Effect and individual response to inspiratory muscle training program among instrumentalist musicians.

In this quasi-experimental before-after trial, we investigated the effects of a high-intensity, low-repetition inspiratory muscle training (HI-LRMT) protocol on respiratory muscle strength in instrumental musicians. In addition, was to estimate the prevalence of "non-responders" (NRs) in terms of muscle force after intervention. Healthy musicians ( = 48) were divided into 2 groups: HI-LRMT ( = 33) and a control group that did not train (CG, = 15).

Spatiotemporal Symmetries and Energy-Momentum Conservation in Uniform Spacetime Metamaterials.

Spacetime metamaterials are opening new regimes of light-matter interactions based on the breaking of temporal and spatial symmetries, as well as intriguing concepts associated with synthetic motion. In this work, we investigate the continuous spatiotemporal translation symmetry of spacetime metamaterials with uniform modulation velocity. Using Noether's theorem, we demonstrate that such symmetry entails the conservation of the energy momentum.

A Novel Class of FKBP12 Ligands Rescues Premature Aging Phenotypes Associated with Myotonic Dystrophy Type 1.

Myotonic dystrophy type 1 (DM1) is an autosomal dominant disorder clinically characterized by progressive muscular weakness and multisystem degeneration, which correlates with the size of CTG expansion and MBLN decrease. These changes induce a calcium and redox homeostasis imbalance in several models that recapitulate the features of premature tissue aging. In this study, we characterized the impact of a new family of FKBP12 ligands (generically named MPs or MP compounds) designed to stabilize FKBP12 binding to the ryanodine receptors and normalize calcium dysregulation under oxidative stress.

Behavioral coping with chronic defeat stress in mice: A systematic review of current protocols.

Social stress is the most significant source of chronic stress in humans and is commonly associated with health impairment. Individual differences in the behavioral coping responses to stress have been proposed to mediate the negative effects of stress on physical, behavioral and mental health. Animal models, particularly mice, offer valuable insights into the physiological and neurobiological correlates of behavioral coping strategies in response to chronic social stress.

Effects of an individualised exercise program in hospitalised older adults with cancer: A randomised clinical trial.

We aimed to examine the effects of an individualised multicomponent exercise program on functional outcomes in hospitalised older patients with cancer. Patients aged ≥ 65 were recruited upon admission to a Medical Oncology Department and randomly allocated to receive a multicomponent exercise training program twice daily for five days or standard hospital care. The primary outcome measure was the change in functional status using the Short Physical Performance Battery.

New horizons in hospital-associated deconditioning: a global condition of body and mind.

Hospital-associated deconditioning is a broad term, which refers non-specifically to declines in any function of the body secondary to hospitalisation. Older people, particularly those living with frailty, are known to be at greatest risk. It has historically been most commonly used as a term to describe declines in muscle mass and function (i.

A Novel -Based Nanofertilizer Promotes Seedling Growth and Vigor in Wheat ( L.).

Excessive use of chemical fertilizers poses significant environmental and health concerns. Microbial-based biofertilizers are increasingly being promoted as safe alternatives. However, they have limitations such as gaining farmers' trust, the need for technical expertise, and the variable performance of microbes in the field.

Blood pressure targets for hypertension in people with chronic renal disease.

Background: Chronic kidney disease (CKD) is an independent risk factor for cardiovascular disease, development of end-stage renal disease, and all-cause mortality. It affects around 10% of the population worldwide. The prevalence of hypertension in people with CKD ranges from 22% in stage 1 to 80% in stage 4.

Navigating the Challenges and Resilience in the Aftermath of the COVID-19 Pandemic in Adolescents with Chronic Diseases: A Scoping Review.

Background/objectives: The COVID-19 pandemic has profoundly affected the lives of adolescents worldwide, especially those living with chronic diseases. This study aims to explore the impact of the COVID-19 pandemic on the daily lives of adolescents with chronic diseases.

Methods: This is a scoping review that follows the guidelines proposed by JBI.

Challenges of Creating a Peer Support Online Community for Patients With Diabetes-A Case Study.

This study aims to explore the challenges and strategies in creating online communities for individuals with diabetes, emphasizing their role in fostering connections among individuals facing similar health conditions. Using a single-case approach, we investigated the design process of a diabetes online community using the classic waterfall model. Participants were recruited from a diabetes local association, and usability was assessed using the System Usability Scale and the think-aloud method.

A bottom-up framework for nurses' protocol-based care decision-making.

Aim: To develop a conceptual framework for nurses' protocol-based care decision-making.

Design: Miles & Huberman's bottom-up approach to developing conceptual frameworks was followed, using data collected from a multiple embedded case study examining protocol-based decision-making by nurses in three hospital wards within a university hospital in northern Spain.

Methods: The qualitative data from the case study, obtained through documentary analysis, observations, and interviews, underwent a secondary analysis consisting of four steps: data reduction, data display, comparison, and drawing conclusions.

Postoperative physical rehabilitation in the elderly patient after emergency surgery. Influence on functional, cognitive and quality of live recovery: study protocol for a randomized clinical trial.

Background: The progressive aging of the population has meant the increase in elderly patients requiring an urgent surgery. Older adults, especially those with frailty, have a higher risk for complications, functional and cognitive decline after urgent surgery. These patients have their functional and physiological reserve reduced which makes them more vulnerable to the effects of being bedridden.

[Analysis of serious trauma injury patterns in Navarre (Spain) (2010-2019)].

Background: The aim of this study is to describe major trauma cases in Navarre and analyze differences based on mortality groups, sex, and mode of injury.

Methods: Cross-sectional study of major traumas (severity =3) registered in Navarre between 2010 and 2019. We analyzed the type of trauma, intentionality, the mode of injury, and the affected anatomical area.

Virtual Reality to Reduce Pain, Fatigue, and Emotional Distress in People With Cancer: A Scoping Review.

Background: Cancer and its treatments cause symptoms such as pain, fatigue, and emotional distress, which affect the quality of life of patients at different stages of cancer. Virtual reality (VR) has emerged as a promising alternative for addressing these symptoms by immersing patients in a virtual environment that isolates them from reality.

Objective: To describe the existing evidence on the use of VR to improve pain, fatigue, and emotional distress in people with cancer at different stages of the cancer trajectory.

Optipharm: Enhancing pharmacological management skills in healthcare students for geriatric care through gamified e-learning.

Background: Complexities in older patient care and frequent polypharmacy requires tailored tools, specific skills and interdisciplinary collaborations. Traditional disease-centered education often overlooks these issues. Despite digital gamification's relevance in health education, limited exploration exists for gamified platforms addressing polypharmacy, especially within comprehensive geriatric assessment (CGA).

Radiative Cooling Properties of Portlandite and Tobermorite: Two Cementitious Minerals of Great Relevance in Concrete Science and Technology.

Although concrete and cement-based materials are the most engineered materials employed by mankind, their potential for use in daytime radiative cooling applications has yet to be fully explored. Due to its complex structure, which is composed of multiple phases and textural details, fine-tuning of concrete is impossible without first analyzing its most important ingredients. Here, the radiative cooling properties of Portlandite (Ca(OH)) and Tobermorite (CaSiO(OH)·4HO) are studied due to their crucial relevance in cement and concrete science and technology.

Comprehensive Characterisation of a Low-Frequency-Vibration Energy Harvester.

In this paper, we describe a measurement procedure to fully characterise a novel vibration energy harvester operating in the ultra-low-frequency range. The procedure, which is more thorough than those usually found in the literature, comprises three main stages: modelling, experimental characterisation and parameter identification. Modelling is accomplished in two alternative ways, a physical model (white box) and a mixed one (black box), which model the magnetic interaction via Fourier series.

"Perinatal loss, a devastating cyclone": A situation-specific nursing theory.

Purpose: The aim of this paper is to develop a preliminary theory that explores in depth into understanding the experiences of women who have suffered a spontaneous perinatal loss during any trimester of their pregnancy regarding their emotional response to this loss.

Design: A grounded theory approach was used, and 25 in-depth interviews were conducted with Spanish women who suffered a spontaneous perinatal loss.

Methods: Theoretical sampling and constant comparative analysis were used to reach theoretical saturation.

Crop grey water footprints in China: The impact of pesticides on water pollution.

Agricultural water pollution is a significant challenge in China, a rapidly growing economy with a large agricultural sector. The grey water footprint (WF) is a tool for evaluating freshwater pollution. It expresses pollution in volumetric units identifying the pollutant that theoretically needs most water to be diluted to accepted water quality standards.