169 results match your criteria: "Postgraduate Institute of Medical Education and Research. Chandigarh[Affiliation]"

Article Synopsis
  • Silibinin, a flavonoid from milk thistle, shows anti-cancer properties by inducing cell death in human colon cancer HT-29 cells.
  • In experiments, treating the cells with increasing concentrations of silibinin for up to 72 hours led to a significant decrease in cell viability, peaking at a 78% reduction.
  • The study confirmed that silibinin's effectiveness in killing cancer cells increases over time, supporting its potential as an anticancer agent in line with previous research findings.
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Context: The foreign ingestion is common occurrence but migration to pancreas is rare entity. Most of foreign bodies pass spontaneously through the anus but about 1% can perforate the wall of stomach or duodenum to reach solid organ. Pancreatic foreign body can results in fatal complication.

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Introduction: Archival tissue samples preserved in formalin are a great source of treasure for biomedical research and diagnostics. Formalin, though is a good preservative, causes the modification of nucleic acid limiting the application of fixed tissues. The present study evaluated three methods of RNA extraction for constitutive gene expression and pathogen detection.

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Retinal ischemia is a major cause of blindness worldwide. It is associated with various disorders such as diabetic retinopathy, glaucoma, optic neuropathies, stroke, and other retinopathies. Retinal ischemia is a clinical condition that occurs due to lack of appropriate supply of blood to the retina.

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Context: Anomalous junction of pancreaticobiliary ducts is a condition in which the pancreatic duct and the bile duct join outside the duodenal wall with a long common channel. The most accepted classification of various types of anomalous pancreaticobiliary junction is the new Komi classification. The majority of cases of type III anomalous pancreaticobiliary junction are reported from Japan and very seldom from outside Japan.

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Folates are members of the B-class of vitamins, which are required for the synthesis of purines and pyrimidines, and for the methylation of essential biological substances, including phospholipids, DNA, and neurotransmitters. Folates cannot be synthesized de novo by mammals; hence, an efficient intestinal absorption process is required. Intestinal folate transport is carrier-mediated, pH-dependent and electroneutral, with similar affinity for oxidized and reduced folic acid derivatives.

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Objective: To determine the utility of tissue harmonic imaging in evaluating cystic renal lesions and to compare these findings with conventional ultrasound guidance (USG) and CT.

Methods: Thirty patients, detected with cystic renal lesions on routine USG (over a period of 18 months from July 2004 to December 2005 at the Postgraduate Institute of Medical Education and Research Chandigarh, Chandigarh, India) were included in this study. All patients underwent a conventional gray scale ultrasound study (GSI), followed by tissue harmonic imaging (THI) sonography on the same machine (advance technology limited high definition imaging 5000).

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Background: Oromaxillofacial surgical procedures present a unique set of problems both for the surgeon and for the anesthesist. Achieving dental occlusion is one of the fundamental aims of most oromaxillofacial procedures. Oral intubation precludes this surgical prerequisite of checking dental occlusion.

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Aim: To study the etiological profile of short stature at a tertiary care hospital in north India.

Methods: In this prospective study, 176 children with short stature were enrolled from January 2005 to December 2006. Appropriate screening and definitive tests were performed to establish the etiology of short stature.

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Context: Spleen-preserving distal pancreatectomy is a well-accepted procedure for benign tumors of the distal pancreas. Its safety and feasibility have been proven. However many doctors have not used this procedure due to the trauma involved.

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Therapeutic potentials of bovine colostrums.

Indian J Pediatr

October 2005

Division of Pediatric Gastroenterology, Postgraduate Institute of Medical Education and Research Chandigarh, India.

Colostrum is the first milk produced by mammals for their young ones. This transfers the passive immunity gained by the mother to the baby. The bovine colostrum (BC) can be obtained in large quantity and has properties similar to human colostrum.

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With increasing acceptance of living organ transplantation and growing numbers of organ donors, it becomes important to look for any adverse outcomes in this population. Prospective psychosocial evaluation of living related donors and assessment of the outcome of donation process was done. We also tried to identify any risk factors associated with any adverse event.

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Objective: To study bronchial hyperresponsiveness (BHR) in patients with sarcoidosis.

Methods: Twenty freshly diagnosed patients with sarcoidosis were evaluated. Progressively increasing concentrations of methacholine were administered using a standard five-breath dosimeter protocol, and spirometry performed after each challenge.

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Bilateral choanal atresia is potentially life-threatening. The condition almost always presents in the new born, with alternating phases of respiratory distress and apnoea relieved by crying. We report a rare case of bilateral choanal atresia presenting for the first time at 22 years of age.

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Bronchial carcinoids usually present with pulmonary symptoms. Neurohumoral manifestations in the form of acromegaly and Cushing's syndrome are rarely encountered. We report a case of bronchial carcinoid with features of acromegaly due to ectopic production of growth hormone-releasing hormone.

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An 84-year-old man was diagnosed with esophageal perforation following ingestion of a blister-wrapped tablet. His condition improved after 2 weeks of conservative treatment using antibiotics and high-protein enteral nutrition.

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Weights and measurements of paired kidneys obtained from medicolegal autopsies of northwest Indian adults, 155 males and 84 females, were compared. The right and left kidneys weighed 108.7 +/- 22.

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