5,909 results match your criteria: "Primitive Neuroectodermal Tumors of the Central Nervous System"
Cancer Med
December 2024
Department of Integrated Oncology, Center for Integrated Oncology (CIO), University Hospital of Bonn, Bonn, Germany.
Background: Cytokine-induced killer (CIK) cell therapy has proven successful in clinical trials regarding glioblastoma. Equally important are the hints suggesting peroxisome proliferator-activated receptors (PPARs) ligands being co-expressed in the central nervous system (CNS). This provides a rationale about investigating the possible synergistic effect of CIK cells and PPARs.
View Article and Find Full Text PDFJ Ayub Med Coll Abbottabad
November 2024
Akbar Niazi Teaching Hospital, IMDC, Islamabad.
Viruses
November 2024
Human Genome and Stem Cell Research Center (CEGH-CEL), Department of Genetics and Evolutionary Biology, Institute of Biosciences, University of São Paulo, Cidade Universitária, São Paulo 05508-090, SP, Brazil.
Metab Brain Dis
November 2024
Department of Zoology, School of Basic Sciences, Central University of Punjab, VPO - Ghudda, Bathinda, 151 401, Punjab, India.
The central nervous system (CNS) involves a complex interplay of communications between the neurons and various glial cells, which is crucial for brain functions. The major interactomes are exosomes that transmit sundry molecules (DNA, miRNAs, and proteins) between the cells and thus alter cell physiology. Exosomes can act as neuroprotective or neurodegenerative agents depending on the microenvironment of cells secreting them.
View Article and Find Full Text PDFCNS Neurosci Ther
November 2024
Department of Neurosurgery, Huashan Hospital, MOE Frontiers Center for Brain Science, Fudan University, Shanghai, China.
J Cancer Res Clin Oncol
October 2024
Department of Radiation Oncology, The Affiliated Cancer Hospital of Zhengzhou University & Henan Cancer Hospital, Zhengzhou, 450008, China.
Clin Nucl Med
January 2025
Department of Nuclear Medicine, Beijing Friendship Hospital of Capital Medical University, Beijing, China.
Cancer Radiother
October 2024
Radiobiology Laboratory, institut de cancérologie Strasbourg Europe (ICANS), 3, rue de la Porte-de-l'Hôpital, 67000 Strasbourg, France; Laboratory of Engineering, Informatics and Imaging (ICube), Integrative multimodal imaging in healthcare (Imis), UMR 7357, université de Strasbourg, 4, rue Kirschleger, 67000 Strasbourg, France. Electronic address:
Radiotherapy (RT) is an integral part of managing pediatric brain tumors, yet many patients develop tumor radioresistance, leading to recurrence and poor clinical outcomes. In addition, neurocognitive impairment is a common long-term side effect of RT, significantly impairing quality of life. Indeed, increasing evidence suggests that the developing child's brain is particularly vulnerable to the neurotoxic effects of ionizing radiation.
View Article and Find Full Text PDFZebrafish
December 2024
Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.
Xenotransplantation of neuroblastoma cells into larval zebrafish allows the characterization of their tumorigenic abilities and high-throughput treatment screening. This established preclinical model traditionally relies on microinjection into the yolk or perivitelline space, leaving the engraftment ability of cells at the hindbrain ventricle (HBV) and pericardial space (PCS), sites valuable for evaluating metastasis, angiogenesis, and the brain microenvironment, unknown. To address this gap in knowledge, Casper zebrafish at 48 h postfertilization were microinjected with approximately 200 Kelly, Be(2)-C, SK-N-AS, or SY5Y cells into either the HBV or PCS.
View Article and Find Full Text PDFPediatr Neurol
December 2024
Department of Pediatrics, Baylor College of Medicine/Texas Children's Hospital, Houston, Texas.
Adv Tech Stand Neurosurg
September 2024
Department of Pediatric Surgery, McGovern Medical School and Children's Memorial Hermann Hospital, Houston, TX, USA.
Brain Res
December 2024
Department of Biochemistry, Faculty of Pharmacy, Sivas Cumhuriyet University, 58140 Sivas, Turkey. Electronic address:
Recent investigations indicate that tannic acid is associated with a decrease in oxidative damage. Growing evidence supports the protective effects of tannic acid on the central nervous system (CNS). However, uncertainties persist regarding its influence on hydrogen peroxide (HO)-triggered oxidative impairment in nerve cells and its interaction with apoptosis.
View Article and Find Full Text PDFPract Radiat Oncol
November 2024
Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
J Diabetes Complications
September 2024
Department of applied science, school of pharmacy, University of Brighton, BN24GJ, UK. Electronic address:
Head Neck
January 2025
Department of Radiation Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, USA.
Background: Treatment for dural recurrence of olfactory neuroblastoma (ONB) is not standardized. We assess the outcomes of stereotactic body radiotherapy (SBRT) in this population.
Methods: ONB patients with dural recurrences treated between 2013 and 2022 on a prospective registry were included.
J Postgrad Med
July 2024
Department of Neurosurgery, Dr Ram Manohar Lohia Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.
Cancer Cell
July 2024
Division of Haematology/Oncology, Developmental and Stem Cell Biology Program, Hospital for Sick Children, Toronto, ON, Canada; Departments of Medical Biophysics and Paediatrics, University of Toronto, Toronto, ON, Canada. Electronic address:
Cell
August 2024
The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, ON, Canada; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON, Canada; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada; Texas Children's Cancer and Hematology Center, Houston, TX, USA; Department of Pediatrics - Hematology/Oncology, Baylor College of Medicine, Houston, TX, USA; Department of Neurosurgery, Baylor College of Medicine, Houston, TX, USA; Department of Neurosurgery, Texas Children's Hospital, Houston, TX, USA; Dan L Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX, USA; Department of Surgery, University of Toronto, Toronto, ON, Canada. Electronic address:
Sci Rep
June 2024
Department of Neurosurgery, The First Affiliated Hospital of Shandong First Medical University, Jinan, 250014, Shandong, China.
Medulloblastoma is a malignant neuroepithelial tumor of the central nervous system. Accurate prediction of prognosis is essential for therapeutic decisions in medulloblastoma patients. We analyzed data from 2,322 medulloblastoma patients using the SEER database and randomly divided the dataset into training and testing datasets in a 7:3 ratio.
View Article and Find Full Text PDFAJNR Am J Neuroradiol
November 2024
From the Department of Radiology (O.S., N.S., A.M., M.W., T.P.R., A.B.), Children's Hospital of Philadelphia, Philadelphia, Pennsylvania
Background And Purpose: Hemangioblastoma is a rare vascular tumor that occurs within the central nervous system in children. Differentiating hemangioblastoma from other posterior fossa tumors can be challenging on imaging, and preoperative diagnosis can change the neurosurgical approach. We hypothesize that a "lightbulb sign" on the arterial spin-labeling (ASL) sequence (diffuse homogeneous intense hyperperfusion within the solid component of the tumor) will provide additional imaging finding to differentiate hemangioblastoma from other posterior fossa tumors.
View Article and Find Full Text PDFEur J Radiol
August 2024
UCL Great Ormond Street Institute of Child Health, 30 Guildford Street, London WC1N 1EH, UK; Great Ormond Street Hospital for Children, Great Ormond St, London WC1N 3JH, UK.
J Imaging Inform Med
December 2024
Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA.
Cell Death Differ
October 2024
Taiwan International Graduate Program in Molecular Medicine, National Yang Ming Chiao Tung University and Academia Sinica, Taipei, Taiwan.
J Neuropathol Exp Neurol
September 2024
Department of Neurosurgery, Kitasato University School of Medicine, Sagamihara, Japan.
J Cell Mol Med
May 2024
Department of Clinical Laboratory Center, Central Hospital of Enshi Tujia and Miao Autonomous Prefecture, Enshi, China.