171,410 results match your criteria: "Portugal; Centre for Health Technology and Services Research CINTESIS[Affiliation]"
Pathogens
January 2025
MicroART-Antibiotic Resistance Team, Department of Veterinary Sciences, University of Trás-os-Montes and Alto Douro, 5000-801 Vila Real, Portugal.
One of the significant challenges facing modern medicine is the rising rate of antibiotic resistance, which impacts public health, animal health, and environmental preservation. Evaluating antibiotic resistance in wildlife and their environments is crucial, as it offers essential insights into the dynamics of resistance patterns and promotes strategies for monitoring, prevention, and intervention. and genera isolates were recovered from fecal samples of wild animals and environmental samples using media without antibiotic supplementation.
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January 2025
Animal and Veterinary Research Centre (CECAV), Associate Laboratory for Animal and Veterinary Sciences (AL4AnimalS), University of Trás-os-Montes e Alto Douro (UTAD), 5000-801 Vila Real, Portugal.
Wild birds may be involved in the transmission of agents of infectious diseases, including zoonoses, a circumstance which raises a number of public and animal health issues. Migratory bird species play a significant role in the introduction of tick-borne pathogens to new geographic areas, contributing to the dissemination of various etiological agents. This preliminary study aimed to assess the occurrence of four potentially zoonotic pathogens ( spp.
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January 2025
Laboratório de Virologia e Rickettsioses, Faculdade de Medicina Veterinária, Universidade Federal de Mato Grosso, Fernando Correa da Costa, 2367, Cuiabá 78060-900, Brazil.
Coronaviruses (CoV) infect a wide variety of hosts, causing epidemics in humans, birds, and mammals over the years. Bats (order Chiroptera) are one of the natural hosts of the Coronaviridae family. They represent 40% of the total number of mammal species in the Pantanal, a biodiversity hotspot in South America.
View Article and Find Full Text PDFSensors (Basel)
January 2025
Institute of Human Movement Science, Sport and Health, University of Graz, 8010 Graz, Austria.
Unlabelled: In recent years, the EnodePro device has been one of the most frequently used velocity sensors to track the bar velocity in resistance training, with the aim of providing load-velocity profiles. However, recent articles highlight a lack of reliability and validity in the estimated maximal strength, which can cause a serious health risk due to the overestimation of the bar velocity. With this study, we aimed to investigate whether imprecision in the measurement could explain the variance in this measurement error.
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January 2025
Centre of Mechanical Technology and Automation (TEMA), Department of Mechanical Engineering, University of Aveiro, 3810-193 Aveiro, Portugal.
To automate the quality control of painted surfaces of heating devices, an automatic defect detection and classification system was developed by combining deflectometry and bright light-based illumination on the image acquisition, deep learning models for the classification of non-defective (OK) and defective (NOK) surfaces that fused dual-modal information at the decision level, and an online network for information dispatching and visualization. Three decision-making algorithms were tested for implementation: a new model built and trained from scratch and transfer learning of pre-trained networks (ResNet-50 and Inception V3). The results revealed that the two illumination modes employed widened the type of defects that could be identified with this system, while maintaining its lower computational complexity by performing multi-modal fusion at the decision level.
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January 2025
Faculty of Minas Gerais (FAMINAS), Muriaé 36888-233, Brazil.
This paper focuses on the modeling, control, and simulation of an over-actuated hexacopter tilt-rotor (HTR). This configuration implies that two of the six actuators are independently tilted using servomotors, which provide high maneuverability and reliability. This approach is predicted to maintain zero pitch throughout the trajectory and is expected to improve the aircraft's steering accuracy.
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January 2025
Instituto de Engenharia de Sistemas e Computadores-Microsistemas e Nanotecnologias (INESC-MN), Rua Alves Redol, 1000-029 Lisbon, Portugal.
Point-of-care (PoC) devices offer a promising solution for fast, portable, and easy-to-use diagnostics. These characteristics are particularly relevant in agrifood fields like viticulture where the early detection of plant stresses is crucial to crop yield. Microfluidics, with its low reagent volume requirements, is well-suited for such applications.
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January 2025
Centro de Química Estrutural, Institute of Molecular Sciences, Departamento de Química e Bioquímica, Faculdade de Ciências, Universidade de Lisboa, Campo Grande, 1749-016 Lisboa, Portugal.
Healthcare-associated infections (HAI) are a critical public health problem, with 30 to 40% of infections related to the urinary tract system. These urinary tract infections (UTIs) are considered one of the most common microbial infections in hospital settings and everyday community contexts, where approximately 80% are highly correlated with urinary catheter insertion, i.e.
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January 2025
2Ai, School of Technology, IPCA, 4750-810 Barcelos, Portugal.
Virtual reality (VR) has gained significant attention in various fields including healthcare and industrial applications. Within healthcare, an interesting application of VR can be found in the field of physiotherapy. The conventional methodology for rehabilitating upper limb lesions is often perceived as tedious and uncomfortable.
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January 2025
Institute for Nanostructures, Nanomodelling and Nanofabrication (i3N), Department of Physics, University of Aveiro, 3810-193 Aveiro, Portugal.
Invisible health monitoring is currently a topic of global interest within the scientific community. Sensorization of everyday objects can provide valuable health information without requiring any changes in people's routines. In this work, a feasibility study of photoplethysmography (PPG) acquisition in the lower limbs for continuous and real-time monitoring of the vital signs, including heart rate (HR) and respiratory rate (RR), is presented.
View Article and Find Full Text PDFJ Clin Med
January 2025
Precision Medicine Unit, Department of Gastroenterology, São João University Hospital, Alameda Professor Hernâni Monteiro, 4200-427 Porto, Portugal.
Several artificial intelligence systems based on large language models (LLMs) have been commercially developed, with recent interest in integrating them for clinical questions. Recent versions now include image analysis capacity, but their performance in gastroenterology remains untested. This study assesses ChatGPT-4's performance in interpreting gastroenterology images.
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January 2025
H&TRC-Health & Technology Research Center, ESTeSL-Escola Superior de Tecnologia da Saúde, Instituto Politécnico de Lisboa, 1990096 Lisbon, Portugal.
Age-related macular degeneration (AMD) is a global cause of vision loss, with limited therapeutic options highlighting the need for effective biomarkers. This study aimed to characterize plasma DNA methyltransferase expression (, , and ) in AMD patients and explore divergent expression patterns across different stages of AMD. : Thirty-eight AMD patients were prospectively enrolled and stratified by disease severity: eAMD, iAMD, nAMD, and aAMD.
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January 2025
Precision Medicine Unit, Department of Gastroenterology, São João University Hospital, 4200-427 Porto, Portugal.
An important impediment to the incorporation of artificial intelligence-based tools into healthcare is their association with so-called black box medicine, a concept arising due to their complexity and the difficulties in understanding how they reach a decision. This situation may compromise the clinician's trust in these tools, should any errors occur, and the inability to explain how decisions are reached may affect their relationship with patients. Explainable AI (XAI) aims to overcome this limitation by facilitating a better understanding of how AI models reach their conclusions for users, thereby enhancing trust in the decisions reached.
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January 2025
Social and Behavioral Sciences Department, University of Maia, 4475-690 Maia, Portugal.
Violence in intimate relationships (IPV) is understood as one of the most common forms of violence, being maintained by cultural habits and customs, and legitimized from generation to generation. This study aims at a comprehensive review of the literature on IPV, the relationship between the stages of change, maintenance factors, and the decision to keep or leave the violent partner. A comprehensive literature search was conducted to identify journal articles focused on IPV, following online databases as well as a manual review from relevant peer-reviewed journals.
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January 2025
Centro de Investigação em Química (CIQUP), Institute of Molecular Sciences (IMS), Department of Chemistry and Biochemistry, Faculty of Sciences, University of Porto, Rua do Campo Alegre, 4169-007 Porto, Portugal.
An extensive thermochemical study of γ-undecanolactone and δ-undecanolactone has been developed using two complementary calorimetric techniques. The combustion energy of each compound was determined by static-bomb combustion calorimetry, and the corresponding enthalpy of vaporization was determined by high-temperature Calvet microcalorimetry, in which both properties of each compound are reported at = 298.15 K.
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January 2025
Unit of Biochemistry, Department of Biomedicine, Faculty of Medicine of Porto, University of Porto, 4200-319 Porto, Portugal.
The prevalence of metabolic syndrome has been exponentially increasing in recent decades. Thus, there is an increasing need for affordable and natural interventions for this disorder. We explored the effect of chrysin, a dietary polyphenol, on hepatic lipid and glycogen accumulation, metabolic dysfunction-associated fatty liver disease (MAFLD) activity score and oxidative stress and on hepatic and adipose tissue metabolism in rats presenting metabolic syndrome-associated conditions.
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January 2025
Centro de Ciências e Tecnologias Nucleares (C2TN), Instituto Superior Técnico, Universidade de Lisboa, E.N. 10 ao km 139.7, 2695-066 Bobadela LRS, Portugal.
The wine industry generates high amounts of waste, posing current environmental and economic sustainability challenges. Grape pomace, mainly composed of seeds, skins, and stalks, contains significant amounts of bioactive compounds and constitutes the main solid residue of this industry. Various strategies are being explored for its valorization, from a circular economy perspective.
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January 2025
Laboratório de Química Orgânica e Farmacêutica, Departamento de Ciências Químicas, Faculdade de Farmácia, Universidade do Porto, Rua Jorge Viterbo Ferreira, 228, 4050-313 Porto, Portugal.
New psychoactive substances (NPSs) emerged in the 2000s as legal alternatives to illicit drugs and quickly became a huge public health threat due to their easy accessibility online, limited information, and misleading labels. Synthetic cannabinoids and synthetic cathinones are the most reported groups of NPSs. Despite NPSs being widely studied, due to their structural diversity and the constant emergence of novel compounds with unknown properties, the development of new techniques is required to clarify their mode of action and evaluate their toxicological effects.
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January 2025
Neuroscience and Signalling Group, Institute of Biomedicine (iBiMED), Department of Medical Sciences, University of Aveiro, 3810-193 Aveiro, Portugal.
Alzheimer's disease is a challenge in modern healthcare due to its complex etiology and increasing prevalence. Despite advances, further understanding of Alzheimer's disease pathophysiology is needed, particularly the role of Aβ neurotoxic peptide. Fourier transform infrared spectroscopy (FTIR) has shown potential as a screening tool for several pathologies, including Alzheimer's disease.
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January 2025
REQUIMTE/LAQV, ISEP, Polytechnic of Porto, Rua Dr. António Bernardino de Almeida, 431, 4200-072 Porto, Portugal.
Fruits are essential components of the human diet, valued for their diverse bioactive compounds with potential health-promoting properties. This study focuses on three cold-hardy species, namely , , and , examining their polyphenolic content, antioxidant/antiradical activities, scavenging capacity and effects on intestinal cell viability (Caco-2 and HT29-MTX). A comprehensive profile of their phenolic compounds was identified, in descending order of total polyphenol content: > > .
View Article and Find Full Text PDFMaterials (Basel)
January 2025
DENS-ia Research Group, Faculty of Health Sciences, Miguel de Cervantes European University, C/del Padre Julio Chevalier 2, 47012 Valladolid, Spain.
A comparative analysis has been carried out between three different dental materials suitable for the prostheses manufacturing. The analysis performed is based on the finite elements method (FEM) and was made to evaluate their performance under three different loading conditions. Three different materials were modeled with 3D CAD geometry, all of them suitable to be simulated by means of a linear elastic model.
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January 2025
Federal Institute of Education, Science and Technology of Rio Grande do Norte (IFRN), São Gonçalo do Amarante 59291-727, Brazil.
The durability of reinforced concrete is associated with several factors that can trigger the corrosion of reinforcement bars. Among these factors, the most significant are chloride-ion attack and carbonation. This study evaluated, through accelerated testing, self-compacting concretes (SCCs) with reduced cement content in binary, ternary, and quaternary mixtures using high-early-strength Portland cement, fly ash (FA), metakaolin (MK), and hydrated lime (HL).
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January 2025
Laboratory of Materials Technology, Department of Materials Engineering, Federal University of Campina Grande, Campina Grande 58400-850, Brazil.
Over the past 15 years, there has been a significant increase in the search for environmentally friendly energy sources, and transition-metal-based energy storage devices are leading the way in these new technologies. Supercapacitors are attractive in this regard due to their superior energy storage capabilities. Electrode materials, which are crucial components of supercapacitors, such as cobalt-oxide-based electrodes, have great qualities for achieving high supercapacitor performance.
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January 2025
CITAB-Centre for the Research and Technology of Agro-Environmental and Biological Sciences, School of Science and Technology, University of Trás-os-Montes and Alto Douro, 5000-801 Vila Real, Portugal.
Epoxy resins are extensively employed as adhesives and matrices in fibre-reinforced composites. As polymers, they possess a viscoelastic nature and are prone to creep and stress relaxation even at room temperature. This phenomenon is also responsible for time-dependent failure or creep fracture due to cumulative strain.
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January 2025
Department of Electromechanical Engineering, University of Beira Interior, Rua Marquês de D'Ávila e Bolama, 6201-001 Covilhã, Portugal.
This study investigates the mechanical properties of thermoplastic polyurethane (TPU) 60A, which is a flexible material that can be used to produce soft robotic grippers using additive manufacturing. Tensile tests were conducted under ISO 37 and ISO 527 standards to assess the effects of different printing orientations (0°, 45°, -45°, 90°, and quasi-isotropic) and test speeds (2 mm/min, 20 mm/min, and 200 mm/min) on the material's performance. While the printing orientations at 0° and quasi-isotropic provided similar performance, the quasi-isotropic orientation demonstrated the most balanced mechanical behavior, establishing it as the optimal choice for robust and predictable performance, particularly for computational simulations.
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