2 results match your criteria: "Professor and Chair Department of Dermatology University of Connecticut Health Center Farmington[Affiliation]"
Why Biologic Therapies Sometimes Lose Efficacy.
Semin Cutan Med Surg
June 2016
Professor and Chair Department of Dermatology University of Connecticut Health Center Farmington, Connecticut.
Biologic therapies for psoriasis are associated with loss of response over time. Immunogenicity, suboptimal dosing, low serum drug levels, and intermittent or episodic therapy have been documented as explanations for this phenomenon. Use of an immunomodulatory agent can reduce the risk of immunogenicity and improve clinical response.
View Article and Find Full Text PDFNew Therapies for Psoriasis.
Semin Cutan Med Surg
June 2016
Professor and Chair Department of Dermatology University of Connecticut Health Center Farmington, Connecticut.
Among the newer medications for treating psoriasis are the interleukin-17A inhibitor secukinumab and the phosphodiesterase 4 inhibitor apremilast. Secukinumab offers a level of efficacy greater than that of the tumor necrosis factor-α inhibitor adalimumab. Apremilast is associated with lower levels of efficacy than the biologic therapies for psoriasis.
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