19,502 results match your criteria: "Prosthetic Heart Valves"

Article Synopsis
  • The study evaluates the accuracy of the Eko murmur analysis software (EMAS) in detecting valvular heart disease (VHD) by comparing it to echocardiography (ECHO) results.
  • Data from 1,029 individuals were analyzed, revealing that EMAS had a sensitivity of 39.4% and a specificity of 82.4% for detecting murmurs related to VHD.
  • While EMAS shows better sensitivity for certain VHD types, its overall limited sensitivity suggests it may not be reliable as a screening tool for all forms of VHD.
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Article Synopsis
  • Aortic valve calcification (AVC) is examined as a predictor for complications in transcatheter aortic valve implantation (TAVI), with a focus on its impact on intra-annular devices.
  • Patients with high AVC have a higher risk of developing mild to severe paravalvular leak (PVL) and conduction disorders requiring pacemaker implantation, indicating AVC's significant role in post-TAVI outcomes.
  • The study found that higher AVC levels predict poor 30-day clinical outcomes after TAVI, highlighting the importance of assessing AVC to improve patient management.
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Article Synopsis
  • Postoperative complications following valve surgery can include hematomas, bleeding, and acute thrombosis, with a complication rate of 0.7 to 3.5% per patient annually.
  • In a case study, a woman in her 50s experienced worsening dyspnea and chest pain after mitral valve replacement, leading to the discovery of a large mass in the right atrium via echocardiography, which was effectively excised.
  • Accurate imaging techniques like TTE and TEE are crucial for diagnosing and managing postoperative complications, highlighting the importance of skilled sonographers in preventing further complications in asymptomatic patients.
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Article Synopsis
  • * Out of 2,754 CS patients, 442 (16%) had VCS, with a higher median age (70 years) and a greater proportion of females (40.3%) compared to non-VCS patients, and the majority had native valve issues, particularly affecting the aortic valve.
  • * Patients with VCS had worse outcomes, showing higher 1-year (44% vs 37%)
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Introduction: Mechanical heart valve (MHV) replacement requires long-life anticoagulation due to the risk of Prosthetic Valve Dysfunction (PVD) and cardioembolism.

Methods: We report data from a prospective observational study conducted on MHV patients in the Khartoum Salam Centre for Cardiac Surgery built by 'Emergency,' an Italian Non-Governmental Organization, to evaluate the occurrence of PVD and associated risk factors.

Results: We prospectively followed 3647 patients, and 38 patients (rate 1.

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TAVI complication: Prosthetic valve leaflet dislodgment after post-dilatation.

Int J Surg Case Rep

November 2024

Heart Center, Kaplan Medical Center, Rehovot, affiliated with the Hebrew University, Jerusalem, Israel. Electronic address:

Introduction And Importance: Transcatheter aortic valve implantation (TAVI) is a minimally invasive procedure used to treat severe aortic stenosis. While TAVI is generally safe and effective, it can be complicated by rare adverse events such as prosthetic leaflet dislodgment leading to acute free aortic regurgitation.

Case Presentation: We report the case of a female patient who experienced acute free aortic regurgitation following elective TAVI.

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Background: Understanding ascending aortic aneurysm growth and associated risk factors is critical to advising appropriate echocardiographic follow-up intervals for patients. The aim of this study was to identify aortic aneurysm growth rate on serial echocardiography as well as the clinical and demographic variables that contribute to baseline aortic size and subsequent aortic growth.

Methods: Patients identified with ascending aortic aneurysms and undergoing serial echocardiograms within 5 years were evaluated.

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Infective endocarditis (IE) is a condition that predominantly affects native or prosthetic heart valves, which is currently on the rise due to the increase in invasive cardiology procedures, such as the utilization of cardiac implantable electronic devices and transcatheter interventions. The recommended imaging tests for diagnosis are 2D transthoracic echocardiography (2D TTE) and 2D transoesophageal echocardiography (2D TOE). However, these modalities present limitations in detecting vegetations and estimating their dimensions.

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Article Synopsis
  • Valvular Heart Disease (VHD) is a major cause of death, especially in older people, and this study explores the unknown risk factors associated with it.
  • The research utilizes machine learning techniques, including various classifiers like SVM, to analyze VHD cases and assess the effectiveness of these methods in diagnosis.
  • Findings indicate that combining SVM with Principal Component Analysis (PCA) offers the best performance, emphasizing the need for a comprehensive strategy to address the prevalence of VHD based on identified risk factors.
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Article Synopsis
  • Infective endocarditis (IE) is a serious infection that causes inflammation of the heart's inner lining, often increasing in patients receiving hemodialysis (HD).
  • A case study describes a 46-year-old obese male with a history of diabetes and renal disease who faced severe symptoms after missing dialysis sessions, including altered mental status and indications of septic shock.
  • The case emphasizes the need for urgent medical intervention and collaboration among healthcare teams to stabilize the patient and investigate potential infections linked to his condition.
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In cases of severe and recurrent infectious lesions affecting the right heart, one alternative option for bioprosthetic intervention is the implantation of a mitral allograft (a donor heart valve) in the position of the tricuspid valve. We present a clinical case detailing the successful implantation of a fresh mitral allograft into the tricuspid position in a 37-year-old male patient diagnosed with active infective endocarditis of the tricuspid valve and a high risk of prosthetic endocarditis. The mitral allograft was anatomically implanted with annuloplasty using an expanded polytetrafluoroethylene band.

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Long-term outcomes of mitral valve repair in children.

Front Cardiovasc Med

October 2024

Department of Cardiovascular Surgery, Faculty of Medicine, Ege University, Izmir, Türkiye.

Article Synopsis
  • Mitral Valve Disease in children is challenging due to varying associated conditions, and repair is preferred over replacement because prosthetic valves can cause complications as children grow.
  • A study analyzed 47 pediatric patients who underwent mitral valve repair from 2002 to 2023, finding a low early mortality rate of 6.3% and encouraging long-term survival rates of 93.6% at one year and 91.4% at ten years.
  • The results suggest that mitral valve repair provides favorable outcomes, with an 85.1% rate of freedom from re-operation at ten years, indicating that individualizing treatment based on patient growth and specific conditions can maximize success.
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Cardiac amyloidosis (CA) is a cardiac storage disease caused by the progressive extracellular deposition of misfolded proteins in the myocardium. Despite the increasing interest in this pathology, it remains an underdiagnosed condition. Non-invasive diagnostic techniques play a central role in the suspicion and detection of CA, also thanks to the continuous scientific and technological advances in these tools.

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: Contactless monitoring of instantaneous heart rate and respiration rate has a significant clinical relevance. This work aims to use Speckle Vibrometry (i.e.

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Pentadecanoic Acid-Releasing PDMS: Towards a New Material to Prevent Biofilm Formation.

Int J Mol Sci

October 2024

Department of Chemical Sciences, University of Naples "Federico II", Complesso Universitario Monte S. Angelo, Via Cintia 4, 80126 Naples, Italy.

Microbial biofilm formation on medical devices paves the way for device-associated infections. is one of the most common strains involved in such infections as it is able to colonize numerous devices, such as intravenous catheters, prosthetic joints, and heart valves. We previously reported the antibiofilm activity against of pentadecanoic acid (PDA) deposited by drop-casting on the silicon-based polymer poly(dimethyl)siloxane (PDMS).

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Infective endocarditis (IE) is a disease associated with significant morbidity and mortality. It is more commonly caused by Gram-positive cocci, but Gram-positive bacilli may seldom cause the disease. is an aerobic Gram-positive coccobacillus and a foodborne and opportunistic pathogen most commonly causing gastrointestinal infections, even though bacteremia, sepsis, meningitis, and fetal infections may also occur.

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Homograft implant for prosthetic aortic endocarditis with paravalvular abscess in a patient with persistent left superior vena cava.

Multimed Man Cardiothorac Surg

October 2024

Department of Cardiothoracic Surgery, Cardiovascular Research Institute-Maastricht University, Universiteitssingel 50, 6229 ER Maastricht, The Netherlands.

Article Synopsis
  • A patient with prosthetic aortic valve endocarditis faced severe complications, necessitating urgent surgery due to significant valve detachment and prior cardiac surgeries.
  • Preoperative imaging uncovered a rare left superior vena cava anomaly, which required special techniques for safe surgery.
  • The surgical procedure involved removing the infected valve and tissue, then replacing it with a cryopreserved aortic homograft for better fit and function.
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Article Synopsis
  • Patients with mechanical heart valves require vitamin K antagonists (VKAs) due to risks of thrombosis and embolism, making proper treatment control crucial.
  • A study during the COVID-19 pandemic showed that fewer patients had regular INR tests and overall time in therapeutic range (TTR) decreased compared to the year before the pandemic.
  • Results indicate that VKA management for these patients worsened during the pandemic, with fewer tests and lower control levels than previously observed.
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Article Synopsis
  • Vascular complications are a significant issue for patients undergoing transfemoral transcatheter aortic valve replacement (TAVR), especially those with peripheral artery disease, and the Hostile score has been developed to help assess risk.
  • A study validated the Hostile score by analyzing data from 2,023 TAVR patients, finding that those with higher Hostile scores were more likely to experience vascular complications, particularly non-puncture site issues.
  • The research found that independent predictors of complications included body mass index, use of specific closure devices, and a higher Hostile score, with the score being particularly effective in predicting non-puncture site complications after the procedure.
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Article Synopsis
  • Infective endocarditis (IE) is a severe complication after valve replacement surgeries, occurring in 1.8% to 5.8% of cases, with up to 20% in-hospital mortality; common pathogens include Streptococci, Staphylococcus aureus, Enterococci, and fungi.
  • The treatment for IE often requires lengthy antibiotic courses, and cases involving aortic prosthetic valves may need complex surgical interventions due to root abscess formations.
  • A recent case series from Greece reported successful outcomes in 8 patients who underwent surgery for prosthetic valve endocarditis with significant aortic root abscesses, highlighting the effectiveness of using aortic homografts for aortic root replacement in these challenging
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Artificial Intelligence Improves Prediction of Major Adverse Cardiovascular Events in Patients Undergoing Transcatheter Aortic Valve Replacement Planning CT.

Acad Radiol

October 2024

Department of Radiology and Radiological Science, Medical University of South Carolina, 25 Courtenay Dr, Charleston, South Carolina 29425, USA (G.T., M.V.N., U.J.S., E.Z., G.J.A., D.K., J.O., P.S.S., I.M.K., T.E., A.V.S.). Electronic address:

Article Synopsis
  • Coronary CT angiography (CCTA) is crucial before transcatheter aortic valve replacement (TAVR), and this study aimed to assess how well AI software can predict major adverse cardiovascular events (MACE) in TAVR patients by analyzing cardiac parameters.
  • The study included 648 patients, revealing that 17.9% experienced MACE within an average follow-up of 24 months, with left ventricle long axis shortening (LV-LAS) identified as a key predictor of MACE after considering other clinical factors.
  • The results showed that the AI-derived LV-LAS significantly improved prediction models for MACE, demonstrating that automated cardiac assessments can effectively aid in risk stratification prior to TAVR procedures
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Article Synopsis
  • Right ventricular dysfunction (RVD) affects 30-40% of patients experiencing acute myocardial infarction and cardiogenic shock, leading to concerns about their survival outcomes when treated with left ventricular mechanical support.
  • A study conducted across 80 sites analyzed 361 patients, finding that 28% had RVD, which correlated with lower survival rates to discharge (61.8% vs. 73.4%) and higher instances of severe shock and active CPR during treatment.
  • Despite initial lower survival for RVD patients, hemodynamic parameters measured within 24 hours showed no significant differences between those with and without RVD, indicating that early left ventricular support may not immediately affect RV function.
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Article Synopsis
  • * Among 239 patients assessed, 124 had RVD, which was linked to factors like lower left ventricular ejection fraction and higher blood urea nitrogen levels, but did not significantly affect certain immediate procedural outcomes.
  • * RVD was found to be a strong predictor of worse long-term outcomes, with higher rates of major adverse cardiac and cerebrovascular events (MACCE) at 90 days and increased mortality at one year post-procedure.
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Article Synopsis
  • Dual antiplatelet therapy helps prevent serious blood clot events in patients with conditions like deep vein thrombosis and after stent placements, but it carries a significant risk of bleeding.
  • One of the most serious risks of this therapy is gastrointestinal bleeding, which accounts for nearly half of major bleeding incidents related to its use.
  • A case is presented involving a 74-year-old woman who experienced lower gastrointestinal bleeding after undergoing dual antiplatelet therapy, and she was successfully treated with an endovascular coil procedure.
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