Dressing membrane composites of PVA/chitosan/MgO nanoparticles for wound healing applications in rat model.

Chitosan (CS) has excellent film-forming properties; unfortunately, its use as a film wound dressing is limited because of its weak mechanical properties, especially in its wet state. For this reason, modifications with different materials are investigated in this study. The aim of this work was the combination of chitosan with poly (vinyl alcohol) (PVA), magnesium oxide nanoparticles (MgO), and glycerol as a plasticizer agent which can strengthen CS films, increase their flexibility, and enhance their resistance to microbes.

Examining patient safety protocols amidst the rise of digital health and telemedicine: nurses' perspectives.

Background: Integrating digital health and telemedicine technologies is transforming healthcare delivery. In light of this transition, it is critical to ascertain the efficacy of patient safety protocols and evaluate the awareness of healthcare professionals, particularly nurses, regarding the integration of digital health technologies.

Aim: This study examines the factors influencing the successful adoption of digital health and telemedicine technologies from the nurses' perspective, focusing on ensuring patient safety and enhancing organizational readiness for digital health integration.

Random survival forest model for early prediction of Alzheimer's disease conversion in early and late Mild cognitive impairment stages.

With a clinical trial failure rate of 99.6% for Alzheimer's Disease (AD), early diagnosis is critical. Machine learning (ML) models have shown promising results in early AD prediction, with survival ML models outperforming typical classifiers by providing probabilities of disease progression over time.

Understanding decision making for the use of atraumatic restorative approach based on non-clinical factors by Indian pedodontists - a conjoint analysis.

Background: Atraumatic Restorative Treatment (ART) approach is considered as one of the minimally invasive interventions. The success of restoration depends on various clinical factors like material, patient and operator factor. Conjoint analysis is a technique for measuring individual's preference structures via systematical variations of products attributes in an experimental design.

Sublingual Fast-Dissolving Thin Films of Loratadine: Characterization, In Vitro and Ex Vivo Evaluation.

Loratadine (LOR) is a second-generation antihistamine that exhibits a low and variable oral bioavailability (10-40%) and delayed onset owing to poor solubility and an extensive first-pass effect. Therefore, in light of the clinical need, the main goal of the present study was to develop sublingual fast-dissolving thin films of LOR-citric acid co-amorphous systems (LOR-CAs) with the aim of eliciting a faster onset and improving the bioavailability. We formulated sublingual fast-dissolving thin films of LOR by a film-casting technique using hydrophilic polymers like hydroxypropyl methylcellulose (HPMC E15), polyvinyl pyrrolidone K30 (PVP K30), and hydroxypropyl cellulose EL (HPC-EF) and citric acid as a pH modulator, while glycerin served as a plasticizer.

2D-based electrode materials for supercapacitors - status, challenges, and prospects.

The pursuit of efficient and sustainable energy storage solutions has fueled significant interest in the development of advanced materials for supercapacitors. Among these, two-dimensional (2D) materials undoubtingly have emerged as promising candidates due to their unique structural and electrochemical properties. To address the inherent challenges such as restacking, limited ion-accessibility, limited scalability, stability under operational conditions, and the intricate balance between surface area and conductivity that hinder the practical application of 2D materials, this article delves into innovative approaches and emerging strategies and prospects that aim to enhance their performance and durability.

Self-Etching Ceramic Primer Affects Surface Topography and Roughness of Two Zirconia-Reinforced Lithium Silicate Ceramics.

Objective:  This article evaluates the etching efficacy of a self-etching ceramic primer (SECP) on zirconia-reinforced lithium silicate (ZLS) ceramics.

Materials And Methods:  Celtra Duo (DeguDent GmbH, Hanau-Wolfgang, Germany) and Vita Suprinity (Vita Zahnfabrik, Bad Säckingen, Germany) were used in this study. A total of 36 ceramic slices were prepared from each ceramic material and randomly distributed into three groups according to the surface treatment applied ( = 12 per group).

Exploring the reclamation pathway science of Beachwood powder for pharmaceutical acetaminophen drug effluent management.

High effective low-cost substance derived from agriculture-based waste towards a circular economy concept showed a significant green approach for pharmaceuticals uptake in aqueous solution. Beachwood sawdust was used as the source of cellulose based adsorbents. Cellulose is isolated from the waste and in parallel magnetite nanoparticles are prepared by the simple co-precipitation technique and the two substances are mixed in various proportions to be acetaminophen adsorbent.

Artificial Intelligence and its Awareness and Utilization among Dental Students and Private Dental Practitioners at Alkharj, Saudi Arabia.

Introduction: Artificial intelligence (AI) is commonly used in the modern day medical system for medical and dental imaging diagnostics, decision support, precision, hospital monitoring, robotic assistants, and so on. All branches of dentistry have a role of AI, like endodontics, cancer diagnosis, and cephalometric analysis. With the advancing technology, dental professionals need to upgrade themselves.

Assessment of Factors Affecting the Success of Endodontic Retreatment Procedures.

Background: Endodontic retreatment is crucial for preserving dental health but is influenced by various factors.

Objective: This research aimed to assess factors affecting the success of endodontic retreatment procedures.

Methods: A retrospective analysis was conducted on 250 cases of endodontic retreatment.

Exploring the use of Virtual Surgical Planning (VSP) in Maxillofacial Reconstructions.

Background: Virtual surgical planning (VSG), also known as computer-assisted reconstruction, has started to become the norm for more complex patients in many centers in recent times.

Aim: This study was conducted to evaluate the VSG in maxillofacial reconstruction surgery.

Methods And Materials: This study included 20 patients who underwent surgery for maxillofacial reconstruction.

CBCT: A Comprehensive Overview of its Applications and Clinical Significance in Dentistry.

This review provides a comprehensive overview of cone beam computed tomography (CBCT) in dentistry. It covers the basic principles, various applications, advantages, limitations, considerations, and future prospects of CBCT in the field of dentistry.

Efficacy of Structured Teaching Programs in Improving Oral Hygiene Knowledge among School Children at Alkharj, Saudi Arabia.

Introduction: Children's knowledge of oral hygiene is very important to have a good oral health. Health education intervention is the best way to impart oral hygiene knowledge to children, which is cost-effective also.

Aim Of The Study: To evaluate the effectiveness of a structured teaching program in improving the existing oral hygiene knowledge of children in the age group of 10-12 years.

The Evolution of Digital Dentistry: A Comprehensive Review.

Digital dentistry has revolutionized the traditional practice of dentistry, offering new tools and technologies that enhance diagnosis, treatment, and patient care. This comprehensive review explores the evolution of digital dentistry, its role in modern dental practice, and the advantages, limitations, and future prospects. By examining the current state of digital dentistry, this review aims to provide insights into its transformative impact on dental healthcare.

Assessing the Impact of Dental Implant Length on Early Failure Rates: A Retrospective Analysis.

Introduction: The selection criteria of implant is very critical. Implant length determines the mechanics of osseointegration.

Objective: To investigate the influence of dental implant length on early failure rates, osseointegration success, peri-implant bone loss, and patient-reported outcomes.

Biomedical Waste Management Knowledge among Dental Students and Private Dental Practitioners of Alkharj, Saudi Arabia.

Introduction: Improper handling of biomedical waste causes health hazards. Dental practitioners and students as health care professionals should know about biomedical waste management from its generation to disposal. This will prevent associated risk and cross-infection.

pH-Sensitive Tacrolimus loaded nanostructured lipid carriers for the treatment of inflammatory bowel disease.

Inflammatory Bowel Disease is the chronic tissue inflammation of the lower part of the Gastrointestinal tract (GIT). Conventional therapeutic approaches face numerous challenges, often making the delivery system inadequate for treating the disease. This study aimed to integrate a pH-sensitive polymer and nanostructured lipid carriers (NLCs) to develop a hybrid nanocarrier system.

The Interplay of Carveol and All-Trans Retinoic Acid (ATRA) in Experimental Parkinson's Disease: Role of Inflammasome-Mediated Pyroptosis and Nrf2.

Parkinson's disease (PD) is a debilitating and the second most common neurodegenerative disorder with a high prevalence. PD has a multifaceted etiology characterized by an altered redox state and an excessive inflammatory response. Extensive research has consistently demonstrated the role of the nuclear factor E2-related factor (Nrf2) and inflammasomes, notably NLRP3 in neurodegenerative diseases.

Pharmacological evaluation and binding behavior of 4,4'-diamino-2,2'-stilbene disulfonic acid with metal ions using spectroscopic techniques.

Industrial and human activities contribute significantly to the environmental contamination of heavy metal ions (HMIs), which have detrimental effects on aquatic life, plants, and animals, causing major toxicological problems. The commercially available has been playing a vital role in the detection of heavy metal ions and has significantly inhibited a variety of cancer cells in numerous field of modern science. The current investigation aimed to ensure the detection of heavy metals ions from the environment and fluorescence imaging of DSD in the treatment of cancer cells.