2 results match your criteria: "Q2:09 Astrid Lindgren Children's Hospital[Affiliation]"
Lead induces increased water permeability in astrocytes expressing aquaporin 4.
Neuroscience
February 2006
Nordic Centre for Water Imbalance Related Disorders, Department of Woman and Child Health, Karolinska Institutet, Pediatric Unit, Research Laboratory, Q2:09 Astrid Lindgren Children's Hospital, 171 76 Stockholm, Sweden.
The water channel aquaporin 4 (AQP4) is abundantly expressed in astrocytes. There is now compelling evidence that AQP4 may contribute to an unfavorable course in brain edema. Acute lead intoxication is a condition that causes brain damage preceded by brain edema.
View Article and Find Full Text PDFOsmotic water permeability measurements using confocal laser scanning microscopy.
Eur Biophys J
January 2001
Department of Woman and Child Health, Q2: 09 Astrid Lindgren Children's Hospital, Karolinska Institutet, Stockholm, Sweden.
We have developed a method for measurement of plasma membrane water permeability (P(f)) in intact cells using laser scanning confocal microscopy. The method is based on confocal recording of the fluorescence intensity emitted by calcein-loaded adherent cells during osmotic shock. P(f) is calculated as a function of the time constant in the fluorescence intensity change, the cell surface-to-volume ratio and the fractional content of the osmotically active cell volume.
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