12,564 results match your criteria: "Premature Rupture of Membranes"
Sci Rep
October 2024
Department of Obstetrics and Gynecology, Gynecology, Korea University College of Medicine, Korea University Anam Hospital, 73 Goryeodae-Ro, Seongbuk-Gu, Seoul, 02841, Korea.
Preterm birth (PTB) is one of the most common and serious complications of pregnancy, leading to mortality and severe morbidities that can impact lifelong health. PTB could be associated with various maternal medical condition and dental status including periodontitis. The purpose of this study was to identify major predictors of PTB among clinical and dental variables using machine learning methods.
View Article and Find Full Text PDFClin Rheumatol
October 2024
Clinical Research Development Center of Shahid Mohammadi Hospital, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease primarily impacting women of childbearing age. While pregnancy and hormonal stress can trigger SLE flare-ups, the effects of assisted reproductive therapies (ARTs) on SLE patients are not well defined. We conducted a search of PubMed/Medline, Embase, and CENTRAL until March 20, 2024, to find observational studies assessing the prevalence of SLE flares and pregnancy outcomes following ARTs.
View Article and Find Full Text PDFMedicine (Baltimore)
October 2024
Department of Ultrasound, The Second People's Hospital of Yibin, Sichuan Province, Yibin, China.
Rationale: The normal structure and Doppler parameters of the umbilical cord are closely related to many diseases, including fetal infection, chromosomal abnormalities, hypoxia, and growth and development restrictions. We report a case of bilateral umbilical artery confluence resulting in the formation of a single umbilical artery in the free segment of the fetal umbilical cord, diagnosed at 24 weeks and 4 days gestation. The fetus was born prematurely after premature membrane rupture at 31 weeks and 3 days gestation.
View Article and Find Full Text PDFArch Gynecol Obstet
October 2024
Department of Obstetrics and Gynecology, West China Second University Hospital, Sichuan University, No.20, 3rd Section, South Renmin Road, Chengdu, 610041, Sichuan, China.
Eur J Obstet Gynecol Reprod Biol
December 2024
Department of Maternal and Child Health and Urological Sciences, Sapienza University of Rome, Italy. Electronic address:
Sci Rep
October 2024
Department of Pediatrics, Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul, Korea.
Several perinatal factors influence the intestinal microbiome of newborns during the first days of life, whether during delivery or even in utero. These factors may increase the risk of developing necrotizing enterocolitis (NEC) by causing dysbiosis linked to a NEC-associated microbiota, which may also be associated with other gastrointestinal problems. The objective of our study was to evaluate the potential risks associated with microbial shifts in newborns with gastrointestinal symptoms and identify the intestinal microbiota of neonates at risk for NEC.
View Article and Find Full Text PDFJ Neonatal Perinatal Med
October 2024
Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Background: Our objectives were to determine 1) the prevalence and description of placental pathologic lesions in pregnancies complicated by SARS-CoV-2 infection compared to healthy controls and 2) whether the prevalence and/ or pattern of placental pathologic lesions differed in the few neonates who tested positive for SARS-CoV-2 in the first 48 hours of life at a busy urban county hospital.
Methods: This study included all pregnant mothers who tested positive for SARS-CoV-2 and delivered at our institution from March 2020 to June 2021, while control placentas were collected from term pregnancies without complications.
Results: Approximately 90% (n = 380/425) of placentas from pregnancies complicated by SARS-CoV-2 infections had placental pathologic lesions, compared to 32% (n = 16/50) of controls.
Matern Child Health J
December 2024
INFANT Research Centre, University College Cork, Cork, Ireland.
Objectives: Development and validation of risk prediction models at mid-pregnancy and delivery to predict admission to the neonatal care unit.
Methods: We used data from all singleton deliveries at Cork University Maternity Hospital (CUMH), Ireland during 2019. Admission to the neonatal care unit was assumed if length of stay in the unit was > 24 h.
Pak J Med Sci
October 2024
Xinyue Li, Department of Paediatrics, Maternity & Child Care Center of Qinhuangdao, Qinhuangdao 066000, Hebei, China.
Am J Reprod Immunol
October 2024
Department of Pathology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
Problem: The placental membranes are a key barrier to fetal and uterine infection. Inflammation of the membranes, diagnosed as maternal inflammatory response (MIR) or alternatively as acute chorioamnionitis, is associated with adverse maternal-fetal outcomes. MIR is staged 1-3, with higher stages indicating more hazardous inflammation.
View Article and Find Full Text PDFNutrients
October 2024
Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing 100191, China.
The relationship between the intake of artificial sweetener (AS) and adverse pregnancy outcomes is under-researched, and existing studies yield inconsistent conclusions. A Mendelian randomization (MR) approach was employed to investigate the causal relationship between the intake of AS and adverse pregnancy outcomes. Instrumental variables related to the exposure phenotype were selected for analysis.
View Article and Find Full Text PDFJ Clin Med
September 2024
Maternal Fetal Care Center, Division of Fetal Medicine and Surgery, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Obesity rates have significantly increased globally, affecting up to 40% of women of childbearing age in the United States. While prenatal repair of open fetal spina bifida has shown improved outcomes, most fetal surgery centers exclude patients with a body mass index (BMI) ≥ 35 kg/m based on criteria from the Management of Myelomeningocele Study (MOMS) trial. This exclusion raises concerns about healthcare equity and highlights a significant knowledge gap regarding the safety and efficacy of fetal spina bifida repair in patients with obesity.
View Article and Find Full Text PDFAm J Perinatol
October 2024
Department of Pediatrics, Uniformed Services University of the Health Sciences, Bethesda, Maryland.
Objective: To clarify survival for infants affected by periviable prolonged preterm premature rupture of membranes (PPROM) in the military health system (MHS). To add to current literature on outcomes following expectant management, including long-term neurodevelopment outcomes.
Study Design: Retrospective matched cohort review of six level 3 military neonatal intensive care units (NICUs; 2010-2020).
J Perinat Med
November 2024
Department of Obstetrics and Gynecology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Objectives: , or Group B (GBS), is a leading cause of neonatal sepsis. Materno-fetal transmission of the microorganisms present in the lower genital tract/perineum is considered to be the most frequent mode for acquisition of infection. It has also been proposed that, in a subset of cases, GBS causes acute chorioamnionitis, intraamniotic infection, and fetal/neonatal sepsis.
View Article and Find Full Text PDFAm Surg
October 2024
University of California, Irvine, Department of Surgery, Division of Trauma, Burns and Surgical Critical Care, Orange, California, USA.
Cureus
September 2024
Department of Obstetrics and Gynaecology, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, IND.
Indian J Med Microbiol
December 2024
Department of Obstetrics and Gynecology, Chengdu Women's and Children's Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu 611731, China. Electronic address:
Am J Obstet Gynecol MFM
November 2024
Department of Obstetrics and Gynecology and Reproductive Sciences, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX.
JNMA J Nepal Med Assoc
July 2024
Department of Obstetrics and Gynaecology, Kathmandu Medical College and Teaching Hospital, Sinamangal, Kathmandu, Nepal.
Introduction: Premature rupture of membrane (PROM) refers to the disruption of the fetal membrane before the beginning of labor, resulting in spontaneous leakage of amniotic fluid. Cervicovaginal infection is an important risk factor of PROM and can lead to complications to mother and the child. This study aimed to delineate the bacterial patterns found in PROM so that the ideal appropriate responsive antibiotics can be chosen.
View Article and Find Full Text PDFBMC Pregnancy Childbirth
October 2024
Departamento de Inmunobioquímica, Instituto Nacional de Perinatología Isidro Espinosa de los Reyes, Urales #800 Col. Lomas de Virreyes CP 11000, Tercer piso de la Torre de Investigación, Ciudad de México, México.
Background: Escherichia coli (E. coli) is one of the main bacteria associated with preterm premature rupture of membranes by increasing pro-matrix metalloproteinase 9 (proMMP-9) and degradation of type IV collagen in human feto-maternal interface (HFMi). proMMP-9 is regulated by progesterone (P4) but it is unclear whether P4 inhibits proMMP in human maternal decidual (MDec).
View Article and Find Full Text PDFReprod Sci
October 2024
Department of Obstetrics, Longgang Maternity and Child Institute of Shantou University Medical College, Shenzhen, 518172, China.
Premature rupture of membranes (PROM), with a prevalence of 15.3% in China, frequently results in adverse pregnancy outcomes. In this study, we aimed to identify amino acid metabolites that were differentially expressed in PROM versus healthy controls (HC) using targeted metabolomics and further explored their mechanisms of action with in vitro models.
View Article and Find Full Text PDFPol Merkur Lekarski
October 2024
Shupyk National Healthcare University of Ukraine, Kyiv, Ukraine.
Front Pediatr
September 2024
Neonatal Medical Centre, Maternity and Child Health Hospital of Guangxi Zhuang Autonomous Region, Nanning, China.
Objective: This study aimed to develop and validate a model for predicting extrauterine growth restriction (EUGR) in preterm infants born ≤34 weeks gestation.
Methods: Preterm infants from Guangxi Maternal and Child Health Hospital (2019-2021) were randomly divided into training (80%) and testing (20%) sets. Collinear clinical variables were excluded using Pearson correlation coefficients.
Geburtshilfe Frauenheilkd
October 2024
Klinik für Frauenheilkunde und Geburtshilfe, Universitätsklinikum Ulm, Ulm, Germany.
Purpose: The aim of the study was to describe the preventive option and safety of laparoscopic transabdominal emergency cerclage in pregnant women with advanced cervical shortening after failed vaginal cerclage or in whom vaginal cerclage is no longer possible.
Method: Laparoscopic isthmo-cervical emergency cerclage was carried out in two patients at 13+0 and 15+5 weeks of gestation (GW) respectively. Both patients had cervical shortening and it was no longer possible to expose the cervix after conization or re-conization.