Evaluation of the Antioxidant Properties and Biological Effects of a Novel Combined Barberry Root-Propolis Extract on HEK293T Cells.

The health benefits of honeybee products and herbs are well known, and their appropriate combination may enhance their biological efficacy. This study investigated the biological properties of a combined barberry root and propolis extract (PBE) in comparison to a propolis extract (PE), a barberry root extract (BE), and pure berberine (BN). The antioxidant properties were evaluated using DPPH and FRAP methods and total phenolic contents (TPC) were assessed by the Folin-Ciocalteu method.

Kojic Acid Derivative as an Antimitotic Agent That Selectively Kills Tumour Cells.

The primary method used to pharmacologically arrest cancer development and its metastasis is to disrupt the cell division process. There are a few approaches that may be used to meet this objective, mainly through inhibiting DNA replication or mitosis. Despite intensive studies on new chemotherapeutics, the biggest problem remains the side effects associated with the inhibition of cell division in non-tumoural host cells.

Downregulation of Ezrin Suppresses Migration Potential in Cervical Cancer Cells.

Background: The literature reports that ezrin (EZR) is important as a linker between microfilaments and cellular environments. Moreover, it affects cancer cell migration, but the exact mechanism is not fully understood. In this study, we aimed to investigate the role of EZR in the migration of two different types of cervical cancer cells-from primary lesion (SiHa) and lymph node metastases (HT-3).

A Case of Dibothriocephalosis () from Iseo Lake (Northern Italy): An Update on a Persistent Sanitary Issue.

Dibothriocephalosis is a fish-borne parasitic zoonosis that is caused by tapeworms of the (syn. ) genus. This paper describes a human case of dibothriocephalosis associated with the consumption of a presumably infected fish, prepared at a restaurant near Iseo Lake (northern Italy).

Seroprevalence of , , , , , , and in Human Population from Eastern Poland.

The epidemiological situation related to infectious diseases is influenced by many factors. To monitor actual trends in selected zoonoses, a total of 473 serum samples from farmers, forestry workers, and veterinarians were collected for serological examination. Anti- sensu lato (s.

Parasites in Sewage: Legal Requirements and Diagnostic Tools.

Despite the vast amount of water on Earth, only a small percent is suitable for consumption, and these resources are diminishing. Moreover, water resources are unevenly distributed, leading to significant disparities in access to drinking water between countries and populations. Increasing consumption and the expanding human population necessitate the development of novel wastewater treatment technologies and the use of water treatment byproducts in other areas, such as fertilisers.

Antibiotic Susceptibility Patterns and Virulence Profiles of Classical and Hypervirulent Strains Isolated from Clinical Samples in Khyber Pakhtunkhwa, Pakistan.

The emergence of hypervirulent and carbapenem-resistant hypermucoviscous strains presents a significant public health challenge due to their increased virulence and resistance to multiple antibiotics. This study evaluates the antibiotic susceptibility patterns and virulence profiles of classical and hypervirulent strains isolated from various clinical samples. A total of 500 clinical samples were collected from patients at the Mardan Medical Complex and Ayub Medical Complex in KPK between July 2022 and June 2024.

Use of Tick Cell Lines in Co-Infection Studies with a Preliminary Study of Co-Culture of and .

is an important vector of infectious human and livestock diseases in Europe. Co-infections of pathogens in ticks and hosts have been reported. Tick cell lines offer a useful model system for study of co-infections.

Detection and Whole-Genome Characteristics of Isolated from Captive Snakes.

is a rare member of the genus , primarily associated with human wound infections rather than respiratory diseases. The bacterium has been isolated from various clinical specimens, including ear inflammatory discharge, diabetic ulcers, and chronic wounds. The study aimed to characterize the genomes and antimicrobial resistance (AMR) profiles of obtained from the fecal samples of asymptomatic highland eyelash pit vipers ().

Relationships Between and the Rest of the World-Analysis of Dual-Species Biofilms and Infections.

In this study, we investigated the interactions between and , , , and in mixed infections. Initially, these interactions were studied qualitatively and quantitatively in dual-species biofilms formed in vitro. The MTT assays, determination of the total CFU/mL, and SEM analysis showed that interacted differentially with the other spp.

Morphological and Chemical Changes in the Hemolymph of the Wax Moth Infected by the Entomopathogenic Fungus .

Hemolymph enables communication between organs in insects and ensures necessary coordination and homeostasis. Its composition can provide important information about the physiological state of an insect and can have diagnostic significance, which might be particularly important in the case of harmful insects subjected to biological control. Linnaeus 1758 (Lepidoptera: Pyralidae) is a global pest to honey bee colonies.

Differentiation of and by Metabolite Profiles Obtained Using Gold Nanoparticles-Based Surface-Assisted Laser Desorption/Ionization Mass Spectrometry.

and are challenging to differentiate using methods such as phenotyping, 16S rRNA sequencing, or protein profiling through matrix-assisted laser desorption/ionization mass spectrometry (MALDI MS) due to their close relatedness. This study explores the potential for identifying and by incorporating reference spectra of metabolite profiles, obtained via surface-assisted laser desorption/ionization mass spectrometry (SALDI MS) employing gold nanoparticles (AuNPs), into the Bruker Biotyper database. Metabolite extracts from and cells were prepared using liquid-liquid extraction in a chloroform-methanol-water system.

First Report of SNPs Detection in TMEM154 Gene in Sheep from Poland and Their Association with SRLV Infection Status.

Small ruminant lentiviruses (SRLVs) infect sheep, causing a multiorganic disease called maedi-visna or ovine progressive pneumonia, which significantly affects the production and welfare of sheep, generating serious economic losses. Although not all infected animals develop fully symptomatic disease, they constantly spread the virus in the flock. Since the infection is incurable and no vaccine is available, another approach is necessary to control SRLV infections.

Changes in the Microbiome During Chronic Rhinosinusitis.

Chronic rhinosinusitis (CRS) is a common inflammatory disease of the paranasal sinuses with a yet unknown etiology. As studies continue to elucidate the disease's heterogeneity inflammatory profile and presentation, there is a growing interest in the influence of the nasal microbiome on disease pathogenesis and chronicity. The sinus microbiota appear dominated by the and genera; known upper airway pathogens, such as , are present in the upper airways of healthy individuals, though at relatively lower abundances than in CRS patients.

Microbial Dynamics in Endodontic Pathology-From Bacterial Infection to Therapeutic Interventions-A Narrative Review.

Endodontic infection is a penetration of microorganisms into the dental pulp. Bacteria are the most common entities that induce an infection. This state is associated with significant pain and discomfort.

Severe Cases of Tick-Borne Encephalitis in Northeastern Poland.

Tick-borne encephalitis (TBE) is the most prevalent viral infection of the central nervous system (CNS) in Poland. The disease is characterized by the presence of two stages. The first phase, called the viremic stage, presents with flu-like symptoms, while the second stage of TBE is characterized by damage to the nervous system and may follow a severe and dramatic course.

Computer-Aided Supporting Models of Customized Crack Propagation Sensors for Analysis and Prototyping.

The range of sensor technologies for structural health monitoring (SHM) systems is expanding as the need for ongoing structural monitoring increases. In such a case, damage to the monitored structure elements is detected using an integrated network of sensors operating in real-time or periodically in frequent time stamps. This paper briefly introduces a new type of sensor, called a Customized Crack Propagation Sensor (CCPS), which is an alternative for crack gauges, but with enhanced functional features and customizability.

The Application of Supervised Machine Learning Algorithms for Image Alignment in Multi-Channel Imaging Systems.

This study presents a method for aligning the geometric parameters of images in multi-channel imaging systems based on the application of pre-processing methods, machine learning algorithms, and a calibration setup using an array of orderly markers at the nodes of an imaginary grid. According to the proposed method, one channel of the system is used as a reference. The images from the calibration setup in each channel determine the coordinates of the markers, and the displacements of the marker centers in the system's channels relative to the coordinates of the centers in the reference channel are then determined.

Web Real-Time Communications-Based Unmanned-Aerial-Vehicle-Borne Internet of Things and Stringent Time Sensitivity: A Case Study.

The currently observed development of time-sensitive applications also affects wireless communication with the IoT carried by UAVs. Although research on wireless low-latency networks has matured, there are still issues to solve at the transport layer. Since there is a general agreement that classical transport solutions are not able to achieve end-to-end delays in the single-digit millisecond range, in this paper, the use of WebRTC is proposed as a potential solution to this problem.

Minimizing Delay and Power Consumption at the Edge.

Edge computing systems must offer low latency at low cost and low power consumption for sensors and other applications, including the IoT, smart vehicles, smart homes, and 6G. Thus, substantial research has been conducted to identify optimum task allocation schemes in this context using non-linear optimization, machine learning, and market-based algorithms. Prior work has mainly focused on two methodologies: (i) formulating non-linear optimizations that lead to NP-hard problems, which are processed via heuristics, and (ii) using AI-based formulations, such as reinforcement learning, that are then tested with simulations.

TARREAN: A Novel Transformer with a Gate Recurrent Unit for Stylized Music Generation.

Music generation by AI algorithms like Transformer is currently a research hotspot. Existing methods often suffer from issues related to coherence and high computational costs. To address these problems, we propose a novel Transformer-based model that incorporates a gate recurrent unit with root mean square norm restriction (TARREAN).

Effect of Embroidery Style on the Bandwidth of Textronic RFID UHF Transponder Antenna.

The production of consumer electronics using electrically conductive materials is a dynamically developing sector of the economy. E-textiles (electronic textiles) are also used in radio frequency identification technology, mainly in the production of tag antennas. For economic reasons, it is important that the finished product is universal, although frequencies in radio systems have different values in different regions of the world.

Reusable Biosensor for Easy RNA Detection from Unfiltered Saliva.

Biosensors are transforming point-of-care diagnostics by simplifying the detection process and enabling rapid, accurate testing. This study introduces a novel, reusable biosensor designed for direct viral RNA detection from unfiltered saliva, targeting SARS-CoV-2. Unlike conventional methods requiring filtration, our biosensor leverages a unique electrode design that prevents interference from saliva debris, allowing precise measurements.

Remote Radio Frequency Sensing Based on 5G New Radio Positioning Reference Signals.

In this paper, the idea of a radar based on orthogonal frequency division multiplexing (OFDM) is applied to 5G NR Positioning Reference Signals (PRS). This study demonstrates how the estimation of the communication channel using the PRS can be applied for the identification of objects moving near the 5G NR receiver. In this context, this refers to a 5G NR base station capable of detecting a high-speed train (HST).

Subwavelength Imaging in Sub-THz Range Using Dielectric Waveguide.

Terahertz radiation patterns can be registered using various detectors; however, in most cases, the scanning resolution is limited. Thus, we propose an alternative method for the detailed scanning of terahertz light field distributions after passing simple and complex structures. Our method relies on using a dielectric waveguide to achieve better sampling resolution.