802 results match your criteria: "Pregnancy and Urolithiasis"

Special Considerations in the Treatment of Idiopathic Intracranial Hypertension.

Curr Neurol Neurosci Rep

December 2024

Yellow Rose Headache and Neuro-Ophthalmology, 12740 Hillcrest Road, Suite 269, Dallas, TX, 75230, USA.

Purpose Of Review: To review the management of Idiopathic Intracranial Hypertension (IIH) with co-existing conditions affecting therapy: obesity, sulfa allergy, nephrolithiasis, and pregnancy.

Recent Findings: The IIH-WT trial showed that bariatric surgery is currently the most effective method for obese patients with IIH to lose weight, leading to normalization of CSF pressure in many cases. Allergy to sulfonamide antibiotics does not preclude the use of acetazolamide; rather, penicillin allergy or multiple drug allergies are the strongest predictor of a hypersensitivity reaction.

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Article Synopsis
  • - Renal colic is the most common abdominal pain in pregnancy and can lead to complications, requiring treatments like ureteral stent (JJ), percutaneous nephrostomy (PCN), or ureteroscopy (URS) for urolithiasis management.
  • - A systematic review analyzed 45 studies involving 3424 procedures in pregnant women, finding URS to be the most evaluated with similar success rates to non-pregnant patients, although complications like infections and preterm labor were noted.
  • - Despite a lack of high-quality evidence, URS, JJ, and PCN are deemed safe and effective in pregnancy, with URS being the preferred treatment option due to its efficiency and lower need for follow-up procedures
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Uroabdomen secondary to spontaneous bladder rupture in a dog with dystocia.

J Vet Emerg Crit Care (San Antonio)

October 2024

Department of Small Animal Clinical Sciences, Texas A&M University Veterinary Teaching Hospital, College Station, Texas, USA.

Objective: To describe the development of uroabdomen secondary to spontaneous bladder rupture in a dog with dystocia.

Case Summary: A 2-year-old intact female Boston Terrier was referred for prolonged labor of 72 hours. At presentation, the dog had delivered 8 puppies at home, with the last pup being stillborn.

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Objective: The diagnosis of symptomatic urinary stones during pregnancy is challenging; ultrasonography has a low specificity and sensitivity for diagnosing urinary stones. This study aimed to develop a clinical diagnostic model to assist clinicians in distinguishing symptomatic urinary stones in pregnant women.

Methods: In this retrospective cohort study, we consecutively collected clinical data from pregnant women who presented with acute abdominal, lumbar, and lumbar and abdominal pain at the emergency department of our hospital between January 1, 2017, and December 31, 2019.

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Article Synopsis
  • Kidney stones during pregnancy are rare but difficult to manage, and there's no comprehensive survey on current management practices globally.
  • A 19-item survey was developed to evaluate how different regions handle kidney stones in pregnant patients, covering demographics, diagnosis, and treatment options.
  • Results showed that most hospitals lack a clear protocol, with ultrasound as the preferred imaging method, but the use of CT scans is growing, especially when ultrasound results are unclear.
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Introduction Renal calculi, commonly known as kidney stones, affect approximately 12% of the global population, often resulting in mild to severe pain and complications such as infection and renal failure. The causes are multifactorial, involving lifestyle factors, genetic predisposition, and various medical conditions. Despite advancements in treatment, the incidence of kidney stones is on the rise, especially in regions like Asia's stone belt, which includes Pakistan as well.

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Kidney Failure Secondary to Hereditary Xanthinuria due to a Homozygous Deletion of the XDH Gene in the Absence of Overt Kidney Stone Disease.

Nephron

August 2024

Group of Research and Development in Nephrology and Infectious Diseases, i3S - Institute for Health Research and Innovation, University of Porto, Porto, Portugal.

Hereditary xanthinuria (HXAN) is a rare metabolic disorder that results from mutations in either the xanthine dehydrogenase (XDH) or the molybdenum cofactor sulfurase genes (MOCOS), respectively defining HXAN type I and type II. Hypouricemia, hypouricosuria, and abnormally high plasma and urine levels of xanthine, causing susceptibility to xanthine nephrolithiasis and deposition of xanthine crystals in tissues, are the metabolic hallmarks of HXAN. Several pathogenic variants in the XDH gene have so far been identified in patients with HXAN type I, but the clinical phenotype associated with the whole deletion of the human XDH gene is unknown.

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Background: Evidence-based guidelines are published by urological organisations for various conditions, including urolithiasis. In this paper, we provide guidance on the management of kidney stone disease (KSD) and compare the American Urological Association (AUA) and European Association of Urologists (EAU) guidelines.

Methods: We evaluate and appraise the evidence and grade of recommendation provided by the AUA and EAU guidelines on urolithiasis (both surgical and medical management).

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In the acute diagnostics of a suspected nephroureterolithiasis, ultrasonography should be the examination modality of choice. In cases of suspected urolithiasis, unclear flank pain with fever or in cases of a solitary kidney, a noncontrast computed tomography (CT) scan should always subsequently be performed. If the sonography findings are inconclusive in pregnant women a magnetic resonance imaging (MRI) examination can be considered.

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Challenges in the management of hypercalcemia in pregnancy - Case report of two cases.

Case Rep Womens Health

March 2024

Department of Maternal Fetal Medicine, KK Women's and Children's Hospital, 100 Bukit Timah Road, 299899, Singapore.

Hypercalcemia in pregnancy is rare and can pose a great diagnostic challenge due to its asymptomatic presentation. It is associated with maternal complications such as urolithiasis, pancreatitis, renal insufficiency and preeclampsia, fetal complications such as growth restriction and intrauterine fetal demise, and neonatal complications such as neonatal hypocalcemia, tetany and hypoparathyroidism. Prompt diagnosis and treatment of the underlying cause of hypercalcemia is important.

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Preference for diagnosing and treating renal colic during pregnancy: a survey among Chinese urologists.

Sci Rep

February 2024

Department of Urology, The First Affiliated Hospital, Hengyang Medical School, University of South China, Hengyang, 421001, Hunan, China.

To explore the preference for diagnosing and treating renal colic during pregnancy among Chinese urologists. A questionnaire was designed using the Sojump platform. WeChat, the largest social networking platform in China, was used to distribute the questionnaire to urologists at hospitals of all levels in China.

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Article Synopsis
  • The article reviews literature on managing symptomatic physiological hydronephrosis during pregnancy and compares various intervention methods.
  • An extensive search through databases like PubMed revealed that conservative treatments, such as regular pain relief, positioning, and antibiotics, are generally preferred and effective for most patients.
  • While conservative management is usually the first choice, more invasive procedures like ureteric stent insertion or nephrostomy are reserved for a small number of cases where symptoms persist despite conservative care.
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Reno-protective effect of protocatechuic acid is independent of sex-related differences in murine model of UUO-induced kidney injury.

Pharmacol Rep

February 2024

Department of Oral Biology and Diagnostic Sciences, Dental College of Georgia, Augusta University, 1450 Laney Walker Blvd, CL2126, Augusta, GA, 30912, USA.

Article Synopsis
  • Obstructive nephropathy, often caused by urinary tract obstructions, can lead to chronic kidney disease (CKD) and exhibits sexual dimorphism, with males experiencing faster kidney function decline than females.
  • The study involved inducing unilateral ureteral obstruction (UUO) in male and female mice to analyze kidney injury and inflammation, using protocatechuic acid (PCA) as a potential treatment.
  • Results showed that UUO caused greater oxidative stress, inflammation, and apoptosis in males compared to females, but PCA significantly reduced kidney damage in both sexes, highlighting gender differences in response to kidney injury.
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Unlabelled: Actuality. The development of renal colic in pregnant women is one of the most common reasons for visiting a hospital that is not associated with obstetric pathology. Given the pharmacological and diagnostic limitations during gestation, the problem of expanding the renal cavitary system in pregnant women, as well as the choice of treatment tactics, remains a difficult clinical task.

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Introduction: This study aimed to evaluate the effect of coronavirus disease (COVID-19) on the patients' referral in the pregnant population and also investigate each treatment approach's advantages and disadvantages for acute renal colic in pregnancy.

Methods: In this retrospective study, we included all pregnant women with ureteral stones referred to a referral center between January 2019 and March 2021.

Results: Among 53 pregnant women, 18 (33.

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Ovarian torsion masquerading as a ureteral stone.

Am J Emerg Med

February 2024

Cleveland Clinic Akron General, Department of Emergency Medicine, 1 Akron GeneralAve., Akron, OH 44307, USA; Northeast Ohio Medical University, 4209 St. OH-44, Rootstown, OH 44272, USA. Electronic address:

Background: Abdominal pain is the most common complaint within the emergency department (ED) and has many varied etiologies. Some of these conditions can be medical emergencies, including ovarian torsion. While representing just 3% of gynecologic emergencies, ovarian torsion should be considered in all females presenting to the ED with abdominal or pelvic complaints.

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Noncontrast CT (NCCT) is the imaging study of choice for initial evaluation of patients with acute onset of flank pain and suspicion of stone disease without known prior stone disease. NCCT can reliably characterize the location and size of an offending ureteral calculus, identify complications, and diagnose alternative etiologies of abdominal pain. Although less sensitive in the detection of stones, ultrasound may have a role in evaluating for signs of obstruction.

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The incidence of stone disease has increased significantly in the past 30 years, with a reported prevalence of 11% of the U.S. population in 2022, up from 9% in 2012 and 5.

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Acute Pelvic Pain: Role of Imaging in the Diagnosis and Management.

Semin Ultrasound CT MR

December 2023

Department of Radiology, Baylor College of Medicine, Houston, TX. Electronic address:

Article Synopsis
  • Acute pelvic pain is a new symptom lasting less than 3 months, affecting 15%-24% of women and accounting for 20% of laparoscopies and 2%-10% of gynecologic visits.
  • Ultrasound is the preferred imaging method for diagnosing both gynecological and non-gynecological causes of pelvic pain, with CT scans used when ultrasound results are unclear.
  • Key gynecological causes include uterine and ovarian issues, while non-gynecological causes can involve bowel and urinary tract conditions; prompt diagnosis is crucial for conditions like ovarian torsion and ectopic pregnancy.
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Article Synopsis
  • * Out of 100 reviewed patients, 78 were analyzed, revealing that those who underwent PCN had the highest total mean radiation exposure (286.9 mGy) and required significantly more procedures compared to the other two interventions.
  • * The results indicated that PCN not only led to higher radiation exposure but also resulted in more complications, with over 40% of PCNs experiencing dysfunction and an average exchange period of 16.5 days.
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Purpose Of Review: Management of stone disease in pregnancy poses a challenge for all healthcare professionals involved in their care. During pregnancy, there is an increase in the incidence of urolithiasis. Major technological and procedural advances have been seen in the last decade for endoscopic management of urolithiasis.

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The substantial reduction of radiation exposure using (ultra-)low dose programs in native computed tomographic imaging has led to considerable changes in imaging diagnostics and treatment planning in urolithiasis in recent years. In addition, especially in Germany, ultrasound diagnostics is highly available in terms of equipment and with increasing expertise. This can largely replace the previous radiation-associated procedures in emergency and follow-up diagnostics, but also in intraoperative imaging, e.

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Management of urolithiasis in pregnancy.

Curr Urol

March 2023

Urology Department, Lister Hospital, East and North Hertfordshire NHS Trust, Stevenage, UK.

Urolithiasis is the most common cause of nonobstetric abdominal pain, resulting in 1.7 admissions per 1000 deliveries. Urolithiasis most commonly occurs in the second and third trimesters, with an incidence between 1:125 and 1:2000.

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