CSF Proteomics of Patients with Hydrocephalus and Subarachnoid Haemorrhage.

Background: The pathophysiology of brain injury following aneurysmal subarachnoid haemorrhage (SAH) is associated with numerous mediators. The aim of the study is to analyse protein changes after SAH in cerebrospinal fluid (CSF) using mass spectrometry (MS).

Methods: CSF samples were obtained from forty-four control subjects, seven good outcome and ten poor outcome SAH patients.