Seasonal influenza in children: complications, treatment, prevention (subject publication review).

Objective: Aim: To study the specificity of seasonal flu in children, in particular, in young children, as well as treatment, prevention and complications of seasonal flu.

Patients And Methods: Materials and Methods: For the methodological justification of the article, we used the pool of research technologies. Methods of theoretical analysis, system-analytical, comparative methods provided us with the opportunity to characterize the features of influenza incidence in children.

CLINICAL AND EPIDEMIOLOGICAL FEATURES OF COVID-19 IN CHILDREN FOR THE PERIOD 2020-2022.

Objective: The aim: To investigate the epidemiological and clinical characteristics of COVID-19 in children for the period 2020-2022.

Patients And Methods: Materials and methods: A retrospective analysis of 1144 case histories of children who were hospitalized at the St. Zinaida Children's Clinical Hospital (Sumy, Ukraine) for coronavirus disease for 2020-2022 was carried out.

EBV-ENCEPHALITIS IN CHILDREN: DIAGNOSTIC CRITERIA.

Objective: The aim: To investigate the clinical characteristics of EBV infection in the pediatric nervous system using laboratory methods and brain MRI data.

Patients And Methods: Materials and methods: We observed 41 children with EBV encephalitis ranging from 8 months to 17 years old. The diagnosis of EBV-encephalitis was established on the basis of clinical and medical history, laboratory and instrumental (brain MRI) data.

FEATURE OF GUT MICROBIOTA IN PATIENTS WITH MIGRAINE AND HEALTHY INDIVIDUALS.

The gut - brain axis plays a significant role in the pathophysiology of migraine. This interaction can be influenced by multiple factors, such as gut microbiota profiles. The aim of the study was to analyze the gut microbiome state in patients with migraine and healthy individuals, to assess possible correlations between the detected changes in patients with migraine and the frequency, intensity of headaches, their psycho-emotional state, and quality of life.

Prevalence of health care-associated infections and antimicrobial resistance of the responsible pathogens in Ukraine: Results of a multicenter study (2014-2016).

Background: The aim of this study was to obtain the first national estimates of the current prevalence and incidence and death of health care-associated infections (HAIs) of all types in acute care hospitals in Ukraine.

Methods: Prospective surveillance was conducted from January 2014 to December 2016 in 17 hospitals. Surveillance case definitions were derived from the Centers for Disease Control and Prevention's National Healthcare Safety Network HAI case definitions.

Association between depressive symptoms and cognitive impairment in patients with metabolic syndrome.

Introduction: Metabolic dysregulation is intimately associated with wide array of seemingly unrelated disorders, including cognitive impairment and depression. The aim was: to identify special characteristic features of depressive disorder in patients with metabolic syndrome (Mets); to identify possible association between depressive disorder (DD) and cognitive impairment in patients with Mets; to establish whether metabolic syndrome and its components are associated with severity of DD.

Materials And Methods: The study group consisted of 108 patients with depressive disorders aged from 45 to 84 years.