Severe Hyperkalemia in a Child with Vomiting and Diarrhea.

Case Presentation: A 13-month-old child with past medical history of congenital adrenal insufficiency presented to the emergency department with vomiting and diarrhea. Initially the child was noticed to have bradycardia with normal blood pressure. An electrocardiogram (ECG) showed tall T waves, broad QRS complex, and widened PR interval suggestive of severe hyperkalemia.

Trends of hip arthroscopy in Italy show an increase over the years: A nationwide study from 2001 to 2016.

Purpose: Hip arthroscopy has gained popularity among orthopaedic procedures over the last decade. The present study aims to evaluate the trends of hip arthroscopy procedures in Italy analysing data recorded by the Italian Ministry of Health, reporting demographics, length of hospitalisation (LOS), diagnosis and the economic impact of the procedure.

Methods: The National Hospital Discharge records reported by the Italian Ministry of Health were used, analysing the data regarding hip arthroscopy procedures performed in Italy between 2001 and 2016.

Clinical attachment loss may serve as a more precise, suitable, and pragmatic grading instrument for periodontitis: A clinical and radiographic validation study.

Objective: The present study was aimed at assessing the sensitivity and accuracy of using clinical attachment loss (CAL) as a substitute tool for grading periodontitis, instead of the interdental bone loss (BL) percentage derived from two-dimensional radiographs.

Methods: One hundred patients diagnosed with periodontitis were included in the study. Periodontitis was graded according to the American Academy of Periodontology (AAP) 2017 classification.

Reporting Clinical Outcomes in Hand Surgery Randomized Controlled Trials: A Systematic Review Using Wide-Awake Local Anesthesia No Tourniquet Studies as a Model.

Purpose: The purpose of this study was to comprehensively evaluate clinical outcome reporting in hand surgery randomized controlled trials (RCTs), using wide-awake local anesthesia no tourniquet (WALANT) studies as a model.

Methods: This International Prospective Register of Systematic Reviews-registered systematic review (CRD42023461653) adheres to preferred reporting items for systematic reviews and meta-analysis guidelines, focusing on RCTs evaluating WALANT in hand and upper limb surgery. A systematic search across five databases was conducted to include all eligible articles from inception until search date (April 1, 2023).

Elevated Risk of Medical and Implant-Related Complications in Patients with Hypothyroidism After Total Shoulder Arthroplasty: A 1:1 Propensity Matched Cohort Analysis.

Background: There is currently limited work that evaluates the effect of co-morbid hypothyroidism on complications and outcomes following total shoulder arthroplasty (TSA). This study aims to evaluate the impact of hypothyroidism on 90-day medical complications as well as 2-year implant related complications and revision rates following TSA.

Methods: This retrospective database analysis evaluated patients who underwent TSA between October 1, 2015, and March 9, 2022.

Plasma volume variations in response to high intensity interval training in obese women: The influential role of menopausal status and age.

Objective: This study aims to explore the effects of high-intensity interval training (HIIT) on plasma volume (PV) variations in obese women, with a focus on understanding how menopausal status and age influence these changes.

Methods: We enrolled fifty-nine obese women (perimenopausal and postmenopausal), aged approximately 56.6 years in a six-week HIIT program.

New world of big data - new challenges for evidence synthesis: Impact of data duplication on estimates generated by meta-analyses, and the development of a framework for its identification and management.

Objective: The aim of this study was to highlight the effects of entering duplicated or overlapping data from published studies using the same data registries into a meta-analysis, including its identification and management using a novel structured framework.

Study Design And Setting: Secondary analysis of data from a proportional meta-analysis of 30-day cumulative incidence of venous thromboembolic events (VTE) after metabolic and bariatric surgery was performed. Sensitivity analysis was conducted a) including all studies regardless of duplication (uncorrected sample) and b) comparing it to a corrected sample of studies.

Amygdalin in antineoplastic medicine and the relevance of nanotechnology.

Amygdalin is a plant-based cyanogenic glycoside that has been the subject of both scientific interest and controversy for decades. Traditionally used in alternative medicine for its diverse biological activities, including anticancer, where amygdalin has been explored in complementary therapy. However, clinical utilization of amygdalin remains contentious due to concerns about its safety, primarily the release of hydrogen cyanide during its metabolism.

Efficacy and safety of ensifentrine, a novel phosphodiesterase 3 and 4 inhibitor, in chronic obstructive pulmonary disease: A systematic review and meta-analysis.

Background: We evaluated the efficacy and safety of Ensifentrine in COPD via a systematic review and meta-analysis of randomized controlled trials (RCTs).

Methods: We performed a detailed literature search on Medline (via PubMed), Scopus, Google Scholar, and Cochrane on the basis of pre-specified eligibility criteria. We used Review Manager to calculate pooled mean differences (MD) and 95% Confidence Interval (CI) using a random effects model.

Cultural & region-specific adaptation of KAP (Knowledge, attitude, and practice) tool to capture healthy lifestyle within primary care settings.

Background: Non-communicable diseases contribute to a significant global burden of disease and are associated with modifiable risk factors such as physical inactivity, unhealthy diet, tobacco use and excessive alcohol consumption. These risk factors are closely related with lifestyles and eating patterns which are often culturally embedded and managed differently in various health care settings.

Aim Of The Study: To assesses the applicability and feasibility of the KAPS (Knowledge, attitude, and practice) survey in generating data about knowledge, attitudes, and practices about healthy lifestyles within eastern Mediterranean settings and providing foundations for testing other models or development of a newer model in this area which captures and influence behavior changes towards healthy lifestyles.

Addiction to smartphones in Arabs is associated with severe depressive symptoms and insomnia: a cross-sectional study.

Addiction to smartphones is a global issue. Mental health disturbance is an emerging factor implicated in smartphone addiction. Whether depressive symptoms and anxiety are implicated in smartphone addiction in developing countries such as Jordan is a nexus that warrants investigation.

Reviving the Critically Ill: Exploring Effective Fluid Resuscitation Approaches for Diverse Hypovolemic Shock Cases-A Systematic Review and Meta-Analysis.

Objective: The present study was performed to investigate the efficacy of different resuscitation fluids in critically ill patients presenting any type of hypovolemic shock.

Methods: We comprehensively searched PubMed, Web of Science, ScienceDirect, Cochrane Library, and Google Scholar for randomized trials published in English from January 1990 to August 2023. The risk of bias and methodological quality assessment was performed using Cochrane's risk of bias tool embedded within the Review Manager software (RevMan 5.

COVID-19 Increases the Risk of New Myocardial Infarction in Patients with Old Myocardial Infarction: A Retrospective Observational Study.

Background: We aimed to investigate the incidence of new acute myocardial infarction (AMI), in patients with Coronavirus disease (COVID-19) who had old MI. We hypothesized that COVID-19 increases the rate of repeated AMI in this population regardless of age and gender.

Methods: A retrospective analysis was conducted for adult patients admitted with COVID-19 and developed thromboembolic event (TEE) in 2020.

Incidental finding of hepatic pseudolesion from aberrant right gastric vein in a breast cancer patient.

Aberrant right gastric veins (ARGV) represent rare anatomical variations that can result in hepatic pseudolesions, mimicking malignancies due to their atypical drainage directly into the liver parenchyma. This case highlights a 44-year-old woman initially presenting with a breast mass incidentally found to have an ARGV-related pseudolesion in hepatic segment IVa. ARGV is clinically significant as it can alter hepatic blood flow dynamics, leading to hyperdense or hypodense regions on imaging.

Covered Stent Correction for Sinus Venosus Atrial Septal Defects, an Emerging Alternative to Surgical Repair: Results of an International Registry.

Background: Covered stent correction for a sinus venosus atrial septal defect (SVASD) was first performed in 2009. This innovative approach was initially viewed as experimental and was reserved for highly selected patients with unusual anatomic variants. In 2016, increasing numbers of procedures began to be performed, and in several centers, it is now offered as a standard of care option alongside surgical repair.

A survey of quit vaping strategies and relapse triggers for maintaining youth and young adult vaping abstinence in Canada.

Objectives: To examine whether various quit strategies and relapse triggers are associated with maintenance period in a sample of people who quit vaping.

Method: Young Canadians who used to vape ( = 772) completed an online survey on maintenance period, quit strategies, and relapse triggers. Logistic regression was employed to variables associated with maintenance period.

Effect of statins on arterial wall inflammation as assessed by 18F-FDG PET CT: an updated systematic review and meta-analysis.

Background: Pathogenesis of atherosclerosis is largely mediated by inflammatory process. Statins are lipid-lowering drugs which also have anti-inflammatory effects. 18 fluorine radiolabeled fluorodeoxyglucose (18 F-FDG) positron emission tomography-computed tomography (PET-CT) is considered to be a good indicator of arterial wall inflammation.

The burden and clinical trajectory of immune checkpoint inhibitor-induced endocrinopathies: an 8-year experience.

Background: Immune checkpoint inhibitors (ICIs) have revolutionized the management of cancer patients, but the emergence of ICI-related endocrinopathies (IREs) has introduced new clinical challenges. Despite worldwide recognition of these adverse effects, data from the Middle East is scarce.

Methods: This retrospective-observational study included adult cancer patients who received at least one dose of ICI between January 2015 and January 2023.

Psychological stress among hypertensive male patients in Jordan: prevalence and associated factors.

Background: Hypertension is a global, modifiable risk factor for cardiovascular and cerebrovascular disorders, imposing a significant burden due to its high mortality and morbidity rates. This study aimed to assess the prevalence and severity of psychological stress among hypertensive patients in Jordan and identify the factors associated with psychological stress.

Methods: This descriptive, cross-sectional study was conducted on hypertensive patients at three community healthcare clinics in Jordan from May to July 2024.

Health and Well-Being in the Context of Health-Promoting University Initiatives: Protocol for a Mixed Methods Needs Assessment Study at Qatar University.

Background: Health-promoting universities are dedicated to fostering learning environments and organizational cultures that support the physical and mental well-being of students, faculty, and staff. As students constitute the largest group within the university community, any policy intervention targeting them is likely to have a significant impact on the university as a whole.

Objective: This study aims to assess the health status and needs of Qatar University (QU) students using a comprehensive and holistic definition of health, informed by the perspectives of students, faculty members, and key informants.

Effect of DOPA decarboxylase inhibitor supplements on the incidence of urinary tract infections in Parkinson's disease patients: A systematic review and meta-analysis of randomized controlled trials.

Objectives: Parkinson's disease is the most common neurodegenerative disease. Combining levodopa with other drugs, including decarboxylase inhibitors (DCI) is its most effective treatment. Urinary tract infection (UTI) is the most common cause of hospitalization in Parkinson's patients, making it crucial to find an appropriate treatment to reduce the incidence of this complication.

Electrified Enhanced Recovery of Lithium from Unconventional Sources.

Demand for lithium is expected to quadruple by the end of the decade. Without new sources of production, the supply-demand curve is expected to invert. Traditional geological reserves will not be able to meet the anticipated gap, thus unconventional sources of lithium will need to be utilized, setting the stage for fierce competition for perhaps the most critical of mineral resources required for the energy transition.

The current physical activity in persons with disability in Qatar: a cross-sectional study.

Purpose: The primary objective of this study was to measure and quantify the current level of physical activity among persons with disability in Qatar. The secondary objective was to assess and analyze the duration of sedentary behavior among individuals with disability in Qatar.

Methods: This was a cross-sectional epidemiological study of persons with disability living in Qatar.