1,122 results match your criteria: "Postpolio Syndrome"

Purpose: Total knee arthroplasty (TKA) in patients with sequelae of poliomyelitis is a surgical challenge due to muscle weakness, bone deformities or post-polio syndrome (PPS). Few data exist to determine the factors contributing to poor functional results. This study aimed: (1) to describe a cohort of patients with poliomyelitis sequelae who underwent TKA; (2) to examine risk factors for poor functional outcome.

View Article and Find Full Text PDF

Aim: It is unclear if individuals with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) with family histories of ME/CFS differ from those with ME/CFS without this family history. To explore this issue, quantitative data from patients with ME/CFS and controls were collected, and we examined those with and without family histories of ME/CFS.

Methods: The samples included 400 patients with ME/CFS, and a non-ME/CFS chronic illness control group of 241 patients with multiple sclerosis (MS) and 173 with post-polio syndrome (PPS).

View Article and Find Full Text PDF

The Lateral Corticospinal Tract Sign: An MRI Marker for Amyotrophic Lateral Sclerosis.

Radiology

September 2024

From the Translational Imaging in Neurology (ThINk), Department of Biomedical Engineering (M.J.W., E.K., L.S., M. Weigel, C.G., R.S.), Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB) (M.J.W., E.K., L.S., M. Weigel, C.G., R.S.), Department of Biomedical Engineering (M. Weigel, C.W., O.B.), Institute of Forensic Medicine, Department of Biomedical Engineering (D.N., E.S., C.L.), and Department of Biomedicine (M.S.), University of Basel, Basel, Switzerland; Neurology Clinic and Policlinic, Department of Clinical Research (E.K., L.S., M. Weigel, M.D., N.N., C.G., K.S., M.S., R.S.), Division of Radiological Physics, Department of Radiology (M. Weigel, C.W., T.H., P.M., O.B.), Department of Pathology, Institute of Medical Genetics and Pathology (N.D.), and Department of Theragnostics, Clinic of Radiology and Nuclear Medicine, Division of Diagnostic and Interventional Neuroradiology (J.L.), and Department of Neurology (R.S.), University Hospital Basel, University of Basel, Petersgraben 4, 4031 Basel, Switzerland; Institute of Neuropathology, Neurocenter, University Medical Center Freiburg, University of Freiburg, Freiburg, Germany (M.D.); Institute of Forensic Medicine, Health Department Basel-Stadt, Basel, Switzerland (D.N., E.S., C.L.); and Neuromuscular Diseases Unit/ALS Clinic, Kantonsspital St Gallen, St Gallen, Switzerland (C.N., N.B., M. Weber).

Background Radially sampled averaged magnetization inversion-recovery acquisition (rAMIRA) imaging shows hyperintensity in the lateral corticospinal tract (CST) in patients with motor neuron diseases. Purpose To systematically determine the accuracy of the lateral corticospinal tract sign for detecting patients with amyotrophic lateral sclerosis (ALS) at rAMIRA MRI. Materials and Methods This study included prospectively acquired data from participants in ALS and other motor neuron disease imaging studies at the University Hospital Basel, Switzerland.

View Article and Find Full Text PDF

Post-polio syndrome (PPS) affects former polio patients, manifesting decades after initial infection with progressive symptoms like pain, fatigue, and muscle weakness. Diagnosis relies on the clinical criteria and exclusion of other probable causes. The purpose of this study is to determine the scope and new diagnostic value of magnetic resonance imaging (MRI) in identifying muscle involvement in PPS and distinguishing it from prior poliomyelitis (PPM).

View Article and Find Full Text PDF
Article Synopsis
  • Post-polio syndrome (PPS) causes muscle problems, pain, and sadness for people who had polio in the past.
  • A study tested special treatments called REAC to help people with PPS feel better and have a better life.
  • The treatments helped reduce pain and feelings of sadness, anxiety, and stress, making the patients feel much better overall.
View Article and Find Full Text PDF

Validity of Cardiopulmonary Exercise Testing for Assessing Aerobic Capacity in Neuromuscular Diseases.

Arch Phys Med Rehabil

October 2024

Department of Rehabilitation Medicine, Amsterdam UMC location, University of Amsterdam, Amsterdam; Amsterdam Movement Sciences, Rehabilitation & Development, Amsterdam, The Netherlands. Electronic address:

Objectives: To determine the content validity of cardiopulmonary exercise testing (CPET) for assessing peak oxygen uptake (VO) in neuromuscular diseases (NMD).

Design: Baseline assessment of a randomized controlled trial.

Setting: Academic hospital.

View Article and Find Full Text PDF

Post-polio syndrome - somatosensory dysfunction and its relation to pain: a pilot study with quantitative sensory testing.

J Rehabil Med

June 2024

Department of Rehabilitation Medicine, Danderyd University Hospital, Stockholm, Sweden; Department of Clinical Sciences, Karolinska Institutet, Stockholm, Sweden.

Article Synopsis
  • - The study aimed to investigate sensory dysfunction in six patients with post-polio syndrome and chronic pain using Quantitative Sensory Testing.
  • - Tests revealed that most patients (5 out of 6) exhibited heightened sensitivity to mechanical pain, indicating somatosensory issues when compared to standard reference values.
  • - Findings suggest a potential link between post-polio syndrome and generalized somatosensory dysfunction, as no significant differences were noted between more and less affected body parts.
View Article and Find Full Text PDF
Article Synopsis
  • * Findings revealed that over half of the PPS patients experienced CS, with a high percentage reporting severe symptoms and lower quality of life compared to those without CS.
  • * The presence of CS correlated with increased fatigue, pain, and polio-related impairments, suggesting that addressing CS could help improve outcomes for affected individuals.
View Article and Find Full Text PDF
Article Synopsis
  • Chilaiditi syndrome occurs when the interpositioning of the colon between the liver and diaphragm leads to complications like respiratory issues or bowel obstruction.
  • A 70-year-old man with multiple health issues presented with symptoms including shoulder pain and dizziness, which were initially linked to dehydration.
  • Imaging revealed a Chilaiditi sign and possible bowel obstruction; despite treatment, his condition improved primarily with hydration and bowel rest, illustrating the complexities of managing this syndrome alongside other chronic conditions.
View Article and Find Full Text PDF

Introduction: People with post-polio syndrome usually have some residual deformities. Genu recurvatum is very commonly seen in such cases which are a risk factor for anterior cruciate ligament (ACL) injury due to the altered biomechanics. To the best of our knowledge, this is the first report in literature presenting ACL reconstruction in a limb with genu recurvatum deformity treated with supracondylar osteotomy.

View Article and Find Full Text PDF

COVID-19 and the Postviral Syndrome of Long COVID: Where We Have Come from and Where We Are Going.

Health Soc Work

April 2024

PhD, MSW, LCSW, is professor and associate dean for faculty development, School of Social Work, University at Buffalo, Buffalo, NY, USA.

View Article and Find Full Text PDF

Segmental areas of denervation in post-polio syndrome.

Arq Neuropsiquiatr

February 2024

Universidade Federal de São Paulo, Escola Paulista de Medicina, Departamento de Neurologia e Neurocirurgia, São Paulo SP, Brazil.

View Article and Find Full Text PDF
Article Synopsis
  • Post-stroke fatigue (PSF) is common among stroke survivors and can significantly impede their recovery, with current treatments often proving ineffective.
  • This study aims to evaluate the impact of transcranial direct current stimulation (tDCS) on alleviating fatigue in stroke patients, involving 156 participants in a double-blind randomized control trial.
  • The primary measure of success will be changes in fatigue severity assessed using a modified scale at various points during and after treatment, comparing results between an active tDCS group and a control group receiving sham treatment.
View Article and Find Full Text PDF
Article Synopsis
  • People with late effects of polio (LEoP) often require rehabilitation, but there's limited understanding of how effective interdisciplinary rehabilitation is for them.
  • A study measured the changes in performance and satisfaction in daily activities before and after rehabilitation in 102 LEoP participants, using the Canadian Occupational Performance Measure (COPM).
  • The results showed significant improvements in performance and satisfaction scores, indicating that interdisciplinary rehabilitation can be beneficial, though a portion of participants did not experience changes or had decreased ratings.*
View Article and Find Full Text PDF
Article Synopsis
  • Poliomyelitis is a serious disease that affects millions of people worldwide, and many survivors can experience ongoing problems like muscle weakness and fatigue, known as post-poliomyelitis syndrome (PPS).* -
  • Researchers wanted to learn more about the immune system's role in PPS by comparing certain immune cells and factors between people with PPS and healthy controls.* -
  • The study found that while the two groups were similar in several areas, PPS patients had higher levels of a specific enzyme in their blood, but overall, their immune responses were similar to healthy individuals.*
View Article and Find Full Text PDF

[Congenital malformations of the brain misinterpreted as sequelae of poliomyelitis].

Z Gerontol Geriatr

August 2024

Geriatrisches Zentrum, Evangelisches Krankenhaus Göttingen-Weende, An der Lutter 24, 37075, Göttingen, Deutschland.

Article Synopsis
View Article and Find Full Text PDF

Post-Polio Syndrome (PPS) is a chronic condition characterized by the emergence of new symptoms and functional decline in individuals who previously had polio. Despite advances in medical understanding, management of PPS remains challenging. This study aimed to evaluate the use of neurobiological modulation treatments using Radio Electric Asymmetric Conveyer (REAC) technology on fatigue and muscle strength.

View Article and Find Full Text PDF

Background: Although common in lung cancer, somatic epidermal growth factor receptor () mutations are rarely found in colorectal cancer, occurring in approximately 3% of cases. Treatment with anti-EGFR antibodies is commonplace, but tyrosine kinase inhibitors are not standard treatments in colorectal cancer. Here we report a case of sustained response to osimertinib in a colorectal cancer patient with an T790M mutation on cell-free DNA analysis.

View Article and Find Full Text PDF

The Role of Epigenetics in Accelerated Aging: A Reconsideration of Later-Life Visual Loss After Early Optic Neuropathy.

J Neuroophthalmol

March 2024

Department of Ophthalmology and the Neuro-Ophthalmology Service (JFR), Massachusetts Eye and Ear and the Harvard Medical School, Boston, Massachusetts; Avedisian and Chobanian School of Medicine (MPS), Boston University, Boston, Massachusetts; Department of Ophthalmology (MPS, DK, BRK), Harvard Medical School, Schepens Eye Research Institute of Mass Eye & Ear, Boston, Massachusetts; Department of Biology (YRL), Whitehead Institute for Biomedical Sciences, MIT, Cambridge, Massachusetts; and Paul F. Glenn Center for Biology of Aging Research (DAS), Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, Massachusetts.

Background: In 2005, we reported 3 patients with bilateral optic nerve damage early in life. These patients had stable vision for decades but then experienced significant bilateral vision loss with no obvious cause. Our hypothesis, novel at that time, was that the late decline of vision was due to age-related attrition of retinal ganglion cells superimposed on a reduced neuronal population due to the earlier injury.

View Article and Find Full Text PDF

[Interdisciplinary multimodal pain therapy in postviral syndromes and ME/CFS : Features, pitfalls and model concept].

Schmerz

June 2024

Interdisziplinäre Schmerztagesklinik der München Klinik Schwabing, Klinik für Anästhesiologie, Kinderanästhesiologie und Operative Intensivmedizin, München Klinik Schwabing, München, Deutschland.

Background: Multimodal pain therapy usually take place in the context of group therapy lasting several weeks and is based on a generally activating approach. Due to the specificity of stress intolerance with postexertional malaise (PEM) in patients with postviral syndromes, physical as well as psychological overload must be urgently avoided in these cases; however, these aspects can only be insufficiently considered in current medical pain therapy concepts.

Methods: Summary of the current literature and presentation of clinical characteristics as well as presentation of a model project for a multimodal pain therapy in postviral syndromes with PEM.

View Article and Find Full Text PDF
Article Synopsis
  • Fatigue from neurological conditions significantly lowers quality of life, and this review looks at using transcranial direct current stimulation (tDCS) as a potential treatment option.
  • A comprehensive literature search identified various studies where tDCS was applied to manage fatigue in conditions like multiple sclerosis, stroke, and Parkinson's disease, with the majority showing positive results in reducing fatigue.
  • While most studies reported improvements, common side effects included tingling, headaches, and itching, suggesting that while tDCS is promising, further exploration of its efficacy and safety is needed.
View Article and Find Full Text PDF
Article Synopsis
  • - Pulmonary hernias usually occur due to trauma, surgeries, or congenital defects, with spontaneous lung hernias being very rare, especially in post-polio syndrome cases.
  • - Post-polio syndrome arises 30-40 years after polio infection and leads to symptoms like muscle weakness, fatigue, and atrophy.
  • - The case report discusses a post-polio patient who developed a spontaneous lung hernia without prior injury and includes details on imaging, diagnosis, and management of such hernias.
View Article and Find Full Text PDF