3,138 results match your criteria: "Psittacosis"

Background: Psittacosis is a zoonotic disease with a low incidence rate and a lack of specificity in clinical manifestations, making it prone to be missed, misdiagnosed, and even cause delayed treatment for patients. Metagenomic next-generation sequencing (mNGS) was successfully performed for the diagnosis of a young patient with psittacosis progressing to acute respiratory distress syndrome (ARDS), and precisely targeted antibiotic treatment was promptly administered. Additionally, a comprehensive review was conducted on 68 cases of psittacosis complicated with ARDS, with the goal of improving the clinical awareness of this disease.

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Psittacosis Pneumonia Features, Distinguishing Characteristics, and Outcomes: A Retrospective Study.

Infect Drug Resist

December 2024

Department of Infectious Diseases, Shaoxing People's Hospital, Shaoxing, Zhejiang, People's Republic of China.

Purpose: Psittacosis is an often-neglected cause of community acquired pneumonia (CAP). The limited diagnostic methods for psittacosis pneumonia invariably result in an unfavourable prognosis. Consequently, the early detection of psittacosis pneumonia is crucial.

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Background: Psittacosis is a zoonotic infectious disease caused by () infection, which can be transmitted by birds, poultry and wild animals. The symptoms and imaging findings of pneumonia are atypical and primarily rely on etiological diagnosis. The incidence of infection has been significantly underestimated because of the low sensitivity and poor timeliness of traditional diagnostic methods.

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Omadacycline in the Treatment of Pneumonia: A Retrospective Study on Efficacy and Safety.

Br J Hosp Med (Lond)

November 2024

Department of Critical Care Medicine, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.

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Introduction of Chlamydia psittaci into a hospital area by feral pigeons.

Acta Trop

December 2024

Laboratório de Ecopatologia de Aves, Departamento de Patologia, Faculdade de Medicina Veterinária e Zootecnia, Universidade de São Paulo, Av. Prof. Dr. Orlando Marques de Paiva, 87, São Paulo, SP, Brasil, 05508-270. Electronic address:

Pigeons are associated with zoonotic pathogens such as Chlamydia psittaci, the main causative agent of avian chlamydiosis, and related to psittacosis cases in humans worldwide. The aim of the present study was to investigate the occurrence of C. psittaci in feral pigeons (Columba livia) and environmental samples from places frequented by pigeons in a Brazilian hospital area.

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Molecular Detection and Genotyping of in Birds in Buenos Aires City, Argentina.

Animals (Basel)

November 2024

Servicio Bacteriología Clínica, INEI-ANLIS "Dr. Carlos G. Malbrán", Ciudad Autónoma de Buenos Aires C1282AFF, Argentina.

is a bacterium that infects several species of birds and mammals. It is the causal agent of avian chlamydiosis and psittacosis in humans and it is globally distributed. is one of the main zoonotic pathogens transmitted by birds.

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Chlamydia psittaci (C. psittaci) is a multi-host pathogen that elicits robust innate immune responses in macrophages. Chlamydiae target host mitochondria to manipulate the cellular fate and metabolic functions.

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Diagnosis and treatment experience of Chlamydia psittaci pneumonia: A multicenter retrospective study in China.

BMC Infect Dis

November 2024

Department of Respiratory and Critical Care, Emergency and Critical Care Medical Center, Beijing Shijitan Hospital, Capital Medical University, Beijing, China.

Article Synopsis
  • Chlamydia psittaci pneumonia cases are rising and can lead to severe respiratory issues, complicating diagnosis due to ineffective detection methods.
  • A study of 61 pneumonia cases in China classified them into severe and non-severe groups to analyze differences in symptoms, lab results, and treatment.
  • Results indicated fever as a key symptom, with elevated CRP and PCT levels being notable, while doxycycline is identified as the preferred treatment for severe cases.
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The obligate intracellular bacterial genus Chlamydia harbours species with zoonotic potential, particularly C. psittaci, causative agent of psittacosis, and C. abortus, which may lead to miscarriage in pregnant women.

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Chronicles from the Nest: A Case of Psittacosis in India.

J Assoc Physicians India

November 2024

Clinical Assistant, Department of Internal Medicine, Sir Ganga Ram Hospital, Delhi, India.

Psittacosis is a rare zoonotic disease caused by a gram-negative obligate intracellular bacterium , which is transmitted through contact with infected birds. It comprises approximately 1% of all community-acquired pneumonia cases. However, this can be just the tip of the iceberg pertaining to the lack of routine testing and awareness of this disease entity, thereby requiring a high index of suspicion for its diagnosis.

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Background: The typical clinical symptoms of psittacosis pneumonia include fever, dry cough, and chills. Sudden sensorineural hearing loss is a relatively uncommon condition in pneumonia caused by Chlamydia psittaci. In this study, we reported a rare case of Chlamydia psittaci pneumonia presented as hearing loss.

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Objectives: Detection and diagnosis of () pneumonia is often overlooked due to conventional methods limitations and similarity to other atypical community acquired pneumonia (CAP). Using mNGS, we aimed to distinguish psittacosis from legionellosis for early pneumonia diagnosis and better prognosis.

Methods: Thirty-seven patients diagnosed with atypical CAP were enrolled in this retrospective study, including 14  pneumonia and 23 () pneumonia.

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is an obligate intracellular gram-negative bacterium with a unique biphasic developmental cycle. It is a zoonotic pathogen with a wide range of hosts and can cause avian chlamydiosis in birds and psittacosis in humans. The pathogen is transmitted mainly through horizontal transmission between birds.

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V-V ECMO for severe Chlamydia psittaci pneumonia presenting with sudden cardiac arrest: A case report and literature review.

Medicine (Baltimore)

November 2024

Department of Critical Care Medicine, The Quzhou Affiliated Hospital of Wenzhou Medical University, Quzhou People's Hospital, Quzhou, Zhejiang, China.

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Chlamydiosis in Animals.

Animals (Basel)

October 2024

Moredun Research Institute, Pentlands Science Park, Bush Loan, Penicuik EH26 0PZ, UK.

The family consists of Gram-negative, obligate intracellular bacteria that replicate within the cells of a diverse range of hosts. These hosts include domesticated animals such as cats, dogs, and livestock, as well as wildlife like koalas and birds, exotic species such as reptiles and amphibians, and humans. Chlamydial infection can result in various clinical signs, including respiratory diseases, reproductive failures, ocular pathologies, and enteritis, though the infected organism may remain asymptomatic.

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Article Synopsis
  • * A patient suffering from this disease developed a splenic infarction during their hospital treatment but made a good recovery after receiving anti-infective and anticoagulant therapies.
  • * The study emphasizes the need for further research to better understand the link between severe Chlamydia psittaci pneumonia and complications such as splenic infarction.
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Circulation of avian Chlamydia abortus in the Netherlands and community-acquired pneumonia: an outbreak investigation and retrospective cohort study.

Lancet Infect Dis

October 2024

Department of Medical Microbiology (and reference laboratory for human chlamydia infections from animal origin), Zuyderland Medical Center, Sittard-Geleen, Netherlands.

Background: In 2021, a novel group of Chlamydia strains in wild birds was classified as avian Chlamydia abortus, with unknown zoonotic potential. We report relevant features of avian C abortus infections from a Dutch family cluster and unrelated historical cases using clinical, epidemiological, and microbiological data.

Methods: An outbreak of avian C abortus started in the Netherlands in December, 2022.

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CRISPR/Cas9-edited duck enteritis virus expressing Pmp17G of Chlamydia psittaci induced protective immunity in ducklings.

Pathog Dis

February 2024

Beijing Animal Husbandry Station, Beijing Municipal Bureau of Agriculture and Rural Affairs, Beijing 100107, China.

Chlamydia psittaci is threatening to the animal industry and human beings. Live attenuated duck enteritis virus (DEV) is considered a good vaccine vector. In the present study, the Pmp17G antigen of C.

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Comparison of clinical, laboratory and radiological characteristics between COVID-19 and Chlamydia psittaci pneumonia: a multicenter retrospective study.

Sci Rep

October 2024

Department of Respiratory Medicine, National Key Clinical Specialty, Branch of National Clinical Research Center for Respiratory Disease, Xiangya Hospital, Central South University, Changsha, 410008, China.

Article Synopsis
  • - The study compares Chlamydia psittaci pneumonia (CPP) and COVID-19, revealing that both share similar outbreak patterns and symptoms but have distinct clinical manifestations.
  • - Key differences include a higher incidence of nervous system symptoms and worse inflammatory indicators in CPP patients, along with a tougher prognosis reflected in higher mortality and severe pneumonia rates.
  • - A nomogram was developed based on five risk factors—nervous system symptoms, lymphocytes, creatine kinase levels, bilateral lung lesions, and ground-glass opacity—to effectively distinguish CPP from COVID-19, achieving a high concordance index of 0.989.
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Article Synopsis
  • * A study tested 516 pet birds in Hong Kong, discovering that 0.97% were infected with C. psittaci, mostly from pet shops, highlighting potential sources of transmission.
  • * Genetic analysis showed that all strains identified belonged to Genotype A and were similar to those found in various other species and locations, confirming the presence of this zoonotic pathogen in captive birds and the risks it poses to humans and wildlife.
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Avian chlamydiosis is a serious avian infection that carries a significant zoonotic danger to the poultry industry. The respiratory co-infections caused by the low pathogenic avian influenza virus H9N2 (LPAIV H9N2) also cause significant financial losses in the poultry industry. The purpose of this study was to examine the pathogenicity of Chlamydophila psittaci, and LPAIV H9N2 individually and in combination in broiler chickens, as well as to determine whether or not aqueous neem (Azadirachta indica) leaf extract is effective against infections caused by these pathogens.

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Prevalence and genotypes of Chlamydia psittaci in birds and related workers in three cities of China.

PLoS One

August 2024

National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.

Article Synopsis
  • Chlamydia psittaci is a zoonotic pathogen found in birds that can cause severe respiratory diseases in humans, particularly affecting those working in or living near poultry farms.
  • * In a study across three cities in China, researchers collected and tested fecal samples from various poultry species and swab and serum samples from poultry farm and zoo workers to assess the prevalence and genotypes of C. psittaci.
  • * The results showed that 3.13% of poultry samples and a higher percentage of human serum samples tested positive for the pathogen, with the identified strains indicating that human infections likely originated from poultry, while a new strain was found in peacocks.
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Article Synopsis
  • * Testing revealed he was infected with Chlamydia psittaci (C. psittaci), leading to the development of additional fungal and viral infections during treatment.
  • * Successful management required a combination of antibiotics and antifungal therapy, highlighting the need for early diagnosis and treatment to improve patient outcomes, especially in cases of immune suppression.
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A novel variant of Chlamydia psittaci causing human psittacosis in China.

Int J Infect Dis

October 2024

National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China. Electronic address:

From January 2022 to November 2022, sporadic psittacosis occurred in Lishui city, China. The patients were presented with fever, cough, and pulmonary infiltration. Their clinical symptoms were not relieved after receiving cephalosporin, penicillin, beta-lactamase inhibitors, and quinolones.

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