56 results match your criteria: "Pohang University of Science and Technology. Pohang[Affiliation]"
In vivo real-time confocal microscopy for target-specific delivery of hyaluronic acid-quantum dot conjugates.
Nanomedicine
October 2012
Department of Materials Science and Engineering, Pohang University of Science and Technology Pohang, Republic of Korea.
Unlabelled: Hyaluronic acid (HA), which is a biocompatible, biodegradable, and linear polysaccharide in the body, has been widely used for various biomedical applications. In this work, real-time bioimaging for target-specific delivery of HA derivatives was carried out using quantum dots (QDs). In vitro confocal microscopy of HA-QD conjugates confirmed the intracellular delivery of HA derivatives to B16F1 cells with HA receptors by HA-receptor-mediated endocytosis.
View Article and Find Full Text PDFDNA microarrays on nanoscale-controlled surface.
Nucleic Acids Res
July 2005
Department of Chemistry, Center for Integrated Molecular Systems, Division of Molecular and Life Sciences, Pohang University of Science and Technology Pohang 790-784, Korea.
We have developed new surface to ensure a proper spacing between immobilized biomolecules. While DNA microarray on this surface provided each probe DNA with ample space for hybridization with incoming target DNAs, the microarray showed enhanced discrimination efficiency for various types of single nucleotide polymorphism. The high discrimination efficiency holds for all tested cases (100:<1 for internal mismatched cases; 100:<28 for terminal mismatched ones).
View Article and Find Full Text PDFThe molecular and genetic control of leaf senescence and longevity in Arabidopsis.
Curr Top Dev Biol
September 2009
National Research Laboratory of Plant Molecular Genetics, Division of Molecular and Life Sciences, Pohang University of Science and Technology Pohang, Kyungbuk, 790-784, Korea.
The life of a leaf initiated from a leaf primordium ends with senescence, the final step of leaf development. Leaf senescence is a developmentally programmed degeneration process that is controlled by multiple developmental and environmental signals. It is a highly regulated and complex process that involves orderly, sequential changes in cellular physiology, biochemistry, and gene expression.
View Article and Find Full Text PDFDNA microarrays on a dendron-modified surface improve significantly the detection of single nucleotide variations in the p53 gene.
Nucleic Acids Res
June 2005
Division of Molecular and Life Sciences, Pohang University of Science and Technology Pohang 790-784, Korea.
Selectivity and sensitivity in the detection of single nucleotide polymorphisms (SNPs) are among most important attributes to determine the performance of DNA microarrays. We previously reported the generation of a novel mesospaced surface prepared by applying dendron molecules on the solid surface. DNA microarrays that were fabricated on the dendron-modified surface exhibited outstanding performance for the detection of single nucleotide variation in the synthetic oligonucleotide DNA.
View Article and Find Full Text PDFUnique Chemistry at Ice Surfaces: Incomplete Proton Transfer in the H(3)O(+)-NH(3) System This work was supported by the Creative Research Initiatives Project from MOST, Republic of Korea.
Angew Chem Int Ed Engl
April 2001
Department of Chemistry and Center for Ion-Surface Reaction Pohang University of Science and Technology Pohang, Gyeong-buk 790-784 (Republic of Korea).
Unique Chemistry at Ice Surfaces: Incomplete Proton Transfer in the H O -NH System.
Angew Chem Int Ed Engl
April 2001
Department of Chemistry and Center for Ion-Surface Reaction Pohang University of Science and Technology Pohang, Gyeong-buk 790-784 (Republic of Korea) Fax: (+82) 54-279-8157.