142 results match your criteria: "Pyoderma Vegetans"

Pyodermatitis pyostomatitis vegetans is a rare variant of neutrophilic disorders, affecting the intertriginous areas such as axilla and groin, umbilicus, as well as the oral mucosa. We herein describe 2 female patients, in both of whom the umbilicus was restrictedly involved.

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Doxycycline monotherapy for pyoderma vegetans: a case report.

J Dermatolog Treat

December 2024

Department of Dermatology, Mohamed V University of Rabat, Ibn Sina University Hospital, Rabat, Morocco.

Article Synopsis
  • Pyoderma vegetans (PV) is a rare skin condition characterized by neutrophilic inflammation, and its cause is not well understood.
  • There are currently no official treatment guidelines for PV, with systemic steroids typically being the initial treatment option, but they often lead to recurrences when stopped.
  • A study tested doxycycline at a dosage of 200 mg per day for four weeks, showing significant improvement in PV symptoms, suggesting it may be a useful alternative that reduces the reliance on systemic steroids.
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  • Pyodermatitis-pyostomatitis vegetans (PPV) is a rare disease indicated by pustules that often signals inflammatory bowel disease (IBD), with oral manifestations known as pyostomatitis vegetans (PSV).
  • A study analyzed various cases of PSV from literature to identify key diagnostic features, including specific appearances of oral lesions and their relation to IBD.
  • The research found 77 PSV cases with helpful diagnosis indicators but noted the lack of a standardized treatment approach, which typically involves multiple medications like corticosteroids and immunosuppressives, and highlighted a high risk of oral lesion recurrence upon dosage changes.
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  • The study examines the effectiveness of lasers in treating inflammatory dermatoses and connective tissue disorders, noting that previous evidence on this topic is limited.
  • A retrospective review of 60 cases treated at a laser clinic from 2010 to 2020 shows that 62% of patients experienced significant improvement, mainly with pulsed dye lasers, while some faced side effects like purpura.
  • Despite the study's findings suggesting lasers can help manage challenging skin conditions, it acknowledges limitations due to a lack of objective measures for assessing outcomes.
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Article Synopsis
  • Pyodermatitis pyostomatitis vegetans is a rare inflammatory condition affecting the skin and/or mucous membranes, with lesions commonly appearing on the scalp, face, trunk, and extremities, as well as in oral mucosa.
  • The clinical presentation includes erosive granulomatous plaques, keratotic plaques, and pustular lesions, with some lesions displaying a distinctive 'snail track' appearance.
  • Unique histopathological features include epidermal hyperplasia and eosinophilic microabscesses, while activated neutrophils and eosinophil extracellular traps may play a role in its pathogenesis and inflammatory response.
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  • Biologics are used in dermatology to treat inflammatory skin diseases like atopic dermatitis and psoriasis by blocking certain signaling pathways associated with inflammation.
  • These treatments have been effective and generally safe, but they can sometimes disrupt the immune system's balance.
  • The study discusses a patient who developed a worsening of pemphigus foliaceus after using secukinumab, a biologic drug, for other skin conditions.
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Article Synopsis
  • Two patients who use cocaine showed unusual lesions in their mouths.
  • Biopsy and immunofluorescence tests confirmed these lesions are related to a condition called pyostomatitis vegetans-pyodermatitis vegetans.
  • This highlights a potential link between cocaine use and these specific oral health issues.
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  • Pyodermatitis-pyostomatitis vegetans (PD-PSV) is a rare skin condition in kids, and this text reviews existing literature on it.
  • The case discussed involves a 15-year-old boy who developed widespread PD-PSV without any prior inflammatory bowel disease or gastrointestinal issues.
  • Treatment with infliximab effectively cleared the skin lesions and uncovered underlying subclinical Crohn's disease.
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Dermatological Manifestations in Inflammatory Bowel Diseases.

J Clin Med

January 2021

Gastroenterology Unit, Department of Biomedical and Clinical Sciences, "L.Sacco" Hospital, 20157 Milano, Italy.

Article Synopsis
  • * The review identifies several types of dermatologic issues linked to IBD, including specific manifestations unique to Crohn's disease, common skin disorders, reactive conditions, and issues arising from treatments.
  • * An important takeaway is that thorough dermatological evaluations are crucial for IBD patients, particularly those undergoing biologic therapies, to address potential drug-induced skin reactions effectively.
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  • Pyoderma vegetans (PV) is a rare skin condition linked to ulcerative colitis (UC), especially when it affects the nasal mucosa.
  • A 28-year-old woman with UC and a history of pyoderma gangrenosum experienced nasal pain, leading to a diagnosis of PV through histopathological examination.
  • After treatment with oral prednisone, she responded well and remained symptom-free after a year, highlighting the need for further investigation in UC patients with nasal issues.
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  • Inflammatory bowel disease (IBD) is increasingly common in children and can cause various skin issues that complicate treatment for pediatric gastroenterologists.
  • This literature review analyzed articles from 2005 to present, focusing on the types of dermatological manifestations associated with IBD in kids, their correlation with disease activity, and demographic factors.
  • Common skin issues related to pediatric IBD include erythema nodosum and pyoderma gangrenosum, while treatments like anti-TNF agents can lead to skin infections and other complications.
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  • Pyodermatitis-pyostomatitis vegetans is a rare skin condition linked closely to inflammatory bowel diseases like ulcerative colitis.
  • A case study is presented alongside a review of literature from the past 18 years, highlighting the disease's characteristics, connections, and immunofluorescence findings.
  • Out of 38 cases reviewed (22 men and 16 women, average age 40), 32 underwent direct immunofluorescence staining, with 12 showing positive results, indicating a potential relationship with autoimmune diseases.
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Pyostomatitis vegetans (PV) is a rare inflammatory stomatitis often associated with inflammatory bowel diseases (IBD). Treatment of PV depends on the presence of coexisting IBD. To date, there have been no reports on the use of ustekinumab for PV.

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  • Necrobiosis lipoidica (NL) is an inflammatory skin disease linked to diabetes mellitus, presenting as red-brown papules that form plaques on the lower legs.
  • Diagnosis is primarily clinical, but a biopsy can confirm NL.
  • If not treated, NL may ulcerate, leading to additional complications, though it doesn't progress to pyoderma vegetans (PV).
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