simulations to track the head's movements within an MRI scanner, achieved by measuring induced voltage changes from time-varying magnetic field gradients in head-mounted coils.

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Purpose: Spina bifida (SB) arises from complex genetic interactions that converge to interfere with neural tube closure. Understanding the precise patterns conferring SB risk requires a deep exploration of the genomic networks and molecular pathways that govern neurulation. This study aims to delineate genome-wide regulatory signatures underlying SB pathophysiology.

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In the midst of a vast amount of scientific literature, the need for specific rules arise especially when it comes to deciding which impactful researchers should be nominated. These rules are based on measurable quantities that can easily be applied to a researcher's quantitative data. Various search engines, like Google Scholar, Semantic Scholar, Web of Science etc.

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Giant primary omental cyst: an unusual cause of pseudoascites and hydrocele in a child.

J Surg Case Rep

December 2024

Department of Pediatric Surgery, Hamad Medical Cooperation, Doha 2001, Qatar.

Abdominal lymphangiomas are benign congenital abnormal dilatation and proliferation of lymphatic spaces primarily seen in children. The wide spectrum of symptoms challenges preoperative diagnoses. We present a rare case of a 2-year-old boy presented to pediatrician with massive abdominal distention and left scrotal swelling since the age of 1½ years.

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Metformin has become the frontline treatment in addressing the significant global health challenge of type 2 diabetes due to its proven effectiveness in lowering blood glucose levels. However, the reality is that many patients struggle to achieve their glycemic targets with the medication and the cause behind this variability has not been investigated thoroughly. While genetic factors account for only about a third of this response variability, the potential influence of metabolomics and the gut microbiome on drug efficacy opens new avenues for investigation.

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Background And Aims: We aimed to assess the levels of hepatitis B and C knowledge, attitudes, and practices among medical students in Jordan. A survey included participation from medical students across all faculties in Jordan, from 2022 to 2023.

Methods: The data were analyzed with The R Statistical Software (v4.

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Cell division cycle 6 ​is an independent prognostic biomarker in breast cancer.

Pathology

November 2024

Nottingham Breast Cancer Research Centre, Academic Unit for Translational Medical Sciences, School of Medicine, University of Nottingham Biodiscovery Institute, University Park, Nottingham, UK; Pathology Department, Nottingham University Hospitals NHS Trust, Nottingham, UK; Pathology Department, Hamad Medical Corporation, Doha, Qatar. Electronic address:

Article Synopsis
  • CDC6 is a protein that plays a key role in cell division and cancer cell behavior, and this study examines its impact on breast cancer prognosis using large data sets from various cohorts.
  • High levels of CDC6 are linked to aggressive cancer traits, like larger tumors and negative hormone receptor status, suggesting that it might indicate a poorer patient outcome.
  • The findings support the idea that CDC6 could be a valuable prognostic factor and a potential target for breast cancer therapies, needing more research to explore its functional role.
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Hemodynamic Instability during Squid Embolization of Dural Arteriovenous Fistula: A Case Report.

Neurointervention

December 2024

Department of Neuroradiology, Neuroscience Institute, Hamad Medical Corporation, Hamad General Hospital, Doha, Qatar.

Article Synopsis
  • A case is presented involving a patient with a ruptured paramedian occipital DAVF who experienced sudden sinus bradycardia during embolization while inflating balloons in the occipital arteries.
  • The medical team managed the situation by temporarily stopping the injections and deflating the balloons, allowing for a successful third injection that completely excluded the fistula without further complications.
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Article Synopsis
  • This study presents the first extensive report on Primary Myelofibrosis (PMF) in Qatar, covering data collected over 13 years, as there is a significant lack of information about PMF in the MENA region.
  • Findings show that pre-PMF patients differ from overt PMF patients in terms of blood counts and genetic features, with overt PMF having a higher risk category and worse disease progression.
  • The research provides important insights into the importance of the DIPSS plus scoring system, highlighting its effectiveness in identifying high-risk patients who face worse outcomes and increased treatment needs.
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Ten percent of children with cancer harbour a mutation in a predisposition gene. In children with the kidney cancer, Wilms tumour, the prevalence is as high as 30%. Certain predispositions are associated with defined histological and clinical features, suggesting differences in tumourigenesis.

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Intrathoracic ectopic kidney is an extremely rare congenital defect that is frequently identified by accident because it is asymptomatic. Even more unusual is its link to pulmonary sequestration alone. This case report describes the clinical presentation of a 7-month-old child with a history of recurrent respiratory distress and chest infections since birth, who had shortness of breath, failure to thrive, and delayed developmental milestones.

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Vanadium oxide-based compounds have attracted significant interest as battery materials, especially in aqueous Zn-ion batteries, due to favorable properties and compatibility in Zn-ion systems. In a simple hydrothermal method with moderate conditions, a novel vanadium oxide compound has been synthesized using ammonium metavanadate with oxalic acid as a reducing agent. Various characterization techniques confirmed the formation of layered VO(HO) nanoplatelets with a tetragonal crystal structure.

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Article Synopsis
  • A 48-year-old man experienced dysphagia and a growing neck mass, which was diagnosed as an ectopic thyroid nodule through imaging.
  • The mass was surgically excised, measuring 60×40 mm, and confirmed as a benign, encapsulated ectopic thyroid tissue after histological examination.
  • The patient's recovery was quick, with improved symptoms and normal thyroid function maintained during a 6-month follow-up, highlighting the need for specific imaging and surgical intervention in cases of ectopic thyroid growth.
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  • * A new microwave-assisted spectrofluorimetric technique was developed using environmentally friendly solvents and a fluorescent probe to reduce organic waste, meeting industry validation standards.
  • * The proposed method was found to be user-friendly, cost-effective, and environmentally sustainable, effectively minimizing ecological impact while providing reliable drug analysis.
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  • Traumatic brain injury (TBI) is linked to serious health issues like venous thromboembolism and higher death rates, making early post-traumatic prophylaxis (PTP) important for patient recovery.
  • A systematic review analyzed data from 20 studies with over 87,000 patients, revealing that early PTP significantly cuts the risks of VTE, DVT, PE, and overall mortality compared to later administration.
  • The results emphasize the effectiveness of early pharmacologic thromboprophylaxis in improving outcomes for TBI patients, although the timing of administration (within 48 hours) is particularly critical for achieving statistical significance.
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Introduction: Psoriasis is a systemic inflammatory disease associated with elevated cardiovascular risk due to inflammatory and oxidative stress. Two-dimensional speckle-tracking echocardiography (2D-STE) can detect both regional and global myocardial strain. Impairment of ventricular strain can assist in the early detection of myocardial dysfunction.

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Introduction: Preeclampsia and eclampsia are hypertensive disorders of pregnancy associated with significant maternal and fetal morbidity and mortality. Posterior reversible encephalopathy syndrome (PRES) is a neurological complication observed in these conditions, yet its impact on fetomaternal outcomes remains underexplored. The aim of this study is to investigate the association between PRES and fetomaternal outcomes in women with preeclampsia and eclampsia.

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