72 results match your criteria: "Princess Norah Bint Abdulrahman University[Affiliation]"

The control charts are frequently employed in process monitoring to assess the average and variability of a process, assuming a normal distribution. However, it is worth noting that some process distributions tend to exhibit a positively skewed distribution, such as the lognormal distribution. This article proposed a maximum exponential weighted moving average control chart for joint monitoring of mean and variance under a lognormal process.

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Introduction: The aim of this study was to systematically review the benefits and harms of using a high-flow nasal cannula (HFNC) for weaning continuous positive airway pressure (CPAP) support in preterm infants.

Methods: Cochrane Central, EMBASE, Medline, and Web of Science were searched from inception to July 15, 2023. Randomised clinical trials (RCTs) comparing weaning CPAP using HFNC versus weaning CPAP alone and evaluating predefined outcomes were included.

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Background: Gestational diabetes mellitus (GDM) is a subtype of diabetes that is discovered during pregnancy and may disappear after puerperium. It has an impact on the well-being of expectant mothers and fetuses. Many women have a poor level of knowledge regarding GDM, especially regarding risk factors, diagnosis, and the role of insulin in the management.

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Introduction Vulvoplasty, or female genital cosmetic surgery (FGCS), refers to any surgical alteration of the vaginal or labial anatomy for aesthetic or medical reasons. It aims to restore or enhance the female genitals and can involve multiple procedures such as labiaplasty, clitoral unhooding, monsplasty, vaginoplasty, hymenoplasty, G-spot augmentation, frenuloplasty, perineoplasty, fat injections, or a combination of these. Labiaplasty is currently the most popular procedure among patients.

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Despite the effectiveness of current vaccines in reducing the spread and severity of SARS-CoV-2 infections, many people, including migrants, refugees, and foreign workers, are hesitant to be vaccinated. This systematic review and meta-analysis (SRMA) was conducted to determine the pooled prevalence estimate of the acceptance and hesitancy rates of the COVID-19 vaccine among these populations. A comprehensive search of the peer-reviewed literature indexed in PubMed, Scopus, Science Direct, and Web of Science databases was conducted.

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Cardiovascular diseases prediction by machine learning incorporation with deep learning.

Front Med (Lausanne)

April 2023

Unit of Biochemistry, Centre of Excellence for Biomaterials Engeneering, Faculty of Medicine, AIMST University, Semeleing, Bedong, Malaysia.

It is yet unknown what causes cardiovascular disease (CVD), but we do know that it is associated with a high risk of death, as well as severe morbidity and disability. There is an urgent need for AI-based technologies that are able to promptly and reliably predict the future outcomes of individuals who have cardiovascular disease. The Internet of Things (IoT) is serving as a driving force behind the development of CVD prediction.

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Updates on Epstein-Barr Virus (EBV)-Associated Nasopharyngeal Carcinoma: Emphasis on the Latent Gene Products of EBV.

Medicina (Kaunas)

December 2022

Department of Medical Microbiology and Parasitology, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian 16150, Kelantan, Malaysia.

Nasopharyngeal carcinoma (NPC) is an uncommon type of malignancy/cancer worldwide. However, NPC is an endemic disease in southeast Asia and southern China and the reasons behind the underlying for such changes are unclear. Even though the Epstein-Barr infection (EBV) has been suggested as an important reason for undistinguishable NPC, the EBV itself is not adequate to source this type of cancer.

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In recent years, we are facing the challenge of drug resistance emergence in fungi. The availability of limited antifungals and development of multi-drug resistance in fungal pathogens has become a serious concern in the past years in the health sector. Although several cellular, molecular, and genetic mechanisms have been proposed to explain the drug resistance mechanism in fungi, but a complete understanding of the molecular and genetic mechanisms is still lacking.

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Genetic Variants and Protective Immunity against SARS-CoV-2.

Genes (Basel)

December 2022

Administration of Pharmaceutical Care, Al-Ahsa Health Cluster, Ministry of Health, Al-Ahsa 31982, Saudi Arabia.

The novel coronavirus-19 (SARS-CoV-2), has infected numerous individuals worldwide, resulting in millions of fatalities. The pandemic spread with high mortality rates in multiple waves, leaving others with moderate to severe symptoms. Co-morbidity variables, including hypertension, diabetes, and immunosuppression, have exacerbated the severity of COVID-19.

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Background: Tixagevimab/cilgavimab (TGM/CGM) are neutralizing monoclonal antibodies (mAbs) directed against different epitopes of the receptor-binding domain of the SARS-CoV-2 spike protein that have been considered as pre-exposure prophylaxis (PrEP). Objectives: This study seeks to assess the efficacy and safety of TGM/CGM to prevent COVID-19 in patients at high risk for breakthrough and severe SARS-CoV-2 infection who never benefited maximally from SARS-CoV-2 vaccination and for those who have a contraindication to SARS-CoV-2 vaccines. Design: This study is a systematic review and meta-analysis.

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Estimated cost of treating hospitalized COVID-19 patients in Saudi Arabia.

Sci Rep

December 2022

Molecular Diagnostics Laboratory, Johns Hopkins Aramco Healthcare, Dhahran, Saudi Arabia.

The economic impact of the COVID-19 pandemic on global health systems is a major concern. To plan and allocate resources to treat COVID-19 patients and provide insights into the financial sustainability of healthcare systems in fighting the future pandemic, measuring the costs to treat COVID-19 patients is deemed necessary. As such, we conducted a retrospective, real-world observational study to measure the direct medical cost of treating COVID-19 patients at a tertiary care hospital in Saudi Arabia.

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As medical science and technology progress towards the era of "big data", a multi-dimensional dataset pertaining to medical diagnosis and treatment is becoming accessible for mathematical modelling. However, these datasets are frequently inconsistent, noisy, and often characterized by a significant degree of redundancy. Thus, extensive data processing is widely advised to clean the dataset before feeding it into the mathematical model.

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Background: Coinfection with bacteria, fungi, and respiratory viruses has been described as a factor associated with more severe clinical outcomes in children with COVID-19. Such coinfections in children with COVID-19 have been reported to increase morbidity and mortality. Objectives: To identify the type and proportion of coinfections with SARS-CoV-2 and bacteria, fungi, and/or respiratory viruses, and investigate the severity of COVID-19 in children.

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An Overview on Phenotypic and Genotypic Characterisation of Carbapenem-Resistant .

Medicina (Kaunas)

November 2022

Department of Medical Microbiology and Parasitology, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian 16150, Malaysia.

Article Synopsis
  • Improper use of antimicrobials has led to a rise in antimicrobial resistance (AMR), particularly the concerning trend of Carbapenem-resistant Enterobacteriaceae (CRE), posing treatment challenges for infected individuals.
  • Bacterial plasmids facilitate the spread of resistance genes among bacteria, and the incidence of CRE continues to rise despite efforts to combat it, necessitating improved identification methods that often require integrated approaches.
  • The review discusses the mechanisms behind Carbapenem resistance, the epidemiology and treatment options for CRE, and emphasizes the need for antibiotic stewardship programs to manage antibiotic use and curb the spread of resistance globally.
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Article Synopsis
  • Intussusception (ISN) in children after COVID-19 infection is uncommon, but evidence suggests a potential link where SARS-CoV-2 might cause immune issues that lead to ISN.
  • A systematic review was conducted to assess the prevalence of SARS-CoV-2 in ISN cases among pediatric patients, focusing on demographics, clinical characteristics, and treatment outcomes from studies published between December 2019 and October 2022.
  • The review included 34 studies analyzing 64 ISN patients with confirmed COVID-19, showing a low rate of COVID-19 infection in ISN cases and varying success rates for treatment methods, with most affected children being under 12 months old and predominantly male.
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Reverse zoonosis and its relevance to the monkeypox outbreak 2022.

New Microbes New Infect

November 2022

Department of Veterinary Anatomy and Histology, College of Veterinary Sciences and Animal Husbandry, Central Agricultural University (I), Selesih, Aizawl, 796015, Mizoram, India.

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Efficacy and Safety of Vasopressin and Terlipressin in Preterm Neonates: A Systematic Review.

Int J Environ Res Public Health

October 2022

Division of Neonatology, Department of Pediatrics, McMaster University, Hamilton, ON L8S 4L8, Canada.

Introduction: The use of arginine vasopressin (AVP) and terlipressin to treat hypotension in preterm neonates is increasing. Our aim was to review the available evidence on the efficacy and safety of AVP and terlipressin for use in preterm neonates.

Methods: MEDLINE, EMBASE, the Cochrane Central Register of Controlled Trials, Web of Science, and Google Scholar from inception to September 2021 were searched for studies of AVP and terlipressin in the treatment of hypotension of any cause in preterm neonates.

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Monkeypox lineages amid the ongoing COVID-19 pandemic: A global public health concern - Correspondence.

Int J Surg

November 2022

Department of Chemistry, Government College of Engineering, Keonjhar, 758002, Odisha, India Department of Microbiology, Prathima Institute of Medical Sciences, Karimnagar, 505417, Telangana, India Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, G4 0RE, UK Department of Chemistry, School of Applied Sciences, Centurion University of Technology and Management, Odisha, India School of Biotechnology, Campus-11, KIIT Deemed-to-be-University, Bhubaneswar, Odisha, 751024, India Molecular Diagnostic Laboratory, Johns Hopkins Aramco Healthcare, Dhahran, 31311, Saudi Arabia College of Medicine, Alfaisal University, Riyadh, 11533, Saudi Arabia Department of Public Health and Nutrition, The University of Haripur, Haripur, 22610, Pakistan Administration of Pharmaceutical Care, Al-Ahsa Health Cluster, Ministry of Health, Al-Ahsa, 31982, Saudi Arabia Research Center, Almoosa Specialist Hospital, Al-Ahsa, 36342, Saudi Arabia College of Nursing, Princess Norah Bint Abdulrahman University, Riyadh, 11564, Saudi Arabia School of Nursing, Wollongong University, Wollongong, NSW, 2522, Australia Nursing Department, Prince Sultan Military College of Health Sciences, Dhahran, 33048, Saudi Arabia Division of Pathology, ICAR-Indian Veterinary Research Institute, Bareilly, Uttar Pradesh, 243122, India.

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A Comprehensive Review on the Current Vaccines and Their Efficacies to Combat SARS-CoV-2 Variants.

Vaccines (Basel)

October 2022

Administration of Pharmaceutical Care, Al-Ahsa Health Cluster, Ministry of Health, Al-Ahsa 31982, Saudi Arabia.

Since the first case of Coronavirus disease (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in 2019, SARS-CoV-2 infection has affected many individuals worldwide. Eventually, some highly infectious mutants-caused by frequent genetic recombination-have been reported for SARS-CoV-2 that can potentially escape from the immune responses and induce long-term immunity, linked with a high mortality rate. In addition, several reports stated that vaccines designed for the SARS-CoV-2 wild-type variant have mixed responses against the variants of concern (VOCs) and variants of interest (VOIs) in the human population.

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Background: Among gram-negative bacteria, Klebsiella pneumoniae is one of the most common causes of healthcare-related infection. Bloodstream infections (BSIs) caused by Klebsiella pneumoniae are notorious for being difficult to treat due to resistance to commonly used antimicrobials. Klebsiella pneumoniae isolates from bloodstream infections are becoming increasingly resistant to carbapenems.

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Tools to Alleviate the Drug Resistance in .

Molecules

October 2022

Administration of Pharmaceutical Care, Al-Ahsa Health Cluster, Ministry of Health, Al-Ahsa 31982, Saudi Arabia.

Mycobacterium tuberculosis (), an acid-fast bacillus that causes Tuberculosis (TB), is a pathogen that caused 1.5 million deaths in 2020. As per WHO estimates, another 4.

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Background The skin is the largest organ of the body. Burns are important health issues that significantly affect a variety of population groups. Skin grafting is still regarded as the gold standard in surgical burn treatment.

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Context: Studies from high-income countries indicates that infants born preterm are at increased risk of respiratory infections; however in the low and middle-income countries (LMICs) data are limited. Our aim was to systematically review the studies evaluating the risk of respiratory infections in preterm children born in LMICs.

Methods: We searched Medline, PubMed, Cumulative Index of Nursing and Allied Health Literature, Embase, and Psych-INFO databases for studies reporting respiratory outcomes in children born preterm in LMICs.

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Countries worldwide have deployed mass COVID-19 vaccination drives, but there are people who are hesitant to receive the vaccine. Studies assessing the factors associated with COVID-19 vaccination hesitancy are inconclusive. This study aimed to assess the global prevalence of COVID-19 vaccination hesitancy and determine the potential factors associated with such hesitancy.

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