234 results match your criteria: "Pseudopapilledema"

A man in his early 20s was referred for refractive surgery evaluation. His best corrected distance visual acuity was 20/60 in both eyes. Preoperative manifest refraction was +13.

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Purpose: Peripapillary hyperreflective ovoid mass-like structures (PHOMS) have been recently described on optical coherence tomography (OCT) scans of the optic nerve. We aim to determine if there is a causal relationship between OCT measurements of the optic disc area (DA), scleral canal diameter (SCD) and refractive error (spherical equivalent, SE) on the presence of PHOMS.

Methods: Retrospective analysis of OCT scans which were graded for the presence or absence of PHOMS in children with suspected papilledema was undertaken.

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Clinical correlation of optic nerve head analysis performed by SD-OCT in children with pseudopapilledema and papilledema.

Photodiagnosis Photodyn Ther

December 2024

Assisstance Professor of Pediatric Neurology Department, Doctor Sami Ulus Pediatricand Trianing Hoapital Ankara, Turkey.

Purpose: To investigate some diagnostic indicators in optic nerve head (ONH) analysis of children with 'Pseudopapilledema' and 'Papilledema' by Spectral Domain Optical Coherence Tomography (SD-OCT).

Methods: Medical records of 52 children with optic disc swelling, who were followed up by the departments of pediatric neurology and ophthalmology between May 2018 and May 2019 were reviewed retrospectively. Cases were classified as group 1 (Papilledema secondary to Idiopathic Intracranial Hypertension) including 54 eyes of 27 cases, group 2 (Pseudopapilledema secondary to bilateral optic disc drusen) including 50 eyes of 25 cases and control group.

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Article Synopsis
  • - The text discusses pseudopapilledema, specifically caused by optic disc drusen (ODD), which can look similar to papilledema, posing a diagnostic challenge, especially in a young boy with Chiari malformation type 1.
  • - In such cases, advanced imaging techniques like fundus autofluorescence, optical coherence tomography (OCT), and B-scan ultrasonography are essential to differentiate between ODD and true papilledema due to elevated intracranial pressure (ICP).
  • - The consensus among specialists is to monitor patients with annual eye exams and imaging to catch any changes in the optic nerve head, as the presence of ODD doesn't rule out the possibility of future issues related to increased ICP
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Imaging the optic nerve with optical coherence tomography.

Eye (Lond)

August 2024

Department of Clinical Neurosciences, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.

Article Synopsis
  • Optical coherence tomography (OCT) is a special imaging tool that helps doctors see the inside of your eye without any surgery.
  • It measures different parts of the retina to check for problems with the optic nerve and can help diagnose eye diseases.
  • New technologies like artificial intelligence are making OCT even better, so doctors can understand eye issues more easily and provide better care.
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Article Synopsis
  • * A literature review was conducted using databases like PubMed and Google Scholar to gather evidence on the causes and differentiation methods for both conditions.
  • * Techniques such as Fundus fluorescein angiography, optical coherence tomography, and MRI help distinguish between the two, and in some cases, more invasive procedures like lumbar punctures may be necessary.
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Article Synopsis
  • Persistent fetal vasculature (PFV) is a congenital eye disorder caused by the failure to properly absorb the hyaloid system and often appears unilaterally in three forms: anterior, posterior, and mixed.
  • A seven-year-old patient was referred for bilateral papilledema and showed excellent visual acuity, but fundus examination revealed signs of pseudopapilledema and a distinct band near the optic disc.
  • Ocular ultrasound and optical coherence tomography (OCT) confirmed a diagnosis of bilateral posterior PFV, indicating a case of papillary traction syndrome.
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Article Synopsis
  • The study aimed to create an AI model that helps distinguish between pediatric pseudopapilledema and true papilledema using fundus photographs from children under 18 years old.
  • A total of 851 fundus images from 235 children were analyzed by the AI, which utilized a DenseNet backbone and a specialized neural network for classification.
  • Results showed that the AI model achieved higher accuracy and sensitivity compared to human experts, especially in detecting mild cases of papilledema, although its specificity was comparable to that of the experts.
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The Increasing Burden of Emergency Department and Inpatient Consultations for "Papilledema".

J Neuroophthalmol

March 2024

Department of Ophthalmology (HJR, ALOS, MD, WB, GB, JHP, SK, BBB, NJN, VB), Neurology (SK, JGG, NJN, VB), and Emergency Medicine (AMP, MTK, DWW), Emory University School of Medicine, Atlanta, Georgia; Department of Epidemiology (BBB), Rollins School of Public Health, Emory University, Atlanta, Georgia; and Department of Neurological Surgery (NJN), Emory University School of Medicine, Atlanta, Georgia.

Article Synopsis
  • The study investigates the rising trend of emergency department (ED) visits for suspected papilledema due to various factors like increased idiopathic intracranial hypertension (IIH) cases and limited neuro-ophthalmology access.
  • Over a year, 153 patients were referred for papilledema, with 58% diagnosed with bilateral optic disc edema; 89% of those had confirmed papilledema related to intracranial hypertension.
  • Patients with secondary causes of intracranial hypertension were generally older and presented with additional neurological symptoms compared to those with IIH, highlighting the need for targeted evaluations in these consultations.*
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The Papilledema Dilemma: Myopic Pseudopapilledema From Peripapillary Hyper-Reflective Ovoid Mass-like Structures.

Pediatr Neurol

March 2024

Neuro-ophthalmology Department, Singapore National Eye Centre, Singapore; Singapore Eye Research Institute, Singapore; Angers University Hospital, Angers, France; Copenhagen University Hospital, Copenhagen, Denmark; Duke-NUS Medical School, Singapore. Electronic address:

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Advantages and Pitfalls of the Use of Optical Coherence Tomography for Papilledema.

Curr Neurol Neurosci Rep

March 2024

Department of Ophthalmology, Rigshospitalet, University of Copenhagen, Glostrup, Denmark.

Article Synopsis
  • Papilledema is optic disc swelling caused by high intracranial pressure and can lead to vision loss, making early diagnosis crucial for patient care.
  • The review emphasizes the advantages of optical coherence tomography (OCT) as a non-invasive imaging method to detect papilledema, especially when traditional ophthalmoscopy may not be reliable.
  • OCT can identify subtle changes like retinal nerve fiber layer thickening and assist in diagnosing related conditions, while also providing insights into treatment response and potential integration into advanced diagnostic models.
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Article Synopsis
  • The study focuses on diagnosing papilledema due to idiopathic intracranial hypertension (IIH) in pediatric patients who have optic disk drusen (ODD), which usually appears as pseudopapilledema.
  • Researchers reviewed medical records of children under 15 with confirmed ODD from 2019 to 2022 and found that 4.8% of these patients also had IIH.
  • The findings suggest clinicians should be aware of IIH symptoms and risk factors in ODD cases and conduct follow-up evaluations, including optical coherence tomography, for asymptomatic patients.
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Article Synopsis
  • The study investigates optic disc swelling in cancer patients at a tertiary center in Jordan, focusing on causes and outcomes from 2019 to 2020.
  • Among 58 patients, the majority were young females, with high intracranial pressure noted as the leading cause, often linked to CNS tumors.
  • Treatment included medications and surgeries, resulting in visual acuity improvement in 42% of affected eyes, despite a 19% mortality rate at a 12-month follow-up.
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Article Synopsis
  • A 9-year-old boy with worsening vision and optic neuritis showed a complex relationship between myopia progression, eye length changes, and thinning of the retinal nerve fiber layer (RNFL) in both eyes.
  • *Vision improved with steroid treatment, yet follow-up indicated ongoing RNFL and macular ganglion cell layer (mGCL) thinning over 16 months.
  • *The case emphasizes the importance of monitoring and managing eye health in young patients experiencing these interrelated issues.
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Understanding pseudopapilledema on spectral domain optical coherence tomography.

Indian J Ophthalmol

November 2023

Department of Optometry, Sankara Nethralaya, 18 College Road, Chennai, Tamil Nadu, India.

Article Synopsis
  • - The study explores the occurrence of optic nerve head drusen (ONHD), peripapillary hyperreflective ovoid mass-like structures (PHOMS), and horizontal hyperreflective lines (HHL) in patients diagnosed with pseudopapilledema using enhanced depth imaging spectral domain optical coherence tomography (EDI SD OCT).
  • - A total of 48 eyes from 27 patients with pseudopapilledema were compared to 20 control eyes, revealing that ONHD appeared in 39.48% of eyes, PHOMS in 64.6%, and HHL in 39.48%, with significant statistical results.
  • - The findings indicate that PHOMS are more prevalent than ONHD and HHL in patients
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Article Synopsis
  • The study aimed to compare clinical findings and imaging of pediatric patients with papilledema and pseudopapilledema to those of healthy children.
  • It included 90 children under 18, where OCT imaging revealed thicker retinal nerve fiber layers in those with papilledema compared to pseudopapilledema and control groups.
  • The study concluded that OCT can effectively differentiate between papilledema and pseudopapilledema, potentially sparing patients from unnecessary invasive tests.
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Article Synopsis
  • This study investigates the prevalence of peripapillary hyperreflective ovoid mass-like structures (PHOMS) in patients with acute Leber's Hereditary Optic Neuropathy (LHON) using structural optical coherence tomography (OCT).
  • Out of 16 patients examined, 57.1% showed PHOMS, predominantly located in the temporal region of the eye.
  • At a 12-month follow-up, PHOMS were found to have disappeared in most cases, suggesting they could indicate swollen retinal fibers.
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Article Synopsis
  • Chiari malformation 1 (CM1) is a condition where brain tissue herniates through the skull, typically noted when herniation measures over 3 or 5 mm.
  • A case study featuring a 55-year-old male revealed he had a 4.87 mm herniation, along with symptoms like bilateral papilledema and monocular vision loss.
  • Despite having CM1, his lumbar puncture showed normal intracranial pressure, raising questions about the typical association between papilledema and elevated pressure.
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Article Synopsis
  • Elevated intracranial pressure (eICP) is a critical condition requiring quick detection, and traditional methods can be invasive and involve radiation.
  • Ocular ultrasound offers a non-invasive way to detect optic disc elevation (ODE), which could serve as a useful marker for eICP.
  • A review of 29 studies showed that ODE has good sensitivity (70-90%) and high specificity (up to 100%) in identifying eICP, suggesting it could improve diagnostic accuracy if further researched.
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Article Synopsis
  • Optic disc drusen (ODD) are calcium deposits in the optic nerve that can lead to visual issues, but their causes and treatment options are not well understood.* -
  • The study reviewed and analyzed data from 8 studies involving over 27,000 individuals to estimate the prevalence of ODD using different diagnostic methods.* -
  • Current estimates suggest there are about 145 million people with ODD globally, a number likely to rise with population growth, highlighting the need for more research and awareness in healthcare. *
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Article Synopsis
  • * A 40-year-old woman with CRVO underwent extensive tests, which showed no systemic issues but revealed buried ONH drusen through ultrasonography.
  • * When diagnosing CRVO in young patients without systemic risk factors, it's important to consider ONH drusen and use ultrasonography to aid in diagnosis, especially if there's unusual disc swelling and nearby hemorrhages.
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