2 results match your criteria: "Prince of Wales HospitalSydney[Affiliation]"
Corrigendum: Identification of Cerebral Metal Ion Imbalance in the Brain of Ageing .
Front Aging Neurosci
May 2017
Centre for Healthy Brain Ageing, School of Psychiatry, Faculty of Medicine, University of New South WalesSydney, NSW, Australia.
[This corrects the article on p. 66 in vol. 9, PMID: 28405187.
View Article and Find Full Text PDFIdentification of Cerebral Metal Ion Imbalance in the Brain of Aging .
Front Aging Neurosci
March 2017
Centre for Healthy Brain Ageing, School of Psychiatry, Faculty of Medicine, University of New South WalesSydney, NSW, Australia; Neuropsychiatric Institute, Euroa Centre, Prince of Wales HospitalSydney, NSW, Australia.
The accumulation of redox-active transition metals in the brain and metal dyshomeostasis are thought to be associated with the etiology and pathogenesis of several neurodegenerative diseases, and Alzheimer's disease (AD) in particular. As well, distinct biometal imaging and role of metal uptake transporters are central to understanding AD pathogenesis and aging but remain elusive, due inappropriate detection methods. We therefore hypothesized that develop neuropathological abnormalities in the distribution of redox active biometals, and this effect may be due to alterations in the expression of lysosomal protein, major Fe/Cu transporters, and selected Zn transporters (ZnTs and ZIPs).
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