135 results match your criteria: "Psychiatric hospital "Sveti Ivan"[Affiliation]"

Article Synopsis
  • The study focuses on the challenges of managing disease recurrence in early-stage hormone receptor-positive (HR+), HER2-negative breast cancer due to its biological complexity and the presence of PIK3CA mutations.
  • Approximately 30-40% of advanced HR+/HER2- breast cancer patients have PIK3CA mutations, which are linked to poor prognosis by activating pathways that promote cell growth.
  • The research found that patients with the PIK3CA mutation, particularly the H1047 variant, had a lower risk of disease recurrence compared to those without the mutation, suggesting its potential as a biomarker for personalized treatment strategies.
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The aim of this study was to evaluate the association between the Mediterranean diet (MD) and the accumulation of advanced glycation end products (AGEs) measured by skin autofluorescence. This cross-sectional study included 1016 healthy students from the University of Split, Croatia. Participants completed a self-administered questionnaire.

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Purpose Of Review: Although cancer incidence is similar between individuals with severe mental disorders (SMD) and the general population (GP), survival rates are lower, particularly in those with schizophrenia. While the scientific and medical communities acknowledge sex differences in cancer mechanisms, including risk factors and cancer types, less is known about sex and gender disparities in incidence, mortality, and care pathways among those with SMD. This review aims to explore these differences in cancer among individuals with SMD.

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Physical multimorbidity in psychiatric patients with personality disorders: Insights within the ICD-11 framework.

Gen Hosp Psychiatry

June 2024

Department of Psychiatry and Psychological Medicine, University Hospital Center Zagreb, Zagreb, Croatia; School of Medicine, University of Zagreb, Zagreb, Croatia.

Objective: Recent research has revealed poor physical health among individuals with personality disorders (PDs). We aimed to compare chronic physical illnesses (CPI) and chronic physical multimorbidity (CPM) prevalence between the general population (GEP) and PD patients, and to explore the relationship between CPM and various aspects of PD, predominantly within the ICD-11 framework.

Methods: This cross-sectional study included 126 PD patients and 126 matched controls from the GEP.

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The consequences of the new European reclassification of non-invasive brain stimulation devices and the medical device regulations pose an existential threat to research and treatment: An invited opinion paper.

Clin Neurophysiol

July 2024

Department of Head and Skin - Psychiatry and Medical Psychology, Ghent Experimental Psychiatry (GHEP) Lab, Ghent University, Ghent, Belgium; Vrije Universiteit Brussel (VUB), Universitair Ziekenhuis Brussel (UZ Brussel), Department of Psychiatry, Brussels, Belgium; Department of Electrical Engineering, Eindhoven University of Technology, Eindhoven, the Netherlands.

Article Synopsis
  • - A lot of neuroscience research in Europe uses methods like transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS), which are important for studying brain function.
  • - New EU regulations, particularly the Medical Device Regulation (MDR), have created confusion and problems in the non-invasive brain stimulation field, as they categorize some non-medical NIBS products with high-risk invasive devices.
  • - To address the negative impact of overregulation on research and innovation, a diverse group of stakeholders, including researchers and ethicists, has come together to promote discussions aimed at improving regulatory practices.
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Article Synopsis
  • A study looked at how doctors in Europe treat people with post-traumatic stress disorder (PTSD) because there are more traumatic events happening recently.
  • Out of 611 doctors, most recommended using antidepressants like sertraline, but there were differences in medicine choices based on where the doctors were from in Europe.
  • The findings show that while many doctors agree on treatment methods, differences in practice suggest that more communication and education are needed to follow treatment guidelines better across Europe.
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Introduction: External stressors, such as COVID-19 pandemic and earthquake, can cause an increase in substance use and addictive behavior in persons with severe mental illnesses (SMI). We analyzed the changes and predictors of substance use and addictive behavior in SMI during these double disasters in Croatia.

Methods: Questionnaires exploring the presence of substance or behavior addiction disorder, mental ill health [Depression Anxiety Stress Scales-21 (DASS-21), Insomnia Severity Index (ISI), Perceived Stress Scale (PSS), Obsessive-Compulsive Inventory-Revised], coping mechanisms, and perceived social support [Multidimensional Scale of Perceived Social Support (MSPSS)] were administered among 90 participants with SMI included in the RECOVER-E study in May/June 2020 (first COVID-19 wave, Zagreb earthquake) and in December 2020/January 2021 (second COVID-19 wave, Petrinja earthquake).

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Introduction: The aim of this study was to investigate attitudes and routine procedures in point of care testing (POCT) among non-laboratory and laboratory healthcare professionals in Croatia.

Materials And Methods: The Working Group (WG) for POCT of the Croatian society of medical biochemistry and laboratory medicine has designed two anonymous surveys for laboratory staff and non-laboratory staff with a total of 44 questions/statements on POCT (27 questions for non-laboratory staff and 17 for laboratory staff). Surveys were sent to 184 medical biochemistry laboratory (MBL) managers, the Croatian medical chamber and the Croatian chamber of nurses.

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The aim of the study was testing the hypothesis that body height has a moderating effect on the association of weight and chronic low back pain (LBP) induced disability, and that this moderating effect is different in women and men. We performed a nested cross-sectional analysis using data collected at baseline in a prospective cohort study conducted in 2008-2009 at a special hospital for medical rehabilitation in Croatia. The outcome was the Roland-Morris Disability Questionnaire (RMDQ) score.

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Objectives: To assess the efficacy of repetitive transcranial magnetic stimulation (rTMS) with an H1 coil as a treatment for hopelessness in patients with major depressive disorder (MDD).

Methods: We conducted a randomised controlled trial in a tertiary psychiatric institution in Croatia, including patients diagnosed with MDD without psychotic symptoms and with clinically relevant hopelessness. High-frequency (18 Hz) rTMS with an H1 coil was administered over four weeks on the left dorsolateral prefrontal cortex.

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Introduction: We aimed to evaluate how the presence of individual neuropsychiatric symptoms in non-institutionalised patients with dementia is associated with caregiver burden of their informal caregivers, family members.

Methods: We performed a cross-sectional study on a total of 131 pairs of one informal caregiver family member and non-institutionalised patient with dementia in a family medicine practices in a city of Zagreb, Croatia. Caregiver measures included Zarit Burden Interview (ZBI) whereas patient measures included Mini mental state examination (MMSE), Barthel index and Neuropsychiatric Inventory Questionnaire (NPI-Q).

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Background: The trends of recreational use of cannabis and use of cannabis for medical indications (i.e. "medical cannabis") have grown in recent years.

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Editorial: Refugees, migrants and displaced populations need better mental health support.

Curr Opin Psychiatry

September 2023

Department of Psychiatry and Psychological Medicine, University Hospital Center Zagreb, Psychiatric Hospital 'Sveti Ivan', School of Medicine, University of Zagreb and Faculty of Dental Medicine and Health, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia.

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Background: High heterogeneity exists in estimates of the share of and absolute costs of informal care (IC) for individuals diagnosed with dementia.

Objective: To assess the differences in the share of and absolute costs of IC between subpopulations defined by latent profiles of activities of daily living (ADLs), neuropsychiatric symptoms, and global cognitive functioning.

Methods: We performed a nested cross-sectional analysis of data collected from 2019-2021 at the Zagreb-Zapad Health Center, Zagreb, Croatia, from a sample of patients and their caregivers.

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Background: Training and practice in neuropsychiatry varies across the world. However, little is known about the experiences and opinions of early career psychiatrists (ECPs) across different countries regarding neuropsychiatry.

Aims And Method: To investigate neuropsychiatry training experiences, practices and opinions among ECPs across different countries.

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Article Synopsis
  • Patients who have had acute coronary syndrome (ACS) are at a higher risk of developing posttraumatic stress disorder (PTSD), which can negatively affect their survival; however, the actual rates of PTSD can differ significantly among studies due to reliance on self-reported surveys.
  • This study aims to assess the prevalence of PTSD in a large group of patients undergoing cardiac rehabilitation after ACS and to compare their characteristics with a control group that does not have PTSD.
  • The research involved 504 participants from a cardiac rehabilitation program in Croatia, utilizing both self-assessment questionnaires and clinical interviews to identify patients with PTSD and match them with non-PTSD patients based on clinical variables for comparison.
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Article Synopsis
  • * Results indicate that AD patients have significantly higher plasma BDNF concentrations than those with MCI.
  • * A negative correlation was found between BDNF levels and cognitive function, suggesting that higher BDNF might reflect the body's response to neurodegeneration in more severely impaired individuals.
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Article Synopsis
  • Researchers analyzed genetic data from over 785,000 individuals of European descent to find 43 specific genomic regions related to reproductive success, measured by the number of children and instances of childlessness.
  • These genetic regions influence various factors tied to reproduction, such as puberty onset, age at first birth, and conditions like endometriosis, highlighting complex biological networks at play.
  • The study also uncovered a potential trade-off between higher reproductive output and shortened reproductive lifespan in certain genes, suggesting some genetic traits are linked to ongoing natural selection affecting fertility.
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BACKGROUNDMajor depressive disorder (MDD) can benefit from novel interventions and personalization. Deep transcranial magnetic stimulation (Deep TMS) targeting the lateral prefrontal cortex (LPFC) using the H1 coil was FDA cleared for treatment of MDD. However, recent preliminary data indicate that targeting the medial prefrontal cortex (MPFC) using the H7 coil might induce outcomes that are as good or even better.

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The aim of this study was to compare the effectiveness of two treatment modalities for patients diagnosed with borderline personality disorder (BPD). A total of 100 psychiatric patients diagnosed with BPD participated in this study. Among them, 50 patients were outpatients who attended the Reason and Emotion (RIO) program, and the remaining 50 were inpatients who were treated on psychotherapeutic ward at the same hospital.

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Background: While shared clinical decision-making (SDM) is the preferred approach to decision-making in mental health care, its implementation in everyday clinical practice is still insufficient. The European Psychiatric Association undertook a study aiming to gather data on the clinical decision-making style preferences of psychiatrists working in Europe.

Methods: We conducted a cross-sectional online survey involving a sample of 751 psychiatrists and psychiatry specialist trainees from 38 European countries in 2021, using the Clinical Decision-Making Style - Staff questionnaire and a set of questions regarding clinicians' expertise, training, and practice.

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