NIR-Light Activable 3D Printed Platform Nanoarchitectured with Electrospun Plasmonic Filaments for On Demand Treatment of Infected Wounds.

Bacterial infections can lead to severe complications that adversely affect wound healing. Thus, the development of effective wound dressings has become a major focus in the biomedical field, as current solutions remain insufficient for treating complex, particularly chronic wounds. Designing an optimal environment for healing and tissue regeneration is essential.

The effect of silicon supplementation and drought stress on the deposition of callose and chemical components in the cell walls of the Brassica napus roots.

Background: Silicon has an important role in regulating water management in plants. It is deposited in cell walls and creates a mechanical barrier against external factors. The aim of this study was to determine the role of silicon supplementation in the synthesis and distribution of callose in oilseed rape roots and to characterize the modifications of cell wall structure of these organs after exposure to drought stress.

Terahertz Radiation Driven Nonlinear Transport Phenomena in Two-Dimensional Tellurene.

Nonlinear electron transport induced by polarized terahertz radiation is studied in two-dimensional tellurene at room temperature. A direct current, quadratic in the radiation's electric field, is observed. Contributions sensitive to radiation helicity and polarization orientation as well as polarization independent current are found.

Predictive models of injury risk in male professional football players: a systematic review.

Background: One of the challenges for professional football players is injuries. Due to their influence on their teams, injuries greatly impact the sports business. This research aims to assess predictive models of injury risk in male professional football players.

Dioxin-like polychlorinated biphenyls (dl-PCB) in hydrochars and biochars: Review of recent evidence, pollution levels, critical gaps, formation mechanisms and regulations.

Contamination of chars with dioxin-like polychlorinated biphenyls (dl-PCB) significantly limits their use and hinders their deployment in the circular bioeconomy, specifically in applications that may lead to dietary exposure. Here, for the first time, we review the levels of contamination of chars produced from pyrolysis and hydrothermal carbonisation (HTC) with dl-PCB congeners. We conduct a detailed and critical examination of the role played by the processing parameters, such as temperature and residence time, and the reaction mechanisms, to detoxify the biomass under an oxygen-free atmosphere during its valorisation.

Transformations in hydrological resilience: Unraveling the impact of landscape hydric potential on flood dynamics: A case study, Drwinka catchment (Poland).

Flooding remains a critical issue in urban catchments, driven by complex interactions between land use changes, hydrological dynamics, and environmental factors. This study aims to investigate how modifications in Landscape Hydric Potential (LHP) affect flood behavior in the Drwinka River catchment in Krakow, Poland. Given the rapid urbanization and its impacts on hydrological systems, understanding these changes is essential for effective flood management and mitigation.

An update on access to novel treatment for metastatic melanoma in Europe - A 2024 survey of the European melanoma registry and the European association of dermato-oncology.

Advances in cancer treatments have significantly improved their effectiveness, yet access to first-line therapies remains limited. A 2017 survey revealed that over 25 % of metastatic melanoma patients in Europe lacked access to recommended therapies. To address this, the European Association of Dermato-Oncology and the European Melanoma Registry conducted a follow-up study on the registration and reimbursement of first-line treatments.

Research note: Harnessing the potential of chicken blastodermal cells as a new frontier in poultry science and biotechnology - Establishment of embryonic stem cells and their differentiability towards Schwann cell-like cell lineages.

The nervous system's regenerative potential has sparked interest in exploring novel approaches to generate Schwann cell-like cells (SC-LCs) from chicken blastoderm (B)-derived embryonic stem cells (B-ESCs). This study investigates the hypothesis that specific growth factors, when used during ex-ovo culture, can induce the differentiation of chicken B-ESCs into cells resembling Schwann cells (SCs). Blastodermal cells (BCs) were isolated from in vivo-fertilized eggs at stage X followed by 14-d proliferative culture (PRC) of B-ESCs and subsequent 14-d glial/neurolemmogenic differentiation culture (DFC).

Antibiotics/coccidiostat exposure induces gut-brain axis remodeling for Akt/mTOR activation and BDNF-mediated neuroprotection in APEC-infected turkeys.

The poultry industry relies extensively on antibiotics and coccidiostats as essential tools for disease management and productivity enhancement. However, increasing concerns about antimicrobial resistance (AMR) and the toxicological safety of these substances have prompted a deeper examination of their broader impacts on animal and human health. This study investigates the toxicological effects of antibiotics and coccidiostats on the gut-brain axis and microbiota in turkeys, with a particular focus on molecular mechanisms that may influence neurochemical and inflammatory responses.

Prediction of ketosis using radial basis function neural network in dairy cattle farming.

The purpose of the paper was to apply an Artificial Neural Networks with Radial Basis Function to develop an application model for diagnosing a subclinical ketosis type I and II in dairy cattle. While building the neural network model, applied methodology was compatible to the procedures used in Data Mining processes. The data set was created based on the composition of milk samples of 1520 Polish Holstein-Friesian cows.

Patient passports and vulnerability: Disjunctures in health policy instruments for people with rare diseases.

Rare diseases have had a special status within European Union (EU) health policy since the late 1990s. According to key EU legal documents, rare disease patients are entitled to the same good quality care as others. These individuals are particularly vulnerable due to the "low prevalence" and "uniqueness" of their disease.

Moral-dilemma judgments by individuals and groups:Are many heads really more utilitarian than one?

Moral dilemmas often involve a conflict between action-options that maximize outcomes for the greater good (utilitarianism) and inaction-options that conform to moral norms (deontology). Previous research suggests that, compared to individuals, groups show stronger support for outcome-maximizing actions that violate moral norms. The current study used a computational modeling approach to investigate whether this difference is driven by (1) stronger sensitivity to consequences, (2) weaker sensitivity to moral norms, or (3) weaker action aversion in moral-dilemma judgments made by groups.

Cancer vaccines: an update on recent achievements and prospects for cancer therapy.

Decades of basic and translational research have led to a momentum shift in dissecting the relationship between immune cells and cancer. This culminated in the emergence of breakthrough immunotherapies that paved the way for oncologists to manage certain hard-to-treat cancers. The application of high-throughput techniques of genomics, transcriptomics, and proteomics was conclusive in making and expediting the manufacturing process of cancer vaccines.

The N-Acetyltransferase 2 Polymorphism and Susceptibility to Inflammatory Bowel Disease: A Case-Control Study.

The enzyme N-acetyltransferase 2 (NAT2) plays an important role in metabolism and detoxification of xenobiotics, including carcinogens and medications. We aimed to assess the contribution of the NAT2 polymorphism to susceptibility to inflammatory bowel disease (IBD) in the Polish population. The study involved 101 IBD patients and 100 healthy controls.

The influence of NOx, temperature, wind and total radiation on the level of ozone concentration in the Upper Silesian agglomeration.

In 2019, ozone was responsible for about 365,000 premature deaths worldwide (6.21 million healthy life years lost) and acute ozone exposure led to 16,800 premature deaths in the European Union. The aim of the study was to estimate the influence of NO, NO, wind direction (WD) wind speed (WS), air temperature (TA), and total radiation (GLR) on ozone concentration levels.

Comparison of sexual function between laparoscopic lateral suspension and laparoscopic sacrocervicopexy with the use of the PISQ-IR questionnaire.

Introduction And Hypothesis: We aimed to analyze the quality of sexual life of patients with apical vaginal wall prolapse who had undergone laparoscopic lateral suspension (LLS) and laparoscopic sacrocolpopexy (LSC).

Methods: We performed a secondary analysis of sexual outcomes of a previous randomized control trial comparing LLS and LSC in 89 women with symptomatic POP stage ≥ II. We evaluated sexually active (SA) and non-sexually active women (NSA) using the Pelvic Organ Prolapse/Incontinence Sexual Questionnaire-IUGA-Revised (PISQ-IR).

Pilot study on the dynamic interactions between cardiac activity and corneal biomechanics during eye movements.

Background And Objective: The study examines the relationship between ocular rotations and cardiovascular functions through detailed biomechanical analysis. The study documents specific patterns of ocular movements and their synchronization with cardiovascular activity, highlighting significant correlations. These findings provide a basis for understanding the opto-biomechanical interplay between ocular and cardiovascular dynamics.

Treatable traits in idiopathic pulmonary fibrosis: focus on respiratory tract infections-a systematic review and a meta-analysis.

Background: Idiopathic pulmonary fibrosis (IPF) is a progressive, deadly lung disease with several factors, including respiratory tract infections (RTI), for disease worsening. There's no comprehensive data on RTI incidence in IPF patients across different therapies, including antifibrotic (nintedanib or pirfenidone), investigative or placebo treatments.

Methods: A systematic search of databases Medline, EMBASE, Cochrane Central, Web of Science and Scopus was conducted on September 30th 2024 (PROSPERO registration number: CRD42023484213).

M-mode ultrasound evaluation of lateral abdominal muscle postural response to load: an exploratory study.

Aim: There is a need to evaluate the tissue deformation index of lateral abdominal muscles using M-mode ultrasound in a cohort of healthy subjects to establish a convenient reference point for clinical reasoning in patients. The aim of the study was to assess differences in the tissue deformation index between individual lateral abdominal muscles regardless of body side, compare these differences in the tissue deformation index on the right and left sides of the body, and evaluate side-to-side differences in the tissue deformation index within individual lateral abdominal muscles.

Material And Methods: In a group of 126 healthy volunteers (59 females), the postural response of lateral abdominal muscles to external perturbation in the form of rapid arm abduction with load was recorded on both sides of the body, and the tissue deformation index was calculated.

Diastasis recti in children - results of ultrasonographic study.

Aim: Diastasis recti is a common contour abnormality of the anterior abdominal wall, where an increased distance between the rectus abdominis muscles results in a visible or palpable bulge in this area. This study aimed to characterize this clinical entity in children.

Material And Methods: Anatomy of the rectus abdominis muscles and the linea alba, with a special focus on the interrectus distance (distance between two bellies of the rectus abdominis muscles), was studied using ultrasound.

Emerging cancer therapies: targeting physiological networks and cellular bioelectrical differences with non-thermal systemic electromagnetic fields in the human body - a comprehensive review.

A steadily increasing number of publications support the concept of physiological networks, and how cellular bioelectrical properties drive cell proliferation and cell synchronization. All cells, especially cancer cells, are known to possess characteristic electrical properties critical for physiological behavior, with major differences between normal and cancer cell counterparts. This opportunity can be explored as a novel treatment modality in Oncology.

New T-lymphocyte subpopulations and their characteristics: Challenges to the classical division of lymphocyte function.

Recent advances in immunology have challenged the conventional division of T-lymphocyte function by uncovering novel subpopulations with diverse roles and characteristics. This article reviews these discoveries and their implications for understanding immune regulation and disease pathogenesis. Innovative techniques have enabled the identification of previously unrecognized T-lymphocyte subsets, disrupting the classical classification system.

Indirect effects of the COVID-19 pandemic: A cause-of-death analysis of life expectancy changes in 24 countries, 2015 to 2022.

Worldwide, mortality was strongly affected by the COVID-19 pandemic, both directly through COVID-19 deaths and indirectly through changes in other causes of death. Here, we examine the impact of the pandemic on COVID-19 and non-COVID-19 mortality in 24 countries: Australia, Austria, Brazil, Bulgaria, Canada, Chile, Croatia, Czechia, Denmark, England and Wales, Hungary, Japan, Latvia, Lithuania, The Netherlands, Northern Ireland, Poland, Russia, Scotland, South Korea, Spain, Sweden, Switzerland, and the United States. Using demographic decomposition methods, we compare age- and cause-specific contributions to changes in female and male life expectancy at birth in 2019-2020, 2020-2021, and 2021-2022 with those before the COVID-19 pandemic (2015-2019).

Impact of lateral ankle sprains on physical function, range of motion, isometric strength and balance in professional soccer players.

Objective: Lateral ankle sprains (LASs) are prevalent in soccer and can affect long-term performance, injury recurrence and risk for chronic ankle instability. This case-control study examined functional impairments associated with LAS in professional soccer players aged 17-21.

Methods: 40 players were divided into 2 groups: 21 with a history of LAS and 19 healthy matched controls.