15,033 results match your criteria: "Postpartum Hemorrhage"

Midwife-Led Versus Obstetrician-Led Perinatal Care for Low-Risk Pregnancy: A Systematic Review and Meta-Analysis of 1.4 Million Pregnancies.

J Clin Med

November 2024

Department of Family and Community Medicine and Medical Education, College of Medicine, Taibah University, Madinah 42353, Saudi Arabia.

The optimum model of perinatal care for low-risk pregnancies has been a topic of debate. Obstetrician-led care tends to perform unnecessary interventions, whereas the quality of midwife-led care has been subject to debate. This review aimed to assess whether midwife-led care reduces childbirth intervention and whether this comes at the expense of maternal and neonatal wellbeing.

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Article Synopsis
  • Uterine arteriovenous malformations (UAVMs) are a rare cause of heavy bleeding after childbirth, often linked to placenta accreta spectrum (PAS).
  • A case study highlighted a woman with PAS who experienced significant bleeding post-delivery and required several treatments, including uterine artery embolization, which proved effective.
  • The study suggests that UAVMs may arise from residual PAS tissue and emphasizes the importance of preserving fertility while managing severe bleeding, avoiding more drastic measures like hysterectomy.
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Article Synopsis
  • This study analyzed the outcomes of singleton pregnancies from frozen embryo transfer (FET) cycles using data from over 44,000 women in South Korea, focusing on different embryo transfer methods.
  • It found that artificial cycle-FET (AC-FET) had higher risks of complications like hypertensive disorders compared to natural cycle-FET (NC-FET), while stimulated cycle-FET (SC-FET) offered lower miscarriage rates but had some increased risks as well.
  • The overall results suggest that NC-FET is the safest approach for both mothers and babies, with SC-FET being a reasonable alternative when NC-FET isn't possible.
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The Impact of Pregestational Diabetes on Maternal Morbidity and Mortality: Trends, Challenges and Future Directions.

Am J Perinatol

November 2024

Department of Maternal Fetal Medicine, Inova Fairfax Medical Campus, Falls Church, United States.

Article Synopsis
  • * Pregestational diabetes affects 1-2% of pregnancies and is associated with higher risks of severe complications, contributing to 17% of the increase in maternal mortality from 1997 to 2012.
  • * There are significant disparities in pregnancy outcomes, particularly affecting non-Hispanic Black women, who are 2.5 times more likely to experience maternal mortality, highlighting the need for targeted research and interventions to improve care and reduce risks.
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Article Synopsis
  • The study aimed to assess the reliability of placental volume and MRI indicators in predicting placenta accreta spectrum (PAS) and severe peripartum hemorrhage (SPPH) in women with complete placenta previa.
  • Involving 216 pregnant women, data were analyzed by two radiologists who independently reviewed MRIs of 150 cases delivered in the third trimester, focusing on placental volume, cervical canal length, and dilation.
  • Results indicated significant risk factors for PAS and SPPH, particularly lower cervical canal length and increased cervical dilation, confirming cervical canal length as a key independent predictor for both conditions.
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  • A multinational trial, NiPPeR, tested a nutritional formulation vs. a standard supplement in pregnant women and aimed to improve maternal health and pregnancy outcomes.
  • The primary outcome showed no difference in gestational glycemia, but the intervention resulted in significant benefits, such as reduced preterm delivery rates and shorter conception time for overweight women.
  • Overall, the study suggests that preconception nutritional interventions can positively influence both maternal health and long-term outcomes for infants, potentially reducing the risk of chronic diseases later in life.
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Article Synopsis
  • Caesarean sections (CS) are the most common major surgery worldwide, but they pose significant risks for maternal mortality, especially in low-resource settings like Malawi, where a study reviewed maternal deaths from 2020 to 2022.
  • The study found that over half of maternal deaths (51.8%) occurred after CS, with women undergoing CS being five times more likely to die compared to those who delivered vaginally, due to causes like postpartum hemorrhage, eclampsia, and infection.
  • Health system issues contributed to these deaths, including delayed treatment and inadequate monitoring, indicating a pressing need to enhance the safety and management of CS in healthcare practices.
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Abnormal placental development induced by repeated cesarean sections: Investigating an animal model of placenta accreta spectrum disorders.

Placenta

December 2024

Department of Obstetrics and Gynecology and Reproductive Medicine, Peking University First Hospital, Beijing, China; Beijing Key Laboratory of Maternal Fetal Medicine of Gestational Diabetes Mellitus, Beijing, China. Electronic address:

Article Synopsis
  • Placenta accreta spectrum (PAS) is a serious health issue that can cause severe bleeding after childbirth, often requiring emergency surgery; however, the underlying mechanisms are not well understood due to limitations in animal research.
  • In this study, researchers performed multiple cesarean sections on pregnant mice to create a model that mimics the risk factors for PAS, examining various aspects of pregnancy outcomes and placental health.
  • Results showed that repeated cesarean sections led to significant complications in pregnancy, including abnormal placental development and fetal issues, indicating that this mouse model closely resembles the clinical features of PAS and can be useful for future research and prevention strategies.
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Maternal and neonatal outcomes of prolonged second stage of labor with delayed pushing: A study of French Perinatal practices before and after guideline changes.

Eur J Obstet Gynecol Reprod Biol

January 2025

Université Paris Cité, Institut Santé des femmes, U1153, Centre of Research In Epidemiology and Statistics (CRESS), Obstetrical, Perinatal and Paediatric Epidemiology Research Team (EPOpé), INSERM, INRAE, Paris, France; Port-Royal Maternity Unit, Assistance Publique-Hôpitaux de Paris, Hôpital Cochin, FHU préma, 123 Bd de Port-Royal, 75014 Paris, France.

Article Synopsis
  • - The study aimed to assess the rates of prolonged second stage of labor in France and its association with postpartum complications before and after updated labor guidelines in 2021.
  • - Analysis of data from the French National Perinatal Surveys revealed that the incidence of prolonged second stage increased significantly in 2021, particularly among nulliparous and multiparous patients.
  • - The research indicated a rise in severe postpartum hemorrhage rates associated with prolonged second stage, especially in nulliparous and multiparous women, while severe perineal tears and neonatal morbidity remained largely unchanged.
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Arteriovenous malformation associated with trophoblastic retention post-cesarean section: A case report and review.

Int J Surg Case Rep

December 2024

Department of Gynecology-Obstetrics, Mohammed V Military Teaching Hospital, Faculty of Medicine and Pharmacy of Rabat, University Mohammed V, Rabat, Morocco.

Article Synopsis
  • * A case involved a 32-year-old woman diagnosed with a uterine AVM after experiencing bleeding post-miscarriage, confirmed through ultrasound and MRI, leading to successful treatment involving embolization and tissue removal.
  • * This report highlights the importance of using non-invasive imaging techniques like ultrasound and MRI for early diagnosis of uterine AVMs, allowing for conservative treatment options that help preserve fertility in women of childbearing age.
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Evidence-based obstetric guidance in the setting of a global intravenous fluid shortage.

Am J Obstet Gynecol MFM

December 2024

Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, University of North Carolina, Chapel Hill, NC (Heerboth, Trawick, Coviello, and Quist-Nelson).

Article Synopsis
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Impact of scaling up health intervention coverage on reducing maternal mortality in 26 low- and middle-income countries: A modelling study.

J Glob Health

November 2024

Department of Maternal and Child Health, School of Public Health, Peking University, National Health Commission Key Laboratory of Reproductive Health, Peking University Health Science Center-Weifang Joint Research Center for Maternal and Child Health, Beijing, China.

Background: Prioritising actions is urgently needed to address the stagnation of the global maternal mortality ratio (MMR). As most maternal deaths occur in low- and middle-income countries (LMICs), we aimed to assess the impact of scaling up health intervention coverage on reducing MMR under four scenarios for 26 LMICs.

Methods: We conducted a modelling study to estimate the MMR and additional maternal lives saved by intervention by 2030 for 26 LMICs using the Lives Saved Tool (LiST).

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Risk Factors for Primary Postpartum Hemorrhage in Vaginal Delivery.

J Nepal Health Res Counc

October 2024

Department of Obstetrics and Gynecology, Paropakar Maternity and Womens Hospital, Kathmandu.

Article Synopsis
  • Postpartum hemorrhage (PPH) is a life-threatening emergency mostly affecting women in developing countries, requiring quick diagnosis and management due to its role as a leading cause of maternal mortality.
  • The study aimed to identify various risk factors associated with primary PPH at Paropakar Maternity and Women’s Hospital over a 3-month period, analyzing 72 patients with term pregnancies who experienced PPH.
  • Results showed a 3% incidence rate of primary PPH, primarily affecting women aged 20-24 and those with a gravidity of 2 to 3, with risk factors such as hypertensive disorders, anemia, and multiple pregnancies identified in some cases.
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Background: Obstetric patient blood management (PBM) strategies were used at Corniche Hospital in 2018, initially focusing on minimizing bleeding, with other clinical strategies implemented incrementally. This study assesses program outcomes in patients with major obstetric hemorrhage of 2000 mL or greater.

Methods: A retrospective study of 353 women admitted to The Corniche Hospital between 2018 and 2023 who experienced major obstetric hemorrhage of 2000 mL or greater.

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Gestational Diabetes and Analysis of Maternal and Fetal Outcomes Among Pregnant Women: A Cross-Sectional Study.

J Obstet Gynaecol India

October 2024

Department of Obstetrics and Gynaecology, KS Hegde Medical Academy (KSHEMA), Justice KS Hegde Charitable Hospital, NITTE (Deemed to be University), Mangalore, Karnataka 575018 India.

Purpose Of The Study: To determine the occurrence of gestational diabetes mellitus and analyze the maternal and fetal outcomes among pregnant women.

Methods: A prospective cross-sectional study was conducted for a duration of 7 months in the Department of Gynecology and Obstetrics at tertiary care hospital where 518 pregnant women participants of age above 18 years who had come for labor and undergone DIPSI (diabetes in pregnancy study of India) test were included in the study after the ethical clearance and obtaining written informed consent, whereas pregnant women with pre-existing diabetes mellitus and on other medication that alter glucose metabolism were excluded from the study.

Results: The occurrence of GDM was found to be 15.

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National-level assessment of gestational carrier pregnancies in the United States.

J Assist Reprod Genet

November 2024

Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, University of Southern California, Los Angeles, CA, USA.

Article Synopsis
  • - The study evaluated trends and outcomes of gestational carrier (GC) pregnancies in the U.S. using data from over 14 million deliveries between 2017 and 2020, finding that the prevalence of GC pregnancies rose by 55% during this period.
  • - Among GCs, there was a higher likelihood of complications such as multiple pregnancies, placental abruption, and low-lying placenta, along with increased risks for late-preterm deliveries and postpartum hemorrhage in singleton births compared to non-GCs.
  • - While GC pregnancies are relatively rare, the findings indicate they are becoming more common and generally have favorable pre-pregnancy characteristics, but their obstetric outcomes can be mixed, especially regarding certain complications. *
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Introduction: Considering the effective treatment of postpartum hemorrhage, intrauterine balloon tamponed can apply pressure from the inside of the uterus, and uterine compression suture can apply pressure from the outside of the uterus. Although combining the two methods can enhance the effectiveness of hemostasis, there is a paucity of studies reporting on outcome. The aim of this study was to report a surgical protocol for postpartum hemorrhage by intrauterine balloon tamponing combined with mid-section loop ligation and its subsequent effects on the uterus.

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Objective:  This study aimed to compare the composite maternal hemorrhagic outcomes (CMHOs) among term (≥37 weeks) singletons who had scheduled versus unscheduled cesarean deliveries (CDs). A subgroup analysis was done for those without prior uterine surgeries.

Study Design:  Retrospectively, we identified all singletons at term who had CDs.

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Evidence-based Cesarean Delivery: Postoperative Care (Part 10).

Am J Obstet Gynecol MFM

November 2024

Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Thomas Jefferson University, Philadelphia, PA. Electronic address:

The following review focuses on routine postoperative care after cesarean delivery (CD), including specific Enhanced Recovery After Cesarean (ERAS) recommendations as well as important postpartum counseling points. Following CD, there is insufficient evidence to support administration of prophylactic multi-dose antibiotics to all patients. Additional antibiotic doses are indicated for the following scenarios: patients with obesity, CD lasting ≥ 4 hours since prophylactic dose, blood loss >1,500 mL, or those with an intra-amniotic infection.

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Article Synopsis
  • Rapid correction of chronic hyponatremia can lead to osmotic demyelination syndrome (ODS), especially in patients with underlying conditions like Sheehan’s syndrome, a rare pituitary disorder following severe postpartum hemorrhage.
  • A case report details a 40-year-old woman who experienced neurological decline due to the correction of her long-standing hyponatremia, which had been mismanaged for years, leading to extrapontine and then central pontine myelinolysis.
  • The case emphasizes that even gradual correction of low sodium levels poses risks and highlights the need for careful management in patients with chronic hyponatremia and related conditions.
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Frequency of adverse perinatal outcomes in patients with pregnancy related acute renal (kidney) injury in a tertiary care hospital.

Pak J Med Sci

November 2024

Nazia Liaqat, MBBS, FCPS (Obstetrics & Gynecology) Associate Professor, Department of Gynecology, Medical Teaching Institute, Lady Reading Hospital, Peshawar, Pakistan.

Article Synopsis
  • Pregnancy-related acute kidney injury (Pr-AKI) can lead to serious complications such as stillbirths and neonatal deaths, highlighting the need to understand its impacts on maternal health.
  • A study of 100 women with Pr-AKI revealed that 48% experienced stillbirths, and there was a significant link between these adverse outcomes and ongoing renal issues after delivery.
  • The research suggests that adverse perinatal outcomes, particularly stillbirths, could serve as important predictors for long-term kidney problems in mothers experiencing Pr-AKI.
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Hemophagocytic lymphohistiocytosis in pregnancy-a case report.

Obstet Med

April 2024

Department of Obstetrics and Gynaecology, Latifa Hospital, Dubai Academic Health Corporation, Dubai, United Arab Emirates.

Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening condition that is a rare occurrence in pregnancy and can be elusive in its diagnosis thereby delaying treatment. We report the case of a 30-year-old female patient at 36 weeks of pregnancy who presented with a persistent fever that did not respond to antibiotics. After we investigated her thoroughly, considering the persistent fever, we performed a bone marrow biopsy as part of the workup for prolonged pyrexia.

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A case of hyponatraemia cured by delivery.

Obstet Med

April 2024

Obstetric Medicine, Mater Health, Raymond Terrace, South Brisbane, Australia.

Article Synopsis
  • * It occurs in about 0.27% of pregnant women, usually caused by conditions like hyperemesis gravidarum early on and preeclampsia later in the pregnancy.
  • * Factors like prolonged labor, cesarean sections, and excessive water intake can worsen hyponatraemia by increasing antidiuretic hormone levels, but cases can resolve quickly after childbirth.
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