406 results match your criteria: "Pontifical Catholic University of Chile.[Affiliation]"

Medial Meniscus Ramp Tears: State of the Art.

J ISAKOS

December 2024

Twin Cities Orthopedics, Edina, Minnesota, USA. Electronic address:

Medial meniscus ramp tears are tears of the posteromedial capsule or peripheral rim of the posteromedial meniscus that frequently occur with anterior cruciate ligament (ACL) tears. The incidence and prevalence of medial meniscus ramp tears has been increasing in the recent literature due to the increased understanding of the anatomy and diagnosis of these tears. When a patient presents with an ACL tear, a medial meniscus ramp tear should be suspected if the patient has a grade 3+ Lachman or pivot shift exam, a vertical line of increased signal intensity in the posterior capsule or peripheral meniscus on magnetic resonance imagining (MRI), or posteromedial tibial plateau bone bruising on MRI.

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Low-energy light ion beams are an essential resource in lithography for nanopatterning magnetic materials and interfaces due to their ability to modify the structure and properties of metamaterials. Here we create ferromagnetic/non-ferromagnetic heterostructures with a controlled layer thickness and nanometer-scale precision. For this, hydrogen ion (H) irradiation is used to reduce the antiferromagnetic nickel oxide (NiO) layer into ferromagnetic Ni with lower fluence than in the case of helium ion (He) irradiation.

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Over the last two decades, the rise of the dynamicist view in the philosophy of spacetime theories has motivated a discussion about the way in which chronogeometric structure and dynamics are connected. Geometricists defend that chronogeometry determines and explains dynamics, whereas dynamicists state that it is the other way around. Both parties assume that the arrow of explanation at issue involves a claim of fundamentality and priority of one of the elements over the other.

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The disadvantaged populations eGFR (estimated glomerular filtration rate) epidemiology (DEGREE) study was designed to gain insight into the burden of chronic kidney disease (CKD) of undetermined cause (CKDu) using standard protocols to estimate the general-population prevalence of low eGFR internationally. Therefore, we estimated the age-standardized prevalence of eGFR under 60 ml/min per 1.73m in adults aged 18-60, excluding participants with commonly known causes of CKD; an ACR (albumin/creatinine ratio) over 300 mg/g or equivalent, or self-reported or measured (HT) hypertension or (DM) diabetes mellitus, stratified by sex and location.

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  • The text discusses the importance of forecasting future health issues in the USA for effective planning and public awareness regarding disease and injury burdens.
  • It describes the methodology for predicting life expectancy, cause-specific mortality, and disability-adjusted life-years (DALYs) from 2022 to 2050 using the Global Burden of Diseases framework.
  • The forecasting includes various scenarios to assess the potential impacts of health risks and improvements across the country, focusing on demographic trends and health-related risk factors.
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Performance of Ti/TiO-ZIF-67 photoanode under LED irradiation applied to the photoelectrodegradation of the antidepressant venlafaxine (VEN) in municipal wastewater effluent.

J Environ Manage

January 2025

São Paulo State University (UNESP), Institute of Chemistry, Department of Analytical Chemistry, National Institute of Alternative Technologies for Detection, Toxicological Assessment and Removal of Micropollutants and Radioactive (INCT-DATREM), Rua Professor Francisco Degni, 55, Araraquara, 14800-060, São Paulo, Brazil.

This work describes the direct deposition of ZIF-67 metal-organic framework (MOF) onto Ti/TiO nanotubes forming a photoanode for the degradation of the antidepressant Venlafaxine (VEN). This material combines the excellent characteristics of ZIF-67 MOF in enhancing photocatalytic reduction and oxidation reactions induced by UV LED irradiation, as well as the storage of VEN molecules in its pores. Ti/TiO-ZIF-67 features an eco-friendly technology for degradation of pharmaceutical micropollutants such as antidepressants.

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  • The DEGREE study explored the impact of chronic kidney disease of undetermined cause (CKDu) globally by analyzing the prevalence of low estimated glomerular filtration rate (eGFR) in adults aged 18-60, focusing on participants without known CKD causes.
  • The study included data from 60,964 participants across 43 areas in 14 countries collected from 2007 to 2023, revealing the highest CKDu prevalence in rural areas of Uddanam, India, and Northwest Nicaragua (14%).
  • The findings indicate that CKDu is notably prevalent in specific regions, especially within Central America and South Asia, prompting the need for global monitoring while acknowledging the potential existence of unidentified disease clusters elsewhere.
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Cerebral ischemic injury occurs when blood flow drops below a critical level, resulting in an energy failure. The progressive transformation of hypoperfused viable tissue, the ischemic penumbra, into infarction is a mechanism shared by patients with ischemic stroke if timely reperfusion is not achieved. Yet, the pace at which this transformation occurs, known as the infarct growth rate (IGR), exhibits remarkable heterogeneity among patients, brain regions, and over time, reflecting differences in compensatory collateral flow and ischemic tolerance.

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Surgical treatment for uncommon malignancies of the paranasal sinuses and anterior cranial fossa: report of two cases and literature review.

Int J Oral Maxillofac Surg

November 2024

Oral and Maxillofacial Surgery, Ruber International Hospital, Madrid, Spain; Dentistry School, Faculty of Medicine, Pontifical Catholic University of Chile, Santiago, Chile; Surgical Oncology and Maxillofacial Surgery Department, Faculty of Medicine, Pontifical Catholic University of Chile, Santiago, Chile.

Malignant tumors of the nasal and paranasal cavities account for only 3-5% of all head and neck neoplasms. Among these tumors, rare instances of human papillomavirus (HPV)-positive multiphenotypic carcinomas and biphenotypic sarcomas have been documented. Two such cases are reported here, along with the respective treatment approaches.

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  • CRUSE® is an app designed for people with chronic spontaneous urticaria (CSU) to track their symptoms using visual analogue scales (VASs), aiming to assess the app's effectiveness in measuring disease activity.
  • A study analyzed three VASs related to CSU impact on daily life, including one specifically for the severity of urticaria, one for productivity, and a general health measure (EQ-5D), using data from nearly 6,000 patients over many days.
  • The results showed that the CRUSE® app's VASs demonstrate strong validity and reliability, with the "VAS urticaria" being most effective in capturing symptom changes, while the minimal important difference (MID) values indicated meaningful changes
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Background: This study aimed to review the clinical, radiographic, and magnetic resonance imaging (MRI) outcomes of osteochondral autograft transplantation applied to patellar cartilage lesions of patients under 18 years of age.

Methods: Data from nine consecutive patients were retrospectively analyzed for indications, preoperative complications, and clinical-radiographic outcomes. Patients were clinically evaluated using the Pedi-IKDC and Lysholm scores.

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The Equatorial Pacific Region (EPR) in Ecuador is characterized by high rates of vegetation diversity, and rapid loss of vegetation cover due to anthropogenic pressures. In this study, general ecological aspects of the Tabanidae family, including richness, endemism, and seasonality, were evaluated. Analyses reveal that approximately 42% of the species recorded for Ecuador are present in the EPR, and out of the 84 species cataloged in the EPR, 6 are endemic, representing an endemism of 7.

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Global differences in the management of alcohol-associated hepatitis.

Lancet Gastroenterol Hepatol

November 2024

Department of Gastroenterology, School of Medicine, Pontifical Catholic University of Chile, Santiago, Chile; Observatorio Multicéntrico de Enfermedades Gastrointestinales (OMEGA), Santiago, Chile; Division of Gastroenterology, Hepatology, and Nutrition, Department of Internal Medicine, Virginia Commonwealth University School of Medicine, Richmond, VA 23284, USA. Electronic address:

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Uterine intravascular leiomyomatosis (IVL) with extension into the right heart is uncommon, with no more than 400 cases reported in the literature since 1907. The present study aims to report three patients with intracardiac IVL surgically treated in our institution, with long-term follow-up. Three female patients in their third to fifth decades of life, with a history of difficult hysterectomy due to extensive myomatosis, presented with symptoms of right-sided heart failure.

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Emergent reperfusion, most commonly with the administration of thrombolytic agents, is the recommended management approach for patients presenting with high-risk, or hemodynamically unstable pulmonary embolism. However, a subset of patients with a more catastrophic presentation, including refractory shock and impending or active cardiopulmonary arrest, may require immediate circulatory support. Venoarterial extracorporeal membrane oxygenation (VA-ECMO) can be deployed rapidly by the well-trained team and provide systemic perfusion allowing for hemodynamic stabilization.

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Myocardial reperfusion injury (MRI) accounts for up to 50% of the final size in acute myocardial infarction and other conditions associated with ischemia-reperfusion. Currently, there is still no therapy to prevent MRI, but it is well known that oxidative stress has a key role in its mechanism. We previously reduced MRI in rats through a combined antioxidant therapy (CAT) of ascorbic acid, N-acetylcysteine, and deferoxamine.

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Gastrointestinal (GI) bleeding is the most common GI diagnosis leading to hospitalization within the United States. Prompt diagnosis and treatment of GI bleeding is critical to improving patient outcomes and reducing high healthcare utilization and costs. Radiologic techniques including computed tomography angiography, catheter angiography, computed tomography enterography, magnetic resonance enterography, nuclear medicine red blood cell scan, and technetium-99m pertechnetate scintigraphy (Meckel scan) are frequently used to evaluate patients with GI bleeding and are complementary to GI endoscopy.

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This article presents the results of almost nine months of ethnographic research on the relationship between physical exercise and health in older people in the post-COVID-19 context. Via exploratory-descriptive qualitative research and the use of a convenient sample, I shed light on this relationship using the stories and life experiences of 40 older people (10 men and 30 women, including two women instructors for senior classes) who exercise regularly. The meanings they attributed to physical exercise during COVID-19 and after it are explained, emphasising first that there is no health in a context of not feeling safe; once there is a feeling of security, the most relevant meanings can be exposed in three directions.

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Decolonising global health: why the new Pandemic Agreement should have included the principle of subsidiarity.

Lancet Glob Health

July 2024

Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, Old Road Campus, Oxford, UK; University of Ghana, Accra, Ghana. Electronic address:

The negotiations for the WHO Pandemic Agreement have brought attention to issues of racism and colonialism in global health. Although the agreement aims to promote global solidarity, it fails to address these deeply embedded problems. This Viewpoint argues that not including the principle of subsidiarity into Article 4 of the agreement as a pragmatic strategy was a missed opportunity to decolonise global health governance and promote global solidarity.

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Article Synopsis
  • * A review of HR-US examinations was conducted for 16 patients, gathering data on demographics, clinical suspicions, and imaging findings.
  • * The results highlighted that HR-US provides clear imaging of OCST features, indicating inflammation and aiding in differential diagnosis, especially when other conditions like epidermal cysts are suspected.
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Most alcohol intervention research focuses on program efficacy, yet few studies have investigated the acceptability of a program's design and implementation to the target population or adapting existing alcohol interventions to different populations. To address these gaps in the literature, we (1) examined participant responsiveness to and implementation quality of FITSTART+, a web-app delivered parent-based alcohol intervention designed for incoming first-year college students in the United States, and (2) gathered feedback on how this intervention could be adapted to other populations of parents. A sample of U.

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Objective: Cleft lip and palate is the most common craniofacial birth anomaly and requires surgery in the first year of life. However, craniofacial surgery training opportunities are limited. The aim of this study was to present and evaluate an open-source cleft lip and palate hybrid (casting and three-dimensional (3D) printing) simulation model which can be replicated at low cost to facilitate the teaching and training of cleft surgery anatomy and techniques.

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Recent studies have expanded the genomic contours of the , highlighting important lacunae in our comprehension of the phylogenetic space occupied by certain lineages of the class. One such lineage is ', a novel genus-level taxon, represented by ' VAN18-1 as its type species, along with two other uncultivated metagenome-assembled genomes (MAGs) originating from geothermally active sites across the Pacific Ring of Fire. In this study, we investigate the genetic and genomic diversity, and the distribution patterns of several uncharacterized class strains and sequence clones, which are ascribed to the same 16S rRNA gene sequence clade.

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