Statin use is not associated with presence of and severity of nonalcoholic fatty liver disease.

Background And Aims: There is concern that statin use may exacerbate nonalcoholic fatty liver disease (NAFLD). We aimed to assess the association of statin use with NALFD and severity of liver fibrosis among NAFLD individuals.

Methods: We evaluated 6,385 cross-sectional healthy Brazilian subjects (43 ± 10 years, 79% males) without clinical coronary heart disease between November 2008 and July 2010.

GDNF increases cell motility in human colon cancer through VEGF-VEGFR1 interaction.

Glial cell line-derived neurotrophic factor (GDNF), a potent neurotrophic factor, has been shown to affect cancer cell metastasis and invasion. However, the molecular mechanisms underlying GDNF-induced colon cancer cell migration remain unclear. GDNF is found to be positively correlated with malignancy in human colon cancer patients.

The Finnish Diabetes Risk Score (FINDRISC) as a screening tool for hepatic steatosis.

INTRODUCTION. Hepatic steatosis due to non-alcoholic fatty liver disease is associated with obesity, dyslipidemia, insulin resistance, and type 2 diabetes. The Finnish Diabetes Risk Score (FINDRISC) is a prognostic screening tool to detect people at risk for type 2 diabetes without the use of any blood test.

Association of C-reactive protein and homocysteine with subclinical coronary plaque subtype and stenosis using low-dose MDCT coronary angiography.

Objectives: Given the uncertainty regarding the relationship of C-reactive protein (CRP) and homocysteine (Hcy) to atherosclerotic burden, our aim was to determine whether CRP and Hcy are related to the presence of subclinical coronary plaque and stenosis.

Methods: We did a cross-sectional analysis of data gathered on 1248 consecutive, newly self-referred, middle-aged subjects who underwent health check ups at China Medical University Hospital. Participants had at least one cardiac risk factor, but no known coronary heart disease.

Factors associated with inconsistent condom use among female sex workers in Nha Trang, Vietnam.

This study examined consistent condom use with clients, self-reported sexually transmitted infections (STIs), and associated factors among Vietnamese female sex workers (FSWs). Data were collected through a cross-sectional survey among 192 FSWs in Nha Trang city, in 2005. The rate of consistent condom use with casual clients, regular clients, and nonpaying partners were 59.

Stratification of risk in children with familial hypercholesterolemia with focus on psychosocial issues.

Aim: This paper discusses the clinical implications of making a diagnosis of familial hypercholesterolemia (FH) in children and data on psychosocial issues.

Data Summary: The case for treating FH in children is based on pathophysiological considerations. Some authors claim that treatment may be harmful, partly because the psychosocial risks have not been assessed.

Risk factors and early extracoronary atherosclerotic plaques detected by three-site ultrasound imaging in hypercholesterolemic men. Prévention Cardio-vasculaire en Médecine du Travail METRA Group.

Ultrasonic detection of atherosclerotic plaque of carotid abdominal aortic and femoral arteries and evaluation of risk factors were performed in 208 hypercholesterolemic men without cardiovascular disease. Twenty-six percent of them had no plaque. Plaque at the carotid, aortic, and femoral sites was found in 37%, 48%, and 53% of subjects, respectively.

Nicolai S. Korotkoff (1874-1920).

As a 31-year-old surgeon, with special interest in vascular disease, Korotkoff discovered the sounds of the blood pressure in 1905 while working on his doctoral thesis. After publication of the latter, he wrote nothing further about his remarkable discovery. As is often the case, others picked up on it, however, and the technique of measuring arterial blood pressure changed from one of touch to one of hearing.

Medical evaluation, electrocardiographic analysis, and exercise testing of elite women distance runners.

Sixteen elite women runners and 14 good women runners underwent medical history and physical examinations. Resting ECGs were recorded in all and exercise ECGs in 28 of the 30 (two were injured). Women in both groups combined endurance with supplemental strength and flexibility workouts.