The role of blood donation on wheels in the blood collection chain operational logistics during the first wave of coronavirus disease 2019 pandemic.

Background And Objectives: The blood collection agencies (BCAs) employ two major logistical modes of conduct for outdoor blood collection. First, the collection agency walks to the donor's preferred location for routine blood donation drives. Second, the drive is conducted using a heavy-duty vehicle having all the facilities for blood donation in it - Blood Donation on Wheels - hereinafter referred to as mobile blood drive (MBD).

Transfusion efficacy of leucoreduced packed red blood cells prepared by two different methods: A randomized controlled trial in transfusion-dependent thalassaemia patients (FUEL trial).

Background And Objectives: Great variations may be observed in the haemoglobin (Hb) content of packed red blood cell (PRBC) units prepared by different methods. This study aimed to assess the Hb increment in thalassaemia major patients transfused with leucoreduced PRBCs (LPRBCs) prepared by two different methods: (i) standard leucoreduced PRBCs (SLPRBCs) and (ii) leucoreduced PRBCs prepared by a new method where leucoreduction of whole blood is done first (NLPRBCs).

Materials And Methods: This prospective, randomized, controlled trial included 80 adult thalassaemia major patients who were randomized into two groups of 40 each.

Burden of rheumatic diseases among people with diabetes: A systematic review and meta-analysis.

Diabetes mellitus type 2 (DM2) is a prevalent metabolic condition affecting over 500 million people globally and associated with serious comorbidities, including various rheumatologic conditions. Some studies have reported a significant association between rheumatological conditions and DM2. However, the global burden of rheumatological conditions among people with DM2 remains unknown.

Predictors and Outcomes of Extubation Failure in Preterm Neonates: A Systematic Review.

Context: Extubation failure (EF) is common in preterm neonates and may be associated with adverse outcomes.

Objective: To systematically review and meta-analyze the existing literature on predictors and outcomes of EF in preterm neonates.

Data Sources: MEDLINE, Epub Ahead of Print, In-Process & Other Non-Indexed Citations, Embase (OvidSP), CINAHL (EBSCOHost), and Cochrane Library (Wiley) from 1995 onward.

Tissue fibrosis in cardiorenal syndrome: crosstalk between heart and kidneys.

Cardiorenal syndrome (CRS) is represented as an intricate dysfunctional interplay between the heart and kidneys, marked by cardiorenal inflammation and fibrosis. Unlike other organs, the repair process in cardiorenal injury involves a regenerative phase characterized by proliferation and polyploidization, followed by a subsequent pathogenic phase of fibrosis. In CRS, acute or chronic cardiorenal injury leads to hyperactive inflammation and fibrotic remodeling, associated with injury-mediated immune cell (Macrophages, Monocytes, and T-cells) infiltration and myofibroblast activation.

How to Design a Study and Write a Grant in Radiology?

Radiology as a specialty has grown immensely over the last few decades. The advancements in diagnostic radiology are facilitated by state-of-the-art equipment and a revolution in computation. Parallelly, interventional radiology has benefited and interventional radiologists are at the forefront of several therapeutic procedures.

Ethics: The Elixir of Publications.

Scientific papers are the driving force for research, information dissemination, and policymaking that directly impacts society. Thus, ethical practices are the elixir of publications. Adherence to ethical practices promotes integrity in research and publication.

Building Credibility with Comprehensive Citation Practices.

Honoring those who paved the way and paving the way for others is an old saying and practice that emphasizes the importance of acknowledging the contributions of others while also guiding and mentoring those who follow in your footsteps. In academic and scientific writings, citations are very important for maintaining the integrity, credibility, and progression of scientific knowledge. This article examines the significance of citations, their various types and methods, and the different styles used.

Historiography of Scientific Publishing across Cultures and Disciplines.

Historiography is a vital perspective of our scientific literature that charts the evolution of scientific publishing, from its early origins to the present status. The key transformations including the shift from a limited self-published legacy to specialized and professional peer-reviewed journals, the impact of technological advancements, and the emergence of new profitable business models are learning points for the future course and couture. Science is pursued and persevered by real humans in social and cultural contexts and not in isolation of laboratories or clinics.

Transitioning from Teaching to Mentoring in Medical Sciences.

The transition from traditional teaching to mentoring in medical education is urgently required to create future-ready physicians, researchers, and medical teachers in India. A roadmap was drawn by the pioneers of modern medicine more than 100 years ago, who mentored and prepared the next generation of subspecialists and teachers. We need mentors rather than conventional teachers to inspire students to dream, learn, and grow.

Navigating the Editorial Gauntlet for Excellence in Radiology Publishing.

Any scientific journal of repute constantly strives to ensure the highest possible quality, integrity, and ethical standards of published research. This article attempts to the highlight multifaceted responsibilities of an Editor in Chief (EiC) and editors such as managing the peer review process, detecting plagiarism, and ensuring quality of selected manuscript before publication. The EiC also has to tackle issues of salami slicing, duplicate submissions, secondary publications, and guest and ghost authorship while adhering to constantly evolving guidelines of the International Committee of Medical Journal Editors (ICMJE) and the Committee on Publication Ethics (COPE).

Clinical features and outcomes of total pancreatic lipomatosis with chronic pancreatitis: a case series.

Background: Fatty changes in the pancreas are common, whereas total pancreatic lipomatosis (PL) is rare. Commonly associated with various components of metabolic syndrome and metabolic-associated steatotic liver disease, total PL can have various etiologies and can manifest with severe pancreatic exocrine insufficiency.

Method: We retrospectively analysed the clinical profile and management outcomes of 8 patients (mean age: 37.

Prevention of Delirium in the Intensive Care Unit through Nonpharmacological Interventions: An Umbrella Review.

Introduction: Delirium is a syndrome commonly seen in intensive care unit (ICU) patients. It is characterized by acute changes in mental status, inattention, disorganized thinking, and altered level of consciousness. Due to its higher prevalence in mechanically ventilated ICU patients, it is crucial to recognize it early and implement standardized evidence-based protocols for preventing it in regular practice.

Successful Treatment of Chronic Wound in a Patient with Longstanding Shell Injury on Heel using, a Novel Product Formulation: A Case Report.

Introduction: Chronic wounds pose a significant burden on patients' physical and mental well-being and significantly raise health-care costs.

Case Report: We report healing with VG111 application alone in a case of chronic wound in a patient who sustained a shell injury to the heel 35 years prior in 1988. Despite conventional wound care and multiple surgeries, the wound persisted.

Burden of diabetes in correctional facilities: A global systematic review and meta-analysis.

Background: Diabetes mellitus presents significant public health challenges worldwide. While its prevalence and management in the general population have been extensively studied, comprehensive research on diabetes among incarcerated individuals is lacking. This study aims to conduct a systematic review and -analysis to determine the prevalence of diabetes within the prison population.

Up-front dissection of the uterovesical space or "bladder-first approach" reduces hemorrhage and bladder injury during hysterectomy for placenta accreta spectrum: reconfirmed in 78 more cases in a prospective single-center study.

Background: Cesarean hysterectomy for placenta accreta spectrum disorder may be associated with severe hemorrhage because of placental invasion of the myometrium and the uterovesical space or parametrium. It leads to serious complications, such as massive hemorrhage requiring massive transfusion, coagulopathy, bladder and ureteric injuries, need for intensive care unit admission and prolonged hospital stay. To reduce the complications of cesarean hysterectomy for placenta accreta spectrum disorder, ongoing efforts are being made to develop different surgical approaches.

Association of C4 Null Alleles and Persistently Low C4 in Asian Indian Patients With Systemic Lupus Erythematosus.

The association between heterozygous C4 deficiency and systemic lupus erythematosus (SLE) is unclear. There is a lack of data in South Asian Indians on any possible association of C4A and C4B null alleles with lupus. We aimed to study the prevalence of C4A and C4B null alleles in a cohort of SLE patients with persistently low C4 levels compared to healthy controls (HC).

Effect of isotonic sodium bicarbonate infusion on perioperative acid-base status among patients undergoing emergency laparotomy for perforation peritonitis (ISABEL trial): a randomized controlled trial.

Purpose: Perioperative metabolic acidosis negatively affects patient outcomes. Perioperative fluid therapy has a clinically significant effect on acid-base balance. This study was conducted to evaluate the effects of isotonic sodium bicarbonate infusion (ISB) versus balanced crystalloid solution (BCS) on perioperative acid-base balance, in terms of postoperative base excess, among patients undergoing emergency laparotomy for perforation peritonitis.