The Long-Term Outcomes of Inactive Pacemaker Lead Abandonment in Children and Dramatic Observation of Complications.

Transvenous extraction of the leads in children is associated with a higher risk of serious complications, that is why it is reluctantly performed. Unfortunately, this conservative approach has been associated with secondary complications (tricuspid valve dysfunction and bilateral venous obstruction), adverse events during lead removal procedure and recanalization and stenting of chest veins. We present a case of a 27-year-old female with a pacemaker and insertion of two new leads on the opposite side of the chest leaving the old ones in place.

Life-Threatening Esophageal Variceal Hemorrhage in a 7-Year-Old Boy with Massive Portal Vein Enlargement Due to Congenital Arterioportal Fistula.

BACKGROUND Arterioportal fistulas (APFs) are abnormal connections between the arterial and portal venous systems, leading to portal hypertension (PH) and symptoms such as gastrointestinal bleeding, splenomegaly, and hepatic pain. Symptoms typically appear by the age of 2 years in about 75% of cases. CASE REPORT A 7-year-old boy with an asymptomatic APF developed life-threatening complications following a Clostridium difficile infection.

LCRAnnotationsDB: a database of low complexity regions functional and structural annotations.

Low Complexity Regions (LCRs) are segments of proteins with a low diversity of amino acid composition. These regions play important roles in proteins. However, annotations describing these functions are dispersed across databases and scientific literature.

Decoding the physicochemical basis of resurrection: the journey of lichen Flavoparmelia caperata through prolonged water scarcity to full rehydration.

Desiccation tolerance is a complex phenomenon observed in the lichen Flavoparmelia ceparata. To understand the reactivation process of desiccated thalli, completely dried samples were rehydrated. The rehydration process of this lichen occurs in two phases.

Test, track, treat using wearable sensors for management of Parkinson's disease: 12‑month prospective observational United Arab Emirates study using Parkinson's Kinetograph (EmPark-PKG Study).

Parkinson's disease (PD) is a progressive neurodegenerative disorder marked by both motor and non-motor symptoms that necessitate ongoing clinical evaluation and medication adjustments. Home-based wearable sensor monitoring offers a detailed and continuous record of patient symptoms, potentially enhancing disease management. The EmPark-PKG study aims to evaluate the effectiveness of the Parkinson's KinetoGraph (PKG), a wearable sensor device, in monitoring and tracking the progression of motor symptoms over 12 months in Emirati and non-Emirati PD patients.

Personality traits and their correlation with behavior in the bonnet macaque (Macaca radiata) in southern India.

The purpose of our research was to identify the primary personality traits of bonnet macaques using an observer-based questionnaire and to assess the accuracy of this method in predicting behavior. Additionally, we examined the relationship between personality traits and variables such as sex, age, and rank. We rated 25 males and 38 females on 50 personality questionnaire items using a 7-point scale, with reliable ratings and good agreement among raters (the lowest of the calculated ICC (3:k) index ≥ 0.

Testing the Dispersal-Origin-Status-Impact (DOSI) scheme to prioritise non-native and translocated species management.

Assessing actual and potential impacts of non-native species is necessary for prioritising their management. Traditional assessments often occur at the species level, potentially overlooking differences among populations. The recently developed Dispersal-Origin-Status-Impact (DOSI) assessment scheme addresses this by treating biological invasions as population-level phenomena, incorporating the complexities affecting populations of non-native species.

Disease-specific complaints among multiple myeloma patients treated with chemotherapy, autotransplantation and supportive therapy in Poland: a cross-sectional study.

Due to its course, multiple myeloma may negatively affect the functioning of patients. Different treatment methods are also associated with patients' varying perception of their health condition. The purpose of this study is to determine the disease-specific complaints among multiple myeloma patients during selected treatment methods-chemotherapy, autologous hematopoietic stem cell transplantation, and supportive therapy.

Defining the role of Hmu and Hus systems in Porphyromonas gingivalis heme and iron homeostasis and virulence.

Iron and heme are essential nutrients for all branches of life. Pathogenic members of the Bacteroidota phylum, including Porphyromonas gingivalis, do not synthesize heme and rely on host hemoproteins for heme as a source of iron and protoporphyrin IX. P.

Mirror-invariance is not exclusively visual but extends to touch.

Mirror-invariance enables recognition of mirrored objects as identical. During reading acquisition, sighted readers must overcome this innate bias to distinguish between mirror-inverted letters ('d' vs. 'b').

Social conditions of smallholder dairy farmers influence their environmental decisions.

The objective of this study is to characterize the social conditions for making agricultural decisions. Particular attention is paid to sustainable agricultural practices in dairy farming. The theoretical framework has been developed around two major explicatory perspectives: sustainable development and quality of life.

Extreme learning machine for identifying soil-dwelling microorganisms cultivated on agar media.

The aim of this research is to create an automated system for identifying soil microorganisms at the genera level based on raw microscopic images of monocultural colonies grown in laboratory environment. The examined genera are: Fusarium, Trichoderma, Verticillium, Purpureolicillium and Phytophthora. The proposed pipeline deals with unprocessed microscopic images, avoiding additional sample marking or coloration.

Carboxyl ester lipase hybrid 1 (CEL-HYB1) haplotypes confer varying risk for chronic pancreatitis.

The CEL-HYB1 hybrid allele of the carboxyl ester lipase (CEL) gene and its pseudogene (CELP) has been associated with chronic pancreatitis (CP). Recent work indicated that amino acid positions 488 and 548 in CEL-HYB1 determined pathogenicity. Haplotype Thr488-Ile548 was associated with CP while haplotypes Thr488-Thr548 and Ile488-Thr548 were benign.

Neural processing of sad and happy autobiographical memories in women with depression and borderline personality disorder.

Patients with major depressive disorder (MDD) and borderline personality disorder (BPD) are reported to have disrupted autobiographical memory (AM). Using functional magnetic resonance imaging we investigated behavioral and neural processing of the recall of emotional (sad and happy) memories in 30 MDD, 18 BPD, and 34 healthy control (HC) unmedicated women. The behavioral results showed that the MDD group experienced more sadness than the HC after the sad recall, while BPD participants experienced less happiness than HC after the happy recall.

Preventive maintenance in urban public transport: the role of engine oil analysis.

Engine oil is a valuable source of information on the technical condition of the drive unit. Under the influence of many factors, including operating conditions, time, high temperature, and various types of contamination, the oil gradually degrades, which can result in serious engine damage. The subject of the article focuses on an attempt to answer the questions of how engine failure affects the degradation of engine oil and whether we can use this knowledge to detect potential problems in public transport vehicles at an early stage.

The complex anatomy of the bronchial arteries: a meta-analysis with potential implications for thoracic surgery and hemoptysis treatment.

The present meta-analysis aimed to provide the most detailed and comprehensive anatomical description of bronchial arteries (BAs) using data available in the literature. Adequate knowledge of the normal anatomy and morphological variations of BAs can be clinically significant; for example, this approach can prevent potential risks while undertaking bronchial artery embolization (BAE) procedures and, ultimately, lead to better patient outcomes. Major medical databases such as PubMed, Scopus, Embase, Web of Science, Google Scholar, and the Cochrane Library were searched.

Acyl-CoA: lysophosphatidylcholine acyltransferase from diatom P. Tricornutum efficiently remodels phosphatidylcholine containing polyunsaturated fatty acids.

This study presents characterisation of diatom's PtLPCAT1 (acyl-CoA: lysophosphatidylcholine acyltransferase) activity in phospholipid remodelling. In this research microsomal fractions of yeast Δale1 mutant overexpressing PtLPCAT1 were used as a source of the tested enzyme. In the assays evaluating remodelling of different phospholipids by PtLPCAT1 not modified microsomal fractions of the tested yeast were used.

PCNA and Rnh1 independently participate in the protection of mitochondrial genome against UV-induced mutagenesis in yeast cells.

In Saccharomyces cerevisiae cells, the bulk of mitochondrial DNA (mtDNA) replication is mediated by the replicative high-fidelity DNA polymerase γ. However, upon UV irradiation low-fidelity translesion polymerases: Polη, Polζ and Rev1, participate in an error-free replicative bypass of UV-induced lesions in mtDNA. We analysed how translesion polymerases could function in mitochondria.

LED light improves shoot multiplication, steviol glycosides and phenolic compounds biosynthesis in Stevia rebaudiana Bertoni in vitro culture.

Light-emitting diode (LED) lamps are efficient elicitors of secondary metabolites. To investigate the influence of LED light on steviol glycosides (SGs) and phenolic compounds biosynthesis, stevia shoots were cultured under the following LED lights: white-WL, blue-B, red-R, 70% red and 30% blue-RB, 50% UV, 35% red and 15% blue-RBUV, 50% green, 35% red and 15% blue-RBG, 50% yellow, 35% red and 15% blue-RBY, 50% far-red, 35% red and 15% blue-RBFR and white fluorescent light (WFl, control). RBG light stimulated shoots' biomass production.

A proficient approach for the classification of Alzheimer's disease using a hybridization of machine learning and deep learning.

Alzheimer's disease (AD) is a neurodegenerative disorder. It causes progressive degeneration of the nervous system, affecting the cognitive ability of the human brain. Over the past two decades, neuroimaging data from Magnetic Resonance Imaging (MRI) scans has been increasingly used in the study of brain pathology related to the birth and growth of AD.

Changes in various forms of fibronectin in patients undergoing coronary artery bypass grafting with cardiopulmonary bypass - a prospective, observational study.

Coronary artery bypass grafting (CABG) with cardiopulmonary bypass (CPB) is associated with the transient activation of a systemic inflammatory response. Fibronectin (FN), an endogenous inflammatory mediator, is a key component of the extracellular matrix. This study aimed to detect changes in cellular and plasma FN levels, as well as its potential fragmentation or FN-fibrin complex formation, in 40 patients undergoing CABG with CPB.

Magnetoacoustic wave propagation in the solar corona and filament dynamics.

The formation of a S-shaped filament was investigated to determine if and how magnetoacoustic waves in the solar corona can trigger filament excitation. The study investigated how magnetoacoustic waves interact with two magnetic null points in the solar corona. Since the solar corona has a complex magnetic field structure, it is expected that magnetic structures are predominantly responsible for the occurrence of coronal events.

Hygienic behaviors and use of dental care in patients with genetic syndromes.

Patients with genetic syndromes require special dental attention because they have symptoms that promote plaque accumulation, dental erosion, dental caries and gingival diseases. The aim of the study was to assess hygienic behaviors, use of dental care and frequency of professional preventive procedures among Polish children and adolescents with Prader-Willi, Down, Angelman, Silver-Russell and Smith-Lemli-Opitz syndromes. Parents/legal guardians of children and adolescents with genetic syndromes were included.

Pregnancy-induced mechanisms regulating central and peripheral leptin sensitivity: lessons from sheep.

This review describes various aspects of the leptin resistance phenomenon and related physiological mechanisms that occur in pregnant sheep. Its main aim is to analyze the mechanisms that determine the occurrence of pregnancy-induced leptin resistance and to investigate the accompanying processes that affect the physiology of pregnancy and lactation in livestock. The main purpose of this analysis was to comprehensively understand the phenomenon of leptin resistance, including the causes of its emergence and its effects on nonrodent organisms.