15,561 results match your criteria: "Psychiatric Institute[Affiliation]"

There has been an increasing interest in identifying the biological underpinnings of human time perception, for which purpose research in non-human primates (NHP) is common. Although previous work, based on behaviour, suggests that similar mechanisms support time perception across species, the neural correlates of time estimation in humans and NHP have not been directly compared. In this study, we assess whether brain evoked responses during a time categorization task are similar across species.

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Objective: Establish whether pregnancies complicated by gestational diabetes mellitus (GDM) are associated with a fetal cardiac phenotype that predisposes to arrhythmia; utilising measurements derived from non-invasive abdominal fetal ECG.

Design: Prospective observational study.

Setting: Three tertiary obstetric units, United Kingdom.

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Background: Acceptance and commitment therapy (ACT) is promising in the treatment of early psychosis. Augmenting face-to-face ACT with mobile health ecological momentary interventions may increase its treatment effects and empower clients to take treatment into their own hands.

Objective: This study aimed to investigate and predict treatment engagement with and acceptability of acceptance and commitment therapy in daily life (ACT-DL), a novel ecological momentary intervention for people with an ultrahigh risk state and a first episode of psychosis.

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Objectives: This study aims to evaluate rates of public insurance participation among the different psychotherapist professions as well as among psychiatrists. In addition, it seeks to assess individual and contextual factors that are associated with public insurance participation.

Background: Historically, Medicaid- and Medicare-insured individuals have faced unique barriers to access to mental health professionals.

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Article Synopsis
  • * This chapter highlights the serial frequency discrimination task (SFDT), which assesses early auditory processing and learning, particularly in conditions like dyslexia and schizophrenia, by having participants compare pitches of paired tones.
  • * The SFDT reveals important brain interactions, especially between cognitive control and perceptual regions, and informs the development of medications targeting N-methyl-D-aspartate receptors (NMDAR), potentially helping treat cognitive deficits in neuropsychiatric disorders.
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Deficits in cognitive control contribute to behavioral impairments across neuropsychiatric disorders. Cognitive control is captured as a construct in the Research Domain Construct (RDoC) matrix and incorporate subdomains of goal selection, response selection, and performance monitoring. Relevant tasks for these subdomains include the "AX" version of the continuous performance task (goal selection) and the Go/NoGo and Stop-Signal reaction time tasks (response selection).

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Functional magnetic resonance imaging (fMRI) is a noninvasive technique for measuring brain activity that uses MRI to measure the blood oxygen level dependent (BOLD) signal. Over the 30+ years since the technique was first described (Ogawa et al. 1990), BOLD-fMRI has uncovered much about the organization and function of the human brain and is now beginning to fulfill its promise as a tool for diagnostic and prognostic biomarker of psychiatric conditions.

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Fidelity to Common Elements of Coordinated Specialty Care: Outcomes of Clients With First-Episode Psychosis.

Psychiatr Serv

November 2024

Westat, Rockville, Maryland (Rosenblatt, George, Ghose, Zhu, Ren, Krenzke, Opsomer); Abt Associates, Durham, North Carolina (Daley); New York State Psychiatric Institute and Department of Psychiatry, Vagelos College of Physicians and Surgeons, Columbia University, New York City (Dixon); School of Medicine, University of Maryland, Baltimore (Goldman).

Objective: The present study examined whether clients enrolled in coordinated specialty care (CSC) programs for first-episode psychosis (FEP) across 22 states and territories showed improved clinical and functional outcomes and assessed whether program- or client-level predictors were associated with client outcomes. The study included CSC programs that subscribe to a variety of models, including Early Assessment and Support Alliance, OnTrack, and NAVIGATE.

Methods: Deidentified demographic and outcome data were collected from clients (N=770) receiving CSC services in 36 programs at the time of program entry and every 6 months for up to 18 months.

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Learning occurs across multiple timescales, with fast learning crucial for adapting to sudden environmental changes, and slow learning beneficial for extracting robust knowledge from multiple events. Here, we asked if miscalibrated fast vs slow learning can lead to maladaptive decision-making in individuals with problem gambling. We recruited participants with problem gambling (PG; N = 20; 9 female and 11 male) and a recreational gambling control group without any symptoms associated with PG (N = 20; 10 female and 10 male) from the community in Los Angeles, CA.

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Introduction: To assess the association of race and ethnicity with self-reported personal protective equipment shortages during the COVID-19 pandemic among healthcare workers in New York.

Methods: The COVID-19 Healthcare Personnel Study of New York was a prospective cohort study of HCWs with baseline data collected in April 2020 and follow-up data collected in February 2021. Multivariable logistic regression modeling was used to estimate the adjusted OR and 95% CIs of personal protective equipment shortages associated with race and ethnic minority status.

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Adverse Childhood Experiences and Insufficient Sleep.

Acad Pediatr

November 2024

Global Psychiatric Epidemiology Group (S Forthal, S Lin, and K Cheslack-Postava), Division of Child and Adolescent Psychiatry, Department of Psychiatry, Columbia University-New York State Psychiatric Institute, New York, NY. Electronic address:

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Background: A prolonged first episode of psychosis (FEP) without adequate treatment is a predictor of poor clinical, functional, and health outcomes and significant economic burden. Team-based "coordinated specialty care" (CSC) for early psychosis (EP) has established effectiveness in promoting clinical and functional recovery. However, California's CSC program implementation has been unsystematic and could benefit from standardizing its processes and data collection infrastructure.

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Article Synopsis
  • Psychedelic-assisted therapy (PAT) with substances like psilocybin and MDMA shows potential for treating depression and PTSD, with possible approval as medicines within the next decade.
  • A study involving 879 U.S. healthcare professionals found most respondents had strong belief in the therapeutic benefits of these substances, but exhibited low knowledge about their risks and uses.
  • Factors such as prior psychedelic use, greater self-rated knowledge, younger age, and specific professional roles influenced openness to using these therapies, highlighting the need for more training and education on the topic.
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Who transitions to bipolar disorder? A comparison of major depressive disorder, anxiety, and ADHD.

J Affect Disord

February 2025

Department of Psychiatry and Behavioral Science, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA. Electronic address:

Article Synopsis
  • Diagnostic delays in Bipolar Disorder (BD) are common and the study aimed to understand conversion rates from other disorders like Major Depressive Disorder (MDD), anxiety, and ADHD using a large dataset from Johns Hopkins Medicine.
  • Of the 21,341 patients studied, 1,232 transitioned to BD, with one-year conversion rates of 4.2% for MDD, 3.4% for anxiety, and 4.0% for ADHD, highlighting certain risk factors like age, treatment setting, and medication.
  • The findings suggest that patients with MDD face the highest risk of developing BD, while anxiety disorders and ADHD are also significant precursors, especially in adults.
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Predictors of study dropout in cognitive-behavioural therapy with a trauma focus for post-traumatic stress disorder in adults: An individual participant data meta-analysis.

BMJ Ment Health

November 2024

Department of Clinical, Neuro- and Developmental Psychology, World Health Organization Collaborating Center for Research and Dissemination of Psychological Interventions, Amsterdam Public Health Research Institute, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.

Background: Available empirical evidence on participant-level factors associated with dropout from psychotherapies for post-traumatic stress disorder (PTSD) is both limited and inconclusive. More comprehensive understanding of the various factors that contribute to study dropout from cognitive-behavioural therapy with a trauma focus (CBT-TF) is crucial for enhancing treatment outcomes.

Objective: Using an individual participant data meta-analysis (IPD-MA) design, we examined participant-level predictors of study dropout from CBT-TF interventions for PTSD.

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Compulsory interventions, including compulsory nasogastric tube feeding, are sometimes necessary for youth with life-threatening anorexia nervosa. However, these interventions are also potentially traumatic for patients and clinicians alike. To improve early recognition and prevention of compulsory interventions, we evaluated common factors among youth with anorexia nervosa who receive compulsory treatment.

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Background: Rates of cannabis use disorder (CUD) have increased disproportionately among Veterans Administration (VA) patients with psychiatric disorders compared to patients with no disorder. However, VA patient samples are not representative of all U.S.

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Article Synopsis
  • Electroconvulsive therapy (ECT) is effective for major depressive disorder, but individual responses vary and are hard to predict due to differences in symptoms.
  • The study analyzed data from 161 patients to determine which specific baseline depression symptoms could predict remission using a Mixed Graphical Model approach.
  • Results showed that suicidality negatively predicted remission, while symptoms like psychomotor retardation and hypochondriasis were positively associated with better treatment outcomes.
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Introduction: Little is known about how pharmacists' attitudes and stigma toward naloxone and Medication for opioid use disorder (MOUD) influence effective linkage to treatment. We examine the psychometrics of a new Pharmacist Opioid Use Disorder Perceptions Questionnaire (P-OUDP-Q), a multidimensional measure to examine pharmacists' stigma and perceptions related to MOUD in the New York State (NYS) site of the HEALing Communities Study.

Methods: The study recruited a sample of 324 pharmacists from 16 counties in NYS between January and June 2022.

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Excessive information sampling in psychiatric patients characterized by high trait anxiety has been inconsistently linked with alterations in inferential and valuation processes. Methodological limitations could account in part for these inconsistencies. To address this, computational models of inference and valuation were applied to data collected from a transdiagnostic sample of adults with and without an anxiety or compulsive disorder using a version of the beads task with enhanced experimental controls.

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