627 results match your criteria: "Prof Dr Cemil Tascıoglu Hospital[Affiliation]"

Article Synopsis
  • Dual antiplatelet therapy (DAPT) is essential for managing acute and chronic coronary syndromes, helping to lower mortality rates and prevent further complications.
  • A study followed 1500 patients on a specific fixed-dose DAPT (ASA + clopidogrel) to evaluate its effectiveness and safety, primarily focusing on hospitalization and bleeding risks.
  • Results indicated that the fixed-dose combination therapy was effective, with low rates of hospitalization for cardiovascular issues and minimal bleeding complications in appropriately selected patients.
View Article and Find Full Text PDF

Background: Endovascular treatments are frequently applied in pelvic venous disorders (PeVDs) with guidelines recommendations. There is no clear answer as to which of the embolization methods applied with endovascular treatments is superior. In this study, we aimed to compare the outcomes and symptom relief of patients with PeVDs treated using coils alone versus those treated with both coils and ethylene vinyl alcohol copolymer, as well as to evaluate the material usage and safety and efficacy of these treatments.

View Article and Find Full Text PDF

Acute pancreatitis (AP) is a clinical condition that arises acutely in the pancreas through various inflammatory pathways due to multiple causes. Turkish Society of Gastroenterology Pancreas Working Group developed comprehensive guidance statements regarding the management of AP that include its epidemiology, etiology, clinical presentation, diagnostic criteria, disease severity, treatment, prognosis, local and systemic complications. The statements were developed through literature review, deliberation, and consensus opinion.

View Article and Find Full Text PDF
Article Synopsis
  • The study aimed to evaluate the quality and readability of websites about Piriformis Syndrome by analyzing the top 200 results from a Google search.
  • Out of 138 websites assessed, 39 were deemed high-quality, primarily from scientific and health portals, but there was no significant difference in overall readability between high and low-quality sites except for specific readability scores.
  • The content analysis revealed that scientific websites provided more information about diagnosis, while non-profit sites discussed surgical options the most, highlighting varying content approaches among different types of websites.
View Article and Find Full Text PDF

Purpose: This study aims to evaluate the effectiveness of two prophylactic strategies in preventing shunt infections in pediatric patients undergoing ventriculoperitoneal shunt surgery.

Methods: This retrospective study included pediatric patients who underwent ventriculoperitoneal shunt surgery between 2017 and 2024. Patients were divided into two groups based on the prophylactic method used: Group 1 (VS) where the shunt was washed with vancomycin solution before placement, and Group 2 (TVP) where vancomycin powder was applied to the subgaleal and subcutaneous tissues after shunt placement.

View Article and Find Full Text PDF

Retrospective analysis of hemophilia B in Turkey: identifying main characteristics and treatment options.

Res Pract Thromb Haemost

October 2024

Department of Internal Medicine, Division of Hematology, Istanbul University - Cerrahpasa, Cerrahpasa Faculty of Medicine, Istanbul, Turkey.

Background: Hemophilia B (HB), an X-linked recessive inherited bleeding disorder, exhibits a high prevalence among males.

Objectives: To present the first national cohort of persons with HB to define the demographics, clinical characteristics, and treatment patterns in Turkey.

Methods: This multicenter, retrospective study included 433 alive persons with HB registered in 35 centers between 1961 and 2018.

View Article and Find Full Text PDF

Background: Food allergy is a public health issue that has a significant impact on the lives of families. Parental self-efficacy/confidence is important in managing food allergies. The aim of this study is to validate the "Food Allergy Self-Efficacy Scale for Parents" (FASE-P) and assess parental self-efficacy in managing their child's food allergy.

View Article and Find Full Text PDF
Article Synopsis
  • - In recent years, multipotent mesenchymal stromal cells (MSCs) have emerged as a potential therapy for lung regeneration in preterm infants, suggesting their use could also benefit conditions like pulmonary hypoplasia seen in congenital diaphragmatic hernia.
  • - A case study highlighted a newborn with a left congenital diaphragmatic hernia who received two MSC treatments, resulting in improved respiratory function and nutrition without any side effects.
  • - While MSC therapy shows promise for addressing pulmonary hypoplasia and intestinal issues related to congenital diaphragmatic hernia, further research is needed to understand side effects, optimal dosages, and administration techniques.
View Article and Find Full Text PDF

Background: Diagnosing anaphylaxis in children within the first 2 years of life can be difficult due to the often confusing and nonspecific signs and symptoms.

Objective: This study focuses on the phenotype of anaphylaxis in children within the first 2 years of life and aims to increase awareness of anaphylaxis in this age group.

Methods: The study included children between 0 and 2 years who were diagnosed as having anaphylaxis by pediatric allergists in 11 tertiary hospitals.

View Article and Find Full Text PDF

Background: The etiopathogenesis of seborrheic dermatitis (SD) remains unexplained, although several factors have been considered in this regard.

Objective: The aim of this study is to investigate diet, metabolic status, and oxidative stress in SD patients.

Methods: This prospective, single-center, case-control study included 49 SD patients and 40 gender- and age-matched healthy controls.

View Article and Find Full Text PDF

Background: The aim of this study is to investigate whether vitamin D, calcium, ferritin, and uric acids play a beneficial biomarker role in the prevention of colorectal cancer (CRC) risk.

Methods: The case-control design was employed, including 650 CRC cases and 650 controls aged 35 to 70 years, comprising both men and women. The study encompasses sociodemographic data, clinical information, radiological diagnoses, and biochemical measurements.

View Article and Find Full Text PDF

Background: Critically ill intensive care unit (ICU) patients often face life-threatening drug-related problems (DRPs) and malnutrition. Clinical pharmacists (CPs) play a crucial role in mitigating these issues and improving outcomes.

Aim: This study was designed to detect, prevent, reduce or resolve nutrition-related problems (NRPs) and DRPs in intensive care patients with renal dysfunction through clinical pharmacy services.

View Article and Find Full Text PDF

Introduction: Vasospasm has been reported as the most important cause of mortality and morbidity in patients with subarachnoid haemorrhage (SAH) who can reach the hospital. Matrix metalloproteinases (MMPs) are a gene family, which are called neutral proteases in the central nervous system (CNS). In this experimental study we studied the upregulation of MMPs (MMP-8, MMP-9, and MMP-13) gene expression and the inhibitor effects of doxycycline after experimental SAH model in rats.

View Article and Find Full Text PDF

The involvement of lymph nodes critically affects patient outcomes in prostate cancer. While traditional risk models use factors like stage and PSA levels, the detection of lymph node involvement through modalities like PET targeting PSMA with Ga radiotracer plays a pivotal role in guiding treatments ranging from prostatectomy to pelvic radiotherapy. This study aims to create a deep learning model to predict lymph node involvement in intermediate to high-risk prostate cancer patients using Ga-PSMA PET/CT imagery, radiomics features, and various clinical parameters.

View Article and Find Full Text PDF

Aims: To assess the outcomes of robotic surgery for patients with neurogenic lower urinary tract dysfunctions (NLUTD).

Materials And Methods: Studies evaluating the outcomes (efficacy and safety) of robot-assisted ileal conduit creation or artificial urinary sphincter (R-AUS) implantation or augmentation cystoplasty or continent urinary diversion creation in patients with NLUTD were included. The search strategy and studies selection were performed on Medline, Embase and Cochrane using the PICOS method according to the PRISMA statement (PROSPERO 2022 CRD42022333157).

View Article and Find Full Text PDF

Background: Degeneration of the spine may affect pelvic parameters and hip mobility. This study aimed to evaluate the effects of degenerative scoliosis and spinopelvic parameters on hip hemiarthroplasty dislocations.

Methods: A retrospective analysis was conducted on patients who underwent hemiarthroplasty for intracapsular hip fracture over a twenty-year period.

View Article and Find Full Text PDF
Article Synopsis
  • The study aimed to assess how aware community-dwelling women aged 60 and over are of their pelvic floor muscles and related exercises, and how this awareness relates to urinary incontinence.
  • It included a survey of 500 women, revealing that both knowledge and awareness of pelvic floor muscles and exercises were generally low, especially among those with urinary incontinence.
  • The findings suggest that educational programs are needed to improve understanding and proper practice of pelvic floor muscle exercises in this age group.
View Article and Find Full Text PDF

The Effect of Dexmedetomidine and Levobupivacaine in an Experimental Ischemia Reperfusion Model.

In Vivo

October 2024

Department of General Surgery, Health Science University, Prof. Dr. Cemil Tascioglu, Training, and Research Hospital, Istanbul, Turkey.

Background/aim: Although it has been reported that different molecules are effective in preventing ischemia-reperfusion (I/R) injury, the most effective treatment is still unknown.

Materials And Methods: The rats were divided into four groups of eight rats each. Group C: 1 ml intraperitoneal (IP) isotonic + laparotomy + IP 2 ml isotonic +I/R.

View Article and Find Full Text PDF

Spontaneous Complete Regression of Breast Cancer: Two Case Report.

Ann Ital Chir

October 2024

Department of Pathology, Prof. Dr. Cemil Tascioglu City Hospital, University of Health Sciences, 34384 Istanbul, Türkiye.

Article Synopsis
  • - Spontaneous regression (SR) refers to the unexpected reduction or disappearance of a tumor without treatment, but it is rare in both breast cancer and other cancer types.
  • - The study included two cases of SR but lacked sufficient evidence to clarify the underlying mechanisms, and neither patient showed PD-L1, contradicting its proposed antitumoral role.
  • - One patient was the first documented case with Cerb B2 positivity and an early SR period, suggesting that thorough examinations before surgery could increase SR occurrences in breast cancer and aid in understanding the underlying mechanisms.
View Article and Find Full Text PDF

Aim: This study aimed to investigate the causes and risk factors of colorectal cancer (CRC) in a Turkish population, focusing on various modifiable and non-modifiable risk factors.

Methods: A hospital-based case-control design was employed to compare individuals with CRC (cases) to individuals without CRC (controls). Male and female participants were recruited from the surgery, internal medicine, and out-patient departments.

View Article and Find Full Text PDF

: Ceftazidime-avibactam (CAZ-AVI) is recommended as first-line treatment for Oxacillinase-48 (OXA-48) β-Lactamase-producing carbapenem-resistant Enterobacterales (CRE) infections, while polymyxin-based combination therapies (PBCTs) are used as a last resort when CAZ-AVI is unavailable. Research comparing the effectiveness of CAZ-AVI and PBCT in CRE blood stream infections (CRE-BSIs) is limited, mostly focusing on carbapenemase (KPC)-producing isolates. In Turkey, OXA-48 is endemic and OXA-48-Like is common.

View Article and Find Full Text PDF

Background: The COVID-19 vaccination campaign in several European countries involved collaboration between public health and Primary Health Care (PHC).

Objective: To highlight the role of PHC professionals in the COVID-19 vaccination rollout, specifically in terms of vaccine administration, communication and contributing to vaccination population coverage.

Methods: A descriptive retrospective study of the COVID-19 vaccination campaign across 28 European countries was conducted, covering data from December 2020 to November 2021.

View Article and Find Full Text PDF