314 results match your criteria: "Principality of Liechtenstein; Drexel University College of Medicine[Affiliation]"
Front Physiol
June 2022
Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Molecules
June 2022
Institute for Breath Research, University of Innsbruck, 6850 Dornbirn, Austria.
In vitro studies can help reveal the biochemical pathways underlying the origin of volatile indicators of numerous diseases. The key objective of this study is to identify the potential biomarkers of gastric cancer. For this purpose, the volatilomic signatures of two human gastric cancer cell lines, AGS (human gastric adenocarcinoma) and SNU-1 (human gastric carcinoma), and one normal gastric mucosa cell line (GES-1) were investigated.
View Article and Find Full Text PDFCancers (Basel)
June 2022
Department of Surgery, Paracelsus Medical University/Salzburger Landeskliniken (SALK), 5020 Salzburg, Austria.
Background: Robotic surgery represents a novel approach for the treatment of colorectal cancers and has been established as an important and effective method over the last years. The aim of this work was to evaluate the effect of a robotic program on oncological findings compared to conventional laparoscopic surgery within the first three years after the introduction.
Methods: All colorectal cancer patients from two centers that either received robotic-assisted or conventional laparoscopic surgery were included in a comparative study.
Osteoporos Int
August 2022
Agency for Preventive and Social Medicine, Rheinstr. 61, 6900, Bregenz, Austria.
Biomedicines
June 2022
Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Auenbruggerplatz 15, 8036 Graz, Austria.
Background and Objective: Small, dense low-density lipoproteins (LDLs) are considered more atherogenic than normal size LDLs. However, the measurement of small, dense LDLs requires sophisticated laboratory methods, such as ultracentrifugation, gradient gel electrophoresis, or nuclear magnetic resonance. We aimed to analyze whether the LDL apolipoprotein B (LDLapoB)-to-LDL cholesterol (LDLC) ratio is associated with cardiovascular mortality and whether this ratio represents a biomarker for small, dense LDLs.
View Article and Find Full Text PDFBMJ Open
June 2022
Dr Risch Medical Laboratory, Vaduz, Liechtenstein
Objectives: We investigated machinelearningbased identification of presymptomatic COVID-19 and detection of infection-related changes in physiology using a wearable device.
Design: Interim analysis of a prospective cohort study.
Setting, Participants And Interventions: Participants from a national cohort study in Liechtenstein were included.
Sci Rep
June 2022
Vorarlberg Institute for Vascular Investigation and Treatment (VIVIT), Carinagasse 47, 6800, Feldkirch, Austria.
Serum glypican-4 (GPC4) has been identified as an insulin-sensitizing adipokine serving as a marker for body mass index and insulin resistance in humans. The association of circulating GPC4 with kidney function is to date largely unexplored. Therefore, we aimed to evaluate the association between serum GPC4 and prevalent as well future kidney function in a prospective cohort study.
View Article and Find Full Text PDFPharmacy (Basel)
April 2022
Kantonsspital St. Gallen, 9007 St. Gallen, Switzerland.
Seasonal influenza vaccination rates among European countries remain low despite the World Health Organization's recommendations to vaccinate high-risk groups. Healthcare worker recommendations are strong predictors of increased vaccination uptake in the population. Therefore, this study aimed to analyze seasonal influenza vaccination recommendation behavior among pharmacists towards high-risk groups including patients, coworkers, and pharmacists' family members during the COVID-19 pandemic.
View Article and Find Full Text PDFObjectives: Austria, and particularly its westernmost federal state Vorarlberg, developed an extremely high incidence rate during the COVID-19 pandemic. Healthcare workers (HCWs) worldwide are known to have an increased risk of contracting the disease within the working environment and, therefore, the seroprevalence in this population is of particular interest. We thus aimed to analyse SARS-CoV-2-specific antibody dynamics in Vorarlberg HCWs.
View Article and Find Full Text PDFJ Clin Med
April 2022
Department of General and Thoracic Surgery, Academic Teaching Hospital Feldkirch, 6800 Feldkirch, Austria.
Background: There is a rapidly growing literature available on right hemicolectomy comparing the short- and long-term outcomes of robotic right colectomy (RRC) to that of laparoscopic right colectomy (LRC). The aim of this meta-analysis is to revise current comparative literature systematically. Methods: A systematic review of comparative studies published between 2000 to 2021 in PubMed, Scopus and Embase was performed.
View Article and Find Full Text PDFBMC Microbiol
May 2022
Dr Risch, 3097, Liebefeld, Switzerland.
Background: 16S rDNA-PCR for the identification of a bacterial species is an established method. However, the DNA extraction reagents as well as the PCR reagents may contain residual bacterial DNA, which consequently generates false-positive PCR results. Additionally, previously used methods are frequently time-consuming.
View Article and Find Full Text PDFThis data article is associated to the research article titled 'Serum glypican-4 is a marker of future vascular risk and mortality in coronary angiography patients' (Muendlein et al., 2022). The present article provides additional prospective data on the association of serum glypican-4 (GPC4) with the incidence of future major adverse cardiovascular events (MACE), vascular mortality, and overall mortality in a cohort of 760 coronary angiography patients.
View Article and Find Full Text PDFBMJ Open Qual
April 2022
Department of Biostatistics, Bioinformatics and Biomathematics, Georgetown University, Washington, DC, USA.
Transfusion
April 2022
Australian Red Cross Lifeblood, Brisbane, Queensland, Australia.
Clin Chim Acta
June 2022
Department of Neurology, State Hospital of Rankweil, Academic Teaching Hospital, Rankweil, Austria.
Background And Aims: The potential of disease-modifying therapies for Alzheimer's disease has greatly stimulated interest in the development of minimally invasive testing for early identification of at-risk individuals. Accordingly, identification of blood-based biomarkers is paramount. The recent discovery of plasma phosphorylated at threonine217 (p-tau217) may provide a turning point in Alzheimer's disease detection.
View Article and Find Full Text PDFTransfus Med Hemother
February 2022
German Red Cross Blood Service NSTOB, Springe, Germany.
Clin Chem Lab Med
May 2022
Medical Central Laboratories, Feldkirch, Austria.
Commun Biol
February 2022
Department of Microbiology and Immunology, University of Otago, Dunedin, New Zealand.
Increasing antimicrobial resistance compels the search for next-generation inhibitors with differing or multiple molecular targets. In this regard, energy conservation in Mycobacterium tuberculosis has been clinically validated as a promising new drug target for combatting drug-resistant strains of M. tuberculosis.
View Article and Find Full Text PDFAtherosclerosis
March 2022
Vorarlberg Institute for Vascular Investigation and Treatment VIVIT, Feldkirch, Austria; Private University of the Principality of Liechtenstein, Triesen, Liechtenstein; Department of Medicine and Cardiology, Academic Teaching Hospital Bregenz, Bregenz, Austria; Drexel University College of Medicine, Philadelphia, PA, USA.
Background And Aims: Glypican-4 (GPC4) is a cell surface protein, but can be released into circulation under various clinical conditions. The association of circulating GPC4 with the risk of future cardiovascular events or death is unclear. In the present study, we aimed to investigate the association between serum GPC4 and major adverse cardiovascular events (MACE), vascular mortality, and all-cause mortality in a prospective cohort study.
View Article and Find Full Text PDFSci Adv
February 2022
Department of Life Sciences, Imperial College London, Exhibition Road, London SW7 2AZ, UK.
The global spread of multidrug-resistant infections urgently calls for the identification of novel drug targets. We solved the electron cryo-microscopy structure of the FF-adenosine 5'-triphosphate (ATP) synthase from in three distinct conformational states. The nucleotide-converting F subcomplex reveals a specific self-inhibition mechanism, which supports a unidirectional ratchet mechanism to avoid wasteful ATP consumption.
View Article and Find Full Text PDFJ Water Health
January 2022
Department of Microbiology, Universität Innsbruck, Technikerstraße 25d, Innsbruck 6020, Austria E-mail:
The new coronavirus 2 (SARS-CoV-2) is known to be also shed through feces, which makes wastewater-based surveillance possible, independent of symptomatic cases and unbiased by any testing strategies and frequencies. We investigated the entire population of the Principality of Liechtenstein with samples from the wastewater treatment plant Bendern (serving all 39,000 inhabitants). Twenty-four-hour composite samples were taken once or twice a week over a period of 6 months from September 2020 to March 2021.
View Article and Find Full Text PDFData Brief
February 2022
Vorarlberg Institute for Vascular Investigation and Treatment (VIVIT), Carinagasse 47, Feldkirch AT-6800, Austria.
We investigated 180 consecutive patients with congestive heart failure (CHF), of whom 83 had type 2 diabetes (T2DM) and 97 did not have diabetes as well as 223 controls without CHF, of whom 39 had T2DM and 184 did not have diabetes. Data was recorded by standardized interviews and by standardized examination protocols at our institution and were extracted from medical records. Here, we analyzed data on gender differences.
View Article and Find Full Text PDFLangenbecks Arch Surg
May 2022
Department of General and Thoracic Surgery, Academic Teaching Hospital, Carinagasse 47, A-6800, Feldkirch, Austria.
Purpose: Umbilical midline incisions for single incision- or reduced port laparoscopic surgery are still discussed controversially because of a higher rate of incisional hernia compared to conventional laparoscopic techniques. The aim of this study was to evaluate incidence and risk factors for incisional hernia after reduced port colorectal surgery.
Methods: A total 241 patients underwent elective reduced port colorectal surgery between 2014 and 2020.
Osteoporos Int
June 2022
Agency for Preventive and Social Medicine, Bregenz, Austria.
Unlabelled: The association of serum gamma-glutamyl-transferase (GGT) with hip fracture risk has not been examined in women and men ≥ 50 years. We show that elevated GGT was associated with increased hip fracture risk, particularly in men. GGT could be a candidate serum marker of long-term hip fracture risk in the elderly.
View Article and Find Full Text PDFAtherosclerosis
January 2022
Institute of Clinical Chemistry, University Hospital Zurich, University of Zurich, Zurich, Switzerland. Electronic address:
Background And Aims: Apolipoprotein D (apoD) is a lipocalin exerting neuroprotective effects. However, the relevance of apoD in respect to cardiovascular risk is largely unexplored. Therefore, this study aimed to evaluate the ability of apoD to predict future all-cause mortality, cardiovascular mortality, and cardiovascular events.
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