170,048 results match your criteria: "Portugal; Clinical Academic Center-Braga (2CA-Braga)[Affiliation]"
J Environ Manage
December 2024
CE3c - Centre for Ecology, Evolution and Environmental Changes & CHANGE - Global Change and Sustainability Institute, Departamento de Biologia Animal, Faculdade de Ciências, Universidade de Lisboa, 1749-016, Lisboa, Portugal.
Bats provide important ecosystem services, particularly in agriculture, yet integrating bat management into conservation plans remains challenging. Some landscape features considerably influence bat presence, diversity, and ecosystem service provision. Understanding the relationship between landscape structure, composition, pest suppression, and ecosystem services is crucial.
View Article and Find Full Text PDFDermatol Ther (Heidelb)
December 2024
Inovapotek, Pharmaceutical Research & Development, Porto, Portugal.
Introduction: The human skin acts as a protective barrier against external pathogens and hosts a diverse microbiome consisting of bacteria, fungi, viruses, and archaea. Disruptions to the skin microbiome can impact immune function, leading to inflammatory and autoimmune conditions. The importance of pH for the microbiome is paramount.
View Article and Find Full Text PDFJ Neurosci Methods
December 2024
Sussex AI, University of Sussex, Falmer, Brighton, BN1 9QJ, UK. Electronic address:
Background: Single-sensillum recordings are a valuable tool for sensory research which, by their nature, access extra-cellular signals typically reflecting the combined activity of several co-housed sensory neurons. However, isolating the contribution of an individual neuron through spike-sorting has remained a major challenge due to firing rate-dependent changes in spike shape and the overlap of co-occurring spikes from several neurons. These challenges have so far made it close to impossible to investigate the responses to more complex, mixed odour stimuli.
View Article and Find Full Text PDFRev Esp Anestesiol Reanim (Engl Ed)
December 2024
Department of Anaesthesiology, Hospital Beatriz Ângelo, Loures, Portugal.
Pneumocephalus refers to the presence of air within the intracranial cavity, and albeit its occurrence following neuraxial techniques is rare, it is commonly associated with a loss of resistance to air technique. This case report describes a parturient who underwent neuraxial analgesia for pain management during labour. Epidural space identification with loss of resistance to saline technique was used and she went on to develop a symptomatic pneumocephalus.
View Article and Find Full Text PDFJ Theor Biol
December 2024
Institute of Evolution, Centre for Ecological Research, 1121 Budapest, Hungary; Center for the Conceptual Foundations of Science, Parmenides Foundation, 82343 Pöcking, Germany. Electronic address:
Building on the algorithmic equivalence between finite population replicator dynamics and particle filtering based approximation of Bayesian inference, we design a computational model to demonstrate the emergence of Darwinian evolution over representational units when collectives of units are selected to infer statistics of high-dimensional combinatorial environments. The non-Darwinian starting point is two units undergoing a few cycles of noisy, selection-dependent information transmission, corresponding to a serial (one comparison per cycle), non-cumulative process without heredity. Selection for accurate Bayesian inference at the collective level induces an adaptive path to the emergence of Darwinian evolution within the collectives, capable of maintaining and iteratively improving upon complex combinatorial information.
View Article and Find Full Text PDFInt J Pharm
December 2024
Research Institute for Medicine (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa, Lisbon, Portugal. Electronic address:
Prolonged use of Personal Protective Equipment, like surgical masks, can cause skin issues such as acne ("maskne") and rosacea flare-ups due to pressure and moisture. While dressings can protect the skin, they often reduce mask effectiveness and lack pharmaceuticals to treat common skin lesions. This study introduces an innovative dual-function gelatin/tannic acid-based hydrogel patch incorporating metronidazole (1% w/w) or salicylic acid (2% w/w) to offer both skin protection and treatment.
View Article and Find Full Text PDFAn Sist Sanit Navar
December 2024
Universidad de Vigo. Facultad de Ciencias Empresariales y Turismo. Departamento de Organización de Empresas y Marketing. Vigo. España .
Background: This study aims to assess the impact of transitioning a hospital/foundation from indirect management to direct management on the efficiency of hospital resource management.
Methodology: Until 2010, the Virxe da Xunqueira hospital/foundation, located in the Galicia-North Portugal Euroregion, operated under indirect management. In 2010, it transitioned to direct management as a health centre within the Galician Health Service (Spain).
Res Vet Sci
December 2024
Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, United States of America.
Delayed milk ejection (DME) could compromise udder health and milking performance. The objectives of this systematic review and meta-analysis were to (i) explore the current evidence, assess the risk of bias, and identify the knowledge gaps in published studies that investigated the effect of DME on udder health and milking performance in dairy cows, and (ii) quantify the magnitude of the difference in milk yield per milking session (MY), milking duration (MD), and peak milk flow rate (PFR) between cows with and without DME. We performed the current systematic review and meta-analysis according to PRISMA 2020 statement.
View Article and Find Full Text PDFSci Total Environ
December 2024
Instituto Dom Luiz, Faculdade de Ciências, Universidade de Lisboa, 1749-016 Lisboa, Portugal. Electronic address:
In coastal urban areas highly susceptible to flooding, whether from sea level rise (SLR) or storms, it is crucial to assess the vulnerability and risks posed by extreme and frequent floods. Reliable estimates of extreme natural events' return periods rely on historical data or probabilistic models, requiring extensive and robust data. From climate-scenario-based or semi-empirical models, SLR projections are represented by a central estimate or the full domain cumulative density function (CDF), entailing uncertainties.
View Article and Find Full Text PDFSci Total Environ
December 2024
Centro de Química Estrutural, Institute of Molecular Sciences and Department of Chemical Engineering, Instituto Superior Técnico, Universidade de Lisboa, Av. Rovisco Pais 1, 1049-001 Lisboa, Portugal; Centre d´études nordiques (CEN), Université Laval, Québec, QC G1V 0A6, Canada. Electronic address:
Permafrost predominates in polar and high mountain regions, encompassing nearly 15 % of the exposed land in the Northern Hemisphere. It denotes soil or rock that remains at or below 0 °C for the duration of at least two consecutive years. These frozen soils serve as a barrier to contaminants that are stored and accumulated in permafrost over extended periods of time.
View Article and Find Full Text PDFJ Gerontol A Biol Sci Med Sci
December 2024
Human Nutrition & Exercise Research Centre, Centre for Healthier Lives, Population Health Sciences Institute, Newcastle University, Newcastle Upon Tyne, UK.
Biomarkers of ageing serve as important outcome measures in longevity-promoting interventions. However, there is limited consensus on which specific biomarkers are most appropriate for human intervention studies. This work aimed to address this need by establishing an expert consensus on biomarkers of ageing for use in intervention studies via the Delphi method.
View Article and Find Full Text PDFACS Biomater Sci Eng
December 2024
Department of Pharmacology, Faculty of Pharmacy, Istanbul Kent University, Istanbul 34406, Türkiye.
Epilepsy is one of the oldest neurological disorders discovered by mankind. This condition is firmly coupled with unprovoked seizures stimulated by irrepressible neuroelectrical blasts. Orally taken valproate family has been employed for prophylactic management; however, oral administration is not applicable for critical scenarios, thus calling for medication routes fulfilling necessities of immediate innervation.
View Article and Find Full Text PDFJ Sci Food Agric
December 2024
LAQV-REQUIMTE & Department of Chemistry, Campus Universitário Santiago, University of Aveiro, Aveiro, Portugal.
Background: Purple passion fruit (Passiflora edulis f. edulis) is a highly appreciated fruit typically consumed in fresh or processed into various food products. The peel and seeds, which are by-products of fruit processing, are rich in nutrients and bioactive compounds with potential to be valorised into food applications.
View Article and Find Full Text PDFChronobiol Int
December 2024
Faculty of Psychology and Educational Sciences, University of Coimbra, Coimbra, Portugal.
This study investigated the impact of age on morningness-eveningness (ME) and its inter-individual variability, with a focus on sex-specific patterns. A sample of 2890 participants aged 12-94 years (55.85% female) completed the Composite Scale of Morningness.
View Article and Find Full Text PDFBMC Pregnancy Childbirth
December 2024
Immunology LATAM, Janssen, Mendoza, Buenos Aires, CP (1428), 1259, Argentina.
Background: Hemolytic disease of the fetus and newborn (HDFN) is a condition due to maternal blood group antibodies targeting antigens in fetal red blood cells, with significant prenatal/perinatal morbidity and mortality. Severe HDFN cases are often associated with alloimmunization against Rhesus D (RhD) or Kell antigens. Information about HDFN epidemiology and treatment in Latin American countries is limited.
View Article and Find Full Text PDFBMC Public Health
December 2024
Rui Nabeiro Biodiversity Chair, MED - Mediterranean Institute for Agriculture, Environment and Development & CHANGE - Global Change and Sustainability Institute, Universidade de Évora, Largo dos Colegiais, Évora, 7004-516, Portugal.
Background: The increased severity of extreme weather and anticipated climate change has intensified heat stress-related mortality worldwide. This study examines the historical short-term effects of heat on mortality in Alentejo, Portugal's warmest region, and projects it up to the end of the century.
Methods: Using data from 1980 to 2015 during warm seasons (May-September), the association between daily mortality by all-causes and mean temperature was examined following a case time series design, applied at both regional and subregional scales.
Can J Anaesth
December 2024
Institute for Medical Education, University of Bern, Bern, Switzerland.
Purpose: Gender disparities in academia are a growing concern, impacting various disciplines, including health care. We aimed to investigate gender-based differences in academic performance, leadership roles, and academic distinction within anesthesiology and critical care medicine.
Source: We conducted electronic searches for relevant articles published in PubMed, CENTRAL, Scopus, Web of Science, Embase, Education Resources Information Center, PsychINFO, and ProQuest from database inception until 23 June 2024.
Eur J Nucl Med Mol Imaging
December 2024
Molecular Imaging and Therapy, Hoag Family Cancer Institute, Newport Beach, CA, USA.
Commun Med (Lond)
December 2024
Department of Computer Science, Technion-Israel Institue of Technology, Haifa, Israel.
Background: Molecular profiling of estrogen receptor (ER), progesterone receptor (PR), and ERBB2 (also known as Her2) is essential for breast cancer diagnosis and treatment planning. Nevertheless, current methods rely on the qualitative interpretation of immunohistochemistry and fluorescence in situ hybridization (FISH), which can be costly, time-consuming, and inconsistent. Here we explore the clinical utility of predicting receptor status from digitized hematoxylin and eosin-stained (H&E) slides using machine learning trained and evaluated on a multi-institutional dataset.
View Article and Find Full Text PDFObjectives: Femoral vein transposition (tFV) is a complex procedure that provides high patency rates for patients with exhausted upper-limb vascular access. Traditionally, the procedure involves a long single incision in the thigh to harvest the femoral vein, but this approach is associated with increased risks of local complications such as infections and haematomas. Skip incisions have shown to lower complication rates and shorten maturation times.
View Article and Find Full Text PDFClin Breast Cancer
November 2024
Biochemistry Unit, Department of Biomedicine, Faculty of Medicine, University of Porto (FMUP), Porto, Portugal; i3S ‑ Instituto de Inovação e Investigação em Saúde, University of Porto, Porto, Portugal; Faculty of Health Sciences, University Fernando Pessoa, Fernando Pessoa Hospital-School (FCS/HEFP/UFP), Porto, Portugal. Electronic address:
Purpose: The aim of this study is to analyse PR independently and its relationship with demographic and clinicopathological information.
Introduction: Steroid hormones, particularly estrogen and progesterone, play a crucial role in breast cancer (BC) etiology. Research attention has focused mainly on estrogen while the progesterone impact on breast cancer has yet to be fully uncover.
J Appl Microbiol
December 2024
VBlab - Laboratory of Bacterial Viruses, University of Sorocaba, 18023-000 Sorocaba/SP, Brazil.
Aims: In this study we report the use of two novel lytic polyvalent phages as a cocktail in in planta assays and its efficacy in the control of bacterial halo blight (BHB) caused by Pseudomonas coronafaciens pv. garcae (Pcg) in coffee plants.
Methods And Results: Phages were isolated from samples of coffee plant leaves collected at two different locations in Brazil.
Eur J Neurol
January 2025
Second Department of Neurology, School of Medicine, "Attikon" University Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Background: Microembolic signals (MES) can be detected using transcranial Doppler (TCD) ultrasound in several clinical scenarios, including acute ischemic stroke (AIS). This narrative review aims to provide insights into their role in AIS patient management and outcomes.
Methods: The present narrative review consolidates current observational and randomized evidence on the prevalence and clinical relevance of MES in different AIS subtypes and settings.
Water Res
December 2024
CERIS, Instituto Superior Técnico, Universidade de Lisboa, Av. Rovisco Pais, Lisboa 1049-001, Portugal.
Green walls for greywater treatment have emerged as a solution to increase green spaces in densely urbanized areas while providing treated greywater for reuse. Over the past decade, numerous studies have focused on optimizing these systems, though most address specific operational conditions and evaluate a limited set of performance parameters. This review synthesizes the existing literature using a meta-analysis to identify key operational factors and treatment performance metrics.
View Article and Find Full Text PDFEur J Obstet Gynecol Reprod Biol
December 2024
Maternal-Fetal Medicine Unit, Department of Obstetrics, Hospital Universitari Vall d'Hebron, Universitat Autònoma de Barcelona, Barcelona, Spain.
Chorioamnionitis is a significant contributor to non-hypoxic fetal compromise, increasing the risk of neonatal encephalopathy and cerebral palsy. This paper highlights the limitations of traditional diagnostic methods for chorioamnionitis, which rely on histopathology, microbiology, and clinical signs, and emphasizes the importance of recognizing the fetal inflammatory response using intrapartum cardiotocography (CTG). By understanding the physiological pathways of inflammation, clinicians can identify characteristic CTG patterns.
View Article and Find Full Text PDF