10,361 results match your criteria: "Poznan University of Medical Sciences[Affiliation]"
Med Sci Monit
December 2024
Independent Laboratory of Minimally Invasive Gynecology and Gynecological Endocrinology, Medical University of Lublin, Lublin, Poland.
Polycystic ovary syndrome (PCOS) is associated with several mild metabolic disorders, including insulin resistance (IR), obesity, and dyslipidemia, as well as with some more severe ones, including type 2 diabetes mellitus, non-alcoholic fatty liver disease (NAFLD), and cardiovascular disease. Clinically, mild metabolic complications of PCOS such as IR or lipid metabolism disorders are the predictors of these more severe ones. So far, there is no reliable single marker that enables defining metabolic risk in patients with PCOS.
View Article and Find Full Text PDFJ Infect Public Health
December 2024
Department of Infectious Diseases and Child Neurology, Institute of Paediatrics, Poznan University of Medical Sciences, Poland.
Background: Group A Streptococci (GAS) may cause infections of the pharynx and soft tissues and invasive infections in children (iGAS). A significant increase in severe iGAS infections has been reported in Europe since the fall of 2022.
Objectives: This retrospective study aims to analyse clinical data of children with invasive and non-invasive GAS infections in the post-COVID-19 pandemic era, searching for predisposing factors to developing invasive infections.
Eur J Public Health
December 2024
Department of Anesthesiology and Intensive Therapy, Silesian Centre for Heart Diseases in Zabrze, Medical University of Silesia, Zabrze, Poland.
The discontinuation of futile therapy is increasingly discussed in Polish clinical practice. Given the need to ensure patient well-being, it is essential to consider whether all clinical options resulting from medical progress should be used for every patient and on what grounds decisions to limit therapy should be based. The aim of our study was to determine the opinions of Polish medical doctors on this topic.
View Article and Find Full Text PDFExp Gerontol
December 2024
Department of Physiology and Aging, University of Florida, Gainsville, FL, USA. Electronic address:
This special issue of the Journal of Experimental Gerontology explores the dynamic interplay between microbiomes and aging-related conditions. The four selected studies highlight the role of microbiota in Alzheimer's disease, cancer immunotherapy, myocardial infarction and tryptophan metabolism, providing insights into how microbiomes influence health and disease in aging. These studies underscore the potential for microbiome-targeted interventions to mitigate aging-related disorders and improve the quality of life for older adults.
View Article and Find Full Text PDFCurr Probl Cardiol
December 2024
Department of Pediatric Endocrinology and Rheumatology, Institute of Pediatrics, Poznan University of Medical Sciences, 60-572 Poznan, Poland.
Diabetic cardiomyopathy (DCM) represents a distinct form of heart disease characterized by structural and functional alterations in the myocardium, occurring in the absence of other cardiac conditions. This review delves into the pathophysiological mechanisms underlying myocardial fibrosis in DCM, highlighting the pivotal role of fibroblast transdifferentiation into myofibroblasts. We examine the interplay between hyperglycemia, immune cell activation, and neurohumoral signaling pathways, with a particular focus on the transforming growth factor-beta (TGF-β) signaling cascade and its contributions to collagen deposition and cardiac dysfunction.
View Article and Find Full Text PDFDent Med Probl
December 2024
Department of Prosthetic Dentistry and Gerodontology, Poznan University of Medical Sciences, Poland.
Background: Ceramic endosseous implant coatings have gained esteem due to their favorable osteoinductive and osteoconductive properties. However, such a layer may be prone to failure under in vivo conditions, which necessitates its modification.
Objectives: The aim of the present study was to modify an electrodeposited hydroxyapatite (HA) coating on titanium (Ti) with ultrashort-pulsed lasers for the incorporation of the ceramic into the sample surface and the texturing of the metal surface.
Dent Med Probl
December 2024
Department of Radiology, 10th Military Research Hospital and Polyclinic, Bydgoszcz, Poland.
Background: Patients are increasingly turning to Internet platforms for health-related information. An example is YouTube, one of the largest media-sharing networks in the world.
Objectives: The aim of the present study was to assess the informational value of YouTube videos on the treatment of bruxism with botulinum toxin, a procedure that is becoming increasingly popular in the field of dentistry.
Acta Ophthalmol
December 2024
Department of Ophthalmology, New Civil Hospital, Strasbourg University Hospital, FMTS, Strasbourg, France.
Purpose: To report national practices and recent progress in competency-based medical education (CBME) implementation in ophthalmology across European countries.
Methods: A 30-question online survey was emailed to European Union of Medical Specialists (UEMS) ophthalmology section delegates, European Board of Ophthalmology Diploma (EBOD) examiners and presidents of ophthalmology societies affiliated with UEMS/EBO.
Results: A total of 230 ophthalmologists with an average age of 54.
J Mov Disord
December 2024
Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
Non-motor fluctuations (NMF) in Parkinson's disease (PD) significantly affect patients' well-being. Despite being identified over two decades ago, NMF remain largely under-recognized, under-treated, and poorly understood. While they are often temporally associated with motor fluctuations (MF) and can share common risk factors and pathophysiologic mechanisms, NMF and MF are currently considered distinct entities.
View Article and Find Full Text PDFAdv Clin Exp Med
December 2024
Department of Clinical Psychology, Poznań University of Medical Sciences, Poland.
Background: Dysphagia, prevalent in 90% of children with neurological disorders, poses risks of medical complications and is associated with cognitive and psychosocial challenges. The absence of the sucking-swallowing reflex and variations in the gag reflex contribute to feeding difficulties.
Objectives: This study focuses on examining the impact of the gag reflex on the masticatory system structure in children with cerebral palsy, aiming to assess its significance.
Background: Patient-reported outcome measures (PROMs) have become crucial in assessing cataract surgery, especially with increasing patient expectations. The RayPro database offers a platform for tracking PROMs after surgery. The purpose of this study is to investigate determinants of patient satisfaction following cataract surgery by analysing PROMs.
View Article and Find Full Text PDFJ Appl Genet
December 2024
Department of Molecular Neurooncology, Institute of Bioorganic Chemistry Polish Academy of Sciences, Zygmunta Noskowskiego 12/14, 61-704, Poznan, Poland.
To find a distinct non-coding RNA characteristic for idiopathic uveitis in the pediatric population. To explore the autoimmune-related miRNA expression profile in pediatric patients with idiopathic uveitis (IU) and juvenile idiopathic arthritis-associated uveitis (JIA-AU) and find a common molecular background for idiopathic uveitis and other autoimmune diseases. The expression levels of miRNAs were analyzed by quantitative real-time PCR using serum samples from patients with idiopathic uveitis (n = 8), juvenile idiopathic arthritis-associated uveitis (n = 7), and healthy controls.
View Article and Find Full Text PDFPediatr Blood Cancer
December 2024
Department of Pediatric Oncology, Hematology and Transplantology, Poznan University of Medical Sciences, Poznan, Poland.
Background: Enhancing therapy outcomes in pediatric oncology and hematology relies on robust epidemiological surveillance. This study aimed to estimate cancer stage-related survival in pediatric patients with lymphoma and solid tumors by assessing changes over time and identifying spatial clustering of patients diagnosed at advanced stages.
Procedure: This retrospective observational cohort study included pediatric cancer patients treated in a single Greater Poland center, constituting 9% of Polish children from 2004 to 2017.
Neurol Neurochir Pol
December 2024
Department of Neurology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia in Katowice, Zabrze, Poland.
Introduction: An expert panel of the Section of Multiple Sclerosis and Neuroimmunology of the Polish Neurological Society has developed principles for the management of neuromyelitis optica spectrum disorders (NMOSD). These principles are based on expert opinion and data from the literature published up to May 2023. Recommendations were developed based on the results of the most recent clinical trials, guidelines of foreign and international scientific societies, and the authors' clinical experience.
View Article and Find Full Text PDFDent Med Probl
December 2024
Chair of Practical Clinical Dentistry, Department of Diagnostics, Poznan University of Medical Sciences, Poland.
Background: The inferior alveolar canal (IAC) is a fundamental mandibular structure. It is important to conduct a precise pre-surgical evaluation of the IAC to prevent complications. Recently, the use of artificial intelligence (AI) has demonstrated potential as a valuable tool for dentists, particularly in the field of oral and maxillofacial radiology.
View Article and Find Full Text PDFCochrane Database Syst Rev
December 2024
Paediatrics, Department of Clinical Sciences Lund, Lund University, Skåne University Hospital, Lund, Sweden.
Background: Peripartum asphyxia affects three to five per 1000 live births, with moderate or severe hypoxic ischemic encephalopathy (HIE) occurring in 0.5 to 1 per 1000 live births, and is associated with high mortality and morbidity. Therapeutic hypothermia is an effective treatment, but alternative therapies such as acupuncture are also used.
View Article and Find Full Text PDFCochrane Database Syst Rev
December 2024
Paediatrics, Department of Clinical Sciences Lund, Lund University, Skåne University Hospital, Lund, Sweden.
This is a protocol for a Cochrane Review (intervention). The objectives are as follows: To assess the benefits and harms of clustering of care activities for promoting development and preventing morbidity in preterm infants.
View Article and Find Full Text PDFJ Pediatr Orthop
December 2024
Spine Disorders and Pediatric Orthopedics, University of Medical Sciences.
Background: The effectiveness and safety of the pericapsular nerve group (PENG) block and lumbar erector spinae plane block (ESPB) in pediatric hip surgeries is limited mainly to case reports. This study assessed the efficacy of ultrasound-guided PENG block versus lumbar ESPB under spinal anesthesia.
Methods: Ninety patients aged 2 to 7 years, ASA I-III scheduled for hip surgery were randomly assigned to 3 equal groups, each receiving the PENG block group (n=30), the ESPB group (n=30), or the control group (n=30).
Pediatr Cardiol
December 2024
Department of Cardiovascular Sciences, KU Leuven, Leuven, Belgium.
Patients with a Fontan circulation are at risk for chronic kidney disease (CKD), which is defined as persistently reduced glomerular filtration rate (GFR) <60ml/min/1.73 or elevated marker of kidney injury such as urinary albumin-to-creatinine ratio (UACR) >30mg/g. We determined the prevalence of albuminuria in patients with a Fontan circulation.
View Article and Find Full Text PDFCochrane Database Syst Rev
December 2024
Division of Neonatal-Perinatal Medicine, Department of Pediatrics, Larner College of Medicine at the University of Vermont, Burlington, Vermont, USA.
This is a protocol for a Cochrane Review (intervention). The objectives are as follows: To evaluate the benefits and harms of financial incentives for improving family engagement on family members of neonates receiving hospitalized care.
View Article and Find Full Text PDFJ Clin Med
December 2024
Department of Cardiac Surgery, Vascular and Endovascular Surgery, and Heart Transplantology, Silesian Centre for Heart Diseases, Medical University of Silesia, 40-055 Zabrze, Poland.
The aim of this study was to evaluate the impact of coronary bypass surgery (CABG) on long-term mortality, comparing survival rates to those of the general population in Poland. The study was based on the Polish National Register of Cardiothoracic Surgical Procedures (KROK). Between January 2009 and December 2019, 133,973 patients underwent CABG.
View Article and Find Full Text PDFJ Clin Med
December 2024
Tricomed S.A., Świętojańska 5/9, 93-493 Lodz, Poland.
The prevalence of POP in women ranges from 30-40%, with 10-20% requiring surgical intervention. Annually, over 225,000 surgical procedures for POP are performed in the United States. The severity of prolapse is assessed using the four-stage POP-Q system, which facilitates clinical research by providing a standardized measure of defect severity.
View Article and Find Full Text PDFJ Clin Med
December 2024
Department of Traumatology, Orthopaedics and Hand Surgery, Poznan University of Medical Sciences, 61-545 Poznań, Poland.
Damage to the upper trunk of the brachial plexus, often caused by high-energy trauma, leads to significant functional impairment of the upper limb. This injury primarily affects the C5 and C6 roots, resulting in paralysis of muscles critical for shoulder and elbow function. If spontaneous nerve regeneration does not occur within 3-6 months post-injury, surgical intervention, including nerve transfers, is recommended to restore function.
View Article and Find Full Text PDFJ Clin Med
December 2024
Department of Dental Surgery, Periodontology and Oral Mucosa Diseases, Poznan University of Medical Sciences, 70 Bukowska St., 60-812 Poznań, Poland.
Lichen planus (LP) is a chronic, recurrent mucocutaneous inflammatory disease that develops due to a disturbed immunological response triggered by endogenous and exogenous factors. To evaluate clinical presentation, demographic characteristics, and risk factors in a cohort of Polish patients with oral lichen planus (OLP). Medical records of 186 patients with OLP referred to the student outpatient clinic in Poznań University of Medical Sciences from 2013 to 2023 were analyzed in order to establish clinical presentation, patient's demographic characteristics, and risk factors for OLP.
View Article and Find Full Text PDFJ Clin Med
December 2024
Department of Gynaecology, Division of Gynaecology, Poznan University of Medical Sciences, 61-701 Poznan, Poland.
This study aims to evaluate the prevalence of premenstrual syndrome (PMS) among Polish adolescents and explore its associations with mental health outcomes, lifestyle factors, and risk behaviours. Additionally, it seeks to examine the impact of PMS on quality of life, contributing to the foundation for initiatives that enhance adolescent menstrual health. This research is part of the POLKA 18 study, a youth-led cross-sectional survey conducted between April and December 2019.
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