4 results match your criteria: "Private Hospital Sainte Marie[Affiliation]"

Implementation and use of whole exome sequencing for metastatic solid cancer.

EBioMedicine

January 2020

Department of Medical Oncology, Georges François Leclerc Cancer Center - UNICANCER, 1 rue Professeur Marion, Dijon 21000, France; Platform of Transfer in Cancer Biology, Georges François Leclerc Cancer Center - UNICANCER, Dijon, France; Université Bourgogne Franche-Comté, Dijon, France; Genomic and Immunotherapy Medical Institute, Dijon, France; INSERM U1231, Dijon, France. Electronic address:

Background: Genomically-guided clinical trials are performed across different tumor types sharing genetic mutations, but trial organization remains complex. Here we address the feasibility and utility of routine somatic and constitutional exome analysis in metastatic cancer patients.

Methods: Exoma trial (NCT02840604) is a multicenter, prospective clinical trial.

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Retrospective study on the management and follow-up of 18 patients with a mid-urethral sling penetrating the urethra or bladder.

J Gynecol Obstet Hum Reprod

September 2018

Department of Urology, Private Hospital Sainte Marie, Ramsay General de Santé, 4 allée Saint Jean des Vignes, 71100 Chalon-sur-Saône, France.

Article Synopsis
  • The mid-urethral sling (MUS) is the most common surgical treatment for stress urinary incontinence (SUI), but complications like bladder or urethral sling exposure can occur, requiring surgical management.
  • A study on 18 women revealed various cases of sling exposure, classified by severity, confirmed through flexible urethro-cystoscopy, and treated with surgical removal of eroded materials.
  • After follow-up, 17 out of 18 patients showed no sling exposure, and many reported improved urologic comfort, with some requiring multiple surgical procedures to address complications.
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Objective: To evaluate the feasibility, efficacy, complications, and outcomes of treatment of anterior or central compartment urogenital prolapse by placement of an anteroposterior 22-g/m(2) mesh with six straps through one anterior vaginal incision.

Methods: In a prospective study, patients treated for urogenital prolapse at a center in France between February 2008 and June 2011 were enrolled. Previous treatments, related interventions, intraoperative and postoperative complications, and anatomic outcomes were recorded during 3years of follow-up.

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