357 results match your criteria: "Plummer-Vinson Syndrome"

Article Synopsis
  • - Plummer-Vinson syndrome (PVS) is a rare condition characterized by iron deficiency anemia, esophageal strictures, and dysphagia, primarily affecting women aged 40-70.
  • - If left untreated, PVS can increase the risk of squamous cell carcinoma in the upper gastrointestinal tract or oral cavity, as illustrated by a case of a woman in her 50s who developed tongue cancer due to chronic dysphagia and untreated anemia.
  • - The article highlights the importance for dental surgeons to recognize the oral signs of anemia and to detect PVS early for better patient outcomes.
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Xanthogranulomatous Pyelonephritis and Plummer-Vinson Syndrome: A Case Report Exploring Potential Connections in a Single Patient.

Cureus

September 2024

General Medicine, Saveetha Medical College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, IND.

Article Synopsis
  • - Xanthogranulomatous pyelonephritis (XGP) mimics cancer and is a severe kidney infection, while Plummer-Vinson Syndrome (PVS) is characterized by swallowing difficulties, low iron levels, and esophageal webs.
  • - A case study of a 53-year-old woman with past kidney stones who exhibited symptoms indicating both XGP and PVS underscores the complexity of diagnosing these overlapping conditions.
  • - The case illustrates the importance of a multidisciplinary approach for accurate diagnosis and management, highlighting the links between chronic infections, malnutrition, and the development of neoplasms.
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Plummer-Vinson syndrome (PVS) is characterized by the classic triad of post-cricoid dysphagia, iron-deficiency anemia and esophageal webs. PVS is commonly found in women of middle age especially in the fourth and fifth decade of life. The prevalence of PVS has decreased due to early detection of iron deficiency and repletion of iron stores.

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Background: Plummer-Vinson syndrome (PVS) is characterized by a triad of symptoms consisting of microcytic hypochromic anaemia, oesophageal webs, and dysphagia. PVS is commonly found in women in the fourth and fifth decades of life and is rarely reported in the paediatric population.

Case Presentation: We report the case of a 1-year-old male South Asian child who presented with dysphagia and anaemia for 4 months and frequent episodes of vomiting after ingesting semisolid and solid food.

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Prevalence of Oral Submucous Fibrosis With Other Oral Potentially Malignant Disorders: A Clinical Retrospective Study.

Cureus

November 2023

Department of Oral Medicine, Radiology, and Special Care Dentistry, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences (SIMATS) Saveetha University, Chennai, IND.

Article Synopsis
  • - Oral submucous fibrosis (OSMF) is a serious, progressive oral disorder that can lead to cancer and is mainly found in Southeast Asia; the study investigates how often OSMF occurs alongside other potentially malignant oral disorders (OPMDs).
  • - It was found that having multiple OPMDs increases the risk of developing oral cancer significantly—three to four times for those with two OPMDs and seven to ten times for patients with three or more OPMDs.
  • - The research, conducted at Saveetha Dental College in Chennai, reviewed 630 patients with OSMF, revealing that 10% of them also had coexisting OPMDs, with leukoplakia being the most common. *
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Plummer-Vinson syndrome (PVS), also called Patterson-Kelly-Brown syndrome, is a rare cause of dysphagia in children. This syndrome is associated with single or multiple webs in the upper esophagus with frequent iron deficiency. PVS usually occurs in adults, particularly in Caucasian middle-aged women, in the fourth to seventh decade of life, and is rare in childhood.

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Blood comprises various cellular elements and serves as our immune system's second line of defense. Deviations from its normal composition can have adverse effects on health. At the same time, the oral mucosa in the oral cavity functions as the body's first line of defense, and any anomalies or diseases within it can give rise to both systemic and oral complications.

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A Chain Reaction to Dysphagia.

Gastroenterology

February 2024

CentraCare, Interventional Endoscopy Program, St. Cloud Hospital, St. Cloud, Minnesota.

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Could Plummer-Vinson Syndrome Be Associated with Celiac Disease?

Int Med Case Rep J

July 2023

Department of Health Communication Sciences, College of Health and Rehabilitation Sciences, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia.

Article Synopsis
  • * Initial suspicion was Plummer-Vinson syndrome due to the presence of esophageal webs and iron deficiency anemia; however, further tests indicated celiac disease as the underlying issue.
  • * After starting a gluten-free diet, the patient experienced weight gain and improvement in swallowing difficulties, highlighting the importance of screening for celiac disease in similar cases, even without diarrhea.
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Plummer-Vinson syndrome (PVS) or Paterson-Brown-Kelly syndrome is a rare clinical condition characterized by the triad of esophageal webs/stenoses, iron-deficiency anemia, and progressively worsening dysphagia. It occurs mostly in Caucasian women in the fourth to seventh decades, particularly in northern countries. Esophageal webs and stenoses can be encountered during endoscopic evaluation for the patient's complaint of dysphagia.

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Plummer Vinson syndrome (PVS) is a rare entity and most publications are case or series of cases. Thus, we report a series from southern Tunisia. Our aim was to analyse the epidemiological and clinical characteristics, the therapeutic modalities as well as the evolution of this pathology.

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[Hypopharyngeal carcinoma complicated with Plummer-Vinson syndrome: a case report].

Zhonghua Zhong Liu Za Zhi

February 2023

Department of Radiation Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.

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This retrospective study analyzed the occurrence of esophageal squamous cell cancer (ESCC) in a cohort of patients with Plummer-Vinson syndrome (PVS) and mucosal lichen planus (LP). ESCC occurred in 6.2% cases of PVS, more than half of whom had associated oral LP.

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Plummer-Vinson syndrome (PVS), the triad of dysphagia, iron-deficiency anemia (IDA), and esophageal webs, is a relatively rare disease entity that is mostly observed in the Caucasian populations of Scandinavia and North America. As these regions have become more developed with improved nutrition, PVS is now more commonly seen in the developing regions of the world. We present the case of a 29-year-old Pacific-islander woman who presented with progressive dysphagia and IDA and was found to have an esophageal web and  () gastritis on upper endoscopy.

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This study aimed to describe a patient with Sjögren syndrome who developed Plummer-Vinson syndrome, and to review the literature and describe shared aspects of this rare association. A systematic screening of articles was conducted in PubMed/MEDLINE, LILACS, SciELO, Scopus, Web of Science, and Cochrane, dating 1940 to 2020. All the articles included the association between Sjögren syndrome and Plummer-Vinson syndrome.

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Plummer-Vinson syndrome (PVS) presents with the classic triad of iron-deficiency anemia, dysphagia, and esophageal webs. The mainstay treatment of PVS is iron supplementation and the dysphagia usually responds to iron supplementation before the hematologic abnormalities are corrected. This syndrome classically affects middle-aged Caucasian women and very few cases have been reported in African Americans.

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