Diffuse large B-cell lymphoma mimicking the cervical epidural hematoma in a patient who underwent spinal manipulation therapy: a case report and literature review.

The diffuse large B-cell lymphoma (DLBCL) mimicking an epidural hematoma in the cervical spine is an extremely unique case. We present a case of a 42-year-old man, who presented to the emergency department with symptoms of tetraparesis after a session of spinal manipulation therapy. magnetic resonance imaging visualized a lesion located at C3-C7 causing spinal cord compression with surrounding soft tissue edema suggesting epidural hematoma.

Pathology and treatment methods in pantothenate kinase-associated neurodegeneration.

Purpose: The purpose of this review is to present current scientific reports on the pathophysiology, diagnosis and treatment of pantothenate kinase-associated neurodegeneration (PKAN).

Views: The condition is caused by a mutation in the PANK2 gene, which results in iron accumulation in the brain and changes in the functioning of biochemical pathways dependent on coenzyme A. There are two clinical types of PKAN, which differ in the time of onset of symptoms and speed of disease progression.

- impact on the cardiovascular risk, the intestine inflammation and obesity.

Contemporary scientific discussions are increasingly focusing on due to its complex influence on intestinal physiology. This article provides a comprehensive analysis of the various effects has on intestinal inflammation, while also exploring its potential associations with obesity and cardiovascular diseases. A systematic literature search was conducted using PubMed, Google Scholar, and ResearchGate with the following keywords: , obesity, cardiovascular risk, and inflammatory bowel diseases.

Pruritus prevalence and characteristics in Care and Treatment Facility and Geriatric Outpatient Clinic patients: a cross-sectional study using a standardized pruritus questionnaires.

Introduction: Chronic pruritus is one of the most common symptoms in geriatric patients. Pathogenesis of pruritus is multifactorial.

Aim: To evaluate the prevalence and characteristics of pruritus in geriatric patients and to characterise pruritus and explore its possible underlying causes.

Advancements and applications of laser technology in modern dentistry.

The use of lasers in dentistry has revolutionized dental procedures, providing signif i cant advantages over traditional techniques. Lasers offer enhanced precision, reduced bleeding, faster healing times, and improved patient comfort. This review explores CO2 lasers, diode lasers, Er, and Er, Cr lasers, and Photobiomodulation and Low-Level Laser Therapy (LLLT).

Hypothermic cardiac arrest: prognostic factors for successful resuscitation before rewarming.

Objective: To indicate factors predicting return of spontaneous circulation in patients with hypothermic cardiac arrest in the pre-rewarming period.

Methods: A multicenter retrospective study was conducted. We included patients who had suffered cardiac arrest caused by severe accidental hypothermia with a core body temperature of ≤ 28 °C.

Effects of β-Blockers on the Outcomes in Patients With Pulmonary Arterial Hypertension Stratified by the Presence of Comorbid Conditions: A Multicenter Prospective Cohort Study (BNP-PL).

Background: Current guidelines do not recommend β-blockers in pulmonary arterial hypertension (PAH) unless indicated by comorbidities. However, the evidence regarding the role of β-blockers in PAH is contradictory.

Research Question: What are the effects of β-blockers on clinical outcomes in patients newly diagnosed with PAH, and how do these outcomes differ based on the presence of cardiovascular comorbidities that are standard indications for β-blocker use?

Study Design And Methods: We analyzed data from 806 patients newly diagnosed with PAH enrolled prospectively in the Database of Pulmonary Hypertension in the Polish Population (BNP-PL).

Outcomes of extracorporeal life support in hypothermic cardiac arrest: Revisiting ELSO guidelines.

Aim Of The Study: Predictive factors for poor outcomes in hypothermic cardiac arrest (HCA) differ from those in normothermic out-of-hospital cardiac arrest (OHCA). This study aimed to evaluate the outcomes of extracorporeal life support (ECLS) in HCA patients who may not be considered eligible based on the guidelines set by the Extracorporeal Life Support Organization (ELSO).

Methods: A retrospective multicentre study included 127 HCA patients, divided into two groups: those meeting the ELSO eligibility criteria for ECLS, and those with at least one of the following ELSO exclusion criteria: age over 70 years, unwitnessed cardiac arrest, or asystole.

Diagnostic criteria and therapeutic implications of rapid-onset demyelinating polyneuropathies.

Guillain-Barré syndrome (GBS) and acute-onset chronic inflammatory demyelinating polyneuropathy (A-CIDP) are the most common autoimmune polyneuropathies. Their aetiology is unclear. The pathomechanism includes damage mainly to the myelin sheath and, in the long-term process, secondary axonal loss.

Lipids associated with autophagy: mechanisms and therapeutic targets.

Autophagy is a molecular process essential for maintaining cellular homeostasis, with its impairment or dysregulation linked to the progression of various diseases in mammals. Specific lipids, including phosphoinositides, sphingolipids, and oxysterols, play pivotal roles in inducing and regulating autophagy, highlighting their significance in this intricate process. This review focuses on the critical involvement of these lipids in autophagy and lipophagy, providing a comprehensive overview of the current understanding of their functions.

Fatal poisoning by dietary supplements accompanied by massive rhabdomyolysis and multiple organ failure.

Obesity epidemic and prevailing standards of desired body shape encourage society to use weight loss aids. Thermogenics, which are dietary supplements aimed at increasing energy expenditure, are particularly gaining popularity. These preparations can be easily purchased without prescription and have a complex composition, which means they can interact with numerous substances.

Intrauterine Shaping of Fetal Microbiota.

Mechanisms resulting from the physiological immaturity of the digestive system in children delivered before 32 weeks of gestation and, in particular, different interactions between the microbiome and the body have not been fully elucidated yet. Next-generation sequencing methods demonstrated the presence of bacterial DNA in the placenta and amniotic fluid, which may reflect bacterial populations that initiate intestinal colonization in utero. Numerous studies confirmed the hypothesis stating that intestinal bacteria played an important role in the pathogenesis of necrotizing enterocolitis (NEC) early- and late-onset neonatal sepsis (EONS and LONS).

Comprehensive management of pericoronitis in lower third molars: extraction, operculectomy, and coronectomy approaches.

Pericoronitis is a common dental condition involving the inflammation of soft tissues around a partially erupted wisdom tooth, typically the lower third molars. It is most frequently diagnosed in young adults aged 20-29, with a higher prevalence in women. The condition often results from the accumulation of bacteria and food debris under the operculum, leading to infection and inflammation.

Perceived stress and life satisfaction in pregnant women during the COVID-19 pandemic: the mediating role of fear of childbirth and self-esteem.

Background: The COVID-19 pandemic adversely affected the functioning and well-being of pregnant women. Negative feelings during pregnancy and the difficult pandemic situation may be the reason behind the perceived fear of childbirth, which can negatively affect the pregnant women's life satisfaction. On the other hand, some protective factors, such as self-esteem, might mediate the relationship between perceived stress and well-being in pregnant women.

Orbital floor reconstruction based on 3d printed model - case report.

Orbital fractures, constituting 10-25% of facial traumas, result from diverse mechanisms such as traffic accidents and assaults. These fractures present with characteristic symptoms like edema, diplopia, and infraorbital paraesthesia. Timely diagnosis and surgical intervention are paramount to mitigate long-term complications.

Surgical methods of managing the upper lip frenulum - a literature review.

The upper lip frenulum with an overgrown structure or improper attachment is a common cause of hygienic, orthodontic, or prosthetic issues that prompt surgical intervention. The following article presents the surgical methods for the elimination of the overgrown frenulum, discussing and comparing them. Commonly used and described in the literature methods for surgical correction of the upper lip frenulum include frenulectomy, frenuloplasty, and laser excision of the frenulum.

Case report: Comprehensive management of painful diabetic neuropathy-Addressing opioid-induced hyperalgesia through multimodal approaches.

Rationale: Diabetic neuropathy is a prevalent and debilitating complication of diabetes, necessitating effective pain management strategies. While pharmacological treatments, including opioids, are commonly employed, they pose significant challenges due to the risk of developing opioid-induced hyperalgesia (OIH). This case report aims to illustrate the efficacy of a comprehensive, multidisciplinary approach in managing painful diabetic neuropathy complicated by OIH.

Quality of life of caregivers of patients on home enteral nutrition.

Background: Home enteral nutrition (HEN) patients often rely heavily on caregivers (CGs), whose quality of life (QoL) is significantly impacted. This study aimed to identify potentially modifiable factors influencing the QoL of CGs of HEN patients.

Methods: A multicentre, cross-sectional study was conducted in three home nutrition centers from Jan 2021 to Jan 2022.

Positive Orientation and Feelings of Loneliness among Polish Students during the COVID-19 Pandemic.

: The COVID-19 pandemic was a time of limited direct contact with other people. The aim of this study was to determine the role of positive orientation and sociodemographic variables in the feelings of global, social and emotional loneliness and to seek predictors for loneliness among students during the COVID-19 pandemic. : The study was conducted on a group of 798 students at the University of Warmia and Mazury in Olsztyn (Poland) between January and March 2022.

Health Behaviours and the Quality of Life of Students of Medical Fields during the COVID-19 Pandemic.

(1) Background: Social distancing and closing down public spaces associated with learning, leisure and physical activity limited the spread of COVID-19. These measures had an impact not only on the economy and education but also on health behaviours and the quality of life of individuals affected by the restrictions. The aim of this study was to identify the role of health behaviours in the perception of the quality of life of students during the COVID-19 pandemic.