3,979 results match your criteria: "Pukyong National University[Affiliation]"
J Control Release
December 2024
Major of Human Bio-convergence, Division of Smart Healthcare, Pukyong National University, Busan 48513, Republic of Korea. Electronic address:
Inflammatory bowel disease (IBD) is a chronic or recurrent inflammatory disorder affecting various parts of the gastrointestinal tract. Metformin, a widely prescribed hypoglycemic drug for type 2 diabetes, has shown potential in reducing IBD risk. However, its oral administration faces significant challenges due to the harsh gastrointestinal environment, requiring higher or more frequent doses to achieve therapeutic effects, which increases the risk of side effects.
View Article and Find Full Text PDFInt J Biol Macromol
December 2024
Marine Integrated Biomedical Technology Center, The National Key Research Institutes in Universities, Pukyong National University, Busan, Republic of Korea; Industry 4.0 Convergence Bionics Engineering, Pukyong National University, Busan, Republic of Korea; Major of Biomedical Engineering, Division of Smart Healthcare, College of Information, Pukyong National University, Busan, Republic of Korea. Electronic address:
Conventional treatment of prostate cancer need more specificity, and higher efficiency. The present work is the first attempt to utilize hydrogel-loaded carvacrol-based chemotherapy with fractionated photothermal therapy (F-PTT) using a 635 nm laser for its treatment. Gold nanobipyramids (AuNBPs) were used as drug carrier and photosensitizer.
View Article and Find Full Text PDFJ Fish Dis
December 2024
Department of Aquatic Life Medicine, Pukyong National University, Busan, Republic of Korea.
Red sea bream iridovirus (RSIV) occurs mainly at high water temperatures and infects more than 30 different species of fish. In Asia, infected fish cause mass mortality every year. Molecular diagnostics is a technology that efficiently detects and identifies a wide range of fish pathogens through rapid and sensitive analysis of their genetic material.
View Article and Find Full Text PDFAnim Microbiome
December 2024
Department of Aquatic Life Medicine, Pukyong National University, Busan, Republic of Korea.
Background: In aquaculture, the secretions of cultured organisms contribute to the development of aquatic antibiotic resistance. However, the antibiotic-induced changes in fish feces remain poorly understood. This study aimed to assess the short-term dynamics of fecal microbiome and antibiotic resistance in juvenile rainbow trout (Oncorhynchus mykiss) upon antibiotic treatment and withdrawal period.
View Article and Find Full Text PDFSci Adv
December 2024
Department of Materials Science and Engineering, Seoul National University, Seoul 08826, Republic of Korea.
Real-time monitoring of infinitesimal deformations on complex morphologies is essential for precision biomechanical engineering. While flexible strain sensors facilitate real-time monitoring with shape-adaptive properties, their sensitivity is generally lower than spectroscopic imaging methods. Crack-based strain sensors achieve enhanced sensitivity with gauge factors (GFs) exceeding 30,000; however, such GFs are only attainable at large strains exceeding several percent and decline below 10 for strains under 10, rendering them inadequate for minute deformations.
View Article and Find Full Text PDFACS Nano
December 2024
Department of Chemical and Biomolecular Engineering, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States.
Despite the numerous advantages demonstrated by microfluidic mixing for RNA-loaded lipid nanoparticle (RNA-LNP) production over bulk methods, such as precise size control, homogeneous distributions, higher encapsulation efficiencies, and improved reproducibility, their translation from research to commercial manufacturing remains elusive. A persistent challenge hindering the adoption of microfluidics for LNP production is the fouling of device surfaces during prolonged operation, which significantly diminishes performance and reliability. The complexity of LNP constituents, including lipids, cholesterol, RNA, and solvent mixtures, makes it difficult to find a single coating that can prevent fouling.
View Article and Find Full Text PDFSci Data
December 2024
Division of Life Sciences, Korea Polar Research Institute, Incheon, 21990, Republic of Korea.
The Arctic Ocean is experiencing significant global warming, leading to reduced sea-ice cover, submarine permafrost thawing, and increased river discharge. The East Siberian Sea (ESS) undergoes more significant terrestrial inflow from coastal erosion and river runoff than other Arctic seas. Despite extensive research on environmental changes, microbial communities and their functions in the ESS, which are closely related to environmental conditions, remain largely unexplored.
View Article and Find Full Text PDFAdv Sci (Weinh)
December 2024
Department of Materials Science and Engineering, Seoul National University, Seoul, 08826, Republic of Korea.
Bioinspired sensory systems based on spike neural networks have received considerable attention in resolving high energy consumption and limited bandwidth in current sensory systems. To efficiently produce spike signals upon exposure to external stimuli, compact neuron devices are required for signal detection and their encoding into spikes in a single device. Herein, it is demonstrated that Mott oscillative spike neurons can integrate sensing and ceaseless spike generation in a compact form, which emulates the process of evoking photothermal sensing in the features of biological photothermal nociceptors.
View Article and Find Full Text PDFPhys Rev E
November 2024
Department of Scientific Computing, Pukyong National University, Busan 48513, Korea.
Heider's balance theory emphasizes cognitive consistency in assessing others, as expressed by the phrase "The enemy of my enemy is my friend." At the same time, the theory of indirect reciprocity provides us with a dynamical framework to study how to assess others based on their actions as well as how to act toward them based on the assessments. Well known are the "leading eight" from L1 to L8, the eight norms for assessment and action to foster cooperation in social dilemmas while resisting the invasion of mutant norms prescribing alternative actions.
View Article and Find Full Text PDFNanoscale
December 2024
Regional Leading Research Center for Smart Energy System, Kyungpook National University, Daegu 41566, Korea.
As a leading Pb-free perovskite material (ABO-type), potassium sodium niobate (K,Na)NbO (KNN)-based ferroelectrics/piezoelectrics have been widely used in electronics, energy conversion, and storage due to their exceptional ability to interconvert mechanical and electrical energies. Beyond traditional applications, the piezoelectric potential generated by mechanical strain or stress modifies their energy band structures and facilitates charge carrier separation and transport, drawing increasing attention in emerging fields such as piezocatalysis and photo-piezocatalysis. With excellent piezoelectric properties, chemical/thermal stability, and strain-tuning capability, KNN-based materials show great promise for high-performance piezocatalytic applications.
View Article and Find Full Text PDFSensors (Basel)
December 2024
Department of Environmental Engineering, Pukyong National University, Busan 48513, Republic of Korea.
Rapid industrialization and the influx of human resources have led to the establishment of industrial complexes near urban areas, exposing residents to various air pollutants. This has led to a decline in air quality, impacting neighboring residential areas adversely, which highlights the urgent need to monitor air pollution in these areas. Recent advancements in technology, such as Solar Occultation Flux (SOF) and Sky Differential Optical Absorption Spectroscopy (SkyDOAS) used as remote sensing techniques and mobile extraction Fourier Transform Infrared Spectrometry (MeFTIR) used as an in situ technique, now offer enhanced precision in estimating the pollutant emission flux and identifying primary sources.
View Article and Find Full Text PDFJ Clin Med
November 2024
School of Life Science and Biotechnology, BK21 FOUR KNU Creative BioResearch Group, Kyungpook National University, Daegu 41566, Republic of Korea.
Parkinson's disease (PD) is a neurodegenerative disorder characterized by both motor symptoms and non-motor features. A hallmark of PD is the misfolding and accumulation of alpha-synuclein (α-syn), which triggers neuroinflammation and drives neurodegeneration. Microglia, brain cells that play a central role in neuroinflammatory responses and help clear various unnecessary molecules within the brain, thus maintaining the brain's internal environment, respond to α-syn through mechanisms involving inflammation, propagation, and clearance.
View Article and Find Full Text PDFMaterials (Basel)
November 2024
Semiconductor Materials Center, Korea Institute of Ceramic Engineering and Technology (KICET), Jinju 52851, Republic of Korea.
A recent study reported the rapid growth of SiC single crystals of ~1.5 mm/h using high-purity SiC sources obtained by recycling CVD-SiC blocks used as materials in semiconductor processes. This method has gained attention as a way to improve the productivity of the physical vapor transport (PVT) method, widely used for manufacturing single crystal substrates for power semiconductors.
View Article and Find Full Text PDFMolecules
November 2024
Department of Chemistry and Nanoscience, Ewha Womans University, Seoul 03760, Republic of Korea.
Three new depsipeptides, homiamides A-C (-), were isolated from a marine sediment-derived strain of sp., ROA-065. The planar structures of homiamides A-C (-) were elucidated using mass spectrometry (MS) and nuclear magnetic resonance (NMR) spectroscopic data.
View Article and Find Full Text PDFBiomed Opt Express
December 2024
Industry 4.0 Convergence Bionics Engineering and Marine-integrated Biomedical Technology Center, Pukyong National University, Busan, Republic of Korea.
Interstitial laser treatment (ILT) using a diffusing applicator (DA) has been employed to treat tumors. However, the treatment efficacy and safety of the emission profiles from DAs have been poorly explored. This study investigated the effect of the emission profiles from DAs on prostate tumor treatment.
View Article and Find Full Text PDFCytotechnology
February 2025
Department of Fisheries Biology, Pukyong National University, Busan, 48513 Korea.
Culturing fish myogenic cells in vitro holds significant potential to revolutionize aquaculture practices and support sustainable food production. However, advancement in in vitro culture technologies for skeletal muscle-derived myogenic cells have predominantly focused on mammals, with limited studies on fish. Scaffold-based three-dimensional (3D) culture systems for fish myogenic cells remain underexplored, highlighting a critical research gap compared to mammalian systems.
View Article and Find Full Text PDFTissue Cell
December 2024
Major of Human Bio-convergence, Division of Smart Healthcare, Pukyong National University, Busan 48513, Republic of Korea. Electronic address:
Myricetin, a flavonoid present in numerous fruits, vegetables, and medicinal plants, is recognized for its potent antioxidant, anti-inflammatory, and anti-cancer activities. Nevertheless, its involvement in mitigating inflammation caused by the endocrine-disrupting chemical Di(2-ethylhexyl) phthalate (DEHP), commonly used in polyvinyl chloride (PVC) manufacturing to improve flexibility, has not been investigated. Here, we found that DEHP markedly increased IL-1β production through inflammatory pathways in RAW 264.
View Article and Find Full Text PDFEnviron Toxicol Pharmacol
December 2024
Department of Marine Life Science, Jeju National University, Jeju 63243, Republic of Korea; Department of Aquatic Life Medicine, Jeju National University, Jeju 63243, Republic of Korea. Electronic address:
Starry flounders (Platichthys stellatus, mean weight 105 ± 14 g, mean total length 20.2 ± 0.7 cm) were exposed to hexavalent chromium concentrations of 0, 5, 10, 20, 40, and 80 mg Cr/L for 96 hours.
View Article and Find Full Text PDFComput Biol Med
December 2024
Department of Biotechnology, School of Applied Sciences, REVA University, Rukmini Knowledge Park, Bangalore 560064, India; School of Biosciences, Taylor's University, Lakeside Campus, 47500, Subang Jaya, Selangor, Malaysia; Faculty of Earth Sciences, Universiti Malaysia Kelantan, Campus Jeli, Kelantan, 17600 Jeli, Malaysia. Electronic address:
Early diagnosis and timely initiation of treatment plans for diabetes are crucial for ensuring individuals' well-being. Emerging technologies like artificial intelligence (AI) and computer vision are highly regarded for their ability to enhance the accessibility of large datasets for dynamic training and deliver efficient real-time intelligent technologies and predictable models. The application of AI and computer vision techniques to enhance the analysis of clinical data is referred to as eHealth solutions that employ advanced approaches to aid medical applications.
View Article and Find Full Text PDFJ Voice
December 2024
Digital Healthcare Research Center, Pukyong National University, Busan 48513, Republic of Korea; Division of Smart Healthcare, College of Information Technology and Convergence, Pukyong National University, Busan 48513, Republic of Korea; Department of Industry 4.0 Convergence Bionics Engineering, Pukyoung National University, Busan 48513, Republic of Korea. Electronic address:
Parkinson's disease (PD) is a neurodegenerative disorder affecting motor and non-motor functions, including speech. This study evaluates the effectiveness of the audio spectrogram transformer (AST) model in detecting PD through vocal biomarkers, hypothesizing that its self-attention mechanism would better capture PD related speech impairments compared to traditional deep learning approaches. Speech recordings from 150 participants (100 from PC-GITA: 50 PD, 50 healthy controls (HC); 50 from Italian Parkinson's voice and speech (ITA): 28 PD, 22 HC) were analyzed using the AST model and compared against established architectures including VGG16, VGG19, ResNet18, ResNet34, vision transformer, and swin transformer.
View Article and Find Full Text PDFHarmful Algae
January 2025
Third Institute of Oceanography, Ministry of Natural Resources, Xiamen 361005, China. Electronic address:
Yessotoxin is one of the shellfish toxins leading to mussel farm closures in the Adriatic Sea of Italy. Two putative Gonyaulax spinifera strains GSA0501 and GSA0602 are known as yessotoxins producers, but their identities have remained elusive since 2005. To address this gap, we established five Gonyaulax strains by incubating sediments from the Adriatic Sea and subsequently isolating single cells.
View Article and Find Full Text PDFBiomacromolecules
December 2024
Department of Chemistry, Yonsei University, Seoul 03722, Republic of Korea.
Herein, we present a significant advancement in long-term cryopreservation techniques for microalgae species using a combination of linear polyglycerol (PG) and dimethyl sulfoxide (DMSO). The technique was tested on three species: , , and , which showed long-term viability and recovery rates superior to those when treated with a traditional cryoprotectant only. While DMSO alone enabled high cell recovery rates for all species after 1 week of cryopreservation, the rates for some of them dropped below 50% after 26 weeks of cryopreservation.
View Article and Find Full Text PDFAnalyst
December 2024
Anastro Laboratory, Institute of Basic Science, Changwon National University, Changwon 51140, Republic of Korea.
Dipicolinic acid (DPA) is a key biomarker of bacterial spores. In this study, we present a novel distance-based paper analytical device (d-PAD) for the fluorescence sensing of DPA. The detection mechanism relies on the complexation of ofloxacin (OFL) with Cu ions, where Cu quenches the fluorescence of OFL static quenching.
View Article and Find Full Text PDFEnviron Sci Pollut Res Int
December 2024
Graduate School of Management of Technology, Pukyong National University, Nam-Gu, Busan, Republic of Korea.
Int J Biol Macromol
December 2024
Research Center for Marine-Integrated Bionics Technology, Pukyong National University, Busan 48513, Republic of Korea; Major of Biomedical Engineering, Division of Smart Healthcare, College of Information Technology and Convergence and New-senior Healthcare Innovation Center (BK21 Plus), Pukyong National University, Busan 48513, Republic of Korea; Marine integrated Biomedical Technology center, The National Key Research Institutes in Universities, Pukyong National University, Busan 48513, Republic of Korea. Electronic address: