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173,522 results match your criteria: "Portugal; National Institute of Health[Affiliation]"
Foods
February 2025
Higher School of Biological Sciences of Oran, BP 1042 Saim Mohamed, Cité Emir Abdelkader (EX-INESSMO), Oran 31000, Algeria.
The increasing consumer demand for natural and sustainable food preservation methods has highlighted the potential of lactic acid bacteria (LAB) and their bioactive metabolites, particularly bacteriocins, as effective antimicrobial agents. This study aimed to isolate and characterize strains from Algerian traditional dried figs marinated in olive oil, a nutrient-dense and underexplored food matrix. Twelve isolates were identified as using MALDI-TOF MS and 16S rRNA gene sequencing, ensuring precise taxonomic classification.
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February 2025
Centro de Investigação de Montanha (CIMO), Instituto Politécnico de Bragança, Campus de Santa Apolónia, 5300-252 Bragança, Portugal.
Elderberries, known for their antioxidant, anti-inflammatory, and antiviral properties, have traditionally been used to prevent and treat infections and boost the immune system. By increasing the quantity and quality of certain compounds, fermentation can potentially make them more effective as food additives. The aim of this study was to evaluate the effect of incorporating fermented elderberries on the bioactivity and shelf life of a traditional bread.
View Article and Find Full Text PDFMaterials (Basel)
March 2025
Institute of Ceramic and Glass (ICV-CSIC), c/ Kelsen 5, Campus de Cantoblanco, 28049 Madrid, Spain.
The refractive index is an important parameter for the restoration of historical cultural heritage and for non-destructive optical techniques. In this study, different mathematical models for lead glasses were assessed in order to analyze their feasibility to calculate the theoretical refractive index of the historical enamels in stained-glass windows. The models selected were those specifically developed for lead glasses: the Appen method (1949), the Fanderlik and Skrivan model (1972), and the Bonetti and Salvagno method (1983).
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February 2025
Centro de Química-Vila Real, CQ-VR, Chemistry Department, Escola de Ciências da Vida e do Ambiente (ECVA), University of Trás-os-Montes e Alto Douro, 5001-801 Vila Real, Portugal.
This work explores the deposition of hexagonal (-) LuMnO thin films in the phase and investigates the conditions under which the synergy of ferroelectric and photoactive properties, can be achieved to confirm the potential of this material for applications in the development of next-generation photovoltaic devices. Single-phase -LuMnO was successfully deposited on different substrates, and the thermal stability of the material was confirmed by Micro-Raman spectroscopy analysis from 77 to 850 K, revealing the suitable ferro- to para-electric transition near 760 K. Optical measurements confirm the relatively narrow band gap at 1.
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February 2025
TEMA-Centre for Mechanical Technology and Automation, Department of Mechanical Engineering, University of Aveiro, 3810-193 Aveiro, Portugal.
In the current study, the integration of finite element simulation and machine learning is used to find the optimal combination of processing parameters in the directed energy deposition of SS316L. To achieve this, the FE simulation was validated against previously implemented research, and a series of simulations were conducted. Three inputs, namely laser power, scanning speed, and laser beam radius, and two outputs, namely residual stress and displacement, were considered.
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February 2025
Instituto de Plasmas e Fusão Nuclear (IPFN), Departamento de Engenharia e Ciências Nucleares (DECN), Instituto Superior Técnico, Universidade de Lisboa, Campus Tecnológico e Nuclear, Estrada Nacional 10, 2695-066 Bobadela, Portugal.
Nuclear fusion is a promising energy source. The International Thermonuclear Experimental Reactor aims to study the feasibility of tokamak-type reactors and test technologies and materials for commercial use. One major challenge is developing materials for the reactor's divertor, which supports high thermal flux.
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February 2025
Department of Endodontics, Rey Juan Carlos University, 28032 Madrid, Spain.
This study aimed to analyze the effect of 1% sodium hypochlorite (NaOCl) solution at different temperatures on endodontic file resistance to cyclic fatigue. A total of 90 files, Reciproc NiTi M-Wire (REC) (n = 30), WaveOne Gold (WOG) (n = 30), and Reciproc Blue (RB) (n = 30) were activated under constant irrigation with 1% NaOCl at 5, 37, and 60 °C in a stainless-steel artificial canal (curvature angle = 60°; radius = 5 mm). The time to the fracture and the maximum and minimum load were recorded for each instrument, and data were subjected to statistical analysis.
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February 2025
TEMA-Centre for Mechanical Technology and Automation, Department of Mechanical Engineering, University of Aveiro (UA), Campus Universitário de Santiago, 3810-193 Aveiro, Portugal.
The ongoing pursuit of enhanced efficiency and sustainability in power transformer cooling systems has spurred extensive research into the properties and performance of insulating fluids. This review explores the evolution of transformer cooling technologies, focusing on traditional mineral oils and the emerging roles of alternative fluids, such as natural and synthetic esters, and nanofluids. Mineral oils, though widely used, degrade over time, leading to a reduction in breakdown voltage (BDV) from 46 kV to 30 kV, exhibiting low fire resistance.
View Article and Find Full Text PDFHealthcare (Basel)
March 2025
Comprehensive Health Research Center, 1150-082 Lisboa, Portugal.
Background/objectives: Anxiety and depression result in a greater health burden; both can impact functionality and quality of life. This review aims to understand the association between anxiety, depression, functionality, and quality of life. Although three systematic reviews exist, one focuses on quality of life in depression and anxiety, while the others address functionality in depression and anxiety, with the former being more recent and the latter two being older.
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March 2025
RoboCorp, I2A, Polytechnic Institute of Coimbra, 3045-093 Coimbra, Portugal.
Background: Over the season, competitive swimmers experience a progressive imbalance in rotator cuff strength, predisposing them to a significant risk factor for a swimmer's shoulder injury.
Objectives: Verify the effectiveness of two 12-week preventive programs on the shoulder rotators' peak torque and conventional/functional ratios.
Design: A care provider- and participant-blinded, parallel, randomized controlled trial with three groups.
Healthcare (Basel)
February 2025
Nursing Department of Higher School of Health, University of Trás-os-Montes and Alto Douro, 5000-801 Vila Real, Portugal.
This study aims to analyze the correlation between healthcare professionals' knowledge of hand hygiene protocols and their actual adherence to these practices. Specifically, we investigate whether higher knowledge levels correspond to better compliance, and we examine potential influencing factors such as professional role, gender, and prior training in infection control. A non-probabilistic, convenience sample was composed of 51 healthcare professionals working in patient care.
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February 2025
Population Health Research Institute, St George's, University of London, London SW17 ORE, UK.
Background: Stroke is a leading cause of death and disability, underscoring the importance of effective self-management programs to improve the quality of life for survivors.
Objectives: This study investigates the impact of the ComVida (Bridges-PT) self-management program on self-efficacy, physical function, health-related quality of life, and emotional state of stroke survivors in Portugal.
Methods: A quasi-experimental study was conducted with 28 participants from hospital and community settings.
Healthcare (Basel)
February 2025
Department of Psychology and Education, Portucalense University, 4200-072 Porto, Portugal.
: Cancer diagnosis and oncological treatments often lead to cognitive impairments, particularly in prospective memory, which affects the ability to recall future intentions. These difficulties can significantly impact therapeutic adherence, especially in the early stages of treatment, where timely medication and appointment adherence are critical. Despite this, effective measures for assessing prospective memory in cancer survivors remain limited.
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February 2025
Research Centre for Anthropology and Health, University of Coimbra, 3000-456 Coimbra, Portugal.
: Research considering objectively measured moderate-to-vigorous physical activity (MVPA) and sedentary behaviors (SB) and health outcomes among urban children has produced equivocal findings. Therefore, this study was designed (i) to compare MVPA and SB of urban and non-urban children and (ii) to analyze associations between the risk of overweight and MVPA of children by their degree of urbanization. : The sample comprised 389 children (195 girls) aged 6 to 10 years.
View Article and Find Full Text PDFInt J Mol Sci
February 2025
Centro de Investigação Interdisciplinar Egas Moniz, Cooperativa de Ensino Egas Moniz, 2825-084 Caparica, Portugal.
The misuse of opioids and opiates has remained a persistent issue since the 19th century. The recent resurgence of non-fentanyl synthetic opioids, such as U-type opioids and nitazenes, has further exacerbated the ongoing crisis. Identifying these synthetic opioids presents many challenges, including the emergence of new substances, the lack of standards, and the presence of structural isomers.
View Article and Find Full Text PDFInt J Mol Sci
February 2025
Polytechnic University of Coimbra, Rua da Misericórdia, Lagar dos Cortiços, S. Martinho do Bispo, 3045-093 Coimbra, Portugal.
The present paper addresses topics from various fields of biology. Its purpose is to enlarge the understanding of the usage of bioinformatics tools in the phylogenetic analysis of RNA viruses. The paper highlights the benefits of using information technology in virology, bringing the scientific community closer to unraveling the mysteries of RNA virus evolution and their adaptation to different niches and hosts and facilitating the understanding of their rapid mutation processes.
View Article and Find Full Text PDFInt J Mol Sci
February 2025
CIQUP-IMS, Department of Chemistry and Biochemistry, Faculty of Sciences, University of Porto, R.Campo Alegre s/n, 4169-007 Porto, Portugal.
Edaravone is one of the treatment options for Amyotrophic Lateral Sclerosis, but its therapeutic efficacy is limited due to the incapacity to cross the blood-brain barrier, as well as its short life span and poor stability, which is ultimately caused by its tautomerism in physiological condions. This work presents an overview about the use of several nanoformulations based on polymeric, protein, lipidic, or hybrid structure as suitable and stable drug delivery systems for encapsulating edaravone. We also evaluated the functionalization of nanoparticles with pegylated chains using the polyethylene glycol or tocopherol polyethylene glycol succinate and the possibility of preparing polymeric nanoparticles at different pH (7.
View Article and Find Full Text PDFInt J Mol Sci
February 2025
Centre of Marine Sciences, University of Algarve, 8005-139 Faro, Portugal.
Zinc finger protein 687 (ZNF687), a transcription factor implicated in osteoblast/osteoclast differentiation and linked to Paget's disease of bone, has unclear mechanisms in bone metabolism. Epigenetic disruptions can affect bone cell activity and contribute to bone-related diseases. This work aimed to elucidate the regulatory role of epigenetics in modulating expression throughout osteoblast differentiation and bone growth/aging in mice.
View Article and Find Full Text PDFInt J Mol Sci
February 2025
i3S-Instituto de Investigação e Inovação em Saúde, Universidade do Porto, 4200-135 Porto, Portugal.
The introduction of CFTR modulators in the clinics has improved body mass index in cystic fibrosis (CF) individuals. Leptin is a major regulator of appetite and energy expenditure but is also involved in bone metabolism. Whether circulating leptin levels are associated with low bone mineral density (BMD) and fracture risk in CF remains unknown.
View Article and Find Full Text PDFInt J Mol Sci
February 2025
CNC-UC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.
Diabetic foot ulcers (DFUs) are a devastating complication of diabetes, presenting limited treatment success rates due to their complex pathophysiology. Bone morphogenetic protein 7 (BMP7) confers tissue protective and regenerative functions, but its potential role in diabetic wound healing is unknown. The aim of this study was to investigate the effects of topical BMP7 treatment in wound healing using a streptozotocin-induced diabetic mouse model.
View Article and Find Full Text PDFInt J Mol Sci
February 2025
Centre for the Research and Technology of Agro-Environmental and Biological Sciences (CITAB), University of Trás-os-Montes e Alto Douro (UTAD), 5000-801 Vila Real, Portugal.
Soil salinity is one of the most severe impacts of climate change, negatively affecting plant growth and development. Seed germination and seedling emergence are among the most critical stages susceptible to salt stress, making it important to explore them to identify the most resilient accessions for crop yield improvement. Cowpea ( L.
View Article and Find Full Text PDFMolecules
March 2025
Research Centre for Active Living and Wellbeing (LiveWell), Instituto Politécnico de Bragança, Campus de Santa Apolónia, 5300-253 Bragança, Portugal.
Sericin has been characterized as demonstrating a variety of bioactivities, establishing it as a valuable resource for biomedical and pharmaceutical applications. The diverse biological activities of sericin are likely linked to its unique biochemical composition and properties. This study aimed to assess the effect of origin, seasonality, and amino acid composition on the bioactivity of sericin samples from two Portuguese regions compared to commercial sericin.
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February 2025
Instituto de Física Fundamental, Consejo Superior de Investigaciones Científicas, Serrano 113-bis, 28006 Madrid, Spain.
Total electron scattering cross sections (TCSs), in the energy range of 1-100 eV, have been measured with a high-resolution magnetically confined electron transmission apparatus, with total uncertainty limits estimated to be within ±5%. No previous experimental TCS data have been found for comparison. Electron attachment resonances, corresponding to transient negative ion formation, have been identified for energies below 20 eV by analyzing their contribution to the measured local maxima of the TCSs.
View Article and Find Full Text PDFPolymers (Basel)
February 2025
Instituto de Engenharia Mecânica (IDMEC), Instituto Superior Técnico, Av. Rovisco Pais 1, 1049-001 Lisboa, Portugal.
Waste stone sludge generated by the extractive industry has traditionally posed significant disposal challenges. This study redefines stone sludge as a valuable raw material by incorporating it into polylactic acid (PLA) to create sustainable composite materials. Pellets and filaments composed of up to 50% by weight of limestone powder and PLA were successfully produced using melt blending in a twin-screw extruder.
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February 2025
Departamento de Engenharia Mecânica, Faculdade de Engenharia, Universidade do Porto, Rua Dr. Roberto Frias, 4200-465 Porto, Portugal.
In modern engineering applications, the use of sustainable materials and eco-friendly methods has become increasingly important. Wood joints, especially those strengthened with bio-adhesive, have attracted considerable attention due to their inherent environmental benefits and desirable mechanical properties. Compared to traditional joining methods, adhesive joints offer unique advantages such as improved load distribution, reduced stress concentration, and enhanced aesthetic appeal.
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