154 results match your criteria: "Post Head Injury Endocrine Complications"

Article Synopsis
  • Traumatic brain injury (TBI) often leads to endocrine issues, particularly dysfunction of the pituitary axis, with a prevalence of about 33% according to the review of 52 studies and 7367 participants.
  • The study investigated the onset and prevalence of these dysfunctions over time, revealing that rates vary depending on the time since injury: highest in the first 3 months and somewhat consistent beyond one year.
  • Specific hormone deficiencies identified included Growth Hormone (18%), adrenocorticotropic hormone (10%), pituitary-gonadal hormones (16%), and thyroid-stimulating hormone (6%), indicating that ongoing monitoring of these hormone levels is essential for individuals recovering from TBI.
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Background: Recurrent laryngeal nerve (RLN) injury is a known complication of thyroidectomy. Most cases manifest immediately and are promptly recognized. Rarely, some patients experience delayed-onset vocal cord palsy.

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During thyroidectomy, both needle electrodes (NE) and endotracheal tube electrodes (ETE) can be used. Incomplete contact of the endotracheal tube electrode with the vocal cords, endotracheal tube electrode may hinder an optimal outcome and even result in an inability to obtain an electromyography wave while neuromonitoring the external branch of the superior laryngeal nerve (EBSLN). There is no study that compares NE and ETE for EBSLN monitoring.

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Objective: Anterior pituitary dysfunction is one of the major causes of disability and morbidity in patients suffering from traumatic brain injury (TBI). The present study was undertaken to evaluate the incidence of anterior pituitary dysfunction in cases of moderate and severe TBI, its value in long-term prognostication, and the factors that predispose to a higher incidence of anterior pituitary dysfunction in acute and chronic phases.

Methods: This was a prospective cohort study wherein 216 patients with moderate and severe TBI were evaluated within 72 hours of TBI (acute phase) and at 6 months (chronic phase).

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Innate immune memory after brain injury drives inflammatory cardiac dysfunction.

Cell

August 2024

Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany. Electronic address:

Article Synopsis
  • - Chronic comorbidities following a stroke contribute significantly to patient health, and this study investigates how immune system changes may play a role in these issues.
  • - Researchers discovered that the immune response, particularly in monocytes/macrophages, remains persistently pro-inflammatory in various organs, especially the heart, even months after a stroke.
  • - Targeting IL-1β and blocking certain immune cell movement successfully prevented heart dysfunction in a study, suggesting potential new therapies for managing post-stroke complications.
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Objective: This study aimed to investigate the limitations, barriers, and complications in the early transition from the microscopic transsphenoidal approach (MTA) to the endonasal endoscopic approach (EEA) to the skull base in our institution.

Methods: Technical challenges, as well as clinical features and complications, were compared between MTA, EEA, and mixed cases during the early surgical curve.

Results: The period from the early learning curve was 1 year until the EEA protocol was used routinely.

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Introduction: Thyroidectomy technique and extent are related to parathyroid injury and hypoparathyroidism. Total thyroidectomy is one of the most commonly performed endocrine surgeries, and the majority of patients recover completely without any complications. However, persistent hypoparathyroidism is the most prevalent long-term consequence following total thyroidectomy.

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Introduction: Traumatic brain injury (TBI) can disrupt the hypothalamo-pituitary axis, causing neuroendocrine dysfunction. As a third of children can develop post-traumatic hypothalamo-pituitary axis dysfunction (HPAD), a longitudinal follow-up is required in children with TBI.

Method: The study comprised a pre-quality improvement (QI) phase (baseline phase) and a QI phase (post-intervention phase).

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Objective: To investigate secondary adrenal insufficiency post varying traumatic brain injuries' and its impact on prognosis.

Methods: 120 traumatic brain injury patients were categorized into mild, moderate and severe groups based on Glasgow Coma Scale. Adrenal function was evaluated through testing.

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Thermal injury to recurrent laryngeal nerve (RLN) during radiofrequency ablation (RFA) can produce temporary or permanent vocal cord paralysis. Hydrodissection with cold 5% glucose of "danger triangle" protects RLN during RFA. When RFA is performed under local anesthesia, RLN function is monitored by patients producing vocal sounds.

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Unusual and lesser-known rare causes of adult growth hormone deficiency.

Best Pract Res Clin Endocrinol Metab

December 2023

Department of Endocrinology, PGIMER, Chandigarh, India. Electronic address:

Growth hormone is among the most common hormones to be deficient in pituitary insult. It can occur either in isolation or combined with other hormone deficiencies. Growth hormone deficiency in adults (AGHD) can be due to causes acquired in adulthood or have a childhood-onset etiology, but the former is about three times more common.

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Objective Accidental traumatic brain injury (TBI) can lead to severe complications such as endocrine abnormalities and long-term morbidities and can negatively impact patient lives. These conditions are also associated with a high cost of treatment over a lifetime, a significant concern in low-to-middle-income countries (LMICs). In Pakistan, the prevalence of children with endocrine abnormalities secondary to TBI remains largely unexplored.

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Discrepancies in Thyroidectomy Outcomes Between General Surgeons and Otolaryngologists.

Indian J Otolaryngol Head Neck Surg

December 2022

Division of Trauma, Burns and Surgical Critical Care, Department of Surgery, Irvine Medical Center, University of California, 333 The City Blvd West, Suite 1600, Orange, CA 92868 USA.

Article Synopsis
  • Thyroidectomy, a common surgery to remove the thyroid gland, is performed by both general surgeons and otolaryngologists, but few studies compare their complication rates.
  • A study analyzed data from over 11,000 thyroidectomy patients to evaluate postoperative complications like RLN injury and hypocalcemia, finding that surgeries performed by general surgeons had a higher risk of these complications.
  • Factors like surgical technique, experience, and use of specific tools (e.g., energy devices vs. RLN monitoring) may explain the differences in complication rates between the two specialties, highlighting the need for continued research in this area.
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Objective: Childhood hydrocephalus patients treated by ventriculo-peritoneal (v.-p.) shunting are sometimes referred years after this therapy for evaluation of suspicious pituitary enlargement.

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Hypopituitarism, which refers to insufficiency of one or more hormones of the pituitary, can be due to myriad causes. The clinical and radiological spectrum of the condition is heterogeneous, based on the patient's age, gender, clinical setting, and/or other past medical history. Hypopituitarism includes central hypocortisolism, hypothyroidism, hypogonadism, and growth hormone deficiency.

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Alcohol consumption affects the late endocrine consequences of mild traumatic brain injury.

Neuro Endocrinol Lett

November 2022

Division of Endocrinology, Department of Internal Medicine, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.

Background: Currently there are no widely applied methods which could identify, at the time of head trauma, those mild traumatic brain injury (mTBI) patients who later develop pituitary dysfunction. The effect of alcohol consumption on post-TBI endocrine dysfunction is unclear.

Methods: Five hundred and eight TBI patients, 406 of them with mTBI, were studied.

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Clinical application of endoscopic surgery using a gasless unilateral transaxillary approach in the treatment of primary hyperparathyroidism.

Front Surg

September 2022

Otolaryngology / Head and Neck Center, Cancer Center, Department of Head and Neck Surgery, Zhejiang Provincial People's Hospital (Affliated People's Hospital, Hangzhou Medical College), Hangzhou, China.

Objectives: To investigate the safety and feasibility of gasless axillary parathyroid surgery in the treatment of primary hyperparathyroidism.

Methods: A total of 12 patients who received gasless axillary parathyroidectomy (endoscope group) and 14 patients who received traditional open parathyroidectomy (open group) from January 2019 to April 2022 were screened and included. The differences in baseline characteristics, surgical efficiency, incidence rate of complications, changes in biochemical indicators, and incision satisfaction between the two groups were analyzed and compared.

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Increasing rates of sport-related concussion (SRC) in youth impose a significant burden on public health systems and the lives of young athletes. Accurate prediction for those likely to develop persistent post-concussion symptomology (PPCS) using a fluid biomarker, reflecting both acute injury and recovery processes, would provide the opportunity for early intervention. Cortisol, a stress hormone released through the hypothalamic-pituitary-adrenal (HPA) axis following injury, may provide a missing physiological link to clinical recovery.

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The field of endocrine surgery has expanded from the traditional open neck approach to include remote access techniques as well as minimally invasive approaches for benign and malignant thyroid nodules. In experienced hands and with careful patient selection, each approach is considered safe, however complications can and do exist. Post-operative dysphonia can have serious consequences to the patient by affecting quality of life and ability to function at work and in daily life.

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Importance: Increased risk of neurological and psychiatric conditions after traumatic brain injury (TBI) is well-defined. However, cardiovascular and endocrine comorbidity risk after TBI in individuals without these comorbidities and associations with post-TBI mortality have received little attention.

Objective: To assess the incidence of cardiovascular, endocrine, neurological, and psychiatric comorbidities in patients with mild TBI (mTBI) or moderate to severe TBI (msTBI) and analyze associations between post-TBI comorbidities and mortality.

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Diagnosis and surgical repair of delayed tracheal perforation post thyroidectomy in context of previous cranio-spinal radiotherapy - A case report.

Int J Surg Case Rep

February 2022

General and Endocrine Surgery, Department of General Surgery, Rockingham General Hospital, Elanora Drive, Cooloongup, Western Australia 6168, Australia. Electronic address:

Introduction And Importance: This is the first case of delayed tracheal perforation post total thyroidectomy in the context of previous radiotherapy to the neck. Such a presentation can be easily misdiagnosed and managed as a seroma at significant risk to the patient, as the latter had no precipitating factors and cardiorespiratory compromise. There are nineteen previously described cases of delayed tracheal injury post thyroidectomy of variable severity and variable intervention.

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Routine Exposure Versus Non-Exposure of Recurrent Laryngeal Nerve during Thyroid Surgery: Our Experience of 300 Cases.

Mymensingh Med J

January 2022

Dr Sudhangshu Shekhar Biswas, Associate Professor, ENT and Head Neck Surgery Department, BIRDEM General Hospital & Ibrahim Medical College (IMC), Dhaka, Bangladesh; E-mail:

The technique of thyroidectomy has been in evolution for many years. It is a basic rule of surgery that an important structure of a human body must be recognized certainly during the surgical procedure in order to prevent its damage. The purpose of this study was to evaluate our routine identification and without identification of recurrent laryngeal nerve during thyroidectomy aiming to lessen the inadvertent injury of the recurrent laryngeal nerve.

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Effect of surgeon volume on pediatric thyroid surgery outcomes: A systematic review.

J Pediatr Surg

September 2022

Division of Pediatric Surgery, Department of Surgery, Northwestern University Feinberg School of Medicine, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, United States. Electronic address:

Background: Pediatric thyroidectomy has been identified as a surgical procedure that may benefit from concentrating cases to high-volume surgeons. This systematic review aimed to address the definition of "high-volume surgeon" for pediatric thyroidectomy and to examine the relationship between surgeon volume and outcomes.

Methods: PubMed, Embase, Cochrane Library, Scopus, Web of Science, ClinicalTrials.

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Improving Voice Outcomes After Thyroid Surgery - Review of Safety Parameters for Using Energy-Based Devices Near the Recurrent Laryngeal Nerve.

Front Endocrinol (Lausanne)

February 2022

Department of Otorhinolaryngology-Head and Neck Surgery, International Thyroid Surgery Center, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.

Technological advances in thyroid surgery have rapidly increased in recent decades. Specifically, recently developed energy-based devices (EBDs) enable simultaneous dissection and sealing tissue. EBDs have many advantages in thyroid surgery, such as reduced blood loss, lower rate of post-operative hypocalcemia, and shorter operation time.

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One hundred and one consecutive transoral endoscopic parathyroidectomies via the vestibular approach for PHPTH: a worldwide multi-institutional experience.

Surg Endosc

July 2022

Division of Head and Neck Endocrine Surgery, Department of Otolaryngology Head and Neck Surgery, Johns Hopkins University, 601 N. Caroline 6th Floor, Baltimore, MD, 21287, USA.

Article Synopsis
  • The transoral vestibular approach for parathyroid surgery is gaining popularity for treating primary hyperparathyroidism (PHPTH) and may offer a scarless option for patients.
  • A study involving 101 patients assessed the safety and effectiveness of this technique, showing a high surgical success rate of 98% in achieving normal parathyroid hormone (PTH) levels post-operation.
  • Results indicated minimal complications, with no permanent nerve injuries and a significant decrease in surgical time from the first half to the second half of the cases.
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