12,582 results match your criteria: "Premature Rupture of Membranes"

Background And Objectives: Studies have identified increased risks of pregnancy complications in expectant mothers with atopic dermatitis (AD). However, the associations between maternal AD and adverse pregnancy or offspring outcomes in Asians remain unexplored. Our aim was to investigate the relationship between maternal AD and adverse pregnancy and offspring outcomes in Taiwan.

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Objective: To assess the neonatal survival rates, maternal complications, neonatal complications, and factors associated with survival rates following periviable premature rupture of membranes (PROM) between 15 and 23 weeks of gestation.

Materials And Methods: The retrospective study included patients with periviable PROM between 15 and 23 weeks of gestation from January 1, 2008, to December 31, 2022. Multivariate regression analysis was performed to identify factors influencing neonatal survival.

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Impact of Low Maternal Weight on Pregnancy and Neonatal Outcomes.

J Endocr Soc

November 2024

Department of Medicine, Division of Endocrinology and Metabolism, Neuroendocrinology Unit, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.

Objective: To examine the effect of underweight maternal body mass index (BMI) on pregnancy complications and neonatal outcomes.

Design: Cohort study.

Setting: Tertiary academic center.

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Introduction: Chronic endometritis (CE) is a prolonged, mild inflammation of the endometrial lining. This study investigated the impact of the impact of antibiotic treatment combined with vaginal on pregnancy outcomes in infertile patients with CE during frozen embryo transfer (FET) cycles.

Methods: A retrospective analysis was performed on the clinical data of 7,385 patients who underwent FET.

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Background: Preterm birth is a significant concern in multiple pregnancies, warranting effective strategies to improve outcomes. Delaying delivery of the second fetus is crucial for reducing perinatal mortality rates.

Case Presentation: In a dichorionic diamniotic twin pregnancy, one fetus experienced premature rupture of membranes (PROM) at 16+6 weeks gestation.

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Genetic Causal Association Between 15 Micronutrients and 12 Obstetric-Related Diseases: A Mendelian Randomization Study.

Biol Trace Elem Res

December 2024

Department of Obstetrics and Gynecology, Guangdong Women and Children Hospital, No. 13 Guangyuan West Road, Guangzhou, 510000, Guangdong Province, China.

Article Synopsis
  • Micronutrients like vitamins and minerals significantly influence pregnancy outcomes, but previous research findings have been inconsistent.
  • A genetic analysis was conducted to explore the causal relationship between 15 micronutrient levels and 12 pregnancy-related diseases, revealing specific effects of certain nutrients, such as iron offering protection against gestational diabetes, while zinc and vitamin B6 increased risks for hypertension and spontaneous abortion, respectively.
  • The study highlights the importance of understanding these associations to help healthcare providers offer personalized nutrition advice to women pre- and during pregnancy, enhancing efforts to prevent complications.
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  • The study aimed to examine the demographic, maternal, and perinatal factors linked to hospitalizations of moderately to late preterm and term neonates within 72 hours of birth in Malawi's Dedza and Mangochi districts.
  • Various factors were analyzed using a case-control method, comparing sick neonates admitted to intensive care with healthy ones, with data collected through case files and caregiver interviews.
  • Results indicated that certain practices, like using tetracycline eye ointment and proper umbilical cord care, reduced hospitalization odds, while factors such as low birth weight and poor Apgar scores significantly increased hospitalization risks.
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  • The text indicates that there is a correction related to the article identified by the DOI: 10.1371/journal.pone.0277098.
  • It implies that there may have been errors or updates necessary for clarification in the original publication.
  • This correction is important for maintaining the accuracy and integrity of the research presented in the article.
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Introduction: Twin reversed arterial perfusion (TRAP) sequence is a rare complication of monochorionic twin pregnancies characterized by placental anastomoses between a normally developed twin and an acardiac mass. Though several treatment modalities exist, the optimal management strategy is unclear. This study aims to compare the various treatment strategies for TRAP sequence.

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  • The study investigates the mechanical strength of fetal membranes in women at risk for preterm premature rupture of membranes (PPROM) through a series of tensile tests on tissue samples collected from pregnant women undergoing cesarean sections.
  • Results indicate that first-time mothers (primiparous) have weaker fetal membranes compared to those with previous births, while factors like gestational diabetes and geographic origin affect membrane properties such as thickness and mechanical strength.
  • Overall, thicker membranes show decreased rigidity and resistance, highlighting the complex interplay between various risk factors and membrane integrity in pregnancy.
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Introduction: Intraamniotic infection (IAI) is one of the main possible complications of preterm prelabor rupture of membranes (PPROM) and can lead to severe consequences for the neonate, such as early onset neonatal sepsis (EONS). Available diagnostic tools for IAI have poor diagnostic performance, which may result in both over- and underdiagnoses of IAI. In a search for better diagnostic tools, we have examined short-term variation (STV) in fetal heart rate.

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Article Synopsis
  • * Researchers conducted a retrospective review of 546 GDM patients, comparing those who received the one-day outpatient management to those who only got routine education, focusing on various health metrics and pregnancy outcomes.
  • * Results showed that patients in the experimental group had significantly lower blood glucose levels, less weight gain, improved achievement of weight goals, and fewer pregnancy complications compared to the control group.
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Background: Suspected preterm labour (PTL) and prelabour rupture of membranes (PPROM) are common indications for aeromedical retrieval in the Top End, Northern Territory, Australia, where many women reside remotely and preterm birth (< 37 completed weeks of gestation) is common. The primary objective of this study was to determine rate of delivery during the index admission following aeromedical transfers from remote clinics to Royal Darwin Hospital for suspected PTL/PPROM.

Methods: A retrospective cohort study of aeromedical transfers for suspected PTL/PPROM from 1 January 2020 to 31 July 2022 was undertaken.

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Article Synopsis
  • Premature rupture of membranes (PROM) contributes to higher risks of death and health issues in newborns, making it critical to identify its influencing factors.
  • * A study was conducted at three public hospitals in Northeast Ethiopia involving 353 women in labor to explore the factors associated with PROM between December 2022 and March 2023.
  • * Key determinants identified included a history of cesarean sections, abortions, previous PROM, chronic cough, malnutrition, suspected sepsis, and urinary tract infections, emphasizing the importance of thorough prenatal care.
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Potential causal associations between perfluoroalkyl substances exposure and adverse pregnancy outcomes: A bidirectional two-sample mendelian randomization study.

Ecotoxicol Environ Saf

December 2024

Department of Reproductive Endocrinology, Women's Hospital, School of Medicine, Zhejiang University, Hangzhou, China. Electronic address:

Maternal exposure to per- and polyfluoroalkyl substances (PFASs) has been linked to adverse pregnancy outcomes (APOs). Nonetheless, the genetic causality underlying this association remains unknown. This research employed a bidirectional two-sample Mendelian randomization (MR) to investigate the potential causal associations between PFASs exposure and APOs risk.

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Factors associated with the incidence of low birth weight in Pontianak City, Indonesia.

Med J Malaysia

November 2024

Institut Teknologi dan Kesehatan Muhammadiyah, Kalimantan Barat, Indonesia.

Introduction: The weight of an infant at the time of birth is an indicator of its health. Infants with low birth weight (LBW) are at a higher risk of neonatal mortality and morbidity as well as stunted growth. Low birth weight (LBW) remains a public health concern in developing countries, such as Indonesia.

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Preterm premature rupture of membranes in the late preterm period: an argument against expectant management.

Am J Obstet Gynecol MFM

November 2024

Division of Maternal-Fetal Medicine, Department of Obstetrics, Gynecology, and Reproductive Sciences, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX.

Article Synopsis
  • Preterm premature rupture of membranes (PPROM) occurs when amniotic fluid leaks before 37 weeks of pregnancy, impacting about 3% of deliveries and 30% of late preterm deliveries.
  • Management strategies for PPROM between 34 to 36 weeks have shifted from solely recommending delivery to considering either delivery or monitoring (expectant management), following a significant trial on the topic.
  • Immediate delivery is advised at 34 weeks due to higher risks of complications for mothers, such as hemorrhage and infection, with limited evidence suggesting that immediate delivery doesn't significantly increase adverse outcomes for newborns compared to expectant management.
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Clinical characteristics associated with peripartum maternal bloodstream infection.

Front Microbiol

November 2024

Tianjin Key Laboratory of Female Reproductive Health and Eugenics, Tianjin Medical University General Hospital, Tianjin, China.

Objective: Bloodstream infection (BSI) during the peripartum period is a major cause of maternal morbidity and mortality. However, data on maternal BSI during hospitalization for delivery are limited. This study aimed to investigate the incidence, clinical characteristics, risk factors, microbiological features, and antibiotic resistance patterns of maternal peripartum BSI, with a focus on understanding the role of premature rupture of membranes (PROM), fever, and other risk factors in its development.

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Introduction: The purpose of the review was to examine the impact of maternal body mass index (BMI) on outcomes of cervical cerclage for cervical insufficiency.

Methods: This prospectively registered review (CRD42024512436) searched PubMed, Embase, Scopus, and Web of Science for comparative studies published before 6 March 2024. Maternal and neonatal outcomes of females undergoing cerclage were compared based on BMI.

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Article Synopsis
  • Multidrug-resistant urinary tract infections (MDR UTIs) are a significant public health issue for pregnant women, prompting a study to analyze the types of bacteria involved and their resistance patterns.
  • The study included 371 pregnant patients with UTIs, categorizing them based on their resistance to antibiotics into four groups, and used statistical methods to assess the impact of these infections on pregnancy outcomes.
  • Key findings revealed that MDR UTIs are associated with high resistance to common antibiotics like ampicillin and increased risks of complications such as preterm birth and neonatal health issues, highlighting the need for improved treatment protocols.
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Successful Delayed Interval Delivery in Twin Pregnancy After Early Premature Rupture of Membranes of a Leading Fetus: A Case Report.

Medicina (Kaunas)

November 2024

Department of Obstetrics and Gynecology, Daegu Dongsan Hospital, Keimyung University School of Medicine, 56, Dalseong-ro, Jung-gu, Daegu 41931, Republic of Korea.

A 36-year-old primigravida conceived dichorionic diamniotic twins via in vitro fertilization. The first twin experienced premature rupture of membranes at 18 weeks and 5 days of gestation. Despite antibiotic treatment, the first fetus suffered intrauterine fetal death and was delivered three days later at 19 weeks and 1 day.

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The Immunomodulatory Role of Regulatory T Cells in Preterm Birth and Associated Pregnancy Outcomes.

Int J Mol Sci

November 2024

School of Life Course & Population Sciences, King's College London, 10th Floor North Wing, St Thomas' Hospital, London SE1 7EH, UK.

Spontaneous preterm birth (sPTB), defined as live birth before 37 weeks of gestational age, is associated with immune dysregulation and pro-inflammatory conditions that profoundly impact newborn health. The question of immune integrity at the maternal-foetal interface is a focus of recent studies centring not only sPTB but the conditions often affiliated with this outcome. Regulatory T cells (Tregs) play a critical anti-inflammatory role in pregnancy, promoting foetal tolerance and placentation.

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Objective: This study aimed to explore whether subclinical hypothyroidism (SCH) treated with levothyroxine in pregnancy complicated by gestational diabetes mellitus (GDM) is associated with an increased risk of gestational hypertensive disorders (GHDs) (gestational hypertension and preeclampsia).

Methods: 96 pregnant women with GDM were enrolled in this study and grouped as per the European Thyroid Association criteria into the SCH (n = 21) and euthyroid groups (n = 75). All subjects were tested for anthropometric parameters, maternal glucose homeostasis parameters, lipid levels, thyroid function tests, and blood pressure.

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Article Synopsis
  • PPHN (Persistent Pulmonary Hypertension of the Newborn) is a serious condition leading to neonatal respiratory failure, with high mortality rates, especially when combined with SARS-CoV-2 infection.
  • A systematic review of existing literature identified 21 relevant studies involving 36 neonates with PPHN and COVID-19, revealing that most were male, of Indian ethnicity, and born via caesarean section, with a majority having moderate to late preterm gestations.
  • The findings indicated significant severe cases of COVID-19 in these neonates, with symptoms like ARDS affecting over half, and notable occurrences of multisystem inflammatory syndrome in neonates, highlighting the need for close monitoring and care in this patient population
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