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Background And Aim: Foot-and-mouth disease (FMD) is a highly contagious viral disease that endangers livestock and the environment with significant economic consequences. This study aimed to validate the inactivation of the Indonesian isolate of foot-and-mouth disease virus (FMDV) with various formaldehyde concentration.

Materials And Methods: The experiment started with FMDV being adapted on BHK-21 cells until cytopathic effects (CPE) appeared.

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