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Immunohistochemical expression of TLR-4 in temporomandibular joint dysfunction.
Cranio
September 2019
e School of Health and Bioscience, Pontifical Catholic University of Parana State, Curitiba , Brazil.
Toll-like receptor 4 (TLR-4) is a transmembrane protein involved in the innate immune system and has been implicated in the pathogenesis of temporomandibular joint dysfunction (TMD). The purpose of this study was to histologically examine the level of expression of TLR-4 relative to severity of TMD. Thirty-one human TMJ disc samples were immunostained for TLR-4 and evaluated for intensity of stain.
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