56 results match your criteria: "Prism Eye Institute[Affiliation]"

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Ophthalmology

December 2024

John A. Moran Eye Center, University of Utah, Salt Lake City, Utah; Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Ontario, Canada; Prism Eye Institute, Mississauga, Canada. Electronic address:

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Ophthalmology

November 2024

John A. Moran Eye Center, University of Utah, Salt Lake City, Utah; Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Ontario, Canada; Prism Eye Institute, Mississauga, Canada. Electronic address:

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Topic: To examine the association between virtual postoperative follow-up care and patient outcomes after cataract surgery.

Clinical Relevance: Cataract surgery is a safe and commonly performed surgery. Follow-up visits are used to monitor for complications.

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Comparative Effects of Glucagon-like Peptide 1 Receptor Agonists and Metformin on Glaucoma Risk in Patients with Type 2 Diabetes.

Ophthalmology

August 2024

Department of Ophthalmology and Vision Sciences, John A. Moran Eye Center, University of Utah, Salt Lake City, Utah; Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Canada; Prism Eye Institute, Mississauga, Canada. Electronic address:

Purpose: To compare effects of glucagon-like peptide 1 (GLP-1) receptor agonists and metformin on the risk of primary open-angle glaucoma (POAG), ocular hypertension, and the need for first-line glaucoma treatments in patients with type 2 diabetes mellitus (T2DM).

Design: A retrospective cohort study was conducted using electronic medical records data from an international electronic health record network, covering a period from May 2006-2024.

Participants: Patients with a diagnosis of T2DM who were treated with either GLP-1 receptor agonists or metformin.

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To review the latest surgical advances and evolving clinical use of scleral bio-tissue for reinforcement in the eye and review the published literature on novel surgical applications of scleral allograft bio-tissue. Conventional surgical procedures for scleral reinforcement using homologous scleral allograft have been traditionally ab-externo interventions comprising of anterior or posterior reinforcement of the sclera for clinical indications such as trauma, scleromalacia, glaucoma drainage device coverage, scleral perforation, buckle repair as well as posterior reinforcement for pathologic myopia and staphyloma. There have been a few novel ab-interno uses of scleral bio-tissue for reinforcement in both retina and glaucoma.

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Mitomycin C 0.2 mg/ml versus Mitomycin C 0.4 mg/ml during the Implantation of an Ab Externo Polystyrene-isobutylene-styrene Microshunt: A Mega-analysis.

Ophthalmol Glaucoma

September 2024

John A. Moran Eye Center, University of Utah, Salt Lake City, Utah; Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Canada; Prism Eye Institute, Mississauga, Canada.

Purpose: To compare the effectiveness and adverse event profile of standalone polystyrene-isobutylene-styrene (SIBS) microshunt implantation with adjunct mitomycin C (MMC) 0.2 mg/ml and MMC 0.4 mg/ml.

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Purpose: Risk communication is an integral aspect of shared decision-making and evidence-based patient choice. There is currently no recommended way of communicating risks and benefits of cataract surgery to patients. This study aims to investigate whether the way this information is presented influences patients' perception of how risky surgery will be.

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Objective: In a world where digital media is deeply engrained into our everyday lives, there lies an opportunity to leverage interactions with technology for health and wellness. The Vision Performance Index (VPI) leverages natural human-technology interaction to evaluate visual function using visual, cognitive, and motor psychometric data over 5 domains: field of view, accuracy, multitracking, endurance, and detection. The purpose of this study was to describe a novel method of evaluating holistic visual function through video game-derived VPI score data in patients with specific ocular pathology.

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Purpose: Iris pigment deficiency in patients with oculocutaneous albinism (OCA) often causes debilitating photophobia, which is routinely managed by sequential intracapsular insertion of two aniridia rings. A common concern of this technique is the risk of segment interdigitation, which can lead to intraoperative complications.

Observations: In this report, we describe a modified technique through which both rings were stacked together and inserted simultaneously in a 62-year-old male patient with oculocutaneous albinism and a mild cataract.

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New Devices in Glaucoma.

Ophthalmol Ther

October 2023

Department of Ophthalmology, Scheie Eye Institute, University of Pennsylvania Perelman School of Medicine, 51 North 39th St., Philadelphia, PA, 19104, USA.

Glaucoma remains a leading cause of blindness globally. Minimally invasive treatment techniques are rapidly expanding the availability of therapeutic options for glaucoma. These include devices aimed at enhancing outflow through the subconjunctival space, Schlemm's canal, and suprachoroidal space, sustained-release drug delivery devices, and extraocular devices aiming to reduce glaucomatous progression through other novel means.

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All Consecutive Ab Externo SIBS Microshunt Implantations With Mitomycin C: One-Year Outcomes and Risk Factors for Failure.

Am J Ophthalmol

November 2023

From the Department of Ophthalmology and Vision Sciences (M.B.S., J.J.A.,I.I.K.A.), University of Toronto, Toronto, Ontario, Canada; Prism Eye Institute (M.B.S., J.J.A., I.I.K.A.), Mississauga, Ontario, Canada; John A. Moran Eye Center (M.B.S., T.D.F., I.I.K.A.), University of Utah, Salt Lake City, Utah, USA.

Purpose: To present the effectiveness, risk factors for surgical failure, and adverse events over 12 months in a consecutive diverse cohort of glaucoma patients who underwent solo or combined ab externo SIBS microshunt with mitomycin C (MMC) with or without previous subconjunctival surgery.

Design: Retrospective, consecutive, interventional case series.

Methods: Consecutive glaucomatous eyes on maximally tolerated medical therapy received ab externo SIBS microshunt with MMC implantation as a solo or combined procedure with phacoemulsification from July 2015 to January 2020.

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Introduction: The unmet need for remote monitoring of visual function with home-based, patient-centric technologies became increasingly palpable during the COVID-19 pandemic. Many patients with chronic eye conditions lack access to office-based examinations. Here, we evaluate the efficacy of the Accustat® test, a virtual application for measuring near visual acuity on any portable electronic device via telehealth.

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Intermediate Outcomes of the Novel 63-μm Gelatin Microstent versus the Conventional 45-μm Gelatin Microstent.

Ophthalmol Glaucoma

November 2023

Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Canada; Prism Eye Institute, Mississauga, Canada; John A. Moran Eye Center, University of Utah, Salt Lake City, Utah.

Purpose: To determine intermediate intraocular pressure (IOP)-lowering and adverse event profile of the 63-μm gelatin microstent (Xen63) with mitomycin C (MMC) compared with the 45-μm gelatin microstent (Xen45) with MMC.

Design: Single center, consecutive, retrospective cohort study.

Participants: Eighty-four glaucomatous eyes (42 63-μm gelatin microstent and 42 45-μm gelatin microstent) with or without previous subconjunctival glaucoma surgery.

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Ab Externo SIBS Microshunt with Mitomycin C for Open-Angle Glaucoma: Three-Year Results as a Primary Surgical Intervention.

Ophthalmol Glaucoma

November 2023

Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Canada; Prism Eye Institute, Mississauga, Canada; John A. Moran Eye Center, University of Utah, Salt Lake City, Utah.

Purpose: To determine the effectiveness, risk factors for surgical failure, and adverse events in a large cohort of patients receiving stand-alone ab externo poly(styrene-block-isobutylene-block-styrene) (SIBS) microshunt implantation with mitomycin C (MMC) over 3 years of follow-up.

Design: Retrospective, interventional case series.

Participants: Glaucomatous eyes on maximally tolerated medical therapy with no previous subconjunctival glaucoma surgery.

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Background: Although traditional surgical procedures for glaucoma (such as trabeculectomy and tube-shunt implantation) can significantly reduce intraocular pressure (IOP), they are associated with numerous complications, some of which are vision-threatening, or involve prolonged recovery or a highly intensive postoperative course. Micro-invasive glaucoma surgery (MIGS) procedures have shown better safety but reduced efficacy in achieving target IOP. Combinations of these methods have led to the development of subconjunctival micro-invasive procedures with safety comparable to traditional surgery and greater efficacy than minimally invasive methods.

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The Cataract Surgery Learning Curve: Quantitatively Tracking a Single Resident's Operative Actions Throughout Their Training.

Am J Ophthalmol

May 2023

Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Ontario, Canada (J.M.K., A.R., A.R., I.I.K.A., M.B.S.); Kensington Eye Institute, Toronto, Ontario, Canada (J.M.K., A.R., A.R., I.I.K.A., M.B.S.); Prism Eye Institute, Mississauga, Ontario, Canada (A.R., A.R., I.I.K.A., M.B.S.). Electronic address:

Purpose: To track operative phases of cataract surgery over a resident's training to measure action times and frequencies as a surrogate for competency and skill progression.

Design: An n = 1 panel study.

Methods: Cataract surgery video recordings performed by a single resident between 2021-2022 were collected.

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Introduction: There is significant unmet need for patient-centric remote monitoring of visual function for chronic retinal diseases, as demonstrated by the COVID-19 pandemic. The Macustat® central retinal function scan is a novel cloud-based digital health application for remote monitoring. The aim of this study is to assess the efficacy of the Macustat® compared to traditional in-office retinal evaluations.

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Purpose: To determine the change in Humphrey visual field and clinical parameters after minimally invasive glaucoma surgery combined with cataract surgery.

Patients And Methods: Patients undergoing minimally invasive glaucoma surgery combined with cataract surgery in a multicenter retrospective case series between 2013 and 2021 with reliable preoperative and 12 to 18 month postoperative visual field measurements were included. Devices included iStent, XEN, and Hydrus.

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Purpose: To assess practice patterns and opinions of glaucoma specialists regarding glaucoma drainage device tube shunt placement and post-operative anti-inflammatory medication use. We also assess the perceived need for a randomized control trial to compare them.

Patients And Methods: An online survey was distributed to a group of glaucoma specialists from the American Glaucoma Society via the American Glaucoma Society forum from April to August 2021.

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Ontario Cataract Quality Outcome Initiative: appropriateness and prioritization of cataract surgery.

Can J Ophthalmol

August 2023

Kensington Eye Institute, Toronto, ON; Department of Ophthalmology and Vision Science, University of Toronto, Toronto, ON.

Objective: To explore the utility of the Catquest 9SF visual function (VF) questionnaire along with visual acuity (VA) for determining appropriateness and priority for cataract surgery. To evaluate the feasibility of administering the Catquest-9SF in a clinical setting using web-based electronic data capture and interpretation.

Design: Prospective multicentred interventional observational study.

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Development and validation of the Iris Glare, Appearance, and Photophobia questionnaire for patients with iris defects.

J Cataract Refract Surg

October 2022

From the Section of Ophthalmology, Department of Surgery, University of Calgary, Eye Clinic, Rockyview General Hospital, Calgary, AB, Canada (Kryshtalskyj); Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, ON, Canada (Rai, Ahmed); Département d'Ophtalmologie, Université de Montréal, Montréal, QC, Canada (Durr); Prism Eye Institute, Oakville, ON, Canada (Ahmed).

Purpose: To validate the Iris Glare, Appearance, and Photophobia (Iris GAP) questionnaire, a new symptom-based and appearance-based quality-of-life measure for patients with iris defects.

Setting: Single tertiary glaucoma clinic in Toronto, Ontario, Canada.

Design: Prospective cohort study.

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Multicenter Comparison of the Toronto Portable Perimeter with the Humphrey Field Analyzer: A Pilot Study.

Ophthalmol Glaucoma

April 2022

Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Ontario, Canada; York Finch Eye Associates, Toronto, Ontario, Canada. Electronic address:

Purpose: To evaluate the agreement between glaucomatous 24-2 visual field (VF) testing performed with the Toronto Portable Perimeter (TPP; VEM Medical Technologies) and the Humphrey Field Analyzer (HFA; Carl Zeiss Meditec).

Design: Multicenter prospective cohort analysis.

Participants: Patients with suspected or confirmed glaucoma treated at Prism Eye Institute (Oakville, Canada), York Finch Eye Associates (North York, Canada), or the Ontario Mobile Medical Eye Care Unit (Cochrane, Canada) between March 2019 and March 2020.

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Multicountry clinical outcomes of a new nondiffractive presbyopia-correcting IOL.

J Cataract Refract Surg

February 2022

From PersonalEyes, Sydney, Australia (Bala); Miranza IOA Madrid Innova Ocular, Madrid, Spain (Poyales); OMIQ-Hospital General de Catalunya, Barcelona, Spain (Guarro); Hospital General de Granollers, Granollers, Spain (Guarro); Oftalvist CIO Jerez, Puerta del Sur Hospital, Cádiz, Spain (Mesa); Imperial College Healthcare NHS Trust & Ophthalmic Consultants of London, London, United Kingdom (Mearza); Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Ontario, Canada (Varma); Prism Eye Institute, Oakville, Ontario, Canada (Varma); Trillium Health Partners, Mississauga, Ontario, Canada (Varma); Alcon Laboratories, Inc., Fort Worth, Texas (Jasti, Lemp-Hull).

Purpose: To evaluate the effectiveness and safety of a new presbyopia-correcting intraocular lens (IOL) with a nondiffractive design, DFT015, compared with an aspheric monofocal IOL, SN60WF.

Setting: 19 investigational sites in 4 countries: Australia, Canada, Spain, and the United Kingdom.

Design: Prospective, randomized, parallel-group, controlled, assessor- and patient-masked clinical study.

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Background/aims: Determine the association between physician-deemed and patient-reported appropriateness and prioritization for cataract surgery.

Methods: Prospective cohort study of 471 patients of 7 ophthalmologists referred for cataract surgery. Ophthalmologists rated patients for cataract surgery appropriateness and prioritization using a visual analogue scale of 0-10 preoperatively.

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Surgeon Experience as a Risk Factor for Short-Term Failure for Ab Interno Gelatin Microstent: A Canadian Multicenter Propensity-Matched Study.

Ophthalmol Glaucoma

April 2022

Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Canada; Prism Eye Institute, Mississauga, Canada. Electronic address:

Purpose: To compare the efficacy and safety of early versus later ab interno gelatin microstent placement with mitomycin C.

Design: Canada-wide, multicenter, retrospective propensity score-matched cohort study.

Participants: Two hundred seventy eyes (135 early cases and 135 later cases) with no prior incisional surgery.

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